Copper Metal-organic Framework Research Articles

Methods for the fluorescence sensing of thiamine (vitamin B1)-by copper metal organic framework and rhodamine b on graphene oxide with cucurbit[7]uril

Methods for the fluorescence sensing of thiamine (vitamin B1)-by copper metal organic framework and rhodamine b on graphene oxide with cucurbit[7]uril

Tripartite Detection and Sensing of Toxic Heavy Metals Using a Copper-Based Porphyrin Metal-Organic Framework.

The detection of heavy metals in water sources is a critical concern for environmental preservation and public health. However, current electrochemical heavy metal sensors suffer from high sensing limits, cross-sensitivity, and poor selectivity. In this work, we present the possibility of an electrochemical sensor based on a copper (Cu) metal-organic framework for the detection of lead, cadmium, and mercury by replacing Cu metal nodes. The working electrode consists of a ∼5 μm thin layer of copper- tetracarboxyphenylporphyrin (Cu-TCPP) sheets that are adsorbed on a glassy carbon electrode (GCE). Upon interaction with Pb2+, Cd2+, and Hg2+, these ions are adsorbed on and incorporated into the metal nodes of the MOF. The adsorbed metallic species can be oxidized to the ionic form (Pb → Pb2+) electrochemically, which results in an oxidation response and enables the quantitative detection of these metals. The oxidation peak currents follow a (mostly) bimodal linear regression with a sensing range of up to 30 μM dependent on the deposition time and an ultralow limit of detection (LoD) of up to 5 nM. The system displays robust and selective sensing in saturated solutions of counterions and interfering metal ions (low error margins of <10%). This work represents the first report of a Cu-TCPP-modified GCE anode as an effective electrode for the sensitive detection of multiple heavy metals and an in-depth study into the Cu replacement kinetics of the Cu-MOF.

Orchestrating a Supercapacitive Symphony: Copper–Metal Organic Framework Integrated MXene Nanosheets on Graphite Sheet Electrodes Unveiling Its Synergistic Interactions by Density Functional Theory Study

Orchestrating a Supercapacitive Symphony: Copper–Metal Organic Framework Integrated MXene Nanosheets on Graphite Sheet Electrodes Unveiling Its Synergistic Interactions by Density Functional Theory Study

Enhancing Fuel Cell Performance: The Role of a Copper Metal–Organic Framework in Phosphoric Acid-Doped Polybenzimidazole Proton Exchange Membranes

Enhancing Fuel Cell Performance: The Role of a Copper Metal–Organic Framework in Phosphoric Acid-Doped Polybenzimidazole Proton Exchange Membranes

Enhanced adsorption and regeneration performances for methyl mercaptan capture by a metal–organic framework incorporated in a mesoporous silica

Cu-modified adsorbent is widely used in removing S-containing odor pollutant, such as methyl-mercaptan (CH3SH). Increasing the dispersion of adsorptive sites and improving the regeneration cycle efficiency are two important problems. In this work, a copper metal–organic framework (MOF) was synthesized by in-situ growing the Cu-MOF on SBA-15. Micro-morphology characterizations revealed that the Cu-MOFs grew inside the SBA-15 mesopore channels and showed a good dispersion. When the hybrid (Cu-MOF in SBA-15) and the Cu-MOFs were compared for the CH3SH removal, the hybrid removed 1.70-mol CH3SH per mol of Cu in the adsorbent. This adsorbent capacity was far bigger than Cu-MOFs (0.70 mol·mol−1) and resulted from a better Cu-MOFs dispersion in SBA-15. Additionally, an easy and energy-saving hydrothermal method was put forward for the regeneration of the used adsorbent at 80 °C. The capacity of the regenerated material was higher than 70 % for at least 6 cycles. In addition, the regeneration temperature was far lower than that (> 350 °C) generally utilized in previous reports investigating cycled adsorption of CH3SH. The enhanced regeneration performances were attributed to the confinement effect of the SBA-15, which restrained the ligand around the Cu coordination centers. This work confirms the effective removal of odor-gas using a cost-effective regenerable adsorbent.

