Creation Activities Research Articles

Development of Technology for the Synthesis of Nanocrystalline Cerium Oxide Under Production Conditions with the Best Regenerative Activity and Biocompatibility for Further Creation of Wound-Healing Agents

Background/Objectives: The issue of effective wound healing remains highly relevant. The objective of the study is to develop an optimal method for the synthesis of nanosized cerium oxide powder obtained via the thermal decomposition of cerium carbonate precipitated from aqueous nitrate solution for the technical creation of new drugs in production conditions; the select modification of synthesis under different conditions based on the evaluation of the physicochemical characteristics of the obtained material and its biological activity, and an evaluation of the broad-spectrum effect on cells involved in the regeneration of skin structure as well as antimicrobial properties. Methods: Several modes of the industrial synthesis of cerium dioxide nanoparticles (NPs) were carried out. The synthesis stages and the chemical and physical parameters of the obtained NPs were described using transmission electron microscopy (TEM), X-ray diffraction, Raman spectroscopy, and mass spectrometry. The cell cultures of human fibroblasts and keratinocytes were cultured with different concentrations of different nanoceria variations, and the cytotoxicity and the metabolic and proliferative activity were investigated. An MTT test and cell counting were performed. The antimicrobial activity of CeO2 variations at a concentration of 0.1–0.0001 M against Pseudomonas aeruginosa was studied. Results: The purity of the synthesized nanoceria powders in all the batches was >99.99%. According to TEM data, the size of the NPs varied from 1 nm to 70 nm under different conditions and methodologies. The most optimal technology for the synthesis of the nanoceria with the maximum biological effect was selected. A method for obtaining the most bioactive NPs of optimal size (up to 10 nm) was proposed. The repeatability of the results of the proposed method of nanoceria synthesis in terms of particle size was confirmed. It was proven that the more structural defects on the surface of the CeO2 crystal lattice, the higher the efficiency of the NPs due to oxygen vacancies. The strain provided the best redox activity and antioxidant properties of the nanoceria, which was demonstrated by better regenerative potential on various cell lines. The beneficial effect of synthesized nanoceria on the proliferative and metabolic activity of the cell lines involved in skin regeneration (human fibroblasts, human keratinocytes) was demonstrated. The antimicrobial effect of synthesized nanoceria on the culture of the most-resistant-to-modern-antibiotics microorganism Pseudomonas aeruginosa was confirmed. The optimal concentrations of the nanoceria to achieve the maximum biological effect were determined (10−3 M). Conclusions: It was possible to develop a method for the industrial synthesis of nanoceria, which can be used to produce drugs and medical devices containing CeO2 NPs.

Global value and wealth chains in contemporary capitalism: Editorial introduction

This introduction to a special section on global value chains and global wealth chains elaborates on the concept of entanglement as a way to understand dynamics of value capture, accumulation and inequality in contemporary capitalism. The authors first review the analytical framework they have proposed for analyzing entangled chains based on two dimensions: 1) the relative importance of intangible versus tangible assets; and (2) the primary strategy of lead firms – specifically, whether that strategy is oriented towards value creation or wealth accumulation activities. They then briefly discuss the four papers comprising this special section which collectively advance our knowledge of how production and finance are imbricated in the global political economy.

Aspects of the creation and judicial activity of the Specialized Chambers of Kosovo and the Role of the Republic of Albania

Abstract Since the end of the Kosovo conflict in 1999, various international and national courts have investigated serious war crimes and crimes against humanity in the region. In 2015, the Kosovo Specialized Chambers (SCK) and the Specialized Prosecutor’s Office (SPO) were established to investigate specific allegations of war crimes, particularly those linked to members of the Kosovo Liberation Army (KLA) during and after the conflict. Although the Court is legally part of Kosovo’s system, it faces strong opposition within the latter, due to its location outside the country and its exclusion of Kosovo nationals from its staff. The trials of key KLA figures, many of whom have held major political roles in the country, have sparked significant debate both in Kosovo and internationally. This manuscript will examine the legal foundation, structure, and scope of the SCK and SPO, and how they compare to other international courts. It will also review the indictments and ongoing trials of former KLA members. Additionally, the article will explore Albania’s diplomatic efforts, particularly its campaign to challenge allegations of organ trafficking mentioned in a 2011 Council of Europe report, which played a key role in the creation of the Court. By looking at the Court’s activities, the article will offer insights into its impact on Kosovo’s international standing.

