Need For Counseling Research Articles

Compound heterozygous ABCA12 variants identified in a Chinese patient with congenital ichthyosiform erythroderma: Advancing genotype-phenotype correlations and literature review.

Ichthyosis is a common keratotic skin disease with high clinical, etiological and genetic heterogeneity. There are four types of non-syndromic hereditary ichthyoses, among which autosomal recessive congenital ichthyosis (ARCI) is a heterogeneous group of recessive Mendelian disorders. ARCI present with different phenotypes and ABCA12 pathogenic variants have been shown to cause complex ARCI phenotypes, including harlequin ichthyosis (HI), lamellar ichthyosis (LI) and congenital ichthyosiform erythroderma (CIE). A sporadic male patient, clinically diagnosed with CIE, was enrolled in this study. Exome sequencing was combined with Sanger sequencing to confirm the diagnosis and identify the pathogenic variants. In silico predictions were made using multiple software programs, and the identified variants were interpreted using the ACMG guidelines. A review of all literature reported ABCA12 variants was performed to explore genotype-phenotype correlations. Compound heterozygous ABCA12 variants [c.5381+1G>A and c.5485G>C (p.Asp1829His)] (NM_173076) were identified. The two variants were not detected in the public database. c.5381+1G>A is predicted to affect ABCA12 mRNA splicing and Asp1829 is highly conserved among various species. In silico analysis suggested that these two variants were responsible for the phenotype of the patient. Genotype-phenotype correlation analysis showed that biallelic truncation variants and/or exon/amino acid deletions in ABCA12 are the most common causes of HI. Biallelic missense variants are most common in LI and CIE. The compound heterozygous ABCA12 variants caused the CIE phenotype observed in the patient. The spectrum of ABCA12 pathogenic variants were broaden. Genotype-phenotype correlation analysis provided detailed evidence which can be used in future prenatal diagnosis and can inform the need for genetic counselling for patients with ABCA12-related ARCIs.

상담자의 노인 상담에 관한 인식 연구

Although the number of older adults in need of psychological help is increasing due to the increase in their population in Korea, there is a shortage of counselors qualified to provide the appropriate services for them. In order to activate gerontological counseling, there is a great need to explore the counselors’ perception of counseling for the older adults. Accordingly, 75 counselors with at least two years of counseling experience after graduating from a master’s program were asked through an open-ended questionnaire about their perceptions of the characteristics, counseling process, and counseling outcomes for the older clients. The counselors responded to the questionnaire online and the response data were analyzed using Consensual Qualitative Research Analysis. There were a total of 647 statements collected, they were classified into 61 subcategories, and the subcategories were integrated into 4 themes and 17 categories. The first theme was named ‘the characteristics of the older clients,’ and the counselors generally perceived them negatively such as stubborn people. The second theme was named ‘their need for counseling,’ and the counselors thought that the older clients would consider the counselor as a sympathizer to their problem but not a counseling expert. The third theme was named ‘the gerontological counseling process’, and the counselors recognized that the personality traits of older adults such as resistance to change and the age difference with the clients would make the counseling process difficult. The fourth theme was named ‘the gerontological counseling outcome,’ and the counselors recognized that the mental health problems of the older clients would be resolved to some extent even if the counseling outcomes for them were not great. The findings of this study confirmed that general counselors have negative stereotypes about older clients or aging. The authors raised the need for training to correct this negative perception of counselors and strengthen counseling competencies for the older adults in a super-aged society where gerontological counseling becomes more and more important in the last part of this paper.

Psychological Distress and Students’ Academic Achievement in the Colleges of Education: Does Gender Matter?

Background: Students are exposed to a wide range of potentially stressful situations which could negatively affect their academic achievement and their health. The study examined the influence of psychological distress on students’ academic achievement in the Colleges of Education (CoE) in Ghana. Methods: Using descriptive cross-sectional survey design, 325 students were selected from six CoE using a multi-stage sampling procedure. Primary data was gathered using DASS-21 and analysed via SEM, Moderation analysis and independent sample t-test. Results: The study discovered that psychological distress (i.e., depression, anxiety, and stress) negatively significantly predicted the academic achievement of college students. Specifically, academic anxiety and stress has a negative influence on students’ academic achievement. However, gender does not moderate the relationship between psychological distress and academic achievement of the students. There was a significant gender difference in the psychological distress of students. Female students experienced a high level of anxiety and stress compared to male students. There was no gender difference in depression among students. Conclusion: School officials and teachers should intensify their academic interventions, workshops, and counselling to help reduce the psychological distress among students to improve mental health for academic excellence. Novelty: Study found that psychological distress, including depression, anxiety, and stress, negatively predicts the academic achievement of college students in Ghana, highlighting the need for academic interventions and counseling to improve students' mental health and academic performance.

