Curcuma Xanthorrhiza Research Articles

Pre-exercise supplementation with curcuma xanthorrhiza roxb has minimal impact on red blood cell parameters but reduces oxidative stress: a preliminary study in rats.

This study examined the effects of longterm pre-exercise Curcuma xanthorriza Roxb supplementation on red blood cell indices along with circulating malondialdehyde (MDA) and superoxide dismutase (SOD) levels in response to endurance exercise to address previously inconsistent findings. Male Wistar rats (Rattus norvegicus; n = 20, aged 12-16 weeks) were divided equally into an exercise-only group (C) and three groups supplemented with Curcuma extract at dosages of 6.75 (T1), 13.50 (T2), and 20.25 mg (T3). Curcuma extract supplementation was administered for 28 d immediately prior to exercise. Following 28 d of exhaustive swimming, the hematocrit and erythrocyte count increased by 15% (p = 0.06). Pre-exercise Curcuma supplementation did not significantly affect mean corpuscular volume or mean corpuscular hemoglobin concentration. Longterm exercise intervention resulted in elevated MDA levels by 41% (p <0.001), while Curcuma supplementation (13.50 mg) attenuated this increase by 16.6% (p = 0.09). Additionally, Curcuma supplementation resulted in a dose-dependent increase in SOD levels, with an 82.6% increase observed at 20.25 mg (p = 0.028). Our preliminary findings indicated that pre-exercise supplementation with Curcuma extract had a negligible effect on changes in red blood cell markers, but it mitigated the increase in oxidative stress induced by exercise training. Our future research direction will involve applying the findings to humans.

Effect of Curcuma xanthorrhiza Extracts on the Phytochemical Content, Antioxidant Activity and Lactobacillus casei Growth

Curcuma xanthorrhiza (CX) has been reported as the most widely cultivated species in Southeast Asia. It is commonly found in the wild and has been traditionally used for medicinal purposes. The rhizome and root of CX contain constituents that offer various health benefits, including the treatment of skin inflammations and acne, as well as having antioxidant properties. Recently, numerous herbal products and traditional medicines made from CX have appeared in the market, available in forms such as capsules and bottled drinks. However, no research has yet validated the potential of growing Lactobacillus casei (L. casei) probiotic bacteria in CX extracts. The aim of this study is to determine the total phytochemical content of CX extracts, the antioxidant activity of CX extracts, and the prebiotic potential of CX. In this article, the chemical contents of CX, including total phenolics, total flavonoids, and antioxidant activity, have been studied using the Folin-Ciocalteu method, the aluminum chloride colorimetric method, and the DPPH free radical scavenging assay for antioxidant activity. The studies were conducted using three different methods of extracting CX: methanol-maceration, fresh juiced, and fresh boiled CX. The prebiotic potential of CX was studied using the L. casei probiotic strain. From the methanol-maceration extraction, the values of TPC and TFC are 111.55 ± 13.64 μg GAE/mg DW and 27.30 ± 7.75 μg QE/mg DW, respectively. Meanwhile, for the fresh juiced extraction, the TPC and TFC values are 30.513 ± 0.917 μg GAE/mg DW and 43.81 ± 5.13 μg QE/mg DW, respectively. Lastly, the boiled extraction method yields a TPC of 10.85 ± 0.21 μg GAE/mg DW and a TFC of 8.00 ± 0.49 μg QE/mg DW. At a concentration of 2000 μg/mL, the scavenging activity of the fresh juiced extraction reached a plateau of 89.33%. Meanwhile, at the same concentration, the scavenging effects of CX fresh methanol maceration and fresh boiled extraction are 61.39% and 49.81%, respectively. The L. casei strain was shown to be actively growing in CX extracts within the first 24 hours; however, after 24 hours, the growth remained almost constant. This may be due to the limited supply of CX extracts for the growth of the probiotic L. casei strain. Altogether, these results demonstrate that CX is a potential source of valuable bioactive compounds that could be used in medical, pharmaceutical, and food industries.