Developing Brand Image (DeBI) dalam Membangun Citra Positif Lembaga Melalui Media Sosial

MAS Mirqotul Ulum faces challenges in developing its institution's brand image, especially through social media. Despite having a good reputation at the local level and having adequate facilities to support the development of its brand image, the madrasah has not fully utilized digital platforms to reach a wider audience and is still unable to formulate and implement effective strategies through social media. Facilities such as computer labs and good internet access can actually be used for digital marketing and content creation activities. Based on these conditions, it is important to implement the Developing Brand Image (DeBI) Program to build a positive image of the institution through social media at MAS Mirqotul Ulum Banyuanyar Probolinggo. Through four stages consisting of needs and potential analysis, training and workshops, strategy implementation, and evaluation and monitoring, the DeBI program has provided a strong foundation for MAS Mirqotul Ulum to continue to develop in the digital era. An in-depth SWOT analysis, effective training, and a targeted implementation strategy all contribute to the program's success. With the results achieved, MAS Mirqotul Ulum now has strong capital to continue and develop its digital communication strategy in the future.

The Changing Definition Of Human Nature From Traditional to Contemporary Approaches: A View Of Human Nature In The Philosophy Of Informatıon

The issue of what human nature is an important issue for understanding the present and building the future. The place of human beings in the universe as well as their duty, their relationship with society, and their environment has been shaped by the meaning attributed to human nature. This article examines the transformation that the understanding of human nature in traditional philosophy has undergone after the information revolution from the perspective of information philosophy. Information technologies, which have integrated into every area of our lives after the information revolution, has deeply affected our scientific, economic, intellectual, and cultural activities. With the information revolution, human nature has been redefined with its characteristics that participate in design and creation activities, thanks to its interaction abilities, which are information-processing capacities, beyond biological and spiritual characteristics. The understanding of human nature has been addressed in different historical periods since the mythological period. The subject here is to evaluate the understanding of human nature from the traditional to the present. The anthropocentric understanding of humans, traditionally defined in the context of biological, physiological, and spiritual characteristics, is defined in the philosophy of information in a holistic context as an agent with information processing capacity, an informational object. As an entity that carries and processes information, humans are evaluated in the same category as information technologies such as cybernetic systems and artificial intelligence, although they have different characteristics, as informational objects. In addition, this study aims to provide a new perspective to the literature by examining the change process in the understanding of human nature.

Beyond terroir: a comparative analysis of Pinot Noir producers and business strategies in Burgundy, New Zealand and South Africa

PurposeThis paper aims to examine the convergence and divergence of business and production practices in the global wine industry, particularly focusing on Pinot Noir producers in Burgundy, New Zealand and South Africa (SA). This study explores the interplay between firm-specific factors and regional contexts to identify competitive advantage drivers among Pinot Noir producers.Design/methodology/approachThis research uses a comparative analysis approach, using data from a comprehensive winery level survey. This study applies methodologies akin to value chain analysis to unravel the configuration of productive and technology/knowledge creation activities within wineries across three regions.FindingsThis analysis reveals both convergence and divergence in business and production practices among Pinot Noir producers in Burgundy, New Zealand and South Africa. Although there is a degree of convergence in marketing, distribution and competition strategies, differences exist in production practices and firms’ capabilities. Burgundy emphasizes tradition and terroir expression, contrasting with the modernization and innovation focus observed in New Zealand and South Africa. However, all regions share a commitment to quality as a competitive advantage.Research limitations/implicationsThis study acknowledges limitations such as the focus on a specific grape variety and regions, the absence of performance impact analysis and the need for additional variables like environmental, institutional and cultural factors and consumer preferences to provide a comprehensive understanding of industry dynamics.Practical implicationsThe insights from this study offer practical implications for winemakers, industry stakeholders and policymakers. Producers can optimize production and marketing strategies based on regional contexts and market segments, whereas stakeholders can identify emerging trends and opportunities in the global wine market. Policymakers can develop targeted policies supporting innovation, sustainability and competitiveness.Originality/valueThis paper provides a unique contribution by conducting a comparative firm-level analysis across distinct wine-producing regions, shedding light on the nuanced interplay of factors shaping competitive advantage among Pinot Noir producers. This study’s comprehensive data set and methodological approach enhance understanding and offer valuable insights for industry stakeholders and policymakers.

