Simulating crowd motion in emergency scenarios remains a challenge in computer graphics due to crowd heterogeneity and environmental complexity. However, existing crowd simulation methods homogenize the agent model and simplify target selection and motion navigation of emergency crowds. To address these problems, we propose a multi-agent motion simulation method for emergency scenario deduction. First, we propose a multi-agent model to simulate crowd heterogeneity. This model includes a personality-based heterogeneous agent model and an agent perception model that considers vision, hearing, and familiarity with the environment. Second, we propose a target selection strategy based on the motion patterns of actual pedestrians. This strategy employs mathematical models and our agent perception model to guide agents in selecting appropriate targets. Finally, we propose a global navigation algorithm that combines random sampling with heuristic search methods. Concurrently, we use our multi-agent model to adjust the agent’s local motion planning to naturally deduce the motion states of emergency crowds. Experimental results validate that our method can realistically and reasonably simulate crowd motion in emergency scenarios.