Assessing nutrition literacy and nutrition counseling proficiency following an interdisciplinary culinary medicine elective.

Culinary medicine (CM) is a growing field of education that aims to bridge the gap between the clinical need for nutritional counseling and the lack of education on the topic. Healthcare professionals can aid in nutrition-related noncommunicable disease (NCD) prevention by improving a patient's dietary behavior. However, the presence of nutrition education in healthcare curricula is lacking. Early evidence indicates that CM could address this gap. The objectives of this study are to determine ifthe provision of an interdisciplinary CM elective will improve student knowledge and confidence with counseling on nutrition and culinary principles, and to improve personal dietary habits of students. This was a one-group pretest-posttest quasi-experimental design. First- and second-year osteopathic medical students (OMS) and nurse practitioner students were recruited to participate in a CM elective via email. Participants were excluded if they were not in good academic standing at their respective institutions. Twelve individuals (n=8 medical; n=4 nursing) were enrolled in the course. Participants completed pre- and postcourse surveys to determine changes in nutrition literacy (Nutrition Literacy Assessment Instrument [NLit42]), nutrition counseling proficiency (Nutrition Survey for Family Practitioners), and dietary quality (Automated Self-Administered 24-h dietary assessment tool; ASA24®). A two-sided, paired t test was conducted to determine changes in outcome variables. All 12 participants completed the precourse assessments, and 8 participants completed the postcourse assessments. Culinary activity attendance was 94.5 %. Participants exhibited a statistically significant increase in their overall nutrition literacy scores after completing the CM elective (p=0.006). Literacy subcategories indicated that the improvement came from the participant's ability to understand household measurements (p=0.005) better. Increases in self-reported proficiency were observed for participants' confidence to counsel on nutrition and prevention/wellness (p=0.02) and macronutrients in health and food safety (p=0.01). No statistically significant changes in the personal dietary pattern or quality were observed. The interdisciplinary CM elective improved nutrition literacy and some aspects of counseling proficiency. Although small shifts in dietary variables were observed, the elective did not statistically improve participants' dietary pattern. However, some changes that were observed may lead to clinically relevant outcomes if maintained long-term. These findings are encouraging. Implementing CM as an educational tool could improve healthcare practitioners' ability to understand and counsel patients on nutrition to prevent the nutrition-related NCDs.

E008 Review of rheumatology care for women of childbearing age

Abstract Background/Aims Autoimmune rheumatic diseases are frequently diagnosed in women of childbearing age. Managing these conditions during pregnancy is complex because commonly used disease-modifying antirheumatic drugs (DMARDs) can pose risks. Specialized care for this patient group is crucial, necessitating adherence to established rheumatology practice standards and British Society for Rheumatology (BSR) guidelines. Our main objective is to review management of childbearing age females with rheumatic diseases attending Basildon hospital as per BSR guidelines. Methods The data for this retrospective study was collected from the electronic records of female patients attending the rheumatology outpatient clinic at Basildon Hospital between September and December 2022. We reviewed age, the specific rheumatological diagnosis, disease duration, disease activity, current medications, and whether general advice or pregnancy-specific advice was provided. Results Out of the initial cohort of 63 female patients, 48 (76%) aged between 18-55 years were selected as women of childbearing age, The median age was 46 years, with 65% in the age groups of 31-50 years, 25% in group 51-55 years and 10% 18-30 years age group. 58% of patients had inflammatory arthritis, 18.7% had connective tissue disease, 18.7% had other conditions such as hypermobility, osteoarthritis, and regional pain syndrome, 2.3% were diagnosed with vasculitis and 2.3% with polymyalgia rheumatica. Breakdown of inflammatory arthritis patients revealed rheumatoid arthritis in 64%, psoriatic arthritis 15% and ankylosing spondylitis 12%. Axial spondyloarthropathy, palindromic rheumatism, and juvenile idiopathic arthritis, each accounted for 3%. Regarding prescribed medications, 66% of the individuals were on conventional DMARDs, biologics 24%, corticosteroids 6% and 4% were on other treatments. The DMARDs prescribed were methotrexate 27%, hydroxychloroquine 19%, sulfasalazine 13%, mycophenolate 3% and leflunomide 1%. The majority of patients had disease activity in remission or mild, each accounting for 23%. Moderate and severe disease activity were reported in 21% each of the audited sample. Patients received advice specifically related to pregnancy 29%, while 71% did not have documented pregnancy-related guidance. 70% of females of reproductive age received general advice. Conclusion The study highlights a gap in pregnancy-related advice among the childbearing age patients as only 29% received guidance on pregnancy. This underpins the need for proactive counselling and education for female patients in routine practice, work in partnership with obstetric teams, and primary care to reduce potential pregnancy related complications and improve outcomes. Disclosure M. Mohareb: None. S. Ahmed: None. A. Bharadwaj: None. A. Nandagudi: None.