An efficient novel NiCu@INA/rGO MOF hollow microsphere Z-scheme heterojunction catalyst for the photocatalytic degradation of tetracycline and simultaneous degradation of cationic and anionic Dyes

Bimetallic metal-organic framework materials have captivated considerable attention in photocatalysis because of their colossal properties like semiconducting, large surface area, and potent visible light harnessing ability. Self-aggregation and rapid recombination rates have greatly hindered their applications in photocatalysis. A novel reduced graphene oxide-incorporated bimetallic nickel copper metal-organic framework (NiCu@INA/rGO MOF) is fabricated using isonicotinic acid as an organic linker. A synergistic effect between the two metals increased the photocatalytic performance. Introducing reduced graphene oxide to nickel-copper MOF increased charge carrier retention transfer and enhanced the catalyst’s water dispersibility. The efficiency of the photocatalyst for the removal of tetracycline (TCn) and a mixture of Rhodamine B (RhB) and Orange G (OrG) dyes was investigated under visible light. A degradation efficiency of up to 89 % for TCn and close to ∼97.8 % and 93.5 % degradation in the case of RhB and OrG dyes was observed. The studies on the photocatalytic degradation mechanism were explored by conducting radical scavenger experiments, Electron spin resonance (ESR) studies, and Mott-Schottky analysis. TCn and RhB degradation pathways were explored by mass spectral analysis of the intermediates during the photocatalytic degradation of TCn and RhB. This work provides new paradigms for the functional modification of MOF for designing efficient photocatalysis.

Nanozyme-Based Microfluidic Chip System for pH-Regulated Pretreatment and Sensitive Sensing.

Nanozymes, possessing nanomaterial properties and catalytic activities, offer great opportunities to design sensitive analytical detection systems. However, the low interference resistance of nanozymes poses a significant limitation on the precise detection of target substances. Herein, a nanozyme-based microfluidic chip system for pH-regulated pretreatment and sensitive sensing of cysteine (Cys) is reported. The copper metal-organic framework (Cu MOF) exhibits good cysteine oxidase-like activity at pH 7.0, while demonstrating excellent laccase-like activity at pH 8.0. Taking advantage of the pH-regulated enzyme-like activity, the integrated microfluidic device involving the immobilization of Cu MOF eliminates the interference of dopamine (DA) and accurately detects the target Cys. Compared with the untreated reaction system, the developed nanozyme system shows a significantly improved accuracy in detecting Cys, with an R2 value of 0.9914. This work provides an efficient method to enhance the interference resistance of nanozymes and broadens the application in sample pretreatment.

AuNPs@MoS2 functionalized copper metal organic framework for boosting electrocatalytic glucose oxidation

A novel non-enzyme glucose sensor based on functionalized copper metal–organic framework composite material, AuNPs@MoS2/Cu-MOF, was developed for rapid glucose analysis. Cu-MOF nanomaterial was prepared via a hydrothermal method, followed by the surface loading of core–shell structured AuNPs@MoS2 to synthesize AuNPs@MoS2/Cu-MOF composite material. Consequently, a novel gold nanoparticle @ molybdenum disulfide/copper metal–organic framework (AuNPs@MoS2/Cu-MOF/GCE) non-enzyme glucose sensor was constructed. Scanning electron microscopy (SEM), energy dispersive spectrometer (EDS) and X-ray powder Diffraction (XRD) was used to verify that the non-enzyme glucose sensor had been constructed effectively. Traditional electrochemical characterization methods were employed to study the electrocatalytic performance of the AuNPs@MoS2/Cu-MOF/GCE sensor and its catalytic oxidation of glucose. The experimental results demonstrated a good linear correlation between the concentration of glucose and the peak current within the range of 0.05–14.85 mM, with a detection limit of 16.7 μM. The AuNPs@MoS2/Cu-MOF/GCE sensor exhibited rapid electrochemical response to glucose (within 0.5 s), along with long-term stability and excellent selectivity. This is because Cu(II) in Cu-MOF can serve as active sites for the electrocatalytic oxidation of glucose, while the core–shell structure of AuNPs@MoS2 with excellent conductivity can lower the energy barrier in the reaction, further accelerating this catalytic reaction. The AuNPs@MoS2/Cu-MOF/GCE sensor is cost-effective, easy to operate, and suitable for accurate rapid quantification of glucose.

