Coriander Fruit Research Articles

Simulation of the process of cryogenic freezing of coriander seeds

In the technology for extracting the required components from plant raw materials, in most cases, the grinding process is used as a preparatory operation before the main process, followed by the separation of the extracted material into target components.In most cases, as a result of such a process, we can talk about the effective extraction of only a single target component, while others inevitably lose their qualitative and quantitative indicators, which is due to the morphology of the plant raw material.One of the promising directions in the processes of destruction of plant material for further operations is selective disintegration. For this purpose optimal process conditions have been selected, such as heating, freezing and others. Raw materials obtained as a result of selective destruction can be effectively fractionated according to morphological and physicochemical characteristics, and only after that can be sent to subsequent operations with the greatest efficiency.Under modern conditions, the loss of essential oil in coriander associated with splitting the fruit reaches 23.4% of the oil weight in whole fruits. At the same time, the essential oil from split fruits is enriched with valuable components – linalool, geraniol, geranyl acetate and, in addition, contains less hydrocarbons and camphor. As shown in [1], oil from split fruits can be used to adjust the composition of batches of coriander essential oil in order to increase the content of linalool while simultaneously reducing the content of undesirable components – hydrocarbons and camphor, and can also be used primarily to isolate valuable components – linalool, geraniol. To reduce losses associated with splitting coriander fruits, it has been proposed to carry out mathematical modeling of the process of cryogenic freezing with subsequent grinding of the frozen mass, which will significantly reduce losses of essential oil. Considering that essential oils extracted from coriander show high antibacterial, antioxidant and antifungal activity [2], increasing the yield of high-quality coriander essential oil will allow its wider use in flavoring and food preservation, as well as for medicinal purposes, which is important and actual task.

Coriander response to nitrogen fertilizer sources in different competing levels of weeds

The competition of weeds with crops and nutrient management has a significant effect on the yield and economic efficiency of a country. This study aimed to evaluate the impacts of sulfur-coated urea and common urea on the yield and fatty acid composition of three coriander genotypes (Nahavandi, Pishgam, Ethiopia) under weeded and unweeded conditions. Traits including 1000 seeds weight, fruit yield, content of oil, and composition of fatty acids were examined. Nitrogen fertilizer and weeding treatments significantly improved the weight of 1000 seeds and weeds decreased the yield of fruit. The highest fruit yield was obtained by the Ethiopia genotype in weed-free conditions. Results showed that N fertilizer increased the oil percentage of coriander fruit. Urea fertilizer resulted in the highest oil content in the Nahavandi and Pishgam genotypes under weeded plots in the first and second years, respectively. Also, petroselinic, linoleic, and palmitic acids were the major coriander fatty acid composition. Nahavandi genotype showed the highest palmitic acid. Also, urea in the weed condition led to increase the linoleic acid content in the Nahavandi genotype. Overall, results showed that N fertilizer, especially urea, improved the quality characteristics of coriander fruits.

Modulatory role of Coriandrum sativum (coriander) extract against diabetic complications on the gonads of female rats and their offspring

It is well known that diabetes is associated with impairment of ovarian and testicular structure and function. Coriander (Coriandrum sativum L.) is identified as one of the oldest herbal plants valued for its nutritional and medicinal properties. This work is mainly designed to evaluate the possible modulatory role of dry coriander fruit extract against gonadal impairments associated with diabetes in female rats and their pups. Twenty-four pregnant rats were divided into four groups (n = 6): group I served as control, group II was administered daily with coriander fruit extract (250 mg/kg b.wt), group III was injected interaperitoneally with a single dose of streptozotocin (STZ) (80 mg/kg b.wt), and group IV was injected with single dose of STZ and post administered coriander extract. The experiment was conducted from the 4th day of gestation till the end of weaning. At the end of the experiment, the mothers’ rats and their offspring were weighed, sacrificed, the ovaries from mothers as well as ovaries and testes from offspring were immediately excised, and processed for histological, immunohistochemical and evaluation of apoptosis and transforming growth factorβ (TGF-β). Also, blood samples were collected and analyzed to estimate the levels of sex hormones as well as antioxidants.In STZ induced diabetes in mother's rats and their offspring, the ovarian sections revealed severe histopathological signs included several atretic follicles, dilated and congested blood capillaries. Additionally, the testicular sections of offspring appeared with destructive seminiferous tubules. Immunohistochemically, the ovarian sections displayed weak to negative expression for calretinin marker however the testicular sections showed strong expression for Bax protein (apoptotic marker) and weak to negative expression for Ki67 protein (proliferative marker). Also, the mean % values of positively expressed cells for TGF-β and annexin-v markers (late and early apoptosis indicator) were significantly elevated in the ovarian and testicular tissues of STZ-induced group of mother's rats and their pups if compared with control. Further results revealed that the levels of insulin, FSH, LH, estrogen, SOD and CAT were significantly decreased if compared with control however the levels of MDA and NO were significantly elevated. Administration of coriander fruit extract to diabetic rats successfully alleviated most of the altered histological, immunohistochemical, biochemical, and apoptotic changes induced by diabetes. Coriandrum sativum fruit extract has a powerful ameliorative role against STZ-induced diabetic gonadal dysfunctions in female rats and their offspring.

