In the midst of a major corporate reorganization and an ever‐changing industry landscape, how does a corporate real estateorganization successfully build enterprise alliances and create integrated approaches to problem solving in order to 1) realign the real estate portfolio and 2) achieve optimal real estate portfolio efficiencies? The answer lies in the use of enterprise program management approaches to identify stakeholders and to invest in lifecycle management. This case study will examine how Sprint Enterprise Property Services successfully adopted the use of enterprise program management principles in order to achieve significant gains in process improvements, to transform a traditional work environment, and to institute a dynamic long‐term vacancy reduction plan for the corporate real estate portfolio.