Crystallinity Index Research Articles

Extraction and Characterization of Cellulose and Microcrystalline Cellulose from Teff Straw and Evaluation of the Microcrystalline Cellulose as Tablet Excipient

ABSTRACT Teff (Eragrostis tef), a grass which belongs to the Family Poaceae, is widely cultivated for its starch-rich grains in Ethiopia, generating large amounts of agricultural byproduct, teff straw. The aim of this study was to isolate and characterize cellulose and microcrystalline cellulose (MCC) from teff straw and evaluate MCC as directly compressible tablet excipient. Cellulose was extracted from teff straw and partially depolymerized to obtain MCC. The physicochemical properties of cellulose and MCC powders were characterized. Yields of cellulose and MCC powder from the raw material were 35.2% and 27.2%, respectively. The samples exhibited type-I crystal lattice and similar infrared spectra with that of Avicel PH-101. The degree of polymerization (DP) and crystallinity index of cellulose were 594.51 and 72.26%, respectively. Whereas, MCC powders showed DP of 241.09–257.38 and crystallinity indexes of 76.45–84.52%. Spray dried MCC was found to be more porous and poorly flowable and had higher moisture content when compared with the oven-dried MCC powder. Tablets prepared from both MCC powders fulfil most of the pharmacopoeial requirements. The spray-dried MCC powder also showed superior compactibility to oven-dried MCC. Teff straw can, therefore, be considered to be an alternative source of cellulose and MCC.

Optimum Yield of Empty Fruit Bunches Cellulose Nanofibers by Deep Eutectic Solvent and Ultrasonication

AbstractCellulose nanofibers (CNFs) are extensively utilized as affordable, renewable materials. The conventional technique for making CNFs is time‐consuming, requires hazardous toxic chemicals, and consumes enormous amounts of energy. CNFs from empty fruit bunches (EFB) were produced via deep eutectic solvent (DES) and ultrasonication. The DES treatment conditions were optimized using the central composite design (CCD) approach of response surface methodology (RSM). Analysis of variance (ANOVA) revealed that the reaction time, DES molar ratio, and temperature were all significant variables. The experimental results closely correspond to the theoretical model of CNFs yield. X‐ray diffraction (XRD) studies demonstrated that the crystallinity index of the CNFs increased significantly after sonication. It could be stated that DES treatment and ultrasonication were effective ways to successfully generate CNFs from EFB. This study may serve as foundation for high‐yield, industrial‐scale synthesis of nanocellulose using DES treatment.

Investigating the Mechanical, Thermal, and Crystalline Properties of Raw and Potassium Hydroxide Treated Butea Parviflora Fibers for Green Polymer Composites.

The only biotic factor that can satisfy the needs of human species are plants. In order to minimize plastic usage and spread an immediate require of environmental awareness, the globe urges for the development of green composite materials. Natural fibers show good renewability and sustainability and are hence utilized as reinforcements in polymer matrix composites. The present work concerns on the usage of Butea parviflora fiber (BP), a green material, for high end applications. The study throws light upon the characterization of raw and potassium hydroxide (KOH)-treated Butea Parviflora plant, where its physical, structural, morphological, mechanical, and thermal properties are analyzed using the powder XRD, FTIR spectroscopy, FESEM micrographs, tensile testing, Tg-DTA, Thermal conductivity, Chemical composition, and CHNS analysis. The density values of untreated and KOH-treated fibers are 1.238 g/cc and 1.340 g/cc, respectively. The crystallinity index of the treated fiber has significantly increased from 83.63% to 86.03%. The cellulose content of the treated fiber also experienced a substantial increase from 58.50% to 60.72%. Treated fibers exhibited a reduction in both hemicelluloses and wax content. Spectroscopic studies registered varying vibrations of functional groups residing on the fibers. SEM images distinguished specific changes on the raw and treated fiber surfaces. The Availability of elements Carbon, Nitrogen, and Hydrogen were analyzed using the CHNS studies. The tensile strength and modulus of treated fibers has risen to 192.97 MPa and 3.46 Gpa, respectively. Thermal conductivity (K) using Lee's disc showed a decrement in the K values of alkalized BP. The activation energy Ea lies between 55.95 and 73.15 kJ/mol. The fibers can withstand a good temperature of up to 240 °C, presenting that it can be tuned in for making sustainable composites.

