Objective To observe the therapetic effects of rotavirus enterocolitis by zedoary turmeric oil and glucose injection. Methods 120 cases were divided into therapatic group and control group at random,with 60 cases in each group. In the control group,ribavirin was used,while in the therapetic group,zedoary turmeric oil and glucose injection was added,without antibiotics in both groups. If dehydration were found,ORS or rehydration by vein would be used to rectify the disorder of water and electrolyte. Results In the therapetic group, it took much shorter time to stop diarrhea than the contrast group( P < 0.05 ). The difference between total disease processes of these two groups is extremely significant(P< 0.01 ). Conclusion Using zedoary turmeric oil and glucose injection with ribavirin to treat rotavirus enterocolitis has good therapetic effect. Key words: Rotavirus infections; Enteritis; Zedoary turmeric oil and gulcoee injection