Precise Prediction of Long-Term Urinary Incontinence after Robot-Assisted Laparoscopic Radical Prostatectomy by Readily Accessible "Everyday" Diagnostics during Post-Surgical Hospitalization.

Aim and Objectives: We aimed to test the predictive value of readily accessible and easily performed post-surgical "bedside tests" on their validity of long-term urinary incontinence (UI) (≥12 months) in patients following robot-assisted laparoscopic radical prostatectomy (RALP). Material and Methods: Patients undergoing RALP between July 2020 and March 2021 were prospectively included and subdivided into two groups based on their pad usage after 12 months (0 vs. ≥1 pad). After catheter removal, patients performed a 1 h pad test, documented the need for pad change in a micturition protocol and received post-voiding residual urine volume ultrasound. Univariate and multivariable analyses were used to demonstrate the predictive value of easily accessible tests applied after catheter removal for UI following RALP. Results: Of 109 patients, 47 (43%) had to use at least one pad (vs. 62 (57%) zero pads) after 12 months. Univariate testing showed a significant difference in urine loss between both groups evaluated by the 1 h pad test performed within 24 h after catheter removal (70% < 10 mL, vs. 30% ≥ 10 mL, p = 0.004) and in the need for pad change within the first 24 h after catheter removal (14% dry pads vs. 86% wet pads, p = 0.003). In multivariable analyses, the combination of both tests (synoptical incontinence score) could be confirmed as an independent predictor for UI after 12 months (p = 0.011). Conclusions: Readily accessible "everyday" diagnostics (pad test/change of pads after catheter removal) following RALP seem to be associated with a higher rate of long-term UI. This finding is crucial since patients with a potentially higher need for patient education and counselling can be identified using these readily accessible tests. This could lead to a higher patient satisfaction and improved outcomes.

Review of AI Based Career Counselling

In the domain of technology-driven educational advancements, artificial intelligence (AI) has become pivotal in enriching student experiences. This abstract gives into the rising need for effective career counseling and proposes the development for a specialized AI-based software application to address this need. Recognizing the universal role of technology in students’ lives, leveraging AI for personalized career guidance becomes necessity. The envisioned desktop application aims to redefine traditional career counseling methods by using AI algorithms' advanced capabilities. It seeks to provide personized recommendations to individuals or students navigating diverse career paths by evaluating academic performance, skills, and interests. Targeting three main user groups students, career counselors, and educational institutions the application offers a user-friendly interface for students to input details and preferences, resulting in a personalized career roadmap. Career counselors benefit from AI-generated analytics, entitle them to offer more informed guidance. This abstract covers the transformative potential of AI in enhancing career counseling services and facilitating informed career decisions

Correlation Between Medically Diagnosed Anxiety and Depression Disorder and Self-Reported Breast Implant Illness.

