Core-sheath Fibers Research Articles

Efficient and Secure Encapsulation of a Natural Phase Change Material in Nanofibers Using Coaxial Electrospinning for Sustainable Thermal Energy Storage.

In this study, we present an ecofriendly technique for encapsulating lauric acid (LA), a natural phase change material, within polystyrene (PS) nanofibers through coaxial electrospinning. The resulting LAPS core-sheath nanofibers exhibited a melting enthalpy of up to 136.6 J/g, representing 75.8% of the heat storage capacity of pristine LA (180.2 J/g), a value surpassing all previously reported core-sheath fibers. Scanning electron microscopy revealed uniform LAPS nanofibers free of surface LA until the core LA feed rate reached 1.3 mL/h. As the core LA feed rate increased, the fiber diameter shrank from 2.24 ± 0.31 to 0.58 ± 0.45 μm. Infrared spectra demonstrated a proportional increase in the LA content with rising core LA injection rates. Thermogravimetric analysis found the maximum core LA content in core-sheath nanofibers to be 75.0%. Differential scanning calorimetry thermograms displayed a trend line shift upon LA leakage for LA1.3PS nanofibers. LAPS fibers containing 75.0% LA effectively maintained consistent cycling stability and reusability across 100 heating-cooling cycles (20-60 °C) without heat storage deterioration. The core LA remained securely within the PS sheath after 100 cycles, and the LAPS nanofibers retained an excellent structural integrity without rupture. The energy-dense and form-stable LAPS core-sheath nanofibers have great potential for various thermal energy storage applications, such as building insulation, smart textiles, and electronic cooling systems, providing efficient temperature regulation and energy conservation.

Coaxially printed magnetic mechanical electrical hybrid structures with actuation and sensing functionalities

Soft electromagnetic devices have great potential in soft robotics and biomedical applications. However, existing soft-magneto-electrical devices would have limited hybrid functions and suffer from damaging stress concentrations, delamination or material leakage. Here, we report a hybrid magnetic-mechanical-electrical (MME) core-sheath fiber to overcome these challenges. Assisted by the coaxial printing method, the MME fiber can be printed into complex 2D/3D MME structures with integrated magnetoactive and conductive properties, further enabling hybrid functions including programmable magnetization, somatosensory, and magnetic actuation along with simultaneous wireless energy transfer. To demonstrate the great potential of MME devices, precise and minimally invasive electro-ablation was performed with a flexible MME catheter with magnetic control, hybrid actuation-sensing was performed by a durable somatosensory MME gripper, and hybrid wireless energy transmission and magnetic actuation were demonstrated by an untethered soft MME robot. Our work thus provides a material design strategy for soft electromagnetic devices with unexplored hybrid functions.

Influence of interfacial compatibility on the crystallization behavior of electrospun core–sheath fibers

Core–sheath fibers composed of a crystalline polymer [poly(ethylene oxide) (PEO)] in the core and amorphous polymers [polystyrene (PS) and poly(methyl methacrylate) (PMMA)] in the sheath were fabricated through coaxial electrospinning. Because the melting temperature of PEO is lower than the glass transition temperatures of PS and PMMA, PEO crystallization was hard-confined within the immobile sheath. In immiscible PEO/PS fibers and miscible PEO/PMMA fibers, hard confinement reduced the crystallizability of PEO; therefore, its crystallite size, degree of crystallinity, and crystallization kinetics decreased with decreases in the degree of confinement. Confinement hindered PEO crystallization to a greater extent when the core and sheath polymers were miscible than when they were not. The favorable interaction between PEO and PMMA facilitated their interdiffusion during electrospinning, which caused the increased confinement of PEO in the core. Furthermore, when the compatibility between the solvents used for coaxial electrospinning increased, they enhanced the interdiffusion of the core and sheath polymers, which hindered PEO crystallization. However, the compatibility between polymers influenced the crystallization behavior of PEO to a considerably greater extent than did the compatibility between solvents.

