The paper presents a description of the software and calculation complex that allows evaluatng the reliability, strength and stability of load-bearing structures of industrial buildings equipped with overhead cranes. It is built on the implementation of a consolidated algorithm aimed at the numerical solution of successively direct, inverse, and predictive problems of structural mechanics in a probabilistic formulation. The advantage of the complex is the possibility of forming for each design situation a large number of downloads, as well as the implementation and analysis of various schemes for their application with simultaneous action of components of the generalized load. The developed software and calculation complex acts as a tool for solving problems of computer processing of data obtained during a series of full-scale surveys of an industrial building equipped with bridge cranes aimed at determining the amount of residual life and the period of its trouble-free operation. Automating the calculation of indicators of reliability and durability in the dynamics of changes in their values, including in subsequent periods of operation of the facility, it becomes possible to predict emergencies and take timely measures to prevent them.