A novel sesquiterpene, crocaudatol(1) along with a known one, oplopanone (2) was isolated from the stems of Croton caudatus Geisel. var. tomentosus Hook.. The structure of 1 was determined by the analyses of HREI-MS, 1H-NMR, 13C-NMR, 1H-1H COSY, HMQC, HMEC and NOESY spectra. However, this structure was falsely assigned as homaloenal D whose structure was revised as 5-epi crocaudatol here by comparing the reported NMR data with those of 1.