Conversion Of Cyclohexane Research Articles

The Effect of Crown Ethers and Polyglycols on the Sustainability Indicators of Cyclohexane Oxidation Process

The crown ether or polyglycol additives to transition metal catalysts improve both the performance indicators, such as cyclohexane conversion, selectivity of target products, and the sustainability indicators of the oxidation process. It has been shown that the effect of the organic additives on the sustainability indicators is primarily due to a significant (up to 14.3%) increase in the selectivity of target cyclohexane oxidation products.

Highly selective aerobic oxidation of cyclohexane by flower-like MoO3-x microspheres-nitrogen-doped carbon dots heterojunction

Due to the higher susceptibility of alcohols and ketones to oxidation compared to alkanes, converting inert C-H bonds in alkanes into high value-added product KA oil with high selectivity is still a significant obstacle. In this study, flower-like microspheres of MoO3-x, featuring aligned nanosheets and oxygen vacancies, were combined with nitrogen doped carbon dots (NCDs) to fabricate S-scheme heterojunctions of MoO3-x-NCDs for boosting the photocatalytic efficiency in oxidizing cyclohexane. Because of the oxygen vacancies-triggered localized surface plasmon resonance (LSPR) and the S-scheme charge transfer mechanism, there was a significant improvement in the absorption of visible light and an enhancement in the efficiency of charge separation. The MoO3-x-NCDs composites exhibited a notably improved catalytic performance in cyclohexane oxidation. The MoO3-x-NCDs composite exhibited remarkable selectivity of KA oil in catalyzing cyclohexane oxidation under light exposure, attributed to the substantial increase in cyclohexane adsorption capacity. The highest cyclohexane transformation rate of 9.98 % was achieved by MoO3-x-NCDs-2 composites with a MoO3-x/NCDs ratio of 50:1, outperforming bare MoO3-x by 1.81 times, while exhibiting a KA oil selectivity reaching 93.75 %. The mechanism of selective photocatalytic oxidation was explored using photoelectric examination, analysis of energy bands, and evaluation of active radicals. In this research, green photocatalysts were fabricated through the utilization of NCDs, enabling efficient conversion and selective oxidation of cyclohexane in gentle environments. This innovative approach holds great potential for advancing the field of photocatalysis.

Constructing homo/hetero-nuclear carbon and oxygen atoms co-doped graphitic carbon nitride assisted by ionic liquid for photothermal synergistic catalytic oxidation of cyclohexane

The adoption of photothermal synergistic catalysis for cyclohexane oxidation can balance the advantages of high conversion of thermal catalysis and high selectivity of photocatalytic technology to achieve better catalytic performance. Here, we prepared functional carbon nitride (BCA-CN) by self-assembly strategy of ionic liquid [Bmim]CA (1-Butyl-3-methylimidazole citrate) with melamine and cyanuric acid utilizing abundant elements and anionic/cationic hydrogen bonding interactions. The introduction of [Bmim]CA embeds C-C (carbon and carbon band) and C-O-C (ether bond) structures into graphitic carbon nitride (g-C3N4) framework, significantly improving light absorption capacity and migration of photo generated charge carriers. Compared to g-C3N4, both BCA-CN increases cyclohexane conversion and KA oil (the mixture of cyclohexanol and cyclohexanone) selectivity by 1.3 times under photothermal catalysis. The surface reactions are facilitated by changing adsorption sites of cyclohexane to increase adsorption energy and obtaining more hydroxyl radicals and superoxide radicals. Furthermore, the enhanced selectivity is attributed to the difficulty in generating cyclohexanone radicals. This work offers the reference scheme for the development of efficient photothermal catalysts in the selective oxidation of cyclohexane.

Studies on the Selectivity Between O-Alkylation versus C-Alkylation of Phenol with Cyclohexene Using Nanocrystalline Beta Zeolite