Synthesis of innovative Daphne mucronata extract/Cu-MOF/PVA-PVP nanofiber as high-performance anticancer and antimicrobial agent

Nanofibers’ unique physical properties include mechanical strength, compressive strength, and high specific surface area, making them highly valuable and significant. Nanofiber can be containing nano compounds such as metal nano oxides, metal–organic framework, etc., as well as plant extracts. Plant extracts have had a special place in human life since the past and used in traditional medicine. The synthesis of new nanofibers containing plant extracts and metal–organic framework was the idea that we focused on it. For this purpose, Daphne mucronata extract and copper metal–organic framework, considering the high biological properties were used. For the synthesis of Daphne mucronata extract/Cu-MOF/PVA-PVP nanofiber, electrospinning method and polyvinyl alcohol (PVA) and polyvinyl pyrrolidone (PVP) were used. The final product’s structure was examined and verified using XRD (X-Ray diffraction analysis), EDAX (Energy dispersive X-ray analysis), CHNO EA (Carbon, hydrogen, nitrogen, and oxygen elemental analysis), SEM (Scanning electron microscope images), BET (Brunauer-Emmett-Teller theory), FT-IR (Fourier transform infrared spectroscopy), contact angle (Hydrophilic properties), mechanical strength and compressive strength. The specific surface area of the synthesized nanofiber and the diameter size of the synthesized particles were observed to be area 1102 m2/g and 80 nm, respectively. High hydrophilic properties (29°), high flexural strength (17.3 N/mm2), and high compressive strength (65.7 N/mm2) were among other characteristics of the synthesized nanofiber. Biological properties of the synthesized nanoparticle, such as anti-skin cancer, anti-bacterial, and anti-fungal properties, were tested. In the anticancer study, IC50 was 21 μg/mL, and in the antimicrobial studies (antibacterial and antifungal activity), the MIC was between 2 μg/mL and 64 μg/mL. Thus, the synthesized nanofiber can be incorporated as a bioactive compound in the medical industry, such as being utilized as bioactive medical bandages after other tests have been completed.

Improving the electrocatalytic activity of the copper (II) metal-organic framework by functionalized imidazolate linker and functionalized carbon nanoparticles for detection of acyclovir

With the aim of expansion of nanocomposite materials in electrochemical sensors, the use of nanostructures as the electrode modifier has been shown to improves the kinetics of the electron transfer reactions and consequently increases the sensitivity of the sensors. So, in this study, a new electrochemical sensor was fabricated by using the nanocomposite of copper (II) metal–organic framework with functionalized imidazolate linker [Cu3(BTC)2-2-MIM] and cationic functionalized carbon nanoparticles (CFCNPs) at the glassy carbon electrode (GCE); Cu3(BTC)2-2-MIM/CFCNPs/GCE. The as prepared nanocomposite; Cu3(BTC)2-2-MIM/CFCNPs was characterized using various instrumental techniques. To identify the capabilities and electrocatalytic activity of the synthesized nanocomposite in analytical chemistry, it was used as an electrochemical modifier along with suitable electrochemical techniques. In this regard, the prepared modified electrode; Cu3(BTC)2-2-MIM/CFCNPs/GCE was utilized to the electrooxidation and determination of the acyclovir (ACR) in NaOH solution. Under optimal experimental conditions, the Cu3(BTC)2-2-MIM/CFCNPs/GCE showed low detection limit (0.24 µM) over the concentration ranges of 2.49–84.28 μM of ACR. On the other hand, the present sensor has robust stability, good reproducibility, high selectivity and sensitivity (5.907 µAµM−1 cm−2) in electrodetermination of ACR. Also, the diffusion coefficient of ACR (DACR = 9.25 × 10−6 cm2 s−1), the transfer coefficient (α = 0.34) and catalytic rate constant (kcat = 10.1 × 105 cm3 mol−1 s−1) of ACR electrooxidation reaction were estimated at the surface of modified electrode in NaOH solution. Finally, the Cu3(BTC)2-2-MIM/CFCNPs/GCE was applied as a promising and low-cost sensor for determination of the ACR in actual pharmaceutical formulations and biological samples.

