Muslim men and women are required to study the corpus of knowledge known as women's blood education, which includes the science of menstruation, childbirth, and istihadah, as well as the related laws. This is due to the fact that the knowledge of women's blood is one of the sub-discussions under the chapter on worship, which contains laws pertaining to the fundamentals of Islam, such as prayer, fasting, and Hajj. At the secondary education level, this topic is introduced to 13-year-old Form 1 students through Form 1 science classes that include a subtopic on the menstrual cycle. The content analysis revealed, however, that there is a significant difference between the menstrual cycle learning content included in the Standard Document for Curriculum and Assessment (DSKP) of Form 1 science subjects and the discussion of the menstrual cycle from the perspective of jurisprudence, which has implications from the standpoint of legal determination. Therefore, the purpose of this article is to compare the discussion of menstrual blood written in the Standard Document for Curriculum and Assessment DSKP of Science KSSM Form 1 in Malaysia with the discussion of menstruation from a jurisprudential perspective in order to provide students with a correct understanding and prevent the existence of misunderstandings in determining the status of menstrual blood and istihadah in their subsequent learning. This research employs the comparative method to analyse multiple documents pertaining to the disciplines of science and fiqh. Analysed documents included the Standard Document for Curriculum and Assessment DSKP for Science subjects in the Malaysian Secondary School Standard Curriculum (KSSM), the Malaysian KSSM Form 1 Science textbook, the Syafi'i school of law, articles, and scientific studies. According to the results of the analysis, there are three differences in the input about menstrual blood that is placed in the textbook of Science subjects Form 1 with the discussion of menstruation from the perspective of the law, namely the age of puberty, the age of menopause, and the menstrual cycle. The differences in the input of menstruation learning content necessitate a clear understanding and comprehension of this subject specifically in the subject of Islamic Education under the subtopic of worship. Therefore, cooperation from all parties, including instructors, the administration, and the government, is crucial so that all students can learn about women's blood in school, thereby enabling them to worship with greater assurance.