The alkylation of phenol with cyclohexene using acid catalysts results in the generation of both O-alkylated and C-alkylated products, all of which hold significant utility across diverse industries. Cyclohexyl phenyl ether is utilized as a fragrant compound in perfumery applications. Through dehydrogenation, it transforms into diphenyl oxide (DPO), a significant chemical intermediate. In the current research nanocrystalline zeolite Beta was synthesised by vacuum-concentration coupled hydrothermal technique using tetraethyllammonium hydroxide templates and the catalytic performance was analysed for the alkylation of phenol with cyclohexene. Various parameters like reactant mole ratio, catalyst amount and temperature were assessed for better conversion of cyclohexene and desired product selectivity. The findings demonstrate that the catalyst effectively improves the conversion of cyclohexene while enhancing the selectivity of desired products. High efficiency of the catalyst is attributed due to its favourable structural characteristics, including its nano sized particles with open pore structure. The catalyst displayed up to ~96% conversion of cyclohexene ~55% selectivity towards the major product, cyclohexyl phenyl ether at optimal reaction conditions. Activation energy of the phenol alkylation with cyclohexene was calculated from the measured rate constant at various temperatures and was found to be 22.9 kJ/mol. There is negligible decline in percent conversion after reusing the catalyst for up to five runs.

Efficient allylic oxidation of cyclohexene catalyzed by Ti-MCM-41 using H2O2 as oxidant

2-cyclohexen-1-ol and 2-cyclohexen-1-one are very important chemical raw materials, and it is a challenge to develop an environmental and efficient synthesis route with titanium-containing catalyst to obtain high yield of allylic oxidation product. Herein, we present an intensive study on the allylic oxidation of cyclohexene over titanosilicates/H2O2 system. Ti-MCM-41 is found as an efficient catalyst. The reaction parameters, including cyclohexene/H2O2 molar ratios, solvent, catalyst amount, titanium content, reaction temperature and reaction time, were studied in detail. And a high cyclohexene conversion (∼20.2 %) and total selectivity of 2-cyclohexen-1-one and 2-cyclohexen-1-ol (∼90.0 %) was achieved under optimized reaction conditions. Further the allylic oxidation of cyclohexene proceeds a radical mechanism as demonstrated by the addition of radical scavenger BHT. This will make it possible for the highly selective green generation of enols and ketenes.

Stable Pt/MgAl2O4 catalysts for efficient production of H2 from cyclohexane dehydrogenation

Cyclohexane as liquid organic hydrogen carriers has attracted considerable interest in the field of hydrogen storage technology. However, the innovation of efficient catalyst for producing H2 through cyclohexane dehydrogenation remains a substantial challenge. In this study, we have successfully developed Pt/MgAl2O4 catalysts exhibiting outstanding catalytic performance in cyclohexane dehydrogenation. Notably, the optimal catalyst Pt/MgAl2O4-700 achieves cyclohexane conversion of 89.1 % and benzene selectivity of over 99 % at 345 °C, resulting in a high hydrogen evolution rate of 933 mmol/gPt/min. Moreover, this catalyst exhibits remarkable long-term stability, with no evident loss of activity in 225-hour dehydrogenation reaction. The catalyst was characterized by XRD, N2 adsorption–desorption, STEM, XPS, NH3-TPD, CO-FTIR and H2-TPR techniques, which provides detailed structure information for elucidation of structure–activity relationship. The spinel structure and moderate acid density of the support enable highly dispersed Pt species at the surface of MgAl2O4. This results in the formation of ultra-small and sintering-resistant Pt particles that exhibit exceptional activity in cyclohexane dehydrogenation. Additionally, the presence of positively charged Ptδ+ species in Pt/MgAl2O4 facilitates the rapid desorption of benzene product. This effectively prevents the formation of coke arising from benzene dehydrogenation, which ensures to achieve high stability. These findings provide valuable knowledge for the rational design of efficient metal-based catalysts for liquid organic hydrogen carriers in hydrogen storage systems.

Selective Oxidation of Cyclohexene over the Mesoporous H-Beta Zeolite on Copper/Nickel Bimetal Catalyst in Continuous Reactor.

The copper/nickel-metal on commercial H-Beta zeolite supports was synthesized with different wt % (Ni) of 5, 10, 15, and 20, and was used in the cyclohexene epoxidation process. The synthesized catalyst has been used in a continuous reactor for the cyclohexene epoxidation process, with mild conditions and H2O2 as an oxidant. The catalytic performance was ascertained by adjusting parameters such as the temperature, pressure, WHSV, reaction time, and solvents. The catalytic performance showed the resulting yield in both cyclohexene conversion and selectivity was more than 98.5%. The catalyst's textural attributes, morphology, chemical composition, and stability were determined using FT-IR, XRD, BET, HR-SEM, and TPD. The most active catalyst among those that were synthesized was evaluated, and the reaction parameters were selected to optimize yield and conversion. The H-Beta/Cu/Ni (15%) catalyst has the best conversion (98.5%) and selectivity (100%) for cyclohexene among the catalysts examined. Cu and Ni(15%) metals were successfully added to the H-Beta zeolite, causing little damage to the crystalline structure and resulting in good reusability over five cycles, as well as little loss of catalytic selectivity. Acetonitrile was the solvent that provided the highest conversion and selectivity among the others. These findings show that H-Beta/Cu/Ni bimetallic catalysts have the potential to be effective epoxidation catalysts. Because of their outstanding conversion and selectivity, the continuous reaction technique used in this work makes them appropriate for industrial production-level applications.

