Childhood bullying is a public health concern. The stability and changes in children's bullying profiles should provide useful information about specific risk groups and their developmental patterns. The current longitudinal study examined the stability and changes in bullying involvement in children along with the predictive roles of depressive symptoms in bullying subgroup memberships and transitions. A total of 4,321 Chinese children (55.1% male, Mage = 9.93) participated in self-report assessments at three time points with six-month intervals. Bullying subgroups were identified based on physical, relational, and cyberbullying using latent profile analysis. The transitions patterns were modeled using latent transition analysis. Depressive symptoms were added as a covariate in bullying subgroup memberships and transitions. Five bullying subgroups were found at Time 1 and Time 2: traditional bully-victims, traditional victims, (cyber) bully-victims, (cyber) victims, and noninvolved children, whereas four bullying subgroups were found at Time 3: traditional bully-victims, traditional victims, (cyber) bully-victims, and noninvolved children. Findings suggested that (a) childhood bullying involvement showed varying levels of stability, with noninvolved children displaying the most stability and cyberbullying-involved children displaying the least stability; (b) children reporting more severe depressive symptoms manifested a higher risk of bullying involvement; (c) initially noninvolved children showing depressive symptoms were at a higher risk for becoming traditional victims; and (d) children reporting depressive symptoms found it more difficult to escape from bullying than children without depressive symptoms. The findings offer support for both the cumulative continuity and interactional models of development. The findings also highlight the important the role of depressive symptoms in preventing and ameliorating children's bullying.