The objective of current communication is to study heat transfer phenomenon for slip flow of viscous fluid due to wavy channel with general cosine function boundaries and fixed amplitude. The walls along with slip boundary constraints are kept at different temperatures. The flow is incompressible and Newtonian with AIS as a predicting material being used to check the fluids and thermal properties. The Navier–Stokes expressions with 2D flow regime subject to heat transfer due to convection are used to develop the simulations. A parametric theoretical assumptions analysis is performed for specified range of Reynolds number (100–1000) with upper and lower surface vibration periods of 1 to 6. The results are displayed with graphs, surface and contours plots and first, ever a novel work was done to represent the percentage change in velocity magnitude and local Nusselt number as surface plots and contours, respectively. The results are authentic due to mesh independent study and verification with the experimental correlation. A periodic flow at the lower wall was deducted. The maximum and average rotation rates attain a linear relationship with Reynolds number and their correlation was found. The simulations show the strict relationship of Reynolds number and the geometry of the channel with shear rate. The pressure gradient in [Formula: see text]-direction was found minimum in trough and maximum in the crest region. It has been observed that the boundary friction is reduced due to periodic variation of walls surface.