Peningkatan Kesehatan Masyarakat Melalui Inovasi Pengolahan Tanaman Apotek Hidup (Temulawak) Menjadi Puding Temulawak

Real Work Lectures (KKN) is a form of student service to society and is one part of the Tri Dharma of Higher Education. This KKN activity was carried out in Kalisemo Village, Loano District, Purworejo Regency. One of the work programs of KKN activities is socialization, here the KKN Team provides efforts to the community of Kalisemo Village, Loano District, Purworejo Regency in the form of transferring knowledge about the use of live apothecary plants (curcuma xanthorrhiza) by carrying out outreach activities to improve public health through innovations in processing live apothecary plants (curcuma xanthorrhiza) into ginger pudding. Pudding is a dessert that usually has a sweet taste, in contrast to curcuma which predominantly has a bitter and pungent taste. Using curcuma xanthorrhiza as pudding has various benefits, including increasing the body's immunity and increasing appetite. The target achieved from this activity is that the community is able to innovate in the use of live apothecary plants (curcuma xanthorrhiza) into a product that can increase entrepreneurial opportunities.

Pelatihan Pembuatan Produk Minuman Kesehatan Berbasis Bahan Alam dan Penyuluhan Regulasi Perijinan SPP IRT

The empirical utilization of plants as traditional medicine is still limited to making herbal decoctions which are rather long and on average taste bitter. The development of the utilization from medicinal plants in the form of health drinks that are easy to consume and taste acceptable to the public is still very low. Plant materials that are widely used include kencur in the form of herb beras kencur, temu lawak in the form of herb temu lawak. Therefore, this activity is to improve the health status for the community and increase the economic independence of the community by entrepreneurship with health drinks that are made from natural ingredients with innovative processing. The method that used in is counseling and hands-on practice of making, labeling products. The target audience is people whose daily activities are small entrepreneurs. The results obtained from this activity are increasing knowledge about the utilization of natural ingredients as health drinks, knowledge of SPP-IRT licensing regulations, and processing practices for making, packaging and labeling health drink products in the form of instant beras kencur, instant temu lawak and temu lawak syrup that have worth to sell.

The black cumin seeds oil with Curcuma xanthorrhiza extract preparation increases IFN-γ expression

Introduction: According to empirical evidence, Curcuma xanthorrhiza (CX) and black cumin (BC) have been utilized extensively in Indonesia. The primary components of Curcuma xanthorrhiza and black cumin (CXBC) formulations are BC oil and CX extract. This study aimed to assess the influence of CXBC active compounds (polyphenols, flavonoids, and thymoquinone) on IFN-g expression in HTB-183 cells. This study aimed to determine the levels of vitamins and minerals in CXBC preparation and the potential for immunomodulatory activities. Methods: We engaged in experimental laboratory research. Observing the expression of interferon-gamma (IFN-γ) was used to evaluate the immunomodulatory activities of the HTB-183 human large lung cancer cell line. Results: The results demonstrated that the CXBC supplement included vitamins (A, C, and E) and minerals (potassium, calcium). CXBC preparations boosted HTB-183 cell IFN-γ expression. Conclusion: The study's findings indicate that the CXBC formulation contains a high concentration of vitamins and minerals. CXBC formulations augment IFN-γ expression.

PELATIHAN PEMBUATAN MINUMAN HERBAL UNTUK MENJAGA KESEHATAN WANITA DI MASA PRODUKTIF

Women have complicated bodies. Throughout their existence, they go through the anatomical, physiological, and reproductive development processes. From birth to adulthood, there occurs development, and as a woman, the body's organs develop flawlessly and entirely. In comparison to a male, a woman's body develops differently, especially in terms of the reproductive organs, genitalia, endocrine system, and skeleton. The fast-paced and practical lifestyle elements of today's metropolitan society have an impact on the food ingested, which is bad for the body's health. The majority of high-risk illnesses, including heart disease, breast cancer, cervical cancer, osteoporosis, autoimmune disease, stroke, depression, and others, affect women more than males. The Community Service Partners are the management of the Family Welfare Development Team (TP-PKK) in West Bungo Village, Bungo Regency. The majority of PKK administrators, besides their activities as housewives, also work in government, private and entrepreneurial institutions, where due to business, consumption patterns and types of food eaten are unhealthy, such as fast- food which can be bad for the health of the body. especially reproductive health. Therefore, the purpose of this activity is to provide training and skills for TP-PKK administrators in making traditional herbal drinks with raw materials from rhizome plants such as Ginger, Turmeric, Temu Lawak, Kencur, Galangal which are very useful in helping to maintain body and reproductive health. in productive Ages.