Superlong Metal-Organic Framework Nanowire Fabricated via Steam-Assisted Conversion.

1D nanomaterials have attracted great attention due to their outstanding anisotropic and linear structures. A facile method is developed to fabricate 1D copper metal-organic framework nanowires (Cu-MOF-NW) through steam-assisted conversion from Cu-MOF precursors. During the steam-assisted conversion, Cu-MOF precursor gradually dissolves in methanol steam, and then recrystallized into Cu-MOF-NW, which shows high aspect ratio of about 600 and identical crystal structure of MOF-74. As-prepared Cu-MOF-NW with multiscale porous structure can effectively remove cationic dyes even in dye mixture. Moreover, Cu-MOF-NW, as an ideal template, is calcined to form Cu nanoparticle-doped carbon nanofiber with maintaining its 1D morphology, which shows excellent electrocatalytic activity for the non-enzymatic sensing of glucose.

Construction of N-doped copper metal–organic frameworks for promoting photocatalytic carbon dioxide reduction to ethylene

Construction of N-doped copper metal–organic frameworks for promoting photocatalytic carbon dioxide reduction to ethylene

Functionalization of a porous copper(ii) metal-organic framework and its capacity for loading and delivery of ibuprofen.

A porous copper(ii) metal-organic framework (MOF) of 4,4',4''-tri-tert-butyl-2,2':6',2''-terpyridine(N3ttb) and 5-nitroisophthalic acid (npd) formulated as [Cu(npd)(N3ttb)]·(DMF)(H2O) 1 (DMF = dimethylformamide) was synthesized and characterized by elemental analyses, spectroscopic techniques, single crystal X-ray crystallography, and scanning electron microscopy. Single crystal X-ray crystallographic analysis of the copper(ii) metal-organic framework reveals a monoclinic crystal system with space group P21/c. The copper(ii) ion is in a five-coordinate geometry consisting of three meridional nitrogen atoms of 4,4',4''-tri-tert-butyl-2,2':6',2''-terpyridine and two oxygen atoms of 5-nitroisophthalic acid to form a square pyramidal structure. The compound was functionalized with ethylenediamine (ED) to form [Cu(npd)(N3ttb)]-ED 2 that was characterized by FT-IR, PXRD, SEM-EDX and BET and the drug loading capacity was investigated and compared with that of as-synthesized MOFs. The amount of ibuprofen loaded was 916.44 mg g-1 (15.27%) & 1530.20 mg g-1 (25.50%) over 1 and 2, respectively. The results indicate that the functionalized MOFs 2 have a higher loading capacity for ibuprofen than 1 by 613.76 mg g-1 (10.23%), which could be ascribed to the acid-base interactions in the functionalized molecules. The results show that [Cu(npd)(N3ttb)]-ED 2 is a better drug transporter than [Cu(npd)(N3ttb)]·(DMF)(H2O) 1 due to the presence of an amine functional group that interacts with the acid group on the ibuprofen through non-covalent bonds interactions.

Copper-MOF and tannic acid-empowered composite cryogel as a skin substitute for accelerated deep wound healing

The effective management of deep skin wounds remains a significant healthcare challenge that often deteriorates with bacterial infection, oxidative stress, tissue necrosis, and excessive production of wound exudate. Current medical approaches, including traditional wound dressing materials, cannot effectively address these issues. There is a great need to engineer advanced and multifunctional wound dressings to address this multifaceted problem effectively. Herein, a rationally designed composite cryogel composed of a Copper Metal-Organic Framework (Cu-MOF), tannic acid (TA), polyvinyl alcohol (PVA), and zein protein has been developed by freeze-thaw technique. Cryogels display a remarkable swelling capacity attributed to their interconnected microporous morphology. Moreover, dynamic mechanical behaviour with the characteristics of potent antimicrobial, antioxidant, and biodegradation makes it a desirable wound dressing material. It was further confirmed that the material is highly biocompatible and can release TA and copper ions in a controlled manner. In-vivo skin irritation in a rat model demonstrated that composite cryogel did not provoke any irritation/inflammation when applied to the skin of a healthy recipient. In a deep wound model, the composite cryogel significantly accelerates the wound healing rate. These findings highlight the multifunctional nature of composite cryogels and their promising potential for clinical applications as advanced wound dressings.