Phenolic constitutents, antioxidant and repellent activities of coriander (Coriandrum sativum L.) fruits using different solvent extracts

ABSTRACT The organic solvent extracts (hexane, chloroform, acetone, methanol and water) of coriander fruits were reported for their antioxidant and repellent activities. The methanol and acetone extracts revealed the highest antiradical activity as compared to the other solvent extracts. HPLC analysis revealed that phenolic acids were the major compounds in chloroform and acetone extracts, whereas flavonoids in methanol and water extracts. The methanol extract of coriander fruits exhibited the highest repellent effect against coleopteran insects. Additionally, the hexane extract of coriander fruits also exhibited potent repellent and toxic activities against rice weevil. It appeared that coriander fruit extract obtained with the apolar solvent had more repellent potential against Sitophilus oryzae as compared to Tribolium castaneum. For Lasioderma serricorne, the methanol extract of coriander fruits reduced in a very significant way the adults followed by the chloroform and hexane extracts.

BIOLOGICAL EVALUATION AND APPLICATION OF CORIANDER FRUITS AND ITS ESSENTIAL OIL

BIOLOGICAL EVALUATION AND APPLICATION OF CORIANDER FRUITS AND ITS ESSENTIAL OIL

Effect of the variation in vernalization temperature and gibberellic acid concentration on coriander productivity

Compared to the other plants of family Apiaceae, production of coriander fruits requires longer periods. Thus, controlling of flowering duration and shorten the period is considered a crucial act to reduce the production period with save irrigation water. Therefore, an experiment was conducted during the two successive seasons (2018/2019 and 2019/2020) to investigate the effect of vernalization by four different temperatures (control without cold, 0° C, 3° C and 6° C) and three concentrations of gibberellic acid, GA3, (0, 50 and 100 ppm) on vegetative growth, number of days to 50% flowering and maturity, fruits production and volatile oil percentage of coriander fruits. The experimental design was a Split-plot design with three replications. Results showed that the vernalized seeds at 3° C caused high significant effect on all studied characteristics where it gave the highest average of plant height, number of branches and umbls /, fruits yield, volatile oil percentages and oil yield (ml / plant), and reduction number of days to 50% flowering and maturity compared with other treatments. The application of GA3 at 100 ppm gave the highest average in above-stated parameters compared to other GA3 treatments. Concerning the effect of interaction treatments, the obtained results cleared that all studied characteristics showed the highest average as a result of the combination between vernalized seed at 3° C and 100 ppm of gibberellic acid (GA3). Treatments under study gave a pronounced effect on essential constituents where linalool is the main constituent. In conclusion, to decrease the number of days from planting to complete maturity and increased dry herb weight/plant vernalized seeds at 3° C treated with GA3 at 100 ppm should be exploited in coriander production systems.