Anxiety disorders, both with and without comorbid depression, are widespread globally. In this study we investigate the intersection of anxiety, depression, and self-reported breast implant illness (BII) in females undergoing aesthetic breast surgery. The objective of our research was to enhance understanding about mental health history, psychotropic medication use, and its relation to BII symptoms. A cohort of 240 consecutive female patients undergoing elective breast surgery was studied. In the study we categorized patients by groups based on the presence of self-reported BII symptoms and the type of breast surgery performed. Mental health history, psychotropic medication use, and time spent in treatment for mental illness were scrutinized. Statistical analyses were conducted, including multiple regression analysis. Results revealed that patients with self-reported BII symptoms often had a preexisting anxiety/depression disorder treated medically before obtaining breast implants, and this disorder predicted the occurrence of BII symptoms. These patients tended to be diagnosed with anxiety and depression at a younger age, initiate medication therapy earlier, take more medications for their condition, and spend more time in therapy compared with others undergoing elective breast surgery. Implications of this study highlight the need for comprehensive counseling between plastic surgeons and patients with self-reported BII symptoms. Understanding the role of anxiety/depression in the pathogenesis of self-reported BII is crucial, and collaboration with psychiatrists and other mental health professionals can ensure improved supportive care. The findings contribute to a better understanding of the psychological aspects surrounding breast implant surgery and self-reported BII and emphasize the importance of preoperative mental health assessments in appropriate patient selection for elective breast surgery.

Well-being of the students – What matters?

Anxiety disorders are highly prevalent globally and it is much more prevalent among adolescents because of their exposure to a variety of stressors. Research shows that emotional and biopsychosocial well-being changes over the course of their schooling, with a general increase in anxiety, highlighting the need to further investigate the risk factors that contribute to worry and anxiety symptoms among college student populations. In Mauritius, there has been a rise in the number of adolescents who are recipients of psychiatric treatments at the local government hospitals as well as an increase in the number of cases reported to the school authorities. The present study aimed to identify the causal factors of anxiety among adolescents, and its effects in the educational context. Further, the role of educational social workers in overcoming anxiety was explored and the aim was achieved using the exploratory approach. A focus group discussion using a semi-structured questionnaire was conducted with ten (10) people including educational social workers and educational psychologists recruited through convenience sampling. A thematic analysis of the data shows academic anxiety as an emerging factor, followed by bullying and lastly, family issues. The findings revealed impacts at the school level such as students’ inability to concentrate in class, non-participative and also showing emotional distress. While educational social workers provide counselling to students and parents, a need for teacher empowerment and peer counselling are proposed as future avenues.

Risk Perception and the Genetic Testing Gap in Frontotemporal Degeneration (FTD): FTD Insights Survey Highlights the Need for Comprehensive Genetic Counseling (S28.009)

Risk Perception and the Genetic Testing Gap in Frontotemporal Degeneration (FTD): FTD Insights Survey Highlights the Need for Comprehensive Genetic Counseling (S28.009)

Understanding the Experiences and Counseling Needs of Black Women with Infertility

ABSTRACT The lack of acknowledging infertility in the Black community often leaves women bewildered about their situations and the availability and influence of counseling support. In addition to these perplexities, counseling scholars have not fully documented the intersectional experiences of Black women experiencing infertility challenges. Utilizing an intersectionality approach, this study makes meaning of the interpretations surrounding mental health and Black women experiencing infertility challenges. The data analysis of 13 interviews captures how Black women reflect on infertility experiences, narrate mental health and coping responses, and explain counseling needs and barriers. Findings from this study suggest that self-concept and internal understanding may draw upon historical racial contexts of femininity and reproductive value and the societal expectation to shoulder personal responsibility for challenges. This study provides counselors with ways to conceptualize this population through race, gender, and feminist theory while sharing strategies to guide clients toward healing gendered and race-related challenges.

Infantile Systemic Hyalinosis

Infantile systemic hyalinosis (ISH) is a rare autosomal recessive disorder characterized by widespread hyaline deposition in various tissues, resulting in multi-organ dysfunction. We present a case of a 6-month-old male child with minimal limb movements and skin lesions, emphasizing the diagnostic challenges and multidisciplinary approach involved in managing ISH. Medical history revealed intrauterine growth retardation and a neonatal intensive care unit admission, prompting referral to a tertiary care hospital. A comprehensive evaluation, including imaging, electrophysiological studies, and histology, confirmed the diagnosis of ISH-associated myopathy. Dermatological manifestations and genetic implications are discussed, highlighting the need for early recognition and genetic counseling. Our case contributes to the limited literature on ISH, emphasizing the importance of collaborative efforts in diagnosing and managing this complex disorder.