Electrospun Fibers of Biocompatible and Biodegradable Polyesters, Poly(Ethylene Oxide) and Beeswax with Anti-Bacterial and Anti-Fungal Activities

Fibrous materials composed of core–sheath fibers from poly(ethylene oxide) (PEO), beeswax (BW) and 5-nitro-8-hydroxyquinoline (NQ) were prepared via the self-organization of PEO and BW during the single-spinneret electrospinning of a homogeneous blend solution of the partners. Additionally, the application of the same approach enabled the preparation of fibrous materials composed of core–double sheath fibers from PEO, poly(L-lactide) (PLA) and NQ or 5-chloro-7-iodo-8-hydroxyquinoline (CQ), as well as from PEO, poly(ε-caprolactone) (PCL) and NQ. The consecutive selective extraction of BW and of the polyester with hexane and tetrahydrofuran, respectively, evidenced that core–double sheath fibers from PEO/polyester/BW/drug consisted of a PEO core, a polyester inner sheath and a BW outer sheath. In order to evaluate the possibility of the application of fibrous materials from PEO/BW/NQ, PEO/PLA/BW/NQ, PEO/PCL/BW/NQ and PEO/PLA/BW/CQ for plant protection, microbiological studies were performed using both phytopathogenic microorganisms (Pseudomonas corrugata, Fusarium graminearum and Fusarium avenaceum) and beneficial microorganisms (Pseudomonas chlororaphis, Bacillus amyloliquefaciens and Trichoderma asperellum). It was found that the fibrous materials had anti-bacterial and anti-fungal activity against both phytopathogenic and beneficial microorganisms. This is the first report on the activity of fibrous materials loaded with 8-hydroxyquinoline derivatives not only against phytopathogenic but also against beneficial microorganisms that are of importance in agriculture.

Flexible and conductive core-sheath fiber using multifunctional merocyanine as a smart electrolyte for a high-performance fibrous visible light sensor

Flexible conductive fibers have attracted significant attention in the wearable electronics field because of light weight, small size, and easy shape morphing. To date, there are few reports on multifunctional flexible conductive fibers. Finding a facile and effective solution for large-scale production of flexible conductive fibers is still a challenge. In this work, a flexible core-sheath fiber with excellent electrical conductivity (24.71 Ω·m) and visible light sensing is fabricated, which contains a merocyanine diol (MC(OH)2)/CrCl3·6H2O/ethanol aqueous solution core layer and a silicon rubber outer layer. The synthesized MC(OH)2 is an intelligent molecular switch with a visible light response that can reversibly convert from open-form MC(OH)2 to closed-form spiropyran diol (SP(OH)2) after short visible light irradiation. In the reverse process, the transition from SP(OH)2 to MC(OH)2 can occur gradually in the dark. This can be used to sense visible light in addition to electrical conductivity. The reversible change in the electrical resistance of the MC(OH)2/CrCl3·6H2O/ethanol aqueous solution reaches 15.59%. This fiber shows excellent electrical conductivity, good flexibility, a sensitive visible light response, good photochromism, a simple structure, low cost, easy preparation, and suitability for industrial large-scale production, offering promise for applications in the fields of flexible and wearable electronics.

Interfacial Capillary Spooling of Conductive Polyurethane-Silver Core-Sheath (PU@Ag) Microfibers for Highly Stretchable Interconnects.

Conductive fibers are core materials in textile electronics for the sustainable operation of devices under mechanical stimuli. Conventional polymer-metal core-sheath fibers were employed as stretchable electrical interconnects. However, their electrical conductivity is severely degraded by the rupture of metal sheaths at low strains. Because the core-sheath fibers are not intrinsically stretchable, designing a stretchable architecture of interconnects based on the fibers is essential. Herein, we introduce nonvolatile droplet-conductive microfiber arrays as stretchable interconnects by employing interfacial capillary spooling, motivated by the reversible spooling of capture threads in a spider web. Polyurethane (PU)-Ag core-sheath (PU@Ag) fibers were prepared by wet-spinning and thermal evaporation. When the fiber was placed on a silicone droplet, a capillary force was generated at their interface. The highly soft PU@Ag fibers were fully spooled within the droplet and reversibly uncoiled when a tensile force was applied. Without mechanical failures of the Ag sheaths, an excellent conductivity of 3.9 × 104 S cm-1 was retained at a strain of 1200% for 1000 spooling-uncoiling cycles. A light-emitting diode connected to a multiarray of droplet-PU@Ag fibers exhibited stable operation during spooling-uncoiling cycles.