Edukasi SWADAIA: Swamedikasi Dispepsia Berbasis Kasus dan Video pada Masyarakat Desa Sungai Kakap, Kabupaten Kubu Raya

The prevalence of dyspepsia in Sungai Kakap Village is ranked third largest based on data from the Sungai Kakap Community Health Center, Kab. Kubu Raya with an incidence of 1,636 cases in 2023. One of the problems experienced by dyspepsia patients is inappropriate self-medication or self-medication. This Community Service Activity (PKM) is aimed at PKK members and Posyandu cadres because they are part of the community and are also an extension of health workers in helping solve problems experienced by dyspepsia patients. The method used in this PKM is case-based and educational videos. This PKM activity consists of several activities including preparation of activities; orientation and coordination of activities; selecting the target audience for educational media creation activities; providing pre-tests and cases at the beginning of activities; providing educational materials; discussion; post-test; evaluation of activity implementation; and data analysis. The output of this community service is publication in local electronic media in West Kalimantan (Suara Pemred/Tanjungpura Times), publication of scientific articles in the Sinta 4 accredited journal " PengabdianMu ", Copyright of educational videos and videos of implementation of activities on the FK UNTAN YouTube channel. The overall results obtained were an increase in knowledge of 27.19% with an average pre-test score (60.6) and post-test score (77.08). According to the evaluation of activities through questionnaires, participants considered the material presented to be very interesting, and the learning media provided was considered to provide new knowledge.

Follow the flow: An exploratory multi-case study of value creation in e-commerce ecosystems

Platform-based ecosystems dominate e-commerce, generating value through participant growth and resulting network effects. However, research has lacked any conceptualization of value creation in e-commerce ecosystems. This paper fills this gap by providing a theoretically grounded and empirically validated conceptualization of value creation and exchange, including roles, value creation activities, and value flows among participants. The model integrates insights from a systematic literature review and a multi-case study of ten leading e-commerce ecosystems. Furthermore, an extension to the e3-value notation is proposed by introducing ecosystem segments, allowing for a higher level of abstraction of meta-roles and individual ecosystem participants.

Tác động của hoạt động tạo thanh khoản đến khả năng sinh lợi của các ngân hàng thương mại Việt Nam

This study investigates the effect of liquidity creation activities on the profitability of Vietnamese commercial banks. The research sample includes 308 observations from 28 commercial banks in Vietnam from 2012 to 2022. The estimated results from models with random effects (REM), fixed effects (FEM), and feasible generalized least squares (FGLS) show that liquidity creation (LC) has a negative impact on the profitability of commercial banks in Vietnam. Further analysis shows that liquidity creation on the asset side (LCA), liquidity creation on the liability and equity sides (LCC), and liquidity creation on the off-balance sheet side (LCOBS) have a negative effect on the profitability ratio of Vietnamese commercial banks. This study provides some policy implications for bank managers regarding profit maximization strategies in Vietnamese commercial banks

Supporting the Primary Care Workforce Through Training in Advanced Generalist Practice: An Evaluation of the Catalyst Program.

