<h3>To the Editor:</h3> —In an excellent summary of the present knowledge of carbon monoxid poisoning (The Journal, Aug. 19, 1916, p. 580), Prof. Yandell Henderson of Yale University suggests that "asphyxial coma... indicates an intense acidosis." No data were offered to support this conclusion, nor have I, in a cursory examination of the literature, been able to find evidence on this point. Through the courtesy of Dr. Joseph Roby, I have recently had an opportunity of studying the blood of a person suffering from intense carbon monoxid poisoning. The patient was a country girl, aged 17 years, residing in a boarding house. She had just come to the city to attend school, and was not familiar with the operation of gas fixtures. One night, through some inadvertence, she left the gas cock partly open. When found, she was unconscious and pulseless. She was taken to the hospital, where stimulants were