Combination of black cumin seeds with Curcuma xanthorrhiza extract as an antioxidant and immune-modulator agent in the COVID-19 pandemic era

The COVID-19 pandemic demands changes in using of medicinal plants. Empirically, the medicinal plants of Curcuma xanthorrhiza (CX) and black cumin (BC) have been used massively in the era of the COVID-19 pandemic. Curcuma xanthorrhiza and black cumin (CXBC) preparations have been developed with the main ingredients of BC oil and CX extract. The purpose of the study was to determine the antioxidant and immune-modulatory activities of CXBC preparations active substances (polyphenols, flavonoids, thymoquinone). We conducted experimental laboratory research. The immunomodulatory activity test was carried out on human large lung cancer cell line (HTB-183 cells) by observing the expression of tumor necrosis factor alfa (TNF-α) and interleukine 10 (IL-10). The results showed that the CXBC preparation contained 4% thymoquinone, 25.87 mg/ml polyphenols, and 41.86 mg/dl flavonoids. CXBC preparations contain vitamins (A, C, and E) and minerals (potassium, calcium). The antioxidant activity of the CXBC preparation was included in the strong category with IC50=54.87 ppm. CXBC preparations increased TNF-a expression and decreased IL-10 expression in HTB-183 cells. Based on the study results, it can be concluded that the CXBC preparation contains 4% thymoquinone, 25.87 mg/ml polyphenol, 41.86 mg/dl flavonoid, and a high level of vitamin and minerals. CXBC preparations have potent antioxidant activity, increase TNF-α and decrease IL-10 expression.

Temulawak (Curcuma xanthorrhiza) Extract as a Cancer Chemopreventive Agent Via Up-Regulation p53 and Caspase-3 Gene

The development of biomaterials from herbs needs to be done as a chemopreventive compound to inhibit cervical cancer. Curcuma xanthorrhiza (CX) contains curcumin and xanthorrhizol, which are the main active substances for inhibiting carcinogenesis. Experimental research was carried out on cervical cancer cells from ethanol extracts of CX/EECX. Testing for proapoptosis potential by observing p53 gene expression in the HeLa cell was conducted by the flow cytometry method. Cytotoxic tests were carried out to obtained IC50, the results of 36.12 ± 6.66μg ml-1. The IC50 value is then made into three concentrations, namely, ½ IC50, IC50, 2xIC50. The ICC test results showed an increase in the p53 gene expression index in the 1/2IC50 and IC50 concentration groups. The expression of p53 in the IC50 concentration group was higher than that in the 1/2IC50 group. There were no living cells in the 2xIC50 concentration group, so p53 expression could not be seen. EECX has potential as a chemopreventive biomaterial to prevent cervical cancer because it increases apoptotic activity in HeLa cells. The possibility of cell apoptosis, which is influenced by EECX with the optimal concentration that can be used, is IC50, which is 36.12 ± 6.66 μg ml-1.

The commodity of Curcuma spp. sold in the traditional markets of Yogyakarta

Curcuma is a member of the Zingiberaceae family. In the traditional market, Curcuma soldby empon-empon trader. Previous research reported that some Curcuma species are rare to be found and were sold by traders. Therefore, there is a concern regarding the possibility of Curcuma spp. extinction. Research objectives are: (1) to find the number of empon-empon traders in Yogyakarta; (2) to know the percentage of the number of rhizomes found in traditional markets in Yogyakarta; and (3) to find whether the Curcuma species are found completely in the Yogyakarta traditional market. The research was conducted by exploration of traditional market in Yogyakarta. The data were analyzed by the Cochran test. Research results showed that the percentages of rhizomes are as follow: temu ireng (C. aeruginosa) (27.59%), temu giring (C. heyneana)(31.03%), turmeric (C. domestica) (93.10%), temu mangga (C. mangga) (27.59%), temu glenyeh (C. soloensis) (0%), temu lawak (C. xanthorrhiza) (64.29%), and temu putih (C. zedoaria) (17.86%), sold by empon-empon traders. Some Curcuma were rare in nature such as C. mangga, C. heyneana, C. purpuracens, C. soloensis, C. euchroma, C. colorata, and C. borg. The rhizome of Curcuma spp. is found to be incomplete in the traditional markets of Yogyakarta.