As a workforce crisis is causing recruitment and retention issues for new to practice GPs, we designed Catalyst, a one-year pilot career development program aiming to help new to practice GPs develop the skills of advanced generalist practice and build capacity for the complex work of primary care. In this paper, we report the findings of our evaluation of Catalyst. We used normalization process theory to investigate how Catalyst was contributing to the participants' understanding and implementation of generalist practice. We conducted 36 interviews and six focus groups investigating the participants' clinical practice and experience with the program and analyzed data using framework analysis. Establishing a shared language and reframing professional identity helped GPs develop an understanding of their role through generalist lenses. Generalist practice was legitimized by access to scientific evidence and facilitated interactive learning. Integration of scientific, applied knowledge and quality improvement work fostered the enactment of such practice. Structured reflection and research-informed quality improvement projects contributed to the participants' awareness of the primary care context. Knowledge creation activities observed through interactive learning and the integration of different types of knowledge facilitated the implementation of advanced generalist practice. The participants valued the community of practice gained through the program and would come to rely on programs designed to encourage networking and enable peer support. Finally, research-informed quality improvement projects built to analyze problems and monitor solutions are crucial for an early career physician to develop a sense of agency that shapes their primary care practice.

Gender and business creation: similarities and differences

PurposeThis paper explores the scope and impact of gender in the process of starting new businesses, with a particular focus on understanding how participation, motivations and outcomes differ between men and women entrepreneurs.Design/methodology/approachThis paper utilizes data from the Global Entrepreneurship Monitor (GEM) and the Panel Studies of Entrepreneurial Dynamics (PSED). The GEM data provide a global overview, drawing from representative national samples across over 100 countries to assess the extent of business creation activity and gender participation globally. The longitudinal PSED data set provides information on the business creation process and outcomes.FindingsOver the last 20 years, the presence of women in the early stages of starting a business in the United States of America has seen a notable increase, doubling their representation among entrepreneurs and nearing parity with men, who also saw growth but at a slower rate. This shift marks a significant move towards greater gender balance in the entrepreneurial landscape.Originality/valueThe originality of this paper lies in its comprehensive analysis of the evolving landscape of gender dynamics within entrepreneurship over two decades, particularly highlighting the significant increase in women's participation in business creation.

Economic and social impact of affordable housing policies: A comparative review

Affordable housing policies play a pivotal role in shaping the economic and social landscapes of nations, especially in the context of growing urbanization and income inequality. This comparative review examines the economic and social impacts of various affordable housing policies across different countries, providing a comprehensive analysis of their effectiveness and broader implications. Economic impacts of affordable housing policies are multifaceted, influencing job creation, economic growth, and household stability. By increasing the supply of affordable housing, these policies can stimulate construction and related industries, leading to significant job creation and economic activity. Affordable housing also enhances household stability by reducing housing costs, allowing for greater disposable income and increased consumer spending. This review explores how policies such as tax incentives, subsidies, and inclusionary zoning have been utilized to promote affordable housing development and their resultant economic benefits. Social impacts of affordable housing policies are equally significant, affecting community cohesion, health outcomes, and educational attainment. Stable and affordable housing contributes to improved mental and physical health by reducing stress and exposure to poor living conditions. Furthermore, it enhances educational outcomes for children by providing a stable home environment conducive to learning. This review discusses policies such as rent control, public housing initiatives, and housing vouchers, highlighting their role in fostering social inclusion and reducing disparities. Case studies from diverse regions, including the United States, Singapore, and Brazil, illustrate the varied approaches and outcomes of affordable housing policies. In the United States, the Low-Income Housing Tax Credit (LIHTC) program has been instrumental in increasing affordable housing supply and promoting economic development in underserved areas. Singapore's Housing and Development Board (HDB) has successfully provided high-quality, affordable housing to a majority of its population, significantly enhancing social stability. Brazil's Minha Casa Minha Vida program showcases how large-scale public housing initiatives can address housing deficits and improve living standards for low-income families. The review concludes that while affordable housing policies have distinct economic and social impacts, their success largely depends on contextual factors such as policy design, implementation strategies, and local economic conditions. Policymakers must consider these factors to create effective and sustainable housing solutions that promote both economic prosperity and social well-being. Keywords: Economic, Social: Impact, Affordable Housing, Policies.