Interfacial hydrogen bond effect between CeO2 and g-C3N4 boosts conversion to adipic acid from aerobic oxidation of cyclohexane

The selective oxidation reaction of cyclohexane is one of the typical activated sp3 C-H reactions, and its product adipic acid (AA) is the indispensable raw material used to produce nylon. However, subjecting to the inertness of C-H bond and the great reactivity of AA, the targeted transformation of cyclohexane remains a challenge. Here, the interfacial hydrogen bond (IHD) was developed by anchoring CeO2 on graphite carbon nitride (g-C3N4) surface, which could boost targeted acquisition adipic acid from aerobic oxidation of cyclohexane. The results indicated that the IHD effect can be flexibly regulated by changing the ratio of Ce3+/Ce4+, further optimizing the properties of surface OH species and Lewis acid sites. Under the synergistic effect of Ce3+/Ce4+ and Lewis acid sites on reaction interface, the glorious performance (32.2% conversion of cyclohexane with 66.4% selectivity) was obtained over the as-prepared CeO2/g-C3N4 IHD system. In addition, the interfacial adsorption properties of cyclohexane were explored by the virtue of in situ infrared spectroscopy, revealing the IHD effect could tune the adsorption behavior of cyclohexanone and further improve the selectivity of AA. This work disclosed that engineering the interface hydrogen bond effect between CeO2 and g-C3N4 provided feasible strategies to obtain excellent catalyst for cyclohexane oxidation.

High-electrophilic (SiO)2Nb(OH)(=O) sites confined in silanol defects over Nb-Beta zeolite for efficient cyclic alkene epoxidation reactions

Dealuminated Beta zeolite has a large amount of silanol defects on its interface, which provides an ideal place for embedding metal species and creating metal active sites in a confined microenvironment. The confined metal sites as well as their surroundings are closely related to the reactant activation and transient state achievement. Hence, unraveling the confined metal sites is of great significance for the catalytic reaction process. Herein, niobium species were incorporated into the silanol defects over dealuminated Beta zeolite with a facile dry impregnation method, co-grinding the niobium precursor with dealuminated Beta zeolite support. The successful incorporation of niobium into the silanol defects for 30Nb-Beta zeolite was verified by DRIFT, 1H MAS NMR, UV–Vis and UV-Raman characterizations. XAS characterization and DFT calculations further disclosed that the confined Nb species existed as (SiO)2Nb(OH)(=O), containing two Si−O−Nb bonds, one Nb=O bond as well as one Nb−OH bond. The synthesized 30Nb-Beta zeolite catalyst displayed a superior cyclohexene conversion of 51.1%, cyclohexene oxide selectivity of 83.1% as well as TOF value of 188.2 h−1 ascribed to the inherent electrophilicity of Nb(V) for confined (SiO)2Nb(OH)(=O) species as well as the low oxygen transfer energy barrier for NbV−OOH species. Furthermore, the prepared 30Nb-Beta zeolite can be effectively employed to other cyclic alkene epoxidation reactions.

Prussian Blue Analogue-Derived Co3O4 as Catalysts for Enhanced Selective Oxidation of Cyclohexane Using Molecular Oxygen.

