BackgroundIt has been suggested that developmental coordination disorder (DCD) could be caused by a ‘dysconnection’ in brain and skeletal muscle communication. To date no previous work has examined the integrity of this neuromuscular process in individuals with DCD. AimsTo conduct a feasibility study for measuring functional connectivity of the brain and muscle in an individual with DCD using corticomuscular coherence (CMC). Methods and ProceduresAn individual with DCD and a typically developing (TD) participant completed a series of sustained 5-second voluntary isometric hand contractions (15 ± 5 % MVC) on a handheld dynamometer under both single and dual task (i.e., counting backwards) conditions. EEG, EMG and force data were collected. Outcomes and ResultsThe participant with DCD displayed poorer force steadiness and higher mental demand compared to the TD participant and in dual task conditions. The TD participant displayed a commonly observed pattern of CMC that was highly localised over the contralateral hand area, the DCD participant displayed a less localised CMC across cortical regions. Conclusions and ImplicationsThese findings support the feasibility of measuring CMC in DCD populations and offer some, albeit preliminary, evidence of impaired communication between the brain and muscles in these individuals.