CONTOURS OF THE NOOSPHERE IN THE XXI CENTURY: A LOOK INTO THE FUTURE

The article attempts to comprehend the modern understanding of the noosphere, taking into account both the achievements of mankind in the creation of high technologies and the crisis phenomena that arise in the process of reaching the planetary stage of development. Destructive types of activity and human desire for creation are considered; the dominant types of human activities in relation to nature in different types of civilizations are indicated. The global noospheric aspect of intelligence was discovered, which reveals the noospheric unity of nature and humanity; content of noospheric intelligence as a civilizational asset; it shows the signs of noosphericity in the intellectuality of the individual; we foresee four stages of formation and development of noosphere society.

Integrating a mental health intervention into PrEP services for South African young women: a human-centred implementation research approach to intervention development.

Adolescent girls and young women (AGYW) who may benefit from HIV pre-exposure prophylaxis (PrEP) face high levels of common mental disorders (e.g. depression, anxiety). Common mental disorders can reduce PrEP adherence and increase HIV risk, yet mental health interventions have not been well-integrated into PrEP delivery. We conducted a four-phase human-centred design process, from December 2020 to April 2022, to understand mental health challenges among AGYW in Johannesburg, South Africa and barriers to integrated mental health and PrEP services. In the "Discover" phase, we conducted in-depth interviews with AGYW and key informants (KIs) in Johannesburg. We conducted a rapid qualitative analysis, informed by the Consolidated Framework for Implementation Research (CFIR), to identify facilitators and barriers of integrated mental health and PrEP services and mapped barriers to potential implementation strategies. In the "Design" and "Build" phases, we conducted stakeholder workshops to iteratively adapt an evidence-based mental health intervention, the Friendship Bench, and refine implementation strategies for South African PrEP delivery settings. In the "Test" phase, we piloted our adapted Friendship Bench package. Interviews with 70 Discover phase participants (48 AGYW, 22 KIs) revealed the importance of integrated mental health and PrEP services for South African AGYW. Interviewees described barriers and implementation strategies for mental health and PrEP services around the CFIR domains: intervention characteristics (e.g. challenges with AGYW "opening up"); outer Johannesburg setting (e.g. community stigma); inner clinic setting (e.g. judgemental healthcare providers); characteristics of counsellors (e.g. training gaps); and the implementation process (e.g. need for demand creation). The Design and Build workshops included 13 AGYW and 15 KIs. Implementation barriers related to the quality and accessibility of public-sector clinic services, lay counsellor training, and community education and demand creation activities were prioritized. This led to 12 key Friendship Bench adaptations and the specification of 10 implementation strategies that were acceptable and feasible in initial pilot testing with three AGYW. Using a human-centred approach, we identified determinants and potential solutions for integrating mental health interventions within PrEP services for South African AGYW. This design process centred stakeholders' perspectives, enabling rapid development of an adapted Friendship Bench intervention implementation package.

“We all contributed to tell stories to the best of our abilities”: collaborative digital storytelling to promote students’ positive interdependence in an online course of Italian as a foreign language

Positive interdependence is defined as a mutual relationship between people who are driven to achieve the same task goals- Considered as the foundation of collaborative language learning, it can surface in group activities of digital content creation. Digital storytelling may enhance skills of positive interdependence as it enables digital narratives to be told through mixed media (Robin, 2016). However, prolonged exposure to technology might cause distraction, motivation loss, and fatigue among language students, hampering the establishment of positive interdependence. To encourage interdependent interactions in digital learning environments, this study presents the results of educational activities conducted using the ThingLink and StoryMaps platforms by learners of Italian as a foreign language during an online language course. The results stemming from online questionnaires, transcript analyses, and focus group interviews highlight how students’ positive interdependence can be boosted by telling stories through immersive technologies.

