Correct Copy Research Articles

Towards gene therapy for haemophilia B using primary human keratinocytes

Haemophilia B might be permanently cured by gene therapy--the introduction of a correct copy of the factor IX gene into the somatic cells of a patient. Here, we have introduced a recombinant human factor IX cDNA into primary human keratinocytes by means of a defective retroviral vector. In tissue culture, transduced keratinocytes were found to secrete biologically active factor IX and after transplantation of these cells into nude mice, human factor IX was detected in the bloodstream in small quantities for one week. This is the first demonstration of a therapeutic protein reaching the bloodstream from transduced primary keratinocytes. This may have implications for the treatment of haemophilia B and other disorders.

The Education of Henry Adams: "Music for Ourselves Alone"

N February 1908, one year following the private printing of The Education of Henry Adams, Adams wrote to his friend Worthington Chauncey Ford, who had requested copy, that the book was meant for novel-a story with purpose-quite unlike biography. Unfortunately, he complained, my material too slight and too labored. We live in too thin an atmosphere. In comparison to his previous book, Mont-Saint-Michel and Chartres, privately printed in 1904, The Education was a rotten failure. Adams requested, as he did of all those to whom he sent the work, that Ford return corrected copy with suggestions on how to improve it. He lamented the absence to date of any substantive responses. When I think how everyone in old days, from Kepler to Galileo, to Darwin and Huxley, relied on correspondence and private discussion for nine tenths of their work, I am literally dumfounded [sic] to see how helpless an American to obtain light from any living source whatever. The Education as it stands, he concluded, is intended as private letter, inviting discussion. It has no other value. For the public it must take different form.'' This unpublished letter richly suggestive one, espe-

ERRATA

Please note the following errata in the 1982 Red Book, and correct your copy: Page 188. The 8th line under "Treatment" should read "not to exceed 4 gm per day" NOT "not to exceed 4 mg per day."

ERRATA

Please note the following errata in the 1982 Red Book, and correct your copy: Page 277. Lines 7-9 are duplications. Cross them out.

Increasing the Protection of Newborn Infants in Cars

Please note the following errata in the 1982 Red Book, and correct your copy: Pages 26-27. The bottom line of page 26 and the top two lines of page 27 are duplications. Cross them out.

C&ENL: a progress report

This page and some of the other pages in this issue of Chemical & Engineering News have been produced using the magazine's new electronic copy handling and typesetting system. With this approach copy is written, edited, hyphenated and justified, and accurately sized on video display terminals at the magazine's Washington, D.C., headquarters. The final, corrected copy then is transmitted via telephone lines to the printer—Mack Printing Co. in Easton, Pa.— where it is set automatically in type on a photocomposition device. The system is in the shakedown phase. It soon will be extended to essentially all staff members, including those in C&EN's news bureaus in New York, Chicago, Houston, and San Francisco. When fully operational it will streamline the magazine's editorial operations greatly—saving time and money, allowing for later release of copy, and eliminating some potentially error-producing steps. For the first time, copy from the inception of a story to the final printed page will ...

Erratum

The Editors of the American Zoologist wish to call to your attention an error that appeared in Volume 21 number 2. In the paper entitled “Teratology and Early Fish Development,” pages 517–533, the name of a coauthor was mistakenly inserted by the editorial staff. The authorship belongs solely to Dr. Hans W. Laale, University of Manitoba, Winnipeg, Manitoba, Canada. A corrected copy of the first page of the article is enclosed. Dr. Laale's name should also appear alone in the Table of Contents and the Running Heads. We apologize for any inconvenience this error may have caused Dr. Laale and the scientific community.

American States, Churches, and Slavery. By J. R. Balme, Pictures of Slavery in Church and State; Including Personal Reminiscences, Biographical Sketches, Anecdotes, Etc. Etc. By John Dixon Long, The London Missionary Society's Report of the Proceedings Against the Late Rev. J. Smith, of Demerara, Minister of the Gospel, Who Was Tried Under Martial Law, and Condemned to Death, on a

American States, Churches, and Slavery. By J. R. Balme, Pictures of Slavery in Church and State; Including Personal Reminiscences, Biographical Sketches, Anecdotes, Etc. Etc. By John Dixon Long, The London Missionary Society's Report of the Proceedings Against the Late Rev. J. Smith, of Demerara, Minister of the Gospel, Who Was Tried Under Martial Law, and Condemned to Death, on a

An Attic Inscription of the Archidamian War

These three numbers in the Corpus are parts of one inscription, which evidently contains the expenditure of Athena's Treasurers for some portion of the years 432/1–427/6. 294 is in two pieces, of which fragment a had not apparently been seen since Lolling's time, and I.G. I2. gives it from Lolling's not quite correct copy: Bannier had observed with great acuteness from the published copies that fragments a and b of 294 join.