Selective conversion of inert C-H bonds in alkanes into high-value-added functional groups (alcohols, ketones, carboxylic acids, etc.) plays a vital role in establishing a green and sustainable chemical industry. Catalytic selective oxidation of cyclohexane to KA oil (cyclohexanol and cyclohexanone) is a typical representative of alkane functionalization. In this work, hollow cage-like Co3O4 (Co3O4-C) and particle Co3O4 (Co3O4-P) were synthesized by calcining two types of Prussian blue analogues (PBAs), which were used to catalyze the selective oxidation of cyclohexane. The Co3O4-C predominantly exposed (311) crystal plane is easier to adsorb cyclohexane than Co3O4-P, which is beneficial to shorten the induction period, accelerate the reaction rate, and improve the conversion. Consequently, Co3O4-C displayed a 10% conversion of cyclohexane within 1 h, and the KA oil selectivity reached 90%. The Co3O4-P exposed (220) crystal plane has a higher molar percentage of oxygen vacancies and more active oxygen species, as well as a strong cyclohexanone adsorption capacity, which is conducive to the deep oxidation of cyclohexanone to adipic acid and other diacid products. The mechanism analysis of cyclohexane oxidation catalyzed by PBA-based Co3O4 shows that it exemplifies the feasibility to tailor the surface of catalysts by modulating the PBAs, which ultimately influences their reaction performance for accelerating the reaction and maintaining high cyclohexane conversion and KA oil selectivity.

Reversible hydrogenation and dehydrogenation of benzene for hydrogen storage on highly dispersed Pd/γ-Al2O3 catalyst

The research and development of efficient catalyst is the key to achieving high-capacity hydrogen storage in liquid organic hydrogen carriers (LOHCs). The highly dispersed Pd/γ-Al2O3 catalysts with few-atom Pd were prepared by impregnation method using HNO3 as promoter. The hydrogen storage capacity of the benzene/cyclohexane hydrogen carriers was further investigated by vapor phase benzene hydrogenation and cyclohexane dehydrogenation reactions over the studied Pd/γ-Al2O3 catalysts. The results showed that the metal Pd was the active centers for the benzene hydrogenation/cyclohexane dehydrogenation reactions. The addition of HNO3 can effectively promote the metal Pd to be highly dispersed, thus improving the Pd atoms utilization and reducing the Pd dosage. Meanwhile, the strongly electronic effects between the highly dispersed Pd species and the Al2O3 support promoted the electron-deficient Pdδ+ sites to be formed, which enhanced the adsorption and activation ability for the reactants molecules. The benzene conversion on the Pd/γ-Al2O3 catalyst with a metallic Pd loading of 1.0 wt% reached 97.51 % at 200 °C. While the cyclohexane conversion reached 90.94 % at 400 °C with the actual hydrogen storage capacity of 6.54 wt%, which provided an effective idea for large-scale storage and transportation of H2 based on LOHCs.

Hydrogenation of cyclohexene over single-atom Pt or Pd incorporated porous ceria nanoparticles under solvent-free conditions.

In order to maximize the utilization of noble metals in catalysis, single atom of palladium (Pd) and platinum (Pt) were incorporated individually in the framework of porous ceria (CeO2) by using a one-step flash combustion method. Samples with different Pd and Pt loading (0.5, 1, 2.5, and 5 wt%) were prepared and examined by using different analysis techniques such as XRD, ICP, N2 sorption measurements, SEM, HR-TEM, and XPS. The characterization data confirms the formation of zero-state single-atom Pt and Pd (with possible formation of Pd nanoparticles with a size less than 5 nm) incorporated onto the three-dimensional porous ceria structure. The catalytic activity of the synthesized materials was studied in the cyclohexene reduction to cyclohexane at 393 K and 3 atm of pure hydrogen (H2) gas as a model reaction. The obtained results demonstrated that the conversion percentage of cyclohexene is increasing with Pd or Pt loading. The best cyclohexene conversion, 21% and 29%, was achieved over the sample that contains 5 wt% of Pt and Pd, respectively. The collected catalytic data fit the zero-order reaction model, and the rate constant of each catalyst was determined. The catalytic experiments of the most-performed catalysts were repeated five times and the obtained loss in activity was insignificant.

Synthesis and characterization of mesoporous silica supported metallosalphen-azobenzene complexes: efficient photochromic heterogeneous catalysts for the oxidation of cyclohexane to produce KA oil.