Comparative characteristics of fruit tinctures of some representatives of the family Apiaceae

The family Apiaceae includes 474 genera and 3992–4050 species that are distributed around the globe. Of all the variety of species, our attention was drawn to the raw material of anise – Anisum vulgare Gaertrn.; fennel – Foeniculum vulgare Mill., which contains derivatives of phenylpropane; coriander – Coriandrum sativum L.; dill – Anethum graveolens L.; caraway – Carum carvi L., which is rich in monoterpenoid derivatives. These plants are widely used in medical practice and known to have antimicrobial, antispasmodic, expectorant, antihypertensive, diuretic, choleretic, carminative effects. This versatility is due to the presence of different groups of biologically active substances in the raw materials of plants. The aim of the research is to determine, by means of gas chromatography, a component composition of fruit tinctures of Anisum vulgare Gaertrn., Foeniculum vulgare Mill., Coriandrum sativum L. Anethum graveolens L. and Carum carvi L. Materials and methods. Tinctures were prepared in ratio 1:5 (extractant – 70 % ethyl alcohol) from anise, fennel, coriander, dill, and caraway fruits, which had been harvested in the experimental field of Zaporizhzhia State Medical University in August 2019. Qualitative and quantitative determination of the active compounds was performed using an Agilent 7890B gas chromatograph with a 5977B mass spectrometric detector. The NIST14 mass spectrum library was used to identify the components. Results. It has been revealed that the tinctures of Anisum vulgare Gaertrn., Foeniculum vulgare Mill., Coriandrum sativum L. Anethum graveolens L., and Carum carvi L. differ in qualitative and quantitative composition of components of chromato-mass spectrometry. Tinctures of Anethum fructus contain 28 components, among which 8.028 RT (-)-Carvone (52.63 %) and 4.861 RT D-Limonene (17.74 %) prevail. Tinctures of Coriandrum fructus contain 37 components with the highest content of 11,016 RT Benzene, 1-(1,5-dimethyl-4-hexenyl)-4-methyl (20.7 %) and 19.372 RT 1-(4-hydroxy-3-methoxyphenyl)dec-4-en-3-one (8.57 %). In the tincture of Carum carvi L., which contains 33 components, the following may be considered predominant: 7.988 RT Benzaldehyde, 4-(1-methylethyl) (47.37 %) and 19,311 RT undetermined compound (5.88 %). The tincture of Anisum fructus has 22 components, with the highest content of 8.531 RT Estragole (60.32 %) and 4.852 RT D-Limonene (5.15 %); Foeniculum fructus tincture contains 52 components, among which 5.745 RT Fenchone (15.39 %) and 8.5 RT Anethole (11.37 %) prevail. Conclusions. The results of gas chromatography of fruits of the Apiaceae family significantly expand the information about the chemical composition of raw materials and indicate the prospects for use in pharmaceutical and medical practice. Analyzing the results of gas chromatography, it has been found that tinctures of fruits of the Apiaceae family differ in qualitative and quantitative composition of components. Tinctures of Foeniculum fructus contain 52 components, Coriandrum fructus – 37 components, Carum carvi L. contain 33 components, Anethum fructus – 28 components, Anisum fructus – 22 components. The obtained experimental data can be used to create regulatory documentation for a particular type of medicinal plant raw materials.

Cultivation of Coriander in the Conditions of the Foothill Zone of the Republic of Ingushetia

This paper presents a comprehensive study of the features of growth and development of coriander. The study aims to assess the effect of fertilizers, sowing time and seeding rates on the passage of phenological phases, plant height, sowing quality of seeds, leaf area and essential oil content. The paper addresses the issue of using carbon derivatives (fullerenes) as growth stimulants. The effects of fertilizers and fullerenes on plant height and laboratory seed germination are compared. The effects of the pre-sowing application of nitrogen and phosphorus fertilizers and of foliar application of double superphosphate are highlighted and described. It is shown that the change in coriander leaves is dependent on the level of plant nutrient supply. The effects of sowing time and soil nutrient levels on the seed yield are considered. The study shows which factors had a greater impact on the content of essential oil in coriander fruits and, accordingly, on its harvest. The practical experience of coriander cultivation in the conditions of the foothill zone of the Republic of Ingushetia is summarized.
 Keywords: coriander, fertilizer, phenological phases, fullerenes, essential oil