The ethnobotany of Zingibraceae as the traditional medicine ingredients utilized by Colo Muria mountain villagers, Central Java

Zingiberaceae is one of the natural resources used as a natural medicine by Colo Muria mountain villagers in Dawe District, Kudus Regency, Central Java. However, there is no particular study focusing on the use of the Zingiberaceae family in that area. This research aims to identify some species of the Zingiberaceae family utilized as a traditional medicine Colo Muria mountain villagers in Central Java. The data collection method is conducted by a semi-structured interview method, field observation, and documentation. The data was analyzed qualitatively. The result shows that there were 14 species utilized as traditional medicine by the Colo Gunung Muria villagers: Bangle (Zingiber purpureum Roxb), Ginger (Zingiber officinale), Red Ginger (Alpinia purpurata k. Schum.), Cardamom (Elettaria cardamomum (l.) Maton), Kencur (Kaempferia galanga L.), Kunci (Kaempferia pandurata Roxb.), Turmeric (Curcuma domestica Val.), Bitter Ginger (Zingiber zerumbet), Lengkuas (Alpinia galanga (L.) Swartz), Parahulu (Amomum aculeatum Roxb.), Temu Lawak (Curcuma xanthorhiza Roxb.), Temu Giring (Curcuma heyneana Val.), Temu Hitam (Curcuma aeruginosa Roxb.), and Temu Putih (Curcuma zedoaria Berg.). The processing technique of the plants was in two ways: pounded and boiled. While the methods of use were by drinking (61%), rubbed (22%), direct consumption (9%), dripped (4%), and dicethik (squeezed and dripped 4%).

Potensi Pengembangan Tanaman Obat-Obatan Di Pekarangan Sebagai Upaya Peningkatan Agroindustri Perkotaan

Abstract— The optimal use of yard is the best solution in providing added value for agro-industry products. One of the raw materials for agro-industry is medicinal plants. This study aims to determine the potential of medicinal plants planted in the yard and analyze the added value of medicinal plants grown in the yard into agro-industrial products. The method used is descriptive method that is applied in several regions that empower fruit, vegetable and medicinal plants as providers of agro-industrial raw materials, while the data analysis method uses the Value-Add Analysis method using the Hayami method (1987). After the research can be concluded as follows: (1) Identification of 15 types of medicinal plants, of which all types of medicinal plants can be used as agroindustry raw materials, namely Ginger, Turmeric, Sere, Pandan, Lengkuas, Aloe Vera, Kencur , Betel, Mustache cat, Tread Doro, Temu lawak, Temu Ireng, Kunci, Keji beling, Sambiroto. (2) Each research area has superior priority for the types of plants used as different raw materials, from the 3 highest priority sequences, namely: Ngawi Regency (Jahe, Kunyit, Sere), Magetan Regency (Ginger, Turmeric, Pandan) , Kabupaten Madiun (Ginger, Galangal, Turmeric), Madiun City (Ginger, Pandanus, Sere). (3) Processed products based on medicinal plants, namely Ginger into ginger syrup, are added value of Rp. 20250 - / kg, Turmeric plants become Jamu Kunyit in the amount of Rp. 19500 / kg, Pandanus plants become processed products of Pandan Dye amounting to Rp.46800 / kg. Keywords—: Medicinal Plants; Yard; Agroindustry.

