Background: The caregivers are vulnerable to develop depression and anxiety due to increased workload and multiple stressors associated with care giving role. The understanding of coping strategies among caregivers of children with autism and normal would offer a comprehensive understanding of mental health of caregivers and coping strategies can offer protective and remedial mechanism. Objective: The present study investigated the differences in Mental Well Being and Coping Strategies of caregivers of children with Autism and Normal children. Sample: The sample size comprised of thirty caregivers of children with Autism and thirty caregivers of normal children. Tools Used: The tools used for data collection was Warwick Edinburgh Mental Well-Being Scale (WEMWBS) the Coping Strategies scale. Result: Results indicated the significant differences in Approach Behavioural coping strategy among Caregivers of Autistic children group and Caregivers of Normal Group. However, no significant differences between Mental Well Being and Approach Cognitive Coping Strategies of Caregivers of children with Autism and Caregiver group of Normal children.