STUDY THE RESPONSE OF GROWING SOME CULTIVARS OF CORIANDER (Coriandrum sativum L.) SOWING AT DIFFERENT DATES

The present investigation on coriander (Coriandrum sativum L.) included three sowing dates viz. 15th October (D1), 30th October (D2) and 15thNovember (D3) and four selected cultivars; Baladi (C1), Syrian (C2), Indian (C3) and Sudan cultivars (C4). The experiment was conducted during two successive cultivation seasons of 2018/2019 and 2019/2020 in the experimental farm of Assuit. This experiment carried out to assess yield, quality and economics of coriander cultivars under agro-ecological conditions of this region. Phenological traits (time to flowering initiation, maturation and harvest), along with morphological characters, yield and two chemical traits related to seed composition were evaluated. As a result of this study, all investigated characters of coriander were varied significantly, as well as the maximum number of branches, number of umbels / plants, seed yield/ plot and seed yield/ fed. were recorded in the plants sown on 15th October followed by 30th October. The essential oil percentage from coriander fruits was ranged between 0.26% and 0.63%. Linalool was found to be the principal constituent. The other major compounds were Alpha pinene, Limonene, Citronellal and geranyl acetate. The maximum oil percentage was recorded in Syrian cultivar at all dates. Results revealed that parameters like minimum days to flowering initiation, minimum days to 50% fruit maturation and minimum days to harvest were recorded with Indian followed by Syrian cultivars at different dates. The result of experiment revealed that the D1 significantly improved growth parameters among all the dates of sowing. The best results were obtained from Baladi, Syrian cultivars, with respect to fruits yield and essential oil respectively.

Optimization of agricultural practices in winter crops Coriandrum sativum L.

The total volume of world production of essential oil products reaches 250 thousand tons per year, which use up to 300 species of cultivated plants and wild-growing volatile-oil-bearing plants. The soil and climatic conditions in the south of Russia are favorable for the successful development of the essential oil industry, which is important for our country. Sowing coriander (Coriandrum sativum L.) is the most common essential oil culture of the Russian Federation and countries of the Union of Independent States. Its crops occupy about 82.4% of all areas of volatile-oil-bearing plants. Coriander fruits contain from 1.5 to 1.8% essential oil. The main component of the essential oil, linalool, and serves as the initial product for the production of a number of fragrant substances with the smells of lemon, orange, rose, violet, etc., which are successfully used in the perfumery, food, and distillery industries. Coriander is also a honey plant. Due to the growth in demand and gross purchases of coriander seeds associated with its high purchase price, problems arose with increasing its productivity and improving the technology of cultivation. Due to the large volumes of sales of both coriander raw materials and finished products, the levels of profitability and net income of farms both in the Republic of Crimea and in the Russian Federation as a whole, as well as the development of the agro-industrial complex will significantly increase. The above analysis of domestic and foreign literature in this review article shows that winter coriander crops are most productive compared to spring crops. Introduction to the production of winter crops of coriander, with the implementation of all elements of the cultivation technology, is a promising direction of its cultivation in the Crimea, as it allows more efficient use of soil moisture, which accumulates during the autumn-winter period.

Production of value added Oyster mushrooms

Mushrooms are ironic in nutrimental resources and have converted into one of the common foods in the previous twenty years globally. The types of edible mushrooms are button, milky and oyster mushrooms. The research aimed at value addition of Oyster mushrooms by rising on paddy substrate complemented with two concentrations of four different medicinal plants. The plant parts selected were flowers of Butea monosperma, leaves of Moringa olifera, bark of Cinnamonom zeylianicum, fruits of Corindraum sativum at 5% and 10% concentration. Different species of oyster mushrooms are available. In the present study Pleurotus florida was selected for value addition. Maximum mycelium running rate was detected in Cinnamon bark (5%) and paddy straw (95%) accompanied group and lowermost running rate of mycelium was observed in Moringa leaf (5%) and paddy straw (95%). The primordial arrival was fast with Cinnamon bark (5%) supplemented group and slowest in Moringa leaf (5%) supplemented group. The mushrooms grownup on Coriander fruit (5%) produced more but the growth was slow. Mushrooms supplemented with Butea flower (5%) exhibited slow growth and yield was next to coriander fruit supplemented mushrooms. The produced mushrooms were subjected to physical evaluation, preliminary phytochemical testing and also tested for estimation of total flavonoids, total phenols, total tannins and total cinnamaldehyde contents. Value addition of Oyster mushrooms was successful with cinnamon bark as cinnamaldehyde was noticed in the Cinnamon bark supplemented group, and also with Moringa leaves as flavonoids was observed in more concentration in Moringa leaf supplemented mushroom group.