Determination of Shelf Life of Herbal Products from the Combination of Stevia rebaudiana, Curcuma zanthorrhiza and Honey (Stekurmin MD) through the Accelerated Shelf Life Test (ASLT) Method

Stekurmin MD is a syrup preparation formulated from the extract of Stevia rebaudiana leaves, temu lawak (Curcuma zanthorrhiza), and honey. One of the active compounds in Stekurmin MD products is phenolic and flavonoid compounds in which the active phenolic and flavonoid compounds can be degraded during the storage period. This study aimed to determine the shelf life of Stekurmin MD products based on the degradation of phenolic compounds and flavonoids. The Accelerated Shelf Life Test (ASLT) method was used in determining the shelf life kinetics of this product. Phenolic and flavonoid concentrations were determined using the UV-Vis spectrophotometric method with the gallic acid standard for phenolic and quercetin standard for flavonoids. Degradation of phenolic and flavonoid compounds was determined every 7 days during 35 days of storage at 25, 35, 45, and 55°C ± 2°C. In natural ingredients, there is a multi-mechanism reaction. The shelf life of Stekurmin MD products based on the degradation of phenolic and flavonoid active ingredients at room temperature were 39.909 days and 23.53 hours, respectively.

MINUMAN FUNGSIONAL READY TO DRINK BERBAHAN BAKU REMPAH LOKAL

The purpose of this study was to study the extraction process of spices, obtain selected formulations based on organoleptic tests and physical stability tests. The research methodology is divided into two stages: the first stage is determining the composition of the spices (ginger, tamarind, turmeric, cardamom, lemongrass, cinnamon and cloves), using a one factor design that is the difference in the composition of the spices with 3 levels of treatment, namely (A1), (A2) and (A3) . The second stage uses the formula selected from the first stage and then is treated with 3 concentrations of spice extract (15%, 20% dan 25%) and the concentration of additional CMC (0%, 0.05% , 0.1% ). The results stated that the selected products were A3 composition spices (7.5% Curcuma xanthorrhiza extract, 25% tamarindus indica extract, 10% turmeric extract, 15% cardamom extract, 15% cinnamon extract, 15% lemongrass extract, 12.5% clove extract) with concentrations herbs 15% and CMC concentration 0.1%. This product was chosen because it was rated the most preferred. The results of physical stability analysis of selected products are quite stable with a sedimentation height of 0.04 cm on the 16th day. The selected product has a pH of 3.44, with a curcumin value of 13.70 ppm, and a total phenol of 31 ppm and an antioxidant of 2.97 ppm.

Quorum Sensing Inhibition Activity of Water Extract of Rhizome Herbs onAeromonas hydrophila

Several bacteria have been reported to be pathogenic to fishes, and some of them were opportunistic pathogen bacteria. Quorum sensing is a widespread phenomenon in bacteria on coordinating gene expression of virulence factors of bacterial pathogens, including biofilms. The aims of this research were to confirm biofilm formation by fish pathogenic bacteria, determine activity of water extracts of medicinal rhizome herb on growth and quorum sensing inhibition ofAeromonas hydrophila. Turmeric (Curcuma longaL.), temu lawak (Curcuma xanthorizaRoxb), ginger (Zingiber officinaleRoscoe), kencur (Kaempferia galangaL.) and galangal (Alpinia galangalL.) rhizomes were used in this study. The extracts were examined on their activity to affect growth and inhibition of biofilms formation byA. hydrophilaat concentrations of 40, 30, 20 and 10 mg/ml. Extract of rhizome medicinal herbs did not affect the growth ofA. hydrophila. Ginger extract at concentration of 40 mg /ml showed the highest inhibition of biofilm formation by 79.7%. Turmeric extract inhibited the biofilm formation by 59.9% at concentration of 30 mg / ml. Kencur extract showed the lowest biofilm inhibitory ability of 7.0%. The results showed the addition of plant rhizome water extracts had anti-quorum sensing activity as evidenced by inhibition of the formation of these bacterial biofilms.

Alkaline-based curcumin extraction from selected zingiberaceae for antimicrobial and antioxidant activities

