Background/Aim: There are no studies examining quality of life, anxiety levels, physical activities, and Covid-19 fear levels in people with cancer. The aim of this study was to examine physical activity status, coronavirus fear levels, and quality of life in oncological individuals during the COVID-19 pandemic. Methods: This study was conducted among oncology patients. The level of physical activity was assessed using the Rapid Assessment of Physical Activity Scale (RAPA 1), the level of fear with the Fear of COVID-19 Scale (FCV-19S), and the quality of life with the COVID-19 Impact on Quality of Life Scale (COV19-QoLTR). Results: The study was completed by 78 patients. Thirty-eight patients tested positive for COVID-19. Patients who tested positive for COVID-19 had significantly higher FCV-19S and COV19-QoL scores and lower scores of RAPA 1 (P<0.001). Also, FCV-19S was positively correlated with COV19-QoLTR and negatively correlated with RAPA 1 scores (P<0.001). Conclusions: These findings suggest the need for more clarity and tailoring of physical activity-related advice for oncology patients with COVID-19 and improved support to resume activities important to individual well-being.