SPECTROPHOTOMETRIC AND HPTLC STUDIES ON SELECTED INDIAN SPICE EXTRACTS

The present work was carried out with a view to analyze the major phytochemical compounds of Indian spices, dalchini (Cinnamon zeylanicum) bark and coriander (Coriander sativum) fruit. Hydro-alcoholic extracts were prepared from selected spices and analyzed for extract yield, loss on drying (LOD) and pH. phytochemical compounds such as total alkaloids, phenols, flavonoids and tannins were quantified by spectrometric methods. Hydro-alcoholic extracts from selected spices revealed the pH to be between 5.36-5.62, loss on drying 12.54–15.41% and extract yield 8.62–29.19%w/w. Among the investigated samples, higher levels of alkaloids (2.63%) and flavanoids (3.42%) were found in C. sativum while C. zeylanicum exhibited high content of total phenolics (3.35%) and tannins (0.82%). The hydro-alcoholic extracts were subjected to HPTLC analysis and the results suggested the presence of two different major phytochemical compounds in C. zeylanicum, whereas Coriander sativum extract displayed three major peak. C. sativum extracts showed relatively similar spots with Rf values, which indicates the presence of four similar types of flavonoids in each extract. Due to the presence of various phytochemical constituents and favorable extract yield, LOD and pH, the presently investigated spice extracts can be used in drug formulations.

UJI AKTIVITAS SITOTOKSIK EKSTRAK METANOL BUAH KETUMBAR (Coriandrum sativum Linn) TERHADAP ARTEMIA SALINA LEACH DENGAN UJI BSLT (Brine Shrimp Lethality Test)

Coriander is a common herb can be used as traditional medicine. One of the expected benefits of Coriander fruits is an anti-cancer. This study aims to determine the cytotoxic activity of Coriander extract (Coriandrum sativum Linn) on shrimp larvae (Artemia salina Leach) with the BSLT (Brine Shrimp Lethality Test) method. Coriander fruits was extracted using methanol solvent and maceration method, then concentrated it with a rotary evaporator until a thick extract. Cytotoxic activity test used methanol extract with several concentration : 1,000 ppm, 100 ppm, 10 ppm, and 1 ppm. The result of this research reveal that methanol extract of Coriander fruits has cytotoxic activity with LC50 value is 32.35 ppm.

Potassium sources and doses in coriander fruit production and essential oil content

ABSTRACT Potassium (K) is one of the most required agricultural crop macronutrients, with potassium chloride being the most applied source. However, this fertilizer is not recommended for several crops due to its high chlorine content, promoting final product quality losses, thus being replaced by potassium sulphate. The aim of the present study was to evaluate the production and macronutrient, essential oil and linalool contents of coriander fruits submitted to different potassium sources and doses. The research was performed in a greenhouse, in plastic 46 kg boxes applying a mixture of soil and sand as substrate. The experimental design was of randomized blocks, applying a 2x4 factorial arrangement, with two potassium sources (potassium chloride and sulphate) at four doses (50, 100, 150 and 200 mg of K/kg substrate), performing four replicates. The highest fruit yields, and phosphorus and sulfur fruit contents were verified in plants fertilized with K2SO4. The application of increasing potassium doses, regardless of the source, resulted in increased K and decreased Ca contents and did not affect N and Mg fruit levels in the fruits. The highest essential oil concentration in fruits (0.15 g) and linalool in essential oils (0.42 mg) were verified when 153.8 and 131.3 mg of K/kg substrate using K2SO4 were applied, respectively.

