To examine the impact of monovision on dynamic changes in accommodation, pupil responses, spherical aberration and resultant image quality in early presbyopes. Refractive state, pupil size and spherical aberration levels were monitored in nine early presbyopes who exhibited some accommodation (40-50years, mean=42±2.37years) using a Shack-Hartmann aberrometer as a binocularly viewed stimulus stepped closer (from 2m to 40cm), or farther (from 40cm to 2m). Comparison data from two fully presbyopic (i.e. non-accommodating) subjects (ages 46 and 61years) and two young adults (ages 26 and 29years) were also collected. Each subject was fit with four different refractive strategies: (1) both eyes corrected for 2m, (2) both eyes corrected for 40cm, (3) monovision with the measured right eye corrected for 2m and, (4) monovision with the right eye corrected for 40cm. Monochromatic image quality was quantified using the AreaMTF metric. When fit with monovision, the largest number of early presbyopes produce an accommodative response dominated by the right eye correction (distance or near) as the stimulus is abruptly changed from the retinal conjugate plane of one eye to that of the other eye. However, the accommodative responses in some early presbyopes were always dominated by the distance corrected eye, the near corrected eye, or by convergence. When the stimulus approached, the near corrected eye experienced high image quality only if there was no accommodative response. However, reduced image quality was observed if an accommodative response was initiated. Neither accommodation nor pupil response latencies were longer with monovision corrections compared with bilateral distance corrections (p>0.05). In the early presbyopes, spherical aberration was reduced during near viewing, but primarily due to pupil miosis and not lens shape changes. As the stimulus was abruptly changed from the retinal conjugate plane of the distance corrected eye to that of the near corrected eye, most early presbyopes fit with monovision accommodated, which resulted in a decline, not an increase in image quality in the near corrected eye. These results reveal a non-optimal accommodative strategy in early presbyopes fit with monovision.