Perancangan Website Sebagai Optimalisasi Media Promosi Sekolah Dasar Swasta Duri Indah Jakarta

Websites are the cheapest, most effective and efficient promotional media, because websites are online publication media for schools which are a necessity in providing information about products, price discounts and others and can also receive information quickly and accurately. SDS Duri Indah Jakarta until 2023 will always provide information regarding school activities and information regarding registration of new students via social media. Initial observations at SDS Duri Indah, the school does not yet have an independent website, so it is necessary to create and develop a website with the school domain (.sch). This website helps schools carry out promotions. Creation and assistance activities use several methods, namely 1) Observation, 2) Website creation, 3) Assistance with website management, 4) Monitoring and evaluation. The result of the activity is that the school has a school website and can also provide knowledge about managing school websites for admins and how to create articles and content for users.

Pembuatan Profile Kampung Mojo RW 10 Kota Surabaya

A village profile is needed to provide an accurate, comprehensive and integral picture of the village's potential and level of development. Through the University's Real Work Lecture activities on August 17 1945, we tried to help Kalidami RW 10 Village located in Surabaya City, East Java Province in an effort to create a village profile. Based on problem identification, the profile of Mojo RW 10 Village contains some information on the number of existing UMKM. However, there is some data that is still not complete or updated. For example, data that has not been updated is about Waste Generation, Village Profile, Waste Savings, etc. Therefore, the objectives of this service activity are: 1) creating a profile of Mojo RW 10 Village which contains complete village potential data and 2) presenting profile data of Mojo RW 10 Village which can be accessed in printed and electronic versions. The methods used are secondary data collection, surveys and interviews. Evaluation of this activity is carried out directly during the profile creation activity, so that output can be produced that meets the wishes of the target audience. The output of this activity is a printed book on the profile of Mojo RW 10 Village which is one of the documents available at the RW 10 hall and a video profile of Mojo RW 10 Village which has been uploaded on social media.

The Evolution of Traditional Picture Books: A Comparative Analysis Across Three Periods (2000-2005, 2006-2008, 2009-2022)

This research paper examines the evolution of traditional Chinese culture picture books over three distinct periods from 2000 to 2022. Drawing upon a comprehensive literature review and qualitative analysis, this study investigates the significant developments, trends, and changes in the portrayal of Chinese culture within picture books. The methodology involves identifying and analyzing notable works, authors, and techniques characteristic of each period. Through a comparative approach, this paper explores the similar shapes and differences of traditional Chinese cultural picture books over a period of three decades. The findings highlight changes in creative focus, the establishment of awards and institutions, and the activity of creation and publication, emphasising the dynamic nature of traditional Chinese cultural picture books. This study contributes to a deeper understanding of the role of picture books in promoting cultural heritage and fostering intercultural exchange. It also underscores the significance of preserving and promoting traditional Chinese culture through children's literature. The implications of this research extend to educators, scholars, and practitioners interested in multicultural education, children's literature, and cultural studies

생성형 인공지능(Generative AI)을 활용한 대중음악 창작교육 방안 연구 - ChatGPT 활용방안을 중심으로

The education curriculum for music composition utilizing generative AI, particularly ChatGPT, aligns with the new direction for improving creative and integrative abilities. This program is based on the enhanced capabilities in the musical realm brought by the upgrade to GPT 4.0, thereby allowing for personalized music creation support across various music genres and styles. The introduction phase focuses on learning to use AI and acquiring basic knowledge of popular music. The development phase involves undertaking creative tasks such as lyric, chord, and melody generation. In the conclusion phase, participants reflect on the process and share what they have learned. This study is significant as it serves as a model that provides concrete examples of music creation activities.

Smartbox Sebagai Media Pembelajaran Bagi Siswa MTs di Galeri Kreatif Bantur

The potential-Based Community Service Program (PMBP) aims to help develop human resources in the community, accompany children to learn and develop their respective talents and interests in midwifery. This service will start from March to May 2024. The target of the learning media creation activity is Madrasah Tsanawiyah students, The method used is learning by using learning media to deliver material about basic English vocabulary and the sport of football. From these activities it can be concluded that children will be more interested in exploring learning material with fun techniques, apart from eliminating children’s boredom when learning, learning media also provides many benefits for children and makes classes more interactive and fun, with media. learners, classes become more flexible and can be done anywhere and at any time.