Piezoelectric Enhancement of Piezoceramic Nanoparticle-Doped PVDF/PCL Core-Sheath Fibers

Electrospinning is considered to be an efficient method to prepare piezoelectric thin films because of its ability to transform the phase of the polymers. A core-sheath structure can endow fibers with more functions and properties. In this study, fibers with a core-sheath structure were prepared using polyvinylidene fluoride (PVDF) included with nanoparticles (NPs) as the shell layer and polycaprolactone (PCL) as the core layer. Their mechanical and piezoelectric properties were studied in detail. During the course of the electrospinning process, PVDF was demonstrated to increase the amount of its polar phase, with the help of nanoparticles acting as a nucleating agent to facilitate the change. PCL was chosen as a core material because of its good mechanical properties and its compatibility with PVDF. Transmission electron microscope (TEM) assessments revealed that the fibers have a core-sheath structure, and shell layers were loaded with nanoparticles. Mechanical testing showed that the core layer can significantly improve mechanical properties. The XRD patterns of the core-sheath structure fibers indicated the β phase domain the main component. Piezoelectric testing showed that the doped nanoparticles were able to enhance piezoelectric performances. The increases of mechanical and piezoelectric properties of core-sheath structure fibers provide a feasible application for wearable electronics, which require flexibility and good mechanical properties.

Electrospun Core-Sheath Fibers with a Uniformly Aligned Polymer Network Liquid Crystal (PNLC).

Electrospun polymer-liquid crystal (PLC) fibers have potential applications such as wearable sensors and adaptive textiles because of their rapid response and high flexibility. However, existing PLC fibers only have a narrow responsive range and poor resistance to heat and chemicals. Herein, a new type of PLC fiber is prepared by using a coaxial electrospinning process. The core solution is 4'-pentyl-4-biphenylcarbonitrile (5CB), and the sheath solution is a mixture containing 13 wt % PVP and 10 wt % reactive mesogen (RM). After UV exposure of the fibers, 5CB in the core and RM diffusing from the core are cross-linked into an LC polymer. The fibers have a highly uniform morphology with an average diameter of 3.2 ± 0.5 μm, and mesogens inside the fibers align unidirectionally with the long axis of the fibers. The fibers show a broad phase-transition temperature range between 13.5 and 155.5 °C and have a response time of less than 10 s. The temperature range can also be controlled by adjusting components in the electrospun fibers and UV exposure time. The core-sheath fibers prepared in such a manner exhibit excellent heat and chemical resistance with reversible optical responses. Moreover, when the fibers are exposed to volatile organic compounds (VOCs) such as toluene, the fibers show a rapid optical response to toluene vapor within 25 s. This study demonstrates that the fibers are potentially useful for preparing flexible temperature and chemical sensors.

Electrospun Core–Sheath PVDF Piezoelectric Fiber for Sensing Application

In recent years, piezoelectric polymer sensors are used in energy harvesting and self-powered sensing due to their flexibility, low density, and high piezoelectric constant, and their performances may be improved through a careful architectural design. Herein, we reported a facile strategy for fabricating core-sheath piezoelectric fiber (C-PEF) by directly electrospinning poly(vinylidene fluoride) (PVDF) onto the stainless steel wires. Such C-PEF can well respond to bending deformation with different degrees, and therefore it can be assembled into a piezoelectric bending sensor for airflow speed sensing. Furthermore, spring-like structured C-PEF (S-C-PEF) can serve as a piezoelectric spring sensor and in a sophisticated manner monitor human sleep behavior. This work paves a way for developing multigeometric piezoelectric sensors though a low-cost, facile, and reliable method, showing potential applications including bending sensing and health monitoring.

Unique Fiber Morphologies from Emulsion Electrospinning—A Case Study of Poly(ε-caprolactone) and Its Applications

The importance of electrospinning to produce biomimicking micro- and nano-fibrous matrices is realized by many who work in the area of fibers. Based on the solubility of the materials to be spun, organic solvents are typically utilized. The toxicity of the utilized organic solvent could be extremely important for various applications, including tissue engineering, biomedical, agricultural, etc. In addition, the high viscosities of such polymer solutions limit the use of high polymer concentrations and lower down productivity along with the limitations of obtaining desired fiber morphology. This emphasizes the need for a method that would allay worries about safety, toxicity, and environmental issues along with the limitations of using concentrated polymer solutions. To mitigate these issues, the use of emulsions as precursors for electrospinning has recently gained significant attention. Presence of dispersed and continuous phase in emulsion provides an easy route to incorporate sensitive bioactive functional moieties within the core-sheath fibers which otherwise could only be hardly achieved using cumbersome coaxial electrospinning process in solution or melt based approaches. This review presents a detailed understanding of emulsion behavior during electrospinning along with the role of various constituents and process parameters during fiber formation. Though many polymers have been studied for emulsion electrospinning, poly(ε-caprolactone) (PCL) is one of the most studied polymers for this technique. Therefore, electrospinning of PCL based emulsions is highlighted as unique case-study, to provide a detailed theoretical understanding, discussion of experimental results along with their suitable biomedical applications.