PurposeThe purpose of this paper is to extract, characterise and quantify curcumin from selected Zingiberaceae of “kunyit” or turmeric (Curcuma longa), “temu lawak” or Javanese turmeric (Curcuma xanthorrhiza), “temu pauh” (Curcuma mangga), “lempoyang” (Zingiber zerumbet) and “bonglai” (Zingiber cassumunar) using alkaline and chemical-based extraction method for antimicrobial and antioxidant activities.Design/methodology/approachThrough the alkaline-based extraction method, all parts of rhizome samples were freeze-dried for 72 h before grounded into a fine powder and kept at −20°C. The powdered sample (0.1 g) was weighed and placed in a 50 mL tube. About 20 mL of 2 M NaOH solution was added into the tube. The solution was allowed to stand for 30 min. Then, 20 mL of ethyl acetate was added into the tube. The solution was mixed well then centrifuged at 13,500 rpm for 3 min. The upper layer was collected using a pipette. The process was repeated until the upper layer became almost colourless. The collected ethyl acetate solution was concentrated using a rotary evaporator to remove the ethyl acetate from the extracted compound. The concentrated curcumin was placed in a universal bottle, which was then dried from the remaining ethyl acetate using nitrogen drying process. The dried curcumin was then stored inside the freezer at −20ºC. The antimicrobial activities were using agar diffusion method against bacterial and fungi, while the antioxidant activity was evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging assay.FindingsAll the samples successfully showed a single peak (curcumin) that gained from the high-performance liquid chromatography (HPLC) chromatogram analysis (at 425 nm) using the alkaline-based extraction method and the highest curcumin content was in turmeric (12.95 ± 1.07mg/g DW). At 10.0 mg/mL curcumin concentration, the best antibacterial activity was against on methicillin-resistant staphylococcus aureus (MRSA) with 7.50 ± 0.71 mm inhibition zone, while the best antifungal activity was against on Aspergillus niger with 8.00 ± 0.41 mm inhibition zone. The DPPH antioxidant test resulted in the highest inhibition (110.41 per cent) was at 0.25 mg/mL curcumin concentration.Originality/valueThrough HPLC analysis, all samples successfully showed a single peak of curcumin at 425 nm. The total carotenoid determination from turmeric revealed that the samples content was substantially higher using alkaline-based extraction (18.40 ± 0.07 mg/g DW) compared to chemical-based extraction (9.42 ± 0.20 mg/g ± SD).

SELECTIVE ANTICANCER ACTIVITY OF CURCUMA XANTHORRHIZA FERMENTED JUICES

Objective: The objective of this study was to investigate the anticancer activity and toxicity of fermented juices from six Thai plants, Garcinia mangostana Linn., Tinospora crispa Linn., Litchi chinensis Sonn., Dimocarpus longan Lour., Curcuma xanthorrhiza (CX) Roxb., and Averrhoa bilimbi Linn., in normal cells as compared with common commercial fermented juices.Methods: The plants were fermented for 3 months, and their biological activities including 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) scavenging, metal chelating, lipid peroxidation inhibition, and tyrosinase inhibition activities were subsequently evaluated. Furthermore, their in vitro anticancer activities in human colon adenocarcinoma (HT-29), cervical cancer (HeLa), hepatocellular carcinoma (HepG2), and murine melanoma (B16F10) cell lines and their toxicities in normal human skin fibroblasts were assessed.Results: The fermented juice of CX showed a higher antioxidant activity than those of the other plants, with an SC50 (DPPH scavenging) value of 0.011 mg/mL, an IPC50 (lipid peroxidation inhibition) of 0.027 mg/mL, an MC50 (metal chelating) value of 0.170 mg/mL, and an IC50 (tyrosinase inhibition) of 0.027 mg/mL. Moreover, the fermented juice of CX displayed selective toxicity in cancer cell lines (HeLa, HepG2, and B16F10), with a significantly lower toxicity in normal human skin fibroblasts as compared with an expensive commercial fermented juice product.Conclusion: The present study suggests that the fermented juice of CX can be developed as a functional food supplement with antioxidant properties or as an anticancer product with low toxicity to normal human skin fibroblasts.

KAJIAN ETNOBOTANI RAMUAN PASCA MELAHIRKAN PADA MASYARAKAT ENGGANO

This research was aimed to discover the traditional knowledge of Enggano people when using plants as concoction after giving birth. Data was collected through in depth interview, open-ended, and literature studies. The results showed that Enggano people used specific plants as concoction in childbirth process. There were two types of the concoction. The first was used after giving birth to 40 days, jarak pagar or tiarak (Jatropha curcas L.). The second was used after 40 days to 60 days or after recovery, such as dukung anak (Phyllanthus niruri Linn.), kumis kucing (Orthosiphon stamineus Benth.), temu lawak (Curcuma xanthoriza Roxb.), alang-alang (Imperata cylindrica (L) P. Beauv.), banana (Musa sp.), kencur (Kaempferia galanga L.), turmeric (Curcuma longa L.), and ginger (Zingiber officinale Roscoe). Results from our literature studies confirmed the efficacy of plants used by Enggano people is scientifically acceptable. Further study on phytochemical aspects of these medicial plants is therefore required to be carried out.