The Decipherment of the Moscho-Hittite Inscriptions

The number of Hittite hieroglyphic inscriptions known to us has increased considerably of late years. Unfortunately a large proportion of the texts is either broken or illegible, not infrequently just where a complete text is most needed. Thanks, however, to our increased knowledge, it is now possible to correct former copies and supply in many caṡes missing characters or words. The result is that I can now improve to a large extent upon my old attempts at translation as well as correct mistakes and misreadings. Another result is to show that the fundamental elements in my decipherment are correct; it is true that I have made many mistakes, as is inevitable in pioneering work of the kind, but on the whole it was based on sound principles and a considerable proportion of the phonetic values or ideographic meanings I have attached to the characters turn out to be right. Those who wish to see the evidence for these will find it given in detail in my articles in the Proceedings of the Society of Biblical Archœology. In my present notes I shall give it only where the identifications are either new or corrections of those I formerly proposed.

The Worship of the Patriarch Lot in Palestine

IN the American Journal of Archaeology for December last, ~fr. 'Villard H. Robinson, Jr., has published two Greek inscriptions from Palestine referring to the Holy Lot, and in one case to intercessions being made to him as to a saint. The first of these was found in the floor of a church, accompanied by a mosaic, near to Mount Nebo, and in the neighbourhood of nladaba, where the famous ~1osaic n1ap of Palestine and the Egyptian Delta, ,vas discovered some years ago. This text wa~ edited from copies by Pere F. M.Abel, in the ReVlte Bibliqlle, in 1914; but some of the lines were rnisplaced and other minor errors made in the copies of the learned father. ~lr. Robinson's more correct copy is therefore probably final, and we here give it together with his translation :-

To make an absolutely correct camera copy of a chart by means of a single distorting lens

To make an absolutely correct camera copy of a chart by means of a single distorting lens

On the Geology of some parts of the Alpine and Mediterranean regions of South-Eastern Europe

Dr. Boué in this communication states his views in reference to the classification of the nummulitic rocks and the connected strata in various places round the shores of the Mediterranean. He points out especially the great extent of these deposits in European Turkey, as shown in a corrected copy of his Geological Map of that country which he has forwarded to the Society. In this map he also indicates the occurrence of Silurian formations in Carinthia, Styria, and some of the neighbouring regions.

XI.—Notices on the Geology of the North Coast of the Counties of Mayo and Sligo in Ireland.

The country I propose to describe, comprises the northern districts of Mayo and Sligo. In constructing the map*, I have used for the former county, the excellent map of Mr. Bald, some fishery charts by Nimmo, and some local surveys; and for Sligo, a corrected copy of Larkin’s Map. In connecting the two counties, I have used triangles resulting from the operations of the Ordnance Survey, most liberally communicated by Captain Portlock, with the permission of Colonel Colby; and where doubts and deficiencies in the details occurred, observations were made with a three-inch sextant, or Kater’s Compass. The drawings (pp. 158. 162. 165. 167.) are from sketches taken on the spot, with every determination to sacrifice picturesque effect to accuracy. The only notice which has been published respecting this part of Con-naught, is a short but very able and accurate sketch in Mr. Griffith’s paper on its Bogs, attached to the 4th Report of the Commissioners. The Ox mountain ridge extends through the district from south-west to north-east. It is chiefly formed of mica slate, hornblende slate, gneiss, and quartz rock, the strata dipping rapidly to the south. At the base occurs a conglomerate, alternating with sandstone and slate clay; and overlaid by the carboniferous limestone, which extends westward from Sligo to the Nefin group. This group is the commencement of the primary tract, reaching northward and westward to the ocean. The section from Lough Talt to Downpatrick Head, displays the succession of strata†. The Ox Mountains have a mean

XIII. Account of the remarkable Case of Margaret Lyall, who continued in a State of Sleep nearly Six Weeks

My Dear Brother,The inclosed account was drawn up at the request of Robert Græme, Esq. when all the circumstances were fresh in my own recollection, and that of all with whom I had occasion to confer on the subject. Since you requested me to send you a correct copy of the whole case, I have renewed my inquiries among the friends of the young woman, and submitted my account to several persons, who were most capable of supplying any omissions, or correcting any mistakes. I can confidently vouch for the general accuracy of the statement; but would not wish its credibility to rest entirely on my single testimony.