Oral empagliflozin-loaded tri-layer core-sheath fibers fabricated using tri-axial electrospinning: Enhanced in vitro and in vivo antidiabetic performance

Empagliflozin (EM) was successfully loaded in polycaprolactone/poly (L-lactic acid)/polymethyl methacrylate (PCL/PLA/PMMA) fibers. In the rat β-cell line (BRIN-BD11), the insulin expression ratio of pancreatic β-cells was stimulated at high and low glucose by culturing with tri-layer EM-loaded fiber (EMF) for 48 h. The expression ratios of glucokinase and GLUT-2 proteins increased after EMF treatment. According to the in vitro drug release test, 97% of all drug contained in fibers was released in a controlled manner for 24 h. The pharmacokinetic test revealed that the bioavailability was improved ∼4.8-fold with EMF treatment compared to EM-powder and blood glucose level was effectively controlled for 24 h with EMF. Oral administration of EMF exhibited a better sustainable anti-diabetic activity even in the half-dosage than EM-powder in streptozotocin/nicotinamide-induced T2DM rats. The levels of GLP-1, PPAR-γ, and insulin were increased while the levels of SGLT-2 and TNF-α were decreased with EMF treatment. Also, EMF recovered the histopathological changes in the liver, pancreas, and kidney in T2DM rats and protected pancreatic β-cells. Consequently, EMF is suggested as an unprecedented and promotive treatment approach for T2DM with a higher bioavailability and better antidiabetic effect compared to conventional dosage forms.

Hybrid Fiber Materials according to the Manufacturing Technology Methods and IOT Materials: A Systematic Review

With the development of convergence technology, the Internet of Things (IoT), and artificial intelligence (AI), there has been increasing interest in the materials industry. In recent years, numerous studies have attempted to identify and explore multi-functional cutting-edge hybrid materials. In this paper, the international literature on the materials used in hybrid fibers and manufacturing technologies were investigated and their future utilization in the industry is predicted. Furthermore, a systematic review is also conducted. This includes sputtering, electrospun nanofibers, 3D (three-dimensional) printing, shape memory, and conductive materials. Sputtering technology is an eco-friendly, intelligent material that does not use water and can be applied as an advantageous military stealth material and electromagnetic blocking material, etc. Electrospinning can be applied to breathable fabrics, toxic chemical resistance, fibrous drug delivery systems, and nanoliposomes, etc. 3D printing can be used in various fields, such as core-sheath fibers and artificial organs, etc. Conductive materials include metal nanowires, polypyrrole, polyaniline, and CNT (Carbon Nano Tube), and can be used in actuators and light-emitting devices. When shape-memory materials deform into a temporary shape, they can return to their original shape in response to external stimuli. This study attempted to examine in-depth hybrid fiber materials and manufacturing technologies.

One-step coaxial spinning of core-sheath hydrogel fibers for stretchable ionic strain sensors

High-strength, highly conductive, and stretchable conductive fibers are essential for the development of flexible electronic devices. Here, we develop a continuous coaxial wet-spinning method to fabricate stretchable, conductive, and freeze-resistant hydrogel fibers with a core-sheath structure. The core is a supramolecular hydrogel, poly (APhe-co-AAm) (PAPAM), obtained by radical polymerization of acrylamide (AAm) and acryloyl-l-phenylalanine (APhe), and the sheath consists of PVDF-HFP and PU with hydrochloric acid as the coagulation bath. The hydrogel fibers exhibit excellent mechanical properties with a tensile strength of 3.1 MPa and elongation at a break of 750 %. Hydrochloric acid plays two roles in this system: one is to promote hydrophobic association and hydrogen bond formation and improves mechanical properties, and the other is to provide plentiful ions to confer excellent electrical conductivity (10.59 S m−1) and freezing resistance (-20 °C). The application of fiber strain sensors for detecting human motion and pressure sensing demonstrates great potential as wearable electronic devices.

Core/Double-Sheath Composite Fibers from Poly(ethylene oxide), Poly(L-lactide) and Beeswax by Single-Spinneret Electrospinning.

