Large flow and long distance intersections are very difficult to bring out coordination control and very easy to emerge traffic problems such as traffic congestion due to the large flow and long distance and traffic discrete. It’s necessary to analysis the traffic flow characteristics among large flow and long distance intersections and take measure to improve the signal control. This paper analyzed the traffic flow characteristics of the large flow and long distance intersections, such as the speed would be faster than the normal road between near distance intersection, the headway between cars would be increased, and long traffic queue would be easily occurred at the downstream intersection. In order to realize the coordination control between far intersections, measures for example puts forward signal light at an appropriate position between the intersections, set up fences between vehicles and bicycles, and intersection channelized were put forward to rebuild the traffic flow to adjust the signal control. Those measures were applied to the intersections in Danyang which located in Jiangsu province, the results shows that the queue length was reduced by 67.4% at downstream intersection, the average delay was reduced by 60.3%, the traffic flow saturation was reduced to0.67, and the travel speed and travel time would all become better than before. It suggested that those methods could realize the coordination control and its effect was good, and have good feasibility and practicability.