Abstract Purpose: As the world is learning to live with the coronavirus (COVID-19) pandemic, there is a shift in cancer control priorities and focus, with innovations to ensure continuity of cancer treatment and patient support during the COVID-19 pandemic. However, cancer control requires a comprehensive approach to minimize cancer incidence, mortality and improve the quality of life of those living with cancer. Hence, this analysis aimed to identify areas of cancer control affected by the COVID-19 pandemic that would equally affect cancer incidence, morbidity and mortality in Africa. Methods: The Africa Cancer Research and Control ECHO® Programme (Africa Cancer ECHO) is a community of practice that meets in an online platform to discuss cancer control challenges and solutions in the Africa region. The Africa Cancer ECHO conducted eleven sessions from April to August 2020 about the emerging COVID-19 pandemic, its impact on cancer control in Africa, and country-level practices as presented through case and didactic presentations. Sessions were analysed thematically to identify elements of cancer control that are adversely affected as a result of the COVID-19 pandemic and how they have been addressed. Results: HPV vaccination, cancer screening and early detection services, palliative care (PC) services, and cancer registration were particularly adversely affected, and in many cases have not yet resumed in some African countries. Recommendations included: use of affordable point of care HPV tests with immediate results; introducing COVID-19 testing along with HPV-testing; transitioning PC services from hospice to home care; and embracing Information Technology to enhance cancer registration. Conclusion: Cancer prevention, screening, supportive care, and surveillance services need to be urgently revitalised in Africa. The Africa Cancer ECHO platform highlights the need for generation of locally-relevant, evidence-based strategies that will safeguard past gains and continue to maximize the reduction of cancer incidence, morbidity and mortality during the COVID-19 pandemic. Citation Format: Annet Nakaganda, Nwamaka Lasebikan, Elise M. Garton, Benda Kithaka, Mishka K. Cira. Neglected Elements of Cancer Control During The COVID-19 Pandemic in Africa: Call for Action from 2019-2020 African Cancer Research and Control ECHO Programme [abstract]. In: Proceedings of the 9th Annual Symposium on Global Cancer Research; Global Cancer Research and Control: Looking Back and Charting a Path Forward; 2021 Mar 10-11. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2021;30(7 Suppl):Abstract nr 11.
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