Graphene oxide/Cu–MOF-based electrochemical immunosensor for the simultaneous detection of Mycoplasma pneumoniae and Legionella pneumophila antigens in water

The combination of copper–metal organic framework (Cu–MOF) with graphene oxide (GO) has received growing interest in electrocatalysis, energy storage and sensing applications. However, its potential as an electrochemical biosensing platform remains largely unexplored. In this study, we introduce the synthesis of GO/Cu–MOF nanocomposite and its application in the simultaneous detection of two biomarkers associated with lower respiratory infections, marking the first instance of its use in this capacity. The physicochemical properties and structural elucidation of this composite were studied with the support of XRD, FTIR, SEM and electrochemical techniques. The immunosensor was fabricated by drop casting the nanocomposite on dual screen-printed electrodes followed by functionalization with pyrene linker. The covalent immobilization of the monoclonal antibodies of the bacterial antigens of Mycoplasma pneumoniae (M. pneumoniae; M. p.) and Legionella pneumophila (L. pneumophila; L. p.) was achieved using EDC-NHS chemistry. The differential pulse voltammetry (DPV) signals of the developed immunosensor platform demonstrated a robust correlation across a broad concentration range from 1 pg/mL to 100 ng/mL. The immunosensor platform has shown high degree of selectivity against antigens for various respiratory pathogens. Moreover, the dual immunosensor was successfully applied for the detection of M. pneumoniae and L. pneumophila antigens in spiked water samples showing excellent recovery percentages. We attribute the high sensitivity of the immunosensor to the enhanced electrocatalytic characteristics, stability and conductivity of the GO–MOF composite as well as the synergistic interactions between the GO and MOF. This immunosensor offers a swift analytical response, simplicity in fabrication and instrumentation, rendering it an appealing platform for the on-field monitoring of pathogens in environmental samples.

Development of ternary hybrid composites of transition metal and noble metal-based heterostructures: Ultrasensitive simultaneous electrochemical detection of bisphenol A and bisphenol S in food samples

Bisphenols threaten human health and sensitive detection is crucial. The present study aims to develop ternary composites of copper metal-organic framework (Cu-MOF) with AuAg microstructures. The composite structure was formed by a galvanic displacement reaction and confirmed using SEM. A binder-free catalyst was used to study the electrochemical redox reaction of bisphenol A (BPA) and bisphenol S (BPS); an irreversible cyclic voltammetric signal at +0.70 V and + 0.91 V (vs. Ag/AgCl), in the dynamic range of 20 nM to 2.0 mM, and 10 nM to 1.0 mM, with limits of detection of 2.9 nM, and 3.2 nM (S/N = 3) was obtained. Practical analysis was applied to frozen tomatoes, tuna fish, milk powder, PET bottles, raw milk, and urine samples with a recovery rate of 94.00–100.80% (n = 3). Voltammetric results were validated using HPLC detection with high precision. The sensor is a promising alternative platform for measuring BPA in food samples.

