Measurements of the (p, n) continuum spectra for targets of /sup 103/Rh, /sup 104/,/sup 105/,/sup 106/,/sup 108/,/sup 110/Pd and /sup 107/,/sup 109/Ag at proton energies of 18, 22, and 25 MeV are compared with the predictions of the hybrid model for pre-equilibrium reactions. The systematics of the odd-even differences in spectral shape are found to be much clearer than in a previous measurement at lower energy with targets near a closed shell. Most of the variation in spectral shape between even- and odd-A targets is attributed to energy shifts produced by pairing effects. Comparisons between the various even-A or odd-A targets show little change in shape and magnitude of the highest energy portion of the measured (p, n) spectra over this range in A; this is consistent with the predictions of the model. The density of one-proton one-neutron-hole states at low excitations is calculated from a single-particle basis; the calculated values show more structure than is implied by the data, but do have the correct energy dependence when averaged over a wide enough interval. (AIP)