Topologically interlocked materials (TIMs) are an emerging class of architectured materials that each of block is supported by their neighboring blocks without any connector, which is inspired by microstructures observed in nature. Therefore, they showed alluring attributes such as resistance to impact, toughness, high flexibility even when using brittle materials, and high crack propagation resistance. In these structures, the presence of lateral compressive force, applied on peripheral blocks, ensures the integrity and identified properties. Lateral load, however, can adversely affect TIM plates and cause instability, and initiate buckling. In the present study, to focus on the buckling behavior of TIM plates due to the lateral force, a finite element model of TIM plates, made of tetrahedral blocks, was first validated using numerical results available in the literature and then analyzed. In this regard, an appropriate procedure has been presented to simulate the possible instability of these structures. Unlike monolithic plates, geometric parameters of TIM plates are dependent and this makes their parametric study more challenging. Therefore, some case studies have been accomplished to illustrate the effect of diverse parameters. The current study indicates that increasing the assembly plate length and decreasing its thickness causes a reduction of buckling load; nevertheless, it is necessary to mention that the thickness variation is a more impressive factor.