Chemical fertilizer is necessary for the growth and development of crops. However, the efficiency of conventional chemical fertilizers is very low. Nowadays, fertilizer use efficiency (FUE) is the focus of agriculture cultivation practices to meet economic and environmental challenges. Around half of the total agricultural production relies on urea fertilizer, and the reduction in soil fertility has led to 3.56%. Liquid Nano Urea (LNU) can play a vital role in ensuring food security in Bangladesh. It can replace 50 % of conventional urea and can save subsidies to the govt. In addition, it is environmentally safe and reduces production costs, ensuring an increase in the total yield of 8-20%. Ensuring 90% work efficiency, the utilization of cutting-edge technologies and modern innovation in agricultural practices to enhance sustainability and efficiency in farming. Only two sprays of LNU can change the whole scenario of food safety. Recommended dose of optimize the use of nano urea for improved crop productivity and sustainability. The proper application of nano urea holds immense potential for enhancing crop production efficiency and sustainability.