Factors associated with exclusive breastfeeding knowledge and practices in a tertiary hospital of Central India

Background: Breastfeeding is a behavioural act of the mother, one that is affected by demographic, socioeconomic, and faith factors as well as by cultural traditions and beliefs. However, there is little scientific literature on potential gaps between knowledge and standard practices regarding exclusive breastfeeding and its predictors among mothers in central India. Methods: A cross sectional study was conducted to explore the knowledge, perceptions, practices, and the associated factors of exclusive breastfeeding among urban and rural mothers at a tertiary hospital of central India. Results: A total of 500 post-natal mothers at the study hospital were interviewed to assess their knowledge and practices of exclusive breastfeeding. The study revealed that knowledge of exclusive breastfeeding was 47% while breastfeeding practices for up to six months of babies was reported by only 15% of participants. Breastfeeding within one hour of birth was reported by 31% of mothers. About 62% did not feed colostrum, while 57% fed their baby pre-lacteal feed. Mothers belonging to a rural community, living in joint family, literate, employed, better-off economic status, multigravida, having a previous history of vaginal delivery, and male child, and those counselled regarding breastfeeding during ANC visits had higher knowledge and better practices of exclusive breastfeeding. Conclusions: The findings of the study suggest an urgent need for regular counselling in ANC clinics to promote exclusive breastfeeding among women and their family caregivers. Breastfeeding awareness education programs for all pregnant women are recommended to ensure that mothers learn best practices regarding breastfeeding and its benefits.

Dagusibu And Pkrt Health Counseling In The Surrounding EnvironmentFor Wkri Dpd West Sumatra

Mothers need knowledge of the treatment and use of PKRT according to the rules. This is important considering that the mother is the individual responsible for taking care of the family's needs. The expert must welcome the fulfillment of these mothers' needs must be received through devotional activities. One form of service activity that mothers can do is health counselling which aims to measure the influence of counselling on changes in participants' attitudes. The participants in this counselling are the categorial group of WKRI DPD West Sumatra The method used is offline and online interactive counselling. The supporting media used are Microsoft PowerPoint, Quiziz, and Zoom. The data collection method used is pretest-posttest. The results obtained in the counseling activity were a change in participants' attitudes before and after counseling with a signification value of p&lt;0.05. It means that there is a need for interactive counseling on drugs and PKRT that can help improve public health and lower long-term adverse risks.

From Conception to Revelation: Non-Invasive Prenatal Testing Explored

Prenatal testing plays a crucial role in addressing the inherent unpredictability of genetic disorders that can affect unborn children. Non-Invasive Prenatal Testing (NIPT) has emerged as a groundbreaking tool in the realm of prenatal care, enabling the early detection of chromosomal abnormalities. By examining fetal DNA present in the mother's bloodstream, NIPT has achieved remarkable accuracy rates, surpassing invasive techniques that carry inherent risks. However, with these advancements come ethical considerations. The results of NIPT can significantly influence a mother's decision regarding the continuation or termination of pregnancy. This decision can be further complicated by religious beliefs, which often play a pivotal role in guiding choices related to pregnancy. Moreover, receiving a positive result from NIPT can subject expectant mothers to profound emotional stress, highlighting the need for comprehensive counseling and support services. In addition to these ethical concerns, practical limitations persist. The cost of NIPT remains a substantial barrier for many families, potentially limiting its accessibility. Furthermore, NIPT's accuracy can be influenced by factors such as gestational age, with tests often yielding inconclusive results when fetal fractions are low. Despite these challenges, technological innovations, including microarrays and Next Generation Sequencing (NGS), have bolstered the capabilities of NIPT. These advancements enable a more comprehensive assessment of fetal DNA, enhancing the overall quality of prenatal care. As NIPT continues to evolve and integrate with broader genomic technologies, society must engage in thoughtful reflection on its implications. The potential normalization of pregnancy terminations based on genetic information underscores the importance of ethical and societal discussions surrounding the use of NIPT, with a focus on preserving informed patient choices and ensuring comprehensive support for expectant parents facing difficult decisions.