The conventional approach for preparation of core-sheath fibers is coaxial electrospinning. Single-spinneret electrospinning of emulsions is a much less common method to obtain core-sheath fibers. Core-sheath structure may be generated by electrospinning of homogeneous blend solutions; however, reports on such cases are still scarce. Herein, the preparation of nanofibrous composites from poly(ethylene oxide) (PEO), poly(L-lactide) (PLA) and beeswax (BW) by single-spinneret electrospinning of their homogeneous blend solutions in chloroform is reported. The produced fibers had core/double-sheath structure with a PEO core, PLA inner sheath and BW outer sheath. This original fiber structure was evidenced by transmission electron microscopy, selective extraction of BW or PEO, and X-ray photoelectron spectroscopy. The PLA/BW double sheath led to hydrophobicity of the PEO/PLA/BW mats. The tensile tests revealed that PEO/PLA/BW mats had substantially improved mechanical behavior as compared to PEO, PLA and PEO/BW mats. PEO/PLA/BW mats can be used as drug carriers as evidenced by the one-pot incorporation of the model drug 5-nitro-8-hydroxyquinoline (NQ) into the fibrous materials. Microbiological tests showed that PEO/PLA/BW/NQ had antimicrobial activity. Therefore, the new materials are promising for wound healing applications.

An ultra-sensitive core-sheath fiber strain sensor based on double strain layered structure with cracks and modified MWCNTs/silicone rubber for wearable medical electronics

Flexible resistive sensors have attracted widespread attention in the field of wearable electronics. Inspired by the single-layer crack structure which has ultra-high sensitivity, a double strain layered crack structure is proposed to expand the maximum working strain (30%) of flexible sensor while maintaining the ultra-high sensitivity (GF = 2165 at 0–30% and 7381 at 25–30%). MWCNTs modified by 3-Aminopropyltriethoxysilane were filled into silicon rubber to form nanocomposites with fast response times (42 ms), high repeatability (>1000) and low hysteresis (7.08%). Furthermore, the respiratory rate, heart rate and blood pressure can be measured by the proposed sensor. The average errors of the respiratory rate and heart rate are less than 2% and 3% respectively. The mean error of systolic blood pressure, diastolic blood pressure and mean blood pressure is −0.0042 mmHg, 0.3730 mmHg, and 0.2472 mmHg respectively, meeting the standards of Association for the Advancement of Medical Instrumentation and A-level British Hypertension Society. This study shows that the proposed sensor has broad application prospects in high-precision wearable medical electronics.

Hydrophilic Core-Sheath fibers of polyvinyl alcohol / polyethylene composites through in situ ethylene polymerization

Core - sheath fibers of polyvinyl alcohol/polyethylene composites are synthesized by ethylene polymerization with titanium tetrachloride incorporated PVA nanofiber (NF) as catalyst precursor in presence of methyl aluminoxane (MAO) as a cocatalyst. The process also involves the initial preparation of PVA nanofiber by electrospinning followed by its reaction with titanium tetrachloride. The obtained titanium incorporated PVA was found to be insoluble in protonic solvent due to the reaction of OH group in PVA with titanium tetrachloride leading to the formation of a cross-linked mat. Thermal analysis of core-sheath fiber composite indicated the presence of polyethylene due to observation of melting peak at 134 °C. PVA-PE fiber composite is characterized by FTIR, SEM, and contact angle data. The results demonstrate that the presented approach is useful for synthesizing incompatible classes of polymer composite fibers such as polyvinyl alcohol/polyethylene with core-sheath morphology.

Nitrogen-Doped Porous Core-Sheath Graphene Fiber-Shaped Supercapacitors.

In this study, a strategy to fabricate nitrogen-doped porous core-sheath graphene fibers with the incorporation of polypyrrole-induced nitrogen doping and graphene oxide for porous architecture in sheath is reported. Polypyrrole/graphene oxide were introduced onto wet-spun graphene oxide fibers by dip-coating. Nitrogen-doped core-sheath graphene-based fibers (NSG@GFs) were obtained with subsequently thermally carbonized polypyrrole/small-sized graphene oxide and graphene oxide fiber slurry (PPY/SGO@GOF). Both nitrogen doping and small-sized graphene sheets can improve the utilization of graphene layers in graphene-based fiber electrode by preventing stacking of the graphene sheets. Enhanced electrochemical performance is achieved due to the introduced pseudo-capacitance and enhanced electrical double-layered capacitance. The specific capacitance (38.3 mF cm−2) of NSG@GF is 2.6 times of that of pure graphene fiber. The energy density of NSG@GF reaches 3.40 μWh cm−2 after nitrogen doping, which is 2.59 times of that of as-prepared one. Moreover, Nitrogen-doped graphene fiber-based supercapacitor (NSG@GF FSSC) exhibits good conductivity (155 S cm−1) and cycle stability (98.2% capacitance retention after 5000 cycles at 0.1 mA cm−2).