Synthesis and characterization of phosphorylated cellulose nanocrystals for enhanced UV stability of epoxy nanocomposite films

Epoxy resins offer excellent chemical resistance, low-temperature curing, and low shrinkage. Despite these excellent properties, they are susceptible to UV degradation, which compromises their durability in outdoor applications. Herein, we fabricated a nanocomposite epoxy film based on phosphorylated cellulose nanocrystal (P-CNC) to improve the UV stability of cured epoxy resin by incorporating liquid ammonia-treated P-CNC into an epoxy matrix using integral blending method. Ammonium phosphate groups ((NH4)2HPO4) were formed by nucleophilic attack of phosphates by ammonia on the P-CNC surface. The functional groups, morphology, crystallinity index, and surface charges of P-CNC were characterized using Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), X-ray diffraction (XRD), and electrophoretic light scattering (ELS), respectively. The effect of P-CNC on the UV stability of the fabricated epoxy nanocomposite film was investigated using FTIR and UV–Vis before and after exposure to UV photons. The results showed that the incorporation of 1.0 wt.% of surface-treated P-CNC into the epoxy matrix maintained the UV stability of the nanocomposite film up to 800 h. Finally, a mechanism for UV stability of P-CNC epoxy nanocomposite film was proposed whereby the (NH4)2HPO4 groups grafted onto the P-CNC surface absorb UV photons and convert them into low-energy thermal energy or short wavelength electromagnetic waves, which are not sufficient to initiate photodegradation of the nanocomposite film. Thus, this new film provides resistance against UV degradation for extended service life for outdoor applications of epoxy resin.

Synthesis, Thermal and Mechanical Properties of Linear and Star Poly(L‐lactide)s

AbstractPoly(L‐lactide) with various architectures and molecular weights have been studied with respect to their thermal and mechanical properties. Their synthesis has been performed with an aluminum salen catalyst, which allows to obtain linear chains, tetrahedral 4‐arm stars and stars with two linked tetrahedra with 3 arms each, all with defined molecular weights. The polymers are characterized by their molecular weight distributions and then subjected to differential scanning calorimetry and thermogravimetric analyses, which show differences in the characteristic temperatures of not more than 10 degrees. The crystallinity index clearly increases with the weight of the chains with only a minor dependency on the topology. Thin films of the polymers are studied with respect to their elongation at break, their tensile strength, and their moduli. The elongation is most sensitive to the polymer type with a 15‐fold increase between the shortest linear polymer and the 6‐arm star polymer with the longest chains.

NANO-CRYSTALLINE CELLULOSE OF AFRICAN BEAN (PENTACLETHRA MACROPHYLLA BENTH) POD: EXTRACTION AND CHARACTERISATION

Nanocrystalline cellulose is a unique nanomaterial derived from the most abundant and almost inexhaustible natural polymer, cellulose. It is considered a sustainable nanomaterial due to its availability, biodegradability, and biocompatibility. Based on its desired structural, thermal, and morphological characteristics, it is suitable for mechanical and industrial applications. The research reports on the extraction and characterization of nanocrystalline cellulose from African bean (PentaclethramacrophyllaBenth) pods. In this paper, nano-crystalline cellulose (CNCs) were isolated from the cellulose extracted from Africa oil bean pod waste, followed by characterization using XRD, FT-IR, TGA, DGA, and SEM to determine its crystallinity, structural properties, thermal characteristics, and morphology, respectively. The result revealed that the Africa bean pod amorphous segments containing hemicelluloses and lignin were extensively removed with increasing chemical treatments, leading to increased purity, crystallinity index, and thermal stability of the extracted materials. The crystallinity index of nanocrystalline cellulose was estimated at 71.43%, which is better than both raw oil bean powder and isolated cellulose. This therefore implies that the nanocrystalline cellulose of the oil bean pod can serve different mechanical and structural applications.

INVESTIGATION OF MICROCRYSTALLINE CELLULOSES EXTRACTED FROM Thaumatococcus danielli and Ficus exasperata LEAVES

