Background: Poultry production quality could be adjusted or improved through the introduction of local plant resources into the diet. The current study evaluated the effects of total corn substitution with triticale and bentonite supplementation on broiler performance, carcass meat characteristics and blood profiles. Methods: Ninety one-day old broiler Cobb 500 chicks were allocated in a completely randomized experimental design, with three dietary treatments totaling 30 birds per treatment. The treatments contained either corn as a control group (BD), triticale (TRT) as a sole grain source, or triticale + 2% bentonite (TRT2%). The diets were provided from 14 to 47 days of age. Growth performance, carcass and breast meat quality and serum components were measured. Result: The chicks fed a triticale-based diet (TRT2%) had a higher final body weight and weight gain (P less than 0.05), while the FCR increased in the birds fed a triticale-bentonite-based diet (TRT2%). The data obtained indicated that total replacement of triticale for corn and dietary supplementation with bentonite resulted in better growth performance and an increase in breast yield (P less than 0.05). Moreover, the dietary supplementation of bentonite and triticale had a significant influence (P less than 0.05) on the serum levels of triglycerides and calcium. The chicks fed a basal diet had significantly (P less than 0.05) higher triglycerides and lower calcium blood serum levels than those fed experimental diets. However, there was no significant effect on breast meat traits (P greater than 0.05).