Novel compounds in fruits of coriander (Coşkuner & Karababa) with anti-inflammatory activity

Abstract Coriander, Coriandrum Sativum L., is one of the commonest food and medicinal plants in many countries, but its chemical ingredients and pivotal role in anti-inflammatory activity have not been fully explored. The present study aimed to identify new compounds in the fruits of coriander and explore their anti-inflammatory activity. The compounds were isolated by chromatographic seperations and identified using spectroscopic and spectrometric methods. RAW264.7 macrophage cells were used to detect the anti-inflammatory activity of the compounds via Griess assay, western blotting, ELISA, and flow cytometry methods. The study resulted in the discovery of four new compounds, which were identified as: 4α-(furo[2,3-d]pyrimidin-6′-ylmethyl)-9α-propylnonolactone (1), 4-(formyloxy)-4-(6′-methylcyclohex-1-en-1-yl)butanoate(2), (7α,8α)-3α-hydroxyl-12,13α-dimethyl-5(6)-en-bicyclo[5,3,0]caprolactone (3), 7-methoxy-4-methyl-5,6-dihydro-7H-(2-hydroxypropan-2-yl)furo[2,3-f] coumarin (4). Compound 3 showed the highest anti-inflammatory activity with IC50 of 6.25 μM for an inhibitory effect on nitrite oxide (NO) level. In addition, compound 3 decreased the lipopolysaccharides-stimulated generations of ROS and the inflammatory cytokines (IL-6 and TNF-α). Mechanism exploration indicated that compound 3 suppressed inflammatory mediators’ expression, like iNOS and COX-2. Furthermore, the NF-κB and MAPK pathways were involved in the anti-inflammatory process of compound 3.

Fatty acid composition and oil content during coriander fruit development

Coriander contains petroselinic acid, an isomer fatty acid of oleic acid. Coriander seed oil has been proposed as novel food ingredient in the European Union. Field experiments were performed at Auch (France) during two seasons (2010 and 2011). From flowering to maturity, fruits were harvested weekly and oil content and fatty acid (FA) compositions were determined. Fruits presented 2% more oil in 2010 than in 2011. Petroselinic acid (PA) contents was higher in 2011 than in 2010. Oil accumulation began earlier after flowering (2 DAF) in 2011. A first step in accumulation was identified between two and 21 DAF characterized by high SFA and PUFA, which decreased 21 DAF. Subsequently, PA increased to its highest concentration (30–55 DAF) and SFA and PUFA reached their lowest. These results suggest that higher concentrations of PA can be achieved by collecting fruits before full maturity.

Transcriptome profiling of coriander: a dual purpose crop unravels stem gall resistance genes

Stem gall (Protomyces macrosporus Unger), a serious disease that affects leaves, petioles, stems and fruits of coriander (Coriandrum sativum L.) causing heavy loss in yield. Genetic improvement of coriander for stem gall disease is indispensable. Coriander cultivars of stem gall resistance (ACr-1) and susceptible (CS-6) leaf samples were utilized and transcriptome sequenced using Illumina NextSeq500 platform. After trimming low-quality reads and adapter sequences, a total of 49,163,108 and 43,746,120 high-quality reads were retained and further assembly resulted validated transcripts of 59,933 and 56,861. We have predicted 52,506 and 48,858 coding sequences (CDS) ofwhich 50,506 and 46,945 were annotated using NCBInr database. Gene ontology analysis annotated 19,099 and 17,625 terms; pathway analysis obtained 24 different functional pathway categories; signal transduction, transport, catabolism, translation and carbohydrate metabolism pathways etc. were dominated. Differentially expressed genes analysis predicted 13,123 CDS commonly expressed of which 431 and 400 genes were significantly upregulated and downregulated, respectively, in which Rgenes, stress inducible transcription factors such as ERF, NAC, bZIP, MYB, DREB and WRKY and antifungal related genes were predicted. The real-time PCR analysis of HSP20 gene expression in resistance showed upregulation by 10-fold over susceptible sample and 18s used as a housekeeping gene for normalization. The present results provide an insights into various aspects underlying the development of resistance to stem gall in coriander.

The Effect of Trichoderma spp. on the Composition of Volatile Secondary Metabolites and Biometric Parameters of Coriander (Coriandrum sativum L.)