Cellulose is a vital raw material used in various industrial applications. Microcrystalline celluloses were extracted from de-waxed Thaumatococcus danielli and Ficus exasperata leaves through acid hydrolysis (1.5ml nitric acid), bleaching (12g sodium chlorite) and mercerization treatments (17.5% w/v sodium hydroxide). The properties of the extracted microcrystalline celluloses were examined with Fourier Transform Infrared Spectroscopy (FT-IR), Scanning Electron Microscopy-Energy/Dispersive X-ray Spectroscopy (SEM-EDX), Thermogravimetry/Differential Thermogravimetry (TGA/DTA) and X-ray Diffraction (XRD). The leaves were found to have appreciable amount of cellulose of 30 and 37.26 % for Thaumatococcus danielli and Ficus exasperata leaves respectively. The FT-IR results showed absorption peaks at 1017-1010 cm-1 which confirmed stretching vibration of C-O-C in Thaumatococcus danielli and Ficus exasperata celluloses. This corresponds to the SEM micrograph results that proved the removal of non-cellulosic components from the surface of the celluloses. EDX results revealed predominant intrinsic elements of the celluloses as carbon, oxygen with traces of silicon and iodine. Thermal analysis showed apparent weight loss of 78.37 and 81.31% at 380oC for Thaumatococcus danielli and Ficus exasperata celluloses correspondingly. XRD results revealed high crystallinity index of 91.5 and 84.8 % with an average crystallite size of 1.015 and 1.454 nm respectively. The properties of microcrystalline celluloses obtained suggest their applications as a potential stabilizer in cosmetic, pharmaceutical and biocomposite reinforcement.

Structural evolution of ultra-high molecular weight polyethylene gel film stretching at different temperatures with reservation of shish crystals

Shish crystal is the key structure to achieve low-dimensional ultra-high molecular weight polyethylene (UHMWPE) products with high performance. UHMWPE gel film containing shish crystals was prepared by precise temperature control in the gel molding, and its structural evolution in the stretching flow field at different temperatures was investigated by in-situ wide angle X-ray diffraction (WAXD)/small angle X-ray scattering (SAXS), scanning electron microscopy (SEM) and differential scanning calorimetry (DSC). It was found that shish crystals accelerated the structural evolution in both room and high temperature stretching, promoting more highly oriented crystals along the stretching direction. In room temperature stretching, the lamellae were deflected vertically to the stretching direction and gradually accumulated leading to a stabilization of the crystallinity index and the degree of orientation of the crystals along the stretching direction. However, in high temperature stretching, this intermediate orientation was broken and the transition to shish-kebab crystals continued, leading to a sharp increase in the crystallinity index and the degree of orientation of the crystals along the stretching direction.

Rice husk nanocellulose: Extraction by high-pressure homogenization, chemical treatments and characterization

Rice husk is a substantial agricultural by-product of rice milling and has potential as a rich source of cellulose. This cellulose can be synthesized into nanocellulose materials. In this study, rice husk nanocellulose materials were synthesized by high-pressure homogenization (HPH) or acid hydrolysis (AH) combined with HPH (AH+HPH) treatments with different HPH cycles (6, 9 and 12 cycles at 120 MPa). Various physicochemical techniques were employed to investigate the nanocelluloses. It was found that the number of HPH cycles directly affected the particle size, crystallinity index and thermal stability of nanocellulose samples. The mean diameter and length of the nanocellulose were 10.15–12.42 nm and 602.13–620.08 nm for HPH samples and 11.94–12.34 nm and 436.22–440.04 nm for AH+HPH treatment. The crystallinity index of the nanocellulose ranged from 62% to 72%. Morphological characterization of nanocellulose treated with HPH and AH+HPH revealed the successful production of cellulose nanofibers (CNFs) and cellulose nanocrystals (CNCs). EDX analysis confirmed that the nanocellulose comprised 40.06–42.34% carbon and 50.07–54.56% oxygen as the main mineral elements. Therefore, this research offers an alternative strategy to enhance the value of rice husks and facilitate the utilization in the food system for future research.

Paleoenvironmental changes in the coastal zone of the northwest South China Sea during the last 13 kyr

Marine sediments in coastal zones serve as valuable archives for understanding the history of silicate chemical weathering and summer monsoon rainfall in source areas, providing insights into terrigenous climate and environmental evolution. In this study, we investigated the grain size, clay minerals, and geochemistry of sediments retrieved from core KZK01 in the coastal zone of the northwest South China Sea during the past 13 thousand years before present (kyr BP). Our findings demonstrated that the illite crystallinity index served as a reliable proxy for assessing the intensity of chemical weathering in the source area. Moreover, it distinctly recorded significant climatic events such as the Younger Dryas and Bond events during the Holocene. The dominant driver of the regional East Asian summer monsoon was identified as summer solar radiation in the Northern Hemisphere at low latitudes. Cold climate events exhibited global consistency, potentially influenced by the presence of ice sheets at high latitudes. Lastly, our records revealed a distinct transition at 9.0 kyr, highlighting significant impacts of the Qiongzhou Strait and sea level rise on regional climate dynamics.