Edukasi Manfaat Tanaman Obat dan Pengolahannya dengan Metode CBIA di Desa Bulusulur, Kabupaten Wonogiri, Jawa Tengah

The community service program reported in this paper aims to educate people about benefits of herbs and how to process herb raw materials for medication. This community service program was conducted in December 2016. The program involved 25 leaders of housewife communities (Kader PKK) in Bulusulur Village, Wonogiri, Central Java. The education was conducted using the CBIA (Cara Belajar Ibu Aktif) method. The CBIA supports the participants to be active during the education process. Results of the active learning through the CBIA method showed participants knowledge as folows: (1) participants were able to mention that herbal medicines are safe, have no side effects, can be easily obtained around their house; (2) they commonly used herbal for medication more than 4 times per month, obtained from their garden or local market; (3) they were able to mention the benefits of herbs commonly used; for example, temu lawak for stomachache, kunyit for pre-menstrual pain. However, they were not able to differentiate categories of herbal medicines which were produced by herbal manufacturers, such as Jamu, Obat Herbal Terstandar, and Fitofarmaka. Their knowledge about benefits of herbs was limited to those which were available in their garden. They also appreciated the demonstration of producing Bir Jawa and Sambiloto cookies.

Edukasi Manfaat Tanaman Obat dan Pengolahannya dengan Metode CBIA di Desa Bulusulur, Kabupaten Wonogiri, Jawa Tengah

The community service program reported in this paper aims to educate people about benefits of herbs and how to process herb raw materials for medication. This community service program was conducted in December 2016. The program involved 25 leaders of housewife communities (Kader PKK) in Bulusulur Village, Wonogiri, Central Java. The education was conducted using the CBIA (Cara Belajar Ibu Aktif) method. The CBIA supports the participants to be active during the education process. Results of the active learning through the CBIA method showed participants’ knowledge as folows: (1) participants were able to mention that herbal medicines are safe, have no side effects, can be easily obtained around their house; (2) they commonly used herbal for medication more than 4 times per month, obtained from their garden or local market; (3) they were able to mention the benefits of herbs commonly used; for example, “temu lawak” for stomachache, “kunyit” for pre-menstrual pain. However, they were not able to differentiate categories of herbal medicines which were produced by herbal manufacturers, such as “Jamu”, “Obat Herbal Terstandar”, and “Fitofarmaka”. Their knowledge about benefits of herbs was limited to those which were available in their garden. They also appreciated the demonstration of producing “Bir Jawa” and “Sambiloto cookies”.

Potensi Penetralisir Radikal Bebas Rimpang Temu Lawak (Curcuma xanthoriza Roxb.) dan Temu Ireng (Curcuma Aerugonosa Roxb.)

&lt;p&gt;Solvent with different polarity used used in extraction of antioxidant compound from temu Lawak &lt;em&gt; &lt;/em&gt;(&lt;em&gt;Curcuma xanthoriza Roxb.&lt;/em&gt;) and Temu Ireng (&lt;em&gt;Curcuma Aerugonosa Roxb.&lt;/em&gt;) spices. The solvent are Enthanol and acetone. Antioxidant extracts were analyzed in “neutralizer free radical” activity with DPPH Radical Scavenging Method. The activity compared with synthetic antioxidant BHA.&lt;/p&gt;&lt;p&gt;Result of the research perform that Temu Lawak and Temu Ireng spices were potential as neutralizer free radical. Antioxidant extract of Temu Lawak spices have higher activity than Temu Ireng spices extract. The “neutralizer free radical” activity of 1% Temu Lawak extract is 1,9 times 300 ppm BHA activity, and 1% Temu Ireng extract is 1,24 times 300 ppm BHA activity. Solvent influential at “neutralizer free radical” activity of Temu Ireng spices extract, but it doesn’t influential at Temu lawak spices extract.&lt;/p&gt;