The oxidation of cyclohexane to produce KA oil (cyclohexanone and cyclohexanol) is important industrially but faces challenges such as low cyclohexane conversion at high KA oil selectivity, and difficult catalyst recyclability. This work reports the synthesis and evaluation of new heterogeneous catalysts consisting of Co(ii), Mn(ii), Ni(ii) and Cu(ii) salphen-azobenzene complexes [ML1] immobilized on amino-functionalized mesoporous silica (SBA-15, MCM-41, MCM-48) through coordination bonding. In the first step, the salphen-azobenzene ligand was synthesized and complexed with Co, Mn, Ni and Cu metal ions. In the second step, aminopropyltriethoxysilane (APTES) was grafted onto the surface of different types of commercial mesoporous silica. The immobilization of [ML1] onto the mesoporous silica surface and the thermal stability of the obtained materials were confirmed using different characterization techniques such as FT-IR, powder XRD, SEM, TEM, BET, and TGA. The obtained results revealed high dispersion of [ML1] through the silica surface. The catalytic activity of the prepared materials Silica-N-ML1 was evaluated on the cyclohexane oxidation to produce KA oil using various oxidants. The cis-trans isomerization of the azobenzene upon UV irradiation was found to affect the catalytic performance of Silica-N-ML1. The cis isomer of SBA-15-N-CoL1 exhibited the highest cyclohexane conversion (93%) and KA selectivity (92%) under mild conditions (60 °C, 6 h) using m-CPBA as oxidant. Moreover, The SBA-15-N-CoL1 showed high stability during four successive cycles.

An extremely electron poor Au(III) trication bearing acetonitrile ligands.

The synthesis and structural characterization of an electron poor Au(III) trication bearing 2 imidazole and 2 acetonitrile ligands is described. The new complex is capable of aryl C-H metalation with the formation of a monomesitylene complex and also demonstrated to be highly oxidizing in the rapid room temperature conversion of cyclohexene to benzene.

Fabrication of single Co sites in graphitic carbon nitride via the ion exchange to boost aerobic cyclohexane oxidation

Cyclohexane oxidation is an industrial process for manufacturing cyclohexanol, cyclohexanone and adipic acid, while it remains a huge challenge to develop highly efficient catalysts for intensifying this process. Herein, a bottom-up synthesis approach, coupling the one-pot and ion exchange strategy, is developed to fabricate atomically dispersed Co on graphitic carbon nitride (g-C3N4) for the aerobic cyclohexane oxidation. The loading of the single-atom Co on Co/g-C3N4 can be facilely tuned by adjusting the ion exchange extent of Na + on Na/g-C3N4 precursor. Comprehensive characterizations demonstrate the atomical location of Co in sixfold cavities of g-C3N4, accompanied by the electron interaction between Co atoms and g-C3N4. The resulting Co/g–C3N4–1 catalyst possesses the superior oxidation performance with the 28.8 % cyclohexane conversion and 93.0 % overall selectivity toward desired products, and it also exhibits an acceptable universality to the catalytic oxidation of various hydrocarbons. The mechanism study revealed that besides the dissociation of O2 molecules on single-atom Co sites, the electron-rich g-C3N4 surface stemming from atomic Co doping facilitated the cyclohexane adsorption, which synergically boosted the subsequent oxidation reaction following the surface catalytic mechanism. We anticipate that such a concept of fabricating atomically dispersed metals via the ion exchange strategy provides a novel insight and feasible approach for the design of highly efficient single-atom catalysts for the cyclohexane oxidation and beyond.

Defect‐induced Synthesis of Highly Dispersed Hydroxyapatite‐Supported Vanadium Oxide for the Oxidative Dehydrogenation of Cyclohexane

AbstractHydroxyapatite (HAP) contains abundant defect sites and easily releases hydroxyl groups to produce new vacancies under calcination at high temperature. The highly dispersed VOx/HAP catalyst was prepared by an impregnation method using these defects as inducement. VOx species with different structures were analysed by XRD, XPS, H2‐TPR, Raman and UV–vis spectroscopy. At low calcination temperatures (500 °C and 600 °C), the V species are mainly V2O5 crystals. At high calcination temperatures (above 700 °C), VOx on the HAP surface fills these defect sites and strongly interacts with HAP to form Ca−O−V or P−O−V bands. These scattered defects improved the dispersion of V species. These highly dispersed VOx/HAP catalysts were used for oxidative dehydrogenation (ODH) of cyclohexane to cyclohexene. The highly dispersed VOx/HAP catalyst showed a high selectivity for cyclohexene, and the selectivity reached 48.2 % when the conversion of cyclohexane was 13.1 % at 410 °C.