Transcriptome analysis of some genes of Staphylococcus aureus exposed to alkylated, nano- and native chitosans

Chitosan, including native, N- alkyl (AlkCs), and nanoparticles chitosan (CsNPs), were prepared and characterized. Average size and hydrodynamic diameter of nanoparticles were determined at 126 nm and 240 nm with a polydispersity index (PDI) of 0.154 and zeta potential of 30 mV, respectively. Crystallinity index for Cs, AlkCs, and CsNPs was calculated as 57.85, 30.24, and 24.85, respectively. Minimum concentration of growth inhibition (125.78 µg/ml) and lethality (100 µg/ml) was observed for CsNPs (P < 0.05). CsNPs and AlkCs showed the highest diameter of the growth inhibition zone at 1250 μg/mL concentration, respectively (P < 0.05). Membrane permeability test, the highest absorption of ortho-nitrophenol was observed after 90 min with 0.11 nm. The most significant decrease in absorption in chitosan was observed at the end of 120 min. DAPI (4′,6-Diamidino-2-Phenylindole) staining test showed higher cell death of bacteria treated with AlkCs and CsNPs. Images obtained from atomic force microscopy (AFM) showed a change in the morphology of the treated cells compared to the spherical and clustered control cells. A significant increase in the expression of vraS, vraR, lytM, lrgA and lrgB genes was observed as a result of induction of S. aureus cell wall by Cs, AlkCs and CsNPs, d.

Isolation of cellulose nanofibers from rapeseed straw via chlorine-free purification method and its application as reinforcing agent in carboxymethyl cellulose-based films

In this study, cellulose nanofibers (CNFs) were successfully isolated from rapeseed straw (RS) whose valorization has been rarely investigated to date. A combined bleaching method without chlorine was applied for the purification of cellulose fibers, previously unexplored for RS. Chemical composition analysis and Fourier-transform infrared spectroscopy (FTIR) indicated that the purification method eliminated hemicellulose and reduced lignin content from 24.4 % to 1.8 %. The isolation of CNFs was performed using sulfuric acid hydrolysis under different acid concentrations (55 and 60 % v/v) and hydrolysis times (15, 30, and 45 min). The isolated CNFs were characterized by FTIR, X-ray diffraction (XRD), scanning electron microscopy (SEM), and thermogravimetric analysis (TGA). The formation of CNFs was confirmed by a significant increase in crystallinity index from 46.45 % of RS to >79.41 % of CNFs, depending on acid concentration and isolation duration. Carboxymethyl cellulose (CMC) films with different contents of CNFs were prepared by casting method. The mechanical properties and cytotoxicity of the prepared films were investigated. The CNFs obtained from RS via a chlorine-free purification method showed promising results for their usage as reinforcement in CMC matrix and film fabrication for various applications such as transdermal medicine and food packaging.

Modification of Bulk Density, Flow Property and Crystallinity of Microcrystalline Cellulose Prepared from Waste Cotton.

The most affordable type of tablet is the immediately compressible tablet, which uses microcrystalline cellulose (MCC), a popular pharmaceutical excipient, as a filler or binder. To make it compatible with different active drugs and excipients, we tried to change some physical properties of the MCC. In the current study, we used a chelating agent to pretreat the waste cotton before pulping, bleaching, and finally, hydrochloric acid degradation with a concentration of 2N at 100 °C temperature for 20 min to prepare MCC. The prepared MCC was treated with different concentrations of sodium hydroxide at room temperature or at -20 °C followed by precipitation with hydrochloric acid or ethanol with complete washing with distilled water till neutralization. Evaluation of the degree of polymerization (DP) and FT-IR spectrum confirm the identity of the microcrystalline cellulose. The DP was found to be 216. The bulk density of the unmodified MCC was 0.21 while that of modified MCC varied from 0.253 to 0.594. The modified MCC powder showed good flow properties compared to the unmodified MCC as evaluated by the Hausner index, Carr's index and the angle of repose. The scanning electron microscopy (SEM) of the MCC revealed that the rod shape has been changed to an oval shape due to treatment with sodium hydroxide at -20 °C. The X-ray crystallographic (XRD) analysis indicated that the unmodified MCC and standard MCC showed the crystallinity index (CrI) value of 86.82% and 87.63%, respectively, while the value ranges from 80.18% to 60.7% among the modified MCC powder. The differences in properties of the MCC might be due to the variation of rearrangement of the cellulose chain among the MCC particles due to treatment with different concentrations of a base at different temperatures and precipitation environments. This has enabled us to prepare MCC with different properties which might be compatible with different drugs.