Copper metal-organic framework for selective detection of florfenicol based on fluorescence sensing in chicken meat

Using a hydrothermal technique, a highly sensitive metal-organic Cu-MOFs sensor has been created to detect florfenicol (FFC) fluorescent in chicken meat. The sensor has demonstrated the ability to respond to the presence of FFC in an aqueous solution with accuracy and selectivity, as evidenced by an increase in fluorescence intensity. The interactions and adsorption mechanism based on hydrogen bonding, π- π, and n-π interactions demonstrate the high sensitivity and specificity of Cu-MOFs towards. FFC was detected quantitatively with a recovery of 96.48–98.79% in chicken meat samples. Within a broad linear range of 1–50 μM, the Cu-MOFs nanosensor exhibits a fast response time of 1 min, a low limit of detection (LOD) of 2.93 μM, and a limit of quantification (LOQ) of 8.80 μM. The potential applicability of the Cu-MOFs nanosensor for the detection of FFC in food matrices is confirmed by the results obtained with high-performance liquid chromatography (HPLC). Chemical compoundsCopper (II) nitrate (PubChem CID: 18616); Terephthalic acid (PubChem CID: 7489); Polyvinyl pyrrolidone (PubChem CID: 486422059); N, N-dimethylformamide (PubChem CID: 6228); Ethyl alcohol (PubChem CID: 702); Hydrochloric acid (PubChem CID: 313); Sodium hydroxide (PubChem CID: 14798); Acetic acid (PubChem CID: 176); Trichloroacetic acid (PubChem CID: 6421); Florfenicol (PubChem CID: 114811).

Reinforced MOF/polymer composite based on a copper metal-organic framework supported on nanoporous hyper cross-linked polycalix[4]resorcinarene for the preparation of phthalazine and 4H-pyran heterocycles

The present study has aimed to prepare a novel MOF/polymer composite called PC4RA@PrSi-CA/Cu-MOF to take benefit from the advantages of both Cu-based metal-organic framework (Cu-MOF) and porous polymer based on Cis-calix[4]resorcinarene (PC4RA). Various processes, including preparation of a 3D network of polycalix, modification of polycalix with (3-aminopropyl)trimethoxysilan (APTMS) and citric anhydride (CA), and functionalization of the modified polymer with Cu-MOF nanostructure, respectively, were used for synthesizing MOF/polymer composite. Next, the characterization and confirmation of the polymer-supported Cu-MOF were analyzed using FT-IR, EDS-Mapping, STA, PXRD, FE-SEM, and TEM techniques. In the continuation, two types of heterocycles, including phthalazines and 4H-pyrans, were synthesized to reveal the efficiency of the PC4RA@PrSi-CA/Cu-MOF nanocomposite. The catalyst showed a reasonable performance by providing a satisfactory yield of the desired products (90–99 %) during a short time (8–20 min) under mild and green conditions (50 °C in H2O). Furthermore, the structure of the heterocycles was validated using FT-IR, 1H/13C NMR. Then, the catalyst was successively reused ten times in the model reaction and studied using FT-IR, EDX, TEM, and elemental mapping analyses to demonstrate the catalyst stability in recoverability. According to the results, this heterogenized catalyst can recover several times without a notable drop in stability and activity.

Sonochemical-assisted method for efficient synthesis of Cu-MOF and evaluating its antibacterial properties

Sonochemical-assisted method was used to synthesize copper metal-organic frameworks (Cu-MOF) nanostructures. The final products were examined by related techniques such as XRD patterns, SEM image, BET N2 adsorption/desorption technique and FTIR spectrum. Microtiter plates microbiological assay were used to investigate antibacterial properties and the results were analyzed using ANOVA and Tukey HSD tests. The results showed that Cu-MOF nanostructures have a mesoporous nature with an average particle size distribution around 60 nm. The final product had the property of preventing the growth of all tested bacteria in certain concentrations. Minimum Inhibitory Concentration (MIC) values were observed in the range of 30–100 ppm. It was also discovered that this nanostructure can not kill bacteria completely. In addition, the minimal inhibitory concentration for biofilm growth (MIC-B) of the nanostructure was investigated. The MIC-B analyzes demonstrated that the growth of bacterial biofilm decreased with increasing Cu-MOF concentration.

Insights into the Degradation and Mechanism of the Enhanced Persulfate Degradation of Tetracycline using an Efficient 3D Copper Metal–Organic Frameworks

Insights into the Degradation and Mechanism of the Enhanced Persulfate Degradation of Tetracycline using an Efficient 3D Copper Metal–Organic Frameworks