A 32-year-old male status post laparoscopic appendectomy 2 weeks prior presented to the emergency department with chief complaint of right-sided flank pain over the past 1 day. He denied any other associated symptoms. Vital signs were unremarkable. Physical examination revealed tenderness of the right flank and right lower abdominal quadrant. However, the abdomen was without rebound, guarding, or peritoneal signs. Renal point-of-care ultrasound (POCUS) was performed at the bedside to evaluate for a possible obstructive urinary process; POCUS demonstrated moderate hydronephrosis of the right kidney (Figure 1A and 1B). Focused abdominal POCUS then was performed to evaluate for possible postoperative complications; POCUS demonstrated a large anechoic fluid collection within the right lower abdomen, most suggestive of an intraabdominal hematoma (Figure 1C and 1D). General surgery was immediately consulted due to the abnormal POCUS findings. Computed tomography (CT) of the abdomen/pelvis confirmed a 12.6 × 10.9 × 9.3 cm fluid collection located in the right lower abdomen consistent with a postoperative hematoma, with resultant compression of the right ureter causing moderate hydronephrosis of the right kidney (Figure 2). The patient was subsequently brought to the interventional radiology suite for CT-guided hematoma aspiration and surgical drain placement. Obstructive uropathy secondary to post-appendectomy complication of an intraabdominal hematoma. Appendectomy is one of the most common abdominal surgical procedures performed in the United States and worldwide.1, 2 Post-appendectomy complications include surgical site infections, intraabdominal abscesses, ileus, bowel obstructions, adhesions, postoperative bleeding/hematomas, and urinary tract infections.2-4 Rapid diagnosis of postoperative complications is a critical yet challenging task for the emergency physician. POCUS is an invaluable non-invasive imaging modality available to the emergency physician in the bedside evaluation of a multitude of abdominal emergencies.5 To the best of our knowledge, this is the first case describing emergency physician-performed POCUS that identified a rare post-appendectomy complication of obstructive uropathy secondary to an intraabdominal hematoma. Most important, POCUS led to a timely diagnosis in this case, which prompted expeditious surgical consultation and further evaluation with gold-standard CT imaging. This report illustrates the promising role and clinical impact of POCUS as a first-line diagnostic choice in the initial ED assessment of patients with potential postoperative complications. The authors have nothing to disclose. This research was supported in part by HCA Healthcare and/or an HCA Healthcare affiliated entity. The views expressed in this publication represent those of the author(s) and do not necessarily represent the official views of HCA Healthcare or any of its affiliated entities.