Electron beam irradiation-assisted prepare pea starch nanocrystals and characterization of their molecular structure, physicochemical and rheological properties

Electron beam irradiation (EBI) is an environmentally friendly physical modification technology. In this study, pea starch nanocrystals (SNC) were prepared by EBI-assisted pretreatment, and investigated the effects of EBI on the multiscale structure and physicochemical properties of SNC. EBI-assisted pretreatment didn't change the particle morphology, crystalline type and FT-IR spectra of SNC. However, EBI-SNC's relative crystallinity and short-range orderliness index (R1047/1022) significantly increased with increasing irradiation dose (5 KGy-20 KGy). In addition, EBI-assisted pretreatment caused the long chains of SNC's amylopectin to break into short chains. Moreover, EBI-assisted treatment significantly reduced the mean size, molecular weight, apparent amylose content, swelling power and SDS + RS content of SNC, while increasing the solubility, zeta potential and RDS content. Furthermore, the flow properties of the EBI-SNC samples were increased. The results show that EBI effectively changed the structural and functional properties of SNC, and the excellent functional properties are expected to broaden the application range of SNC.

Selective separation of hemicellulose from poplar by hydrothermal pretreatment with ferric chloride and pH buffer

As an environmentally friendly lignocellulosic biomass separation technology, hydrothermal pretreatment (HP) has a strong application prospect. However, the low separation efficiency is a main factor limiting its application. In this study, the poplar components were separated using HP with ferric chloride and pH buffer (HFB). The optimal conditions were ferric chloride concentration of 0.10 M, reaction temperature of 150 °C, reaction time of 15 min and pH 1.9. The separation of hemicellulose was increased 34.03 % to 77.02 %. The pH buffering resulted in the highest cellulose and lignin retention yields compared to ferric chloride pretreatment (FC). The high efficiency separation of hemicellulose via HFB pretreatment inhibited the degradation of xylose. The hydrolysate was effectively reused for five times. The fiber crystallinity index reached 60.05 %, and the highest C/O ratio was obtained. The results provide theoretical support for improving the efficiency of HP and promoting its application.

Structural Characteristics and Properties of Redissolved Silk Sericin.

Silk sericin has garnered the attention of researchers as a promising biomaterial because of its good biocompatibility and high water retention. However, despite its useful properties, the poor storage stability of sericin has restricted its extensive use in biorelated applications. This study extracted sericin from silkworm cocoon, dried and stored it as a solid, and then dissolved it in hot water conditions to improve the storage stability of sericin for its use. The dissolution behavior of the extracted sericin solids was examined in conjunction with the structural characteristics and properties of dissolved sericin. Consequently, the results of solution viscosity, gel strength, crystallinity index, and thermal decomposition temperature indicated that the molecular weight (MW) of the dissolved sericin remained constant until a dissolution time of 5 min, following which deterioration was observed. The optimum condition of dissolution of the extracted sericin solid was 5 min at 90 °C. Conclusively, the extracted sericin could be stored in a dry state and dissolved to prepare redissolved sericin aqueous solution with the same MW as extracted sericin, thereby improving the storage stability of the sericin aqueous solution.

A green approach for depolymerization of chitosan: applications in hydrogels

Chitooligosaccharides (COS) are depolymerized chains produced from the natural polymer chitosan and has been determined to exhibit improved biological activities, high solubility in neutral to slightly alkaline pH, because of the lower molecular weight (MW). This makes COS more attractive in biomedical applications. However, earlier studies focused on depolymerization techniques that were either cumbersome or expensive. Here, a convenient two-stage, green synthesis approach was developed and optimized, where gamma irradiation and oxidative degradation with H2O2 were used to depolymerize chitosan to produce COS for biomedical applications. The gamma radiation dose level, H2O2 degradation reaction’s temperature, time and H2O2 concentration were varied to obtain the mildest combination of reaction conditions. The most optimum set of conditions (15 kGy, 25oC, overnight reaction with 2% H2O2) yielded COS that was soluble in physiological pH range (7–8.5). The COS had a MW of 12.8 ± 1.6 kDa (which was a 95% reduction in MW), a 62.3% degree of deacetylation, and a crystallinity index of 33%. A photopolymerized hydrogel using this COS cross-linked with polyethylene glycol diacrylate (PEGDA) and carboxymethyl cellulose (CMC) was also developed. The hydrogel exhibited high swelling ratio (6.44–10.24), a porous morphology, a compression modulus of 4.5 ± 2.7 kPa (similar to soft tissues), and more than 95% biocompatibility with mammalian cells. This newly developed COS hydrogel involves a simple and green approach for the production of COS and shows promise as a scaffold for artificial soft tissue.