The aim of this work was to investigate the influence of Trichoderma spp. on volatile secondary metabolites and biometric parameters obtained from coriander (Coriandrum sativum L.). The fruits of coriander treated with liquid suspension spores of T. harzianum strain T22 and of T. asperellum strain B35 increased the yield of essential oil (by ∼36%); however, it was unaffected in its composition. Moreover, Trichoderma spp. influenced the yield and increased the number of seeds of coriander by ∼60%. Inoculation seeds with T. asperelleum strain B35 caused about 2-fold increase in the biomass of the aerial parts of coriander. There was also an increased root colonization by the fungus Trichoderma spp., limiting the number of phytopathogenic fungi from genus Fusarium observed.

The Safety of Mother's Milk® Tea: Results of a Randomized Double-Blind, Controlled Study in Fully Breastfeeding Mothers and Their Infants.

Various natural products are reported to improve maternal milk supply yet are not necessarily safe for infants. Researchers have not systematically studied galactagogue teas for safety. This study evaluates the safety of a galactagogue tea in breastfeeding women and their infants, assessing short- and long-term adverse effects. Healthy, exclusively/fully breastfeeding women ( N = 60) with no milk insufficiency were randomized into (1) an all-natural tea containing fruits of bitter fennel, anise, and coriander; fenugreek seed; and other herbs (Mother's Milk® herbal tea; test) group or (2) a lemon verbena leaf (placebo) group. Maternal diaries captured self-reported maternal and infant adverse effects, tea consumed, and perceived infant satisfaction. Maternal quality of life and psychological state were assessed at baseline and 2 and 4 weeks. Poststudy calls assessed adverse effects through the infants' age of 12 months. No adverse effects attributable to the interventions were reported at any time point. No differences were found between test and placebo groups in sociodemographic characteristics, maternal or infant adverse symptoms, quality of life, breastfeeding self-efficacy, maternal psychological measures, infant growth, and infant satisfaction (all p >.05). This double-blind, randomized controlled trial (RCT) of an herbal galactagogue versus placebo among healthy, exclusively/fully breastfeeding mothers and infants found no adverse events associated with the test tea across the 30-day study or the first year of their infant's life. This composite tea appears to present no safety risk for mothers or their young babies.

Coriander (Coriandrum sativum L.) response to different levels of agronomic factors in Poland

Crop yields are determined by complex interactions between various agronomic factors. Knowledge of crop responses to various levels of agronomic inputs and their interactions is essential for developing high-yielding production technologies. Field experiments with the sk−p fractional factorial design are highly useful for selecting the optimal production technology for crops whose agronomic requirements have been insufficiently researched under specific agroecological conditions.A field experiment with the sk−2 fractional factorial design and resolution IV, with five factors (k = 5) at three levels (s = 3), was performed at the Agricultural Experiment Station in Bałcyny (north-eastern Poland) in 2006–2008. Experiments with the 35−2 fractional factorial design offer a rapid and relatively cheap method for determining the influence of various agronomic factors and their interactions on crop yields. The results of multifactorial experiments conducted under the same weather and soil conditions facilitate the choice of the optimal production technology and the determination of the optimal intensity of the main agronomic treatments.This study analyzed the responses of coriander to the key yield-forming factors (seeding date, rates of phosphorus, potassium, magnesium, sulfur, and micronutrient fertilization) and yield-protection factors (weed control and fungal disease management). In the agroecological conditions of north-eastern Poland, weed control had a significant influence on the yield of coriander fruits. The highest fruit yield was obtained in the treatment where herbicide (1500 g ha−1 metobromuron) was applied to the soil after sowing. Mechanical weed control (single inter-row treatment in the two leaves unfolded stage) reduced fruit yields by nearly 20%, whereas the absence of weed control decreased fruit yields by 62%. The treatments where various weed control methods were applied differed in the number of coriander plants m−2. Chemical weed control increased stem length, the number of primary branches, the number of inflorescences (umbels), and fruit mass. The responses of coriander plants to delayed sowing were determined by precipitation levels during the growing season. In seasons with abundant precipitation (398–425 mm), delayed sowing decreased fruit yield by around 15–19%. In years with low precipitation (193–319 mm), a 14-day delay in sowing was well tolerated by coriander plants. Mineral fertilization (P, K, S, Mg, and micronutrients) had no significant effect on the growth, development or yield of coriander. Coriander plants also demonstrated a weak (non-significant) response to chemical disease control.