IMPACT OF THE WAR IN THE BETWEEN RUSSIA AND UKRAINE 2014-2024 PERIOD ON THE MENTAL AND EMOTIONAL STATE OF STUDENTS

The military conflict in Ukraine became a serious test for our country and its population, marking the beginning in 2014 after the annexation of Crimea by Russia and the events in the east of Ukraine. Donetsk and Luhansk became centers of armed conflicts with illegal armed formations.&#x0D; In 2022, the situation only worsened, when the aggressor country launched a full-scale invasion of Ukraine, deepening the humanitarian crisis and increasing the scale of the disaster.&#x0D; The duration of this military conflict is already almost 10 years, during this period it led to significant human losses, covering both the civilian population and military personnel. Many people were forced to leave their homes and become internally displaced persons of their own country.&#x0D; War not only has material losses and physical consequences, but also seriously affects the mental health of a nation. After two years of martial law, the deterioration of the mental state of the entire population is noticeable. War events cause stress reactions and trauma that persist long after hostilities have ceased.&#x0D; Everything said earlier indicates that it is necessary not only to restore destroyed houses and infrastructure, but what is especially important is to develop a methodology and create a system of psychological and psychiatric support for people who suffered from the military conflict. The need for rehabilitation programs and counseling becomes an important step in ensuring further recovery and strengthening of the nation's mental health [3].

Patients' perspectives about the role of primary healthcare providers in long-term opioid therapy: a qualitative study in Dutch primary care.

Over the past decade, long-term use of prescription opioids for chronic non-cancer pain has risen globally despite the associated risks. Most opioid users receive their first prescription in primary care. To investigate the perspective of patients who are long-term opioid users in primary care regarding the role of healthcare providers (HCPs) in their prolonged opioid use. Semi-structured interviews in Dutch primary care. We recruited patients who were long-term users of opioids for chronic non-cancer pain from seven community pharmacies in the Netherlands. In-depth, semi-structured interviews focused on patients' experiences with long-term opioid use, access to opioids, and the guidance of their HCPs (primarily their GPs and pharmacists). A directed content analysis was conducted on the transcribed interviews using NVivo. Participants (n = 25) described ways in which HCPs impacted their long-term use of opioids. These encompassed the initiation of treatment, chronic use of opioids, and discontinuation of treatment. Participants stressed the need for risk counselling during initial prescribing, ongoing medication evaluations including tapering conversations, and more support from their HCP during a tapering attempt. Patients' perspectives illustrate the important role of HCPs across the spectrum of opioid use - from initiation to tapering. The results of this study underscore the importance of clear risk counselling starting at initial prescribing, repeated medication assessments throughout treatment, addressing tapering at regular intervals, and strong support during tapering. These insights carry significant implications for clinical practice, emphasising the importance of informed and patient-centred care when it comes to opioid use for chronic non-cancer pain management.

(147) Analysis of Sexual Dysfunction Development among Male and Female Living Kidney Donors

Abstract Introduction The need for kidney donations in patients with end-stage kidney disease has continued to exceed the number of deceased donor transplants, signifying the need for the continued growth, sustainability, and success of living kidney donation. Following donation, living kidney donors have excellent survival rates with mixed data regarding long-term outcomes of renal failure, hypertension, and proteinuria. However, no studies to our knowledge have looked at differences in the development of long-term sexual dysfunction following living kidney donation, a potentially serious quality of life issue. Objective To analyze differences in five-year sexual dysfunction outcomes among male and female living kidney donors using the US Collaborative Network within the TriNetX database, a federated network of EMR data from multiple healthcare organizations across the United States. Methods We used the TriNetX database to perform a propensity score-matched cohort study comparing five-year outcomes of sexual dysfunction development among adult (≥18) male living kidney donors (Male) and female living kidney donors (Female) from December 2013 to December 2022. Living kidney donors were defined as the presence of one diagnostic code and one procedural code. Patients were excluded from the study if they had any instance of diagnosed transplant status (by ICD-10) or transplantation procedures (by CPT) prior to the kidney donor status. Patients were matched on age, sex, race, ethnicity, marital status, diabetes mellitus, cardiovascular disease, personal history of genitourinary disease, presence of urogenital implants, mood disorders, BMI, tobacco and alcohol use, and problems related to lifestyle and socioeconomic circumstances. Primary outcomes analysis included 5-year hazard ratio of diagnosed decreased libido, sexual dysfunction (composite of new diagnosed male ED, vaginismus/dyspareunia, infertility, orgasmic disorders, arousal/desire disorders, or unspecified), UTI, and STDs. Secondary outcomes included sex counseling or problems in relationship with spouse or partner. Results There were 2,821 patients in each cohort after matching (Male, Female). Mean age of the cohort was 42.7 ± 12.7, 73.3% were White, and 10.8% were Hispanic/Latino (p &amp;gt;0.05). At 5-years, Kaplan-Meier analysis revealed that the Male donor cohort had a significantly higher hazard ratio (HR) than Female donors for sexual dysfunction (HR: 3.006, 95% Confidence Interval [CI]: 1.761,5.131). Between the cohorts, 39 (1%) Male patients developed ED and ~10 (&amp;lt;1%) Female patients developed vaginismus/dyspareunia within 5 years. No significant difference was found for the development of sexual arousal disorders/desire disorders (0.17% vs 0.06%, p = 0.052), orgasmic disorders (0.03% vs 0.03%, p = 0.99), decreased libido (0.48% vs 0.85%, p =0.94) and STD’s (0.72% vs 0.89%, p = 0.70). For secondary outcomes, no significant difference was found for the 5-year hazard of need for sex counseling or interpersonal relationship issues. Conclusions In our analysis of this large, real-world database, we found that male living kidney donors had higher rates of sexual dysfunction development 5-years post-living kidney donation. While living kidney donation is a safe, viable, and excellent alternative to deceased kidney donation, clinicians and living donors should both be aware about the potential association of developing sexual dysfunction post-donation. Disclosure No.