Core-sheath phase change fibers via coaxial wet spinning for solar energy active storage

Using phase change fibers (PCFs) will help buffer the changes in ambient temperature, improve the utilization of natural energy, and ease the energy crisis. However, the poor solar energy absorption efficiency and leakage of phase change materials from PCFs seriously impaired their performance in practical applications. In this work, the core-sheath structured composite PCFs with excellent temperature regulation capability and high energy storage capacity were prepared by an economical and efficient coaxial wet spinning process for the first time. The infrared absorbers, Cs0·33WO3 (CWO), were incorporated into the hollow thermoplastic polyurethane (TPU) fibers to enhance solar energy absorption, and the paraffin wax (PW) was infused into the cavity of the composite fibers, giving rise to the formation of composite PW@TPU/CWO PCFs. The resultant PCFs showed a decrease in molten enthalpy and crystal enthalpy with the increasing of CWO contents, and the PCFs of PW@TPU/CWO5 can maintain a molten enthalpy of up to 90.47 J/g and an encapsulation rate of 69.93% that were higher than almost previous reports. The simulated house model under the coverage of PCFs fabric exhibited slight temperature variation and change rate, demonstrating the excellent heat storage and regulation capability of the as-prepared PCFs. The results show great potential applications in solar energy storage, heat storage and temperature regulation areas.

A Trimode Thermoregulatory Flexible Fibrous Membrane Designed with Hierarchical Core-Sheath Fiber Structure for Wearable Personal Thermal Management.

Advanced textiles designed for personal thermal management contribute to thermoregulation in an individual and energy-saving manner. Textiles incorporated with phase changing materials (PCMs) are capable of bridging the supply and demand for energy by absorbing and releasing latent heat. The integration of solar heating and the Joule heating function supplies multidriving resources, facilitates energy charging and storage, and expands the service time and application scenarios. Herein, we report a fibrous membrane-based textile that was developed by designing the hierarchical core-sheath fiber structure for trimode thermal management. Especially, coaxial electrospinning allows an effective encapsulation of PCMs, with high heat enthalpy density (106.9 J/g), enabling the membrane to buffer drastic temperature changes in the clothing microclimate. The favorable photothermal conversion performance renders the membrane with the high saturated temperature of 70.5 °C (1 sun), benefiting from the synergistic effect of multiple light harvesters. Moreover, a conductive coating endows the composite membrane with an admirable electrothermal conversion performance, reaching a saturated temperature of 73.8 °C (4.2 V). The flexible fibrous membranes with the integrated performance of reversible phase change, multi-source-driven heating, and energy storage present great advantages for all-day, energy-saving, and wearable individual thermal management applications.

Electrospun Core-Sheath Nanofibers with Variable Shell Thickness for Modifying Curcumin Release to Achieve a Better Antibacterial Performance.

The inefficient use of water-insoluble drugs is a major challenge in drug delivery systems. Core–sheath fibers with various shell thicknesses based on cellulose acetate (CA) were prepared by the modified triaxial electrospinning for the controlled and sustained release of the water-insoluble Chinese herbal active ingredient curcumin. The superficial morphology and internal structure of core–sheath fibers were optimized by increasing the flow rate of the middle working fluid. Although the prepared fibers were hydrophobic initially, the core–sheath structure endowed fibers with better water retention property than monolithic fibers. Core–sheath fibers had flatter sustained-release profiles than monolithic fibers, especially for thick shell layers, which had almost zero-order release for almost 60 h. The shell thickness and sustained release of drugs brought about a good antibacterial effect to materials. The control of flow rate during fiber preparation is directly related to the shell thickness of core–sheath fibers, and the shell thickness directly affects the controlled release of drugs. The fiber preparation strategy for the precise control of core–sheath structure in this work has remarkable potential for modifying water-insoluble drug release and improving its antibacterial performance.