Event Abstract Back to Event Aphasia due to local infarction of the corpus callosum after thalamus hemorrhage Qing Yang1, Yue Cao1, Ying Chen1, Tingwei Wang1, Zuojun Cao1, Ruiping Hu1, Junfa Wu1 and Yi Wu1* 1 Huashan Hospital, Fudan University, China Aphasia is a rare manifestation of local corpus callosum lesion. Here we present a case of a 58-year-old right-handed male patient, who first suffered a hemorrhagic stroke in the right thalamus, followed by a corpus callosum ischemic stroke about one week later. As the patient’s care-giver reported, in the first week after his hemorrhagic stroke, the patient’s language abilities were only mildly impaired. However, both his speech and writing abilities dropped dramatically one week later, and MRI scanning revealed acute infarction and lesion in the left genu and body of the corpus callosum. The patient was admitted to our department for further rehabilitation one month after his initial onset of hemorrhagic stroke. He still lacked any type of language expression at this point, but he was able to understand and follow simple oral instructions, such as “stretch out your hand”. His language skills were formally assessed by the Chinese version of Western Aphasia Battery, and the results indicated “global aphasia”, as he score only 2.5 for the listening comprehension subtest, and scored zero for all other subtests. In addition to aphasia, the patient also suffered unilateral neglect and severe left hemiplegia. After one month of speech therapy, the patient’s listening comprehension improved significantly. Although his oral expression also improved, it remained nonfluent, agrammatic, and telegraphic. This is a rare case of aphasia due to local left corpus callosum lesion, with a subacute right thalamus stroke. The pattern of the patient’s aphasia is similar to two aphasia cases previously reported (Ishizaki et al., 2012; Saba & Blum, 2014), both due to right corpus callosum infarction. However, the degree of the patient’s language deficits was more severe in our case. This may be due to the preceding thalamus hemorrhage, or because the patient’s corpus callosum lesion was bigger and located in the dominant hemisphere. References Ishizaki, M., Ueyama, H., Nishida, Y., Imamura, S., Hirano, T., & Uchino, M. (2012). Crossed aphasia following an infarction in the right corpus callosum. Clin Neurol Neurosurg, 114(2), 161-165. doi: 10.1016/j.clineuro.2011.09.009 Saba, S., & Blum, S. (2014). Aphasia due to isolated infarction of the corpus callosum. BMJ Case Rep, 12, pii: bcr2014204316. Keywords: unilateral neglect, case, Stroke, Corpus Callosum, Aphasia after stroke Conference: Academy of Aphasia 57th Annual Meeting, Macau, Macao, SAR China, 27 Oct - 29 Oct, 2019. Presentation Type: Poster presentation Topic: Not eligible for student award Citation: Yang Q, Cao Y, Chen Y, Wang T, Cao Z, Hu R, Wu J and Wu Y (2019). Aphasia due to local infarction of the corpus callosum after thalamus hemorrhage. Front. Hum. Neurosci. Conference Abstract: Academy of Aphasia 57th Annual Meeting. doi: 10.3389/conf.fnhum.2019.01.00080 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 06 May 2019; Published Online: 09 Oct 2019. * Correspondence: Prof. Yi Wu, Huashan Hospital, Fudan University, Shanghai, China, wuyi@fudan.edu.cn Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Qing Yang Yue Cao Ying Chen Tingwei Wang Zuojun Cao Ruiping Hu Junfa Wu Yi Wu Google Qing Yang Yue Cao Ying Chen Tingwei Wang Zuojun Cao Ruiping Hu Junfa Wu Yi Wu Google Scholar Qing Yang Yue Cao Ying Chen Tingwei Wang Zuojun Cao Ruiping Hu Junfa Wu Yi Wu PubMed Qing Yang Yue Cao Ying Chen Tingwei Wang Zuojun Cao Ruiping Hu Junfa Wu Yi Wu Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.