Stability of End-of-Life Care Wishes and Gender-Specific Characteristics of Outpatients with Advanced Cancer under Palliative Therapy: A Prospective Observational Study

Introduction: Early integration of palliative care and advance care planning (ACP) play an increasingly important role in the treatment of patients with advanced cancer. Advance directives (ADs) and patients’ preferences regarding end-of-life (EoL) care are important aspects of ACP. In the outpatient setting, the prevalence of those documents and EoL care wishes is not well investigated, and changes in the longitudinal course are poorly understood. Methods: From June 2020 to August 2022, 67 outpatients with advanced solid tumors undergoing palliative cancer therapy were interviewed on the topic of ACP in a longitudinal course. From this database, the prevalence of ADs, healthcare proxy, EoL care wishes, and the need for counseling regarding these issues were collected. In addition, EoL care wishes were examined for their stability. Results: Fifty-one patients (76.1%) reported having ADs, and 41 patients (61.2%) reported having a healthcare proxy. Nineteen patients (37.3%) with ADs and 11 patients (68.7%) without ADs indicated a wish for counseling. Reported EoL care wishes remained stable over a period of approximately 6 months. Nevertheless, intraindividual changes occurred over time within the different EoL care preferences. The desire for resuscitation and dialysis were significantly higher in men than in women (resuscitation: 15 of 21 men [71.4%] versus 9 of 22 women [40.9%], odds ratio [OR] 3.611, 95% confidence interval [CI], 1.01–12.89, p = 0.048; dialysis: 16 of the 23 men [69.6%] versus 9 of the 25 women [36.0%], OR: 4.063, 95% CI: 1.22–13.58, p = 0.023). Conclusion: Our results show a reasonably high percentage of ADs and healthcare proxies in our study cohort. The observed stability of EoL requests encourages the implementation of structured queries for ADs and healthcare proxy for outpatients undergoing palliative treatment. Our data suggest that gender-specific characteristics should be further investigated in this context.

Initial assessment of the psycho-emotional state of patients with temporomandibular disorders: A pilot study.

Temporomandibular disorders (TMD) are a group of conditions that affect the function of the masticatory muscles, temporomandibular joints and surrounding structures. The objective of the preliminary investigation was to develop an initial questionnaire for emotional assessment, pre-designed for TMD patients, and provide guidance for further management through referral to psychological and/or psychiatric counseling. Additionally, we aimed to compare the results of tests carried out in TMD patients with those of healthy subjects. The study involved 260 patients who reported for dental treatment. The TMD study group (Group 1, n = 130) consisted of patients diagnosed with TMD, and the control group (Group 2, n = 130) had TMD diagnostically excluded. The questionnaire included 30 questions about the emotional state of the patients in the past 4 weeks. The mean scores were 37.715 points for Group 1 (median (Me) = 35.5, standard deviation (SD) = 12.58 and 24.938 points for Group 2 (Me = 24, SD = 7.95) (p < 0.001). The research suggests that the developed questionnaire is useful for an initial assessment of the psycho-emotional state of TMD patients. Furthermore, the results emphasize a greater need for psychological counseling in TMD patients compared to their healthy counterparts.