Abstract This study sought to identify the most accurate forecasting models for COVID-19-confirmed cases, deaths, and recovered patients in Pakistan. For COVID-19, time series data are available from 16 April to 15 August 2021 from the Ministry of National Health Services Regulation and Coordination’s health advice portal. Descriptive as well as time series models, autoregressive integrated moving average, exponential smoothing models (Brown, Holt, and Winters), neural networks, and Error, Trend, Seasonal (ETS) models were applied. The analysis was carried out using the R coding language. The descriptive analysis shows that the average number of confirmed cases, COVID-19-related deaths, and recovered patients reported each day were 2,916, 69.43, and 2,772, respectively. The highest number of COVID-19 confirmed cases and fatalities per day, however, were recorded on April 17, 2021 and April 27, 2021, respectively. ETS (M, N, M), neural network, nonlinear autoregressive (NNAR) (3, 1, 2), and NNAR (8, 1, 4) forecasting models were found to be the best among all other competing models for the reported confirmed cases, deaths, and recovered patients, respectively. COVID-19-confirmed outbreaks, deaths, and recovered patients were predicted to rise on average by around 0.75, 5.08, and 19.11% daily. These statistical results will serve as a guide for disease management and control.