Microcrystalline Cellulose Isolation and Impregnation with Sappan Wood Extracts as Antioxidant Dietary Fiber for Bread Preparation.

Microcrystalline cellulose (MCC) has gained considerable attention as a functional ingredient in bread making. This work demonstrates the isolation of MCC from sugar cane bagasse (SCB) for preparing bread. The effect of MCC on bread attributes and antioxidant activity by impregnation with sappan wood extract (SAP) was evaluated. The highest crystallinity index and suitable size of MCC were achieved at 85 °C under 90 min hydrolysis condition. Increasing MCC/SAP levels in bread showed a significant increase in bread color with decreases in the specific volume and baking loss. There was a positive correlation between bread texture and the MCC/SAP level. The addition of MCC/SAP interfered with the bread hardness. Low MCC/SAP levels have no effect on springiness and cohesiveness; however, 4% MCC/SAP has significantly decreased these attributes, with the highest antioxidant activity and phenolic content. Therefore, MCC can be functionalized with SAP as an antioxidant fiber additive for health benefits in bakery products.

In-situ biofabrication of bacterial nanocellulose (BNC)/graphene oxide (GO) nano-biocomposite and study of its cationic dyes adsorption properties

In the present study, bacterial nanocellulose/graphene oxide nano-biocomposites (BNC-GO-NBCs) were fabricated by Komagataeibacter saccharivorans NUWB1 using an in-situ method involving three time-dependent approaches. Physicochemical studies showed that the chosen dried BNC-GO-NBC possessed a three-dimensional interconnected porous structure of BNC with GO layers embedded within the BNC fibrils. BNC-GO-NBC had a crystallinity index of 74.21 %, higher thermostability up to 380 °C and could withstand a tensile load of 84.72 MPa. N2 adsorption-desorption isotherm of the BNC-GO-NBC was found to be of type IV, suggesting a mesoporous type structure with a total pore volume and surface area of 6.232e-04 cc g−1 and 10.498 m2. BNC-GO-NBC exhibited remarkable adsorption capacity for two cationic dyes, Rhodamine B (RhB) and Acridine Orange (AO), and the adsorption data conformed well to the Langmuir isotherm (R2 = 0.99) and pseudo-second-order model. Thermodynamic studies indicated that the adsorption process was spontaneous and endothermic. Additionally, the BNC-GO-NBC displayed the potential for regeneration, with the ability to be recycled up to five times. Further, the antibacterial activity, cell cytotoxicity and oxidative stress assays of the BNC-GO-NBC revealed its non-cytotoxic nature. The findings of the present investigation evidently suggest the potentiality of BNC-GO-NBC in the application of dye adsorption and other environmental applications.

Oxidized Cellulose Nanocrystals from Durian Peel Waste by Ammonium Persulfate Oxidation.

Cellulose nanocrystals (CNCs) have gained much attention due to their biodegradable, renewable, nontoxic, and inexpensive nanomaterials with some remarkable properties. In this study, cellulose nanocrystals from durian peel waste were isolated by chemical oxidation. This process involved two stages of a chemical process, namely, bleaching followed by oxidation of ammonium persulfate (APS). The impact of process parameters (APS concentrations and oxidation temperatures) on the oxidized CNC was assessed. The properties of CNC were investigated by attenuated total reflection-infrared (ATR-IR) spectroscopy, X-ray diffraction (XRD), thermogravimetric analysis (TGA), and transmission electron microscopy (TEM). ATR-IR results showed that the structure of cellulose did not change during APS oxidation. XRD results indicated that APS oxidation improved the crystallinity index by 103% due to the removal of the amorphous components. The resulting CNC was needlelike in shape and had an average width range of 5.00-7.81 nm, a length range of 114.52-126.83 nm, and an aspect ratio range of 16.76-24.20. From the TGA analysis, the thermal stability was found to increase with increasing oxidation temperature. The optimum conditions for a maximum crystallinity index and the highest thermal stability were obtained at 80°C oxidation with 1 M APS. Therefore, APS oxidation was a remarkable method for increasing the value of durian peel waste into high-value nanocellulose.