Mesoporous Beta zeolites with controlled distribution of Brønsted acid sites for alkylation of benzene with cyclohexene

The distribution of Brønsted acid sites in three-dimensional 12-membered pore channels of Beta zeolite was a decisive factor in the alkylation of benzene with cyclohexene. Here, the Brønsted acid site distribution in Beta zeolitic channels was precisely regulated by tuning the content of Na+ in crystallization system combined with tetraethylammonium cation, the Beta-55 with Brønsted acid sites exclusively located in straight channels (along a- and b-axis directions) was successfully synthesized by utilizing tetraethylammonium as the structure-directing agents without Na+ species, and the fraction of Brønsted acid sites in sinusoidal/straight channels of Beta zeolites can be accurately controlled by tailoring the content of Na+ in synthesis gel. Catalytic properties in the liquid alkylation between benzene and cyclohexene exhibited that Beta-55 zeolites with the Brønsted acid sites solely located in a-axis and b-axis channels showed the highest cyclohexene conversion, cyclohexylbenzene selectivity and longest lifetime in this reaction. In addition, the resultant Beta zeolites also exhibited low coke generation rate and robust regeneration performance in the alkylation reaction.

The catalytic activity of copper/nickel supported on mesoporous aluminum catalyst towards cyclohexene epoxidation in continuous reactor

The intent of the study is to attain a high selectivity rate and stable interaction between metals in any heterogeneous catalyst. Cyclohexene is extremely valuable in industrial domains such as the synthesis of perfumes and nylons, and the mesoporous alumina was upstretched with a various ratio of bimetal copper (10%) and nickel (5%, 10%, 15%, and 20%) under wet impregnation procedures by the mesoporous aluminum catalyst. This impregnation of a metal and catalyst was used to assess the highest conversion and selectivity of cyclohexene to cyclohexanol. This catalytic nature was validated by analyzing the crystal structure and size using the X-ray diffraction technique. The functional group is identified using FT-IR (Fourier Transform Infrared Spectroscopy), while the surface area is assessed using BET (Brunauer-Emmet-Teller). HR-TEM (transmission electron microscopy) is used to validate the morphology of catalysts and their surface layers; HR-SEM (Scanning Electron Microscopy) is used to highlight and assess microparticles; and NH3TPD (Temperature-Programmed Desorption) is used to measure the overall acidity of the catalyst. The catalytic performance was proved by the yield achieved by varying parameters such as temperature, pressure, WHSV−1, reaction time, and solvents, which yielded over 98.5% in both cyclohexene conversion and selectivity. In the conversion of the product, H2O2 performs as an oxidant, and acetonitrile serves as a solvent at constant mild conditions of 90 °C and 20 bar pressure. Furthermore, even after seven successive runs with the Al2O3/Cu (10%)-Ni (15%) mixture, remarkable reusability was attained despite a minor decline in cyclohexanol selectivity. The effective impregnation of copper and nickel into supported mesoporous Al2O3 produced a long-lasting, stable hybrid nanostructure with excellent stability and no metal leaching. The current synthesis protocol's advantages and qualities include its efficiency, cost-effectiveness, ecological sustainability, and comfort of synthesis with readily available components.

Graphene Deposited on Glass Fiber Using a Non-Thermal Plasma System

This study reports a bottom-up approach for the conversion of cyclohexane into graphene nanoflakes, which were then deposited onto fiberglass using a non-thermal generator. The composite was characterized using transmission electron microscopy, which revealed the formation of stacked few-layer graphene with a partially disordered structure and a d-spacing of 0.358 nm between the layers. X-ray diffraction confirmed the observations from the TEM images. SEM images showed the agglomeration of carbonaceous material onto the fiberglass, which experienced some delamination due to the synthesis method. Raman spectroscopy indicated that the obtained graphene exhibited a predominance of defects in its structure. Additionally, atomic force microscopy (AFM) analyses revealed the formation of graphene layers with varying levels of porosity.

Lewis Acid‐Catalyzed Ring‐Opening Alcoholysis of Cyclohexene Oxide: The Role of Open Metal Sites in the Bi(III)‐based Metal‐Organic Framework SU‐101

AbstractSU‐101 was screened for the acid‐catalyzed ring‐opening alcoholysis of cyclohexene oxide. Results indicated access to open metal sites within SU‐101, a fundamental requirement (Lewis acid Bi+3 sites) for this reaction. In addition, SU‐101 exhibited high chemical stability, demonstrated by retaining its crystalline structure after the reaction. The cyclohexene conversion was estimated to be 99.8, 96.8, and 14.3 % at 40 °C for methanol, ethanol, and propanol, respectively. Also, SU‐101 demonstrated an outstanding catalytic cyclability performance for five cycles without losing catalytic activity.