Conventional Means Research Articles

Finely controlled bioceramic granules and sonoporation for osteogenic bone defect repair and reconstruction

Osteoporotic fractures caused by imbalance in bone homeostasis like chemotherapy, loss of ovarian function，glucocorticoid use and aging require special surgical procedure to treat and restore anatomical function. However, due to escalating bone weakness and impairment, it remains a clinical challenge to treat these types of fracture defects through conventional means. Herein, we fabricated a novel calcium silicate‑strontium (CS-Sr35) bioceramic granules with high biological properties and combined it with ultrasound aided sonoporation (sono) in augmenting osteoporotic critical-sized bone defect. The use of sonoporation mediated by microbubble was to influence efficient response for tissue permeability and delivery of bioactive ions from the bioceramic scaffold. The graded robust granule with adjustable microstructure exhibited physiochemical and biointegration properties favorable for ion release in vitro and osteogenic related activities in vivo. Herein, we compared the treatment of bone defect repair using (i) no scaffold (ii) CS-Sr35 only and (iii) CS-Sr35 + sono. The gradual bone repair process was elucidated by X-ray, histology and micro-CT analyses. Overall, our results showed that the CS-Sr35 + sono exhibited a tailored biodissolution behavior with complete defect repair and reconstruction. Meanwhile, the group with only CS-Sr35 granules had less osteoblastic healing while the blank group showed inadequate critical-sized defect repair throughout the study. Our study suggests that, the synergistic technique of combining bioceramic granule with sonoporation significantly optimizes osteogenic activity and biomineralization ability of the bioceramic granule for new bone growth in osteoporotic pathology and also this tailored technique provides versatile approach for improving the biological effect for next generation reconstruction and repair of diseased bone defect.

Deep learning based signal processing and detection for multiple medical devices OFDM systems

In general multiple medical devices orthogonal frequency-division multiplexing (OFDM) communication systems, all the interfering medical users are legitimate but will cause disturbance to the desired user. In this work, we evaluate three deep learning (DL) algorithms: fully connected deep neural networks, convolutional neural networks, and long short-term memory neural networks for signal processing and detection in uncoded multiple medical devices OFDM communications systems. The bit error rates (BER) of these DL methods are compared with the conventional linear minimum mean squared error (LMMSE) detector. Additionally, the relationships between the BER and signal-to-interference ratio, signal-to-noise ratio, the number of interferences, and modulation type are investigated. Numerical results show that DL methods outperform LMMSE under different multiple medical device interference situations and are robust when the wireless channel has high variability. Also, DL methods are proven to have strong anti-interference ability and are useful in multiple medical devices OFDM systems.

Improving Gaussian channel simulation using nonunity-gain heralded quantum teleportation

Gaussian channel simulation is an essential paradigm in understanding the evolution of bosonic quantum states. It allows us to investigate how such states are influenced by the environment and how they transmit quantum information. This makes it an essential tool for understanding the properties of Gaussian quantum communication. Quantum teleportation provides an avenue to effectively simulate Gaussian channels, such as amplifier channels, loss channels, and classically additive noise channels. However, implementations of these channels, particularly quantum amplifier channels and channels capable of performing Gaussian noise suppression, are limited by experimental imperfections and nonideal entanglement resources. In this work, we overcome these difficulties using a heralded quantum teleportation scheme that is empowered by a measurement-based noiseless linear amplifier. The noiseless linear amplification enables us to simulate a range of Gaussian channels that were previously inaccessible. In particular, we demonstrate the simulation of nonphysical Gaussian channels otherwise inaccessible using conventional means. We report Gaussian noise suppression, effectively converting an imperfect quantum channel into a near-identity channel. The performance of Gaussian noise suppression is quantified by calculating the transmitted entanglement. Published by the American Physical Society 2024

Exploring De-Pragmatization as a Language Enrichment Strategy with Reference to Iraqi Arabic

This study deals with having the pragmatic force of a given expression be lost under certain processes of de-contextualization, conventionalization and abstraction. This phenomenon is introduced under the term ‘de- pragmatization’. It is addressed as a broad strategy that enriches language with new contexts of use for expressions that already exist in different contexts. The phenomenon in question is tested via selected expressions from Iraqi Arabic, as an objective to explore the strategies of de-pragmatization to borrow new contexts through certain strategies such as semantic erosion, formalization, institutionalization, disambiguation, simplification, elimination of the cultural aspects, loss of context, literalization, avoiding pragmatic markers, and abstractions. The de-pragmatized expressions can be identified with such features as recontextualization, minimizing illocutionary load, conventional meaning, frequent use, and used by people of influence. This process plays a key role in shaping language and future communication modes as it can be viewed as a significant indicator of a language’s adaptability and responsiveness to societal paradigm shifts.

COVID-19 as a driver for e-participation: insights from participatory budgeting in Poland

PurposeThis paper explores how COVID-19 has impacted the shift from public participation by conventional means to e-participation. Specifically, we investigated to what extent COVID-19 has been a driver for electronic participation in community participatory budgeting, which is a kind of residents’ consultation on how to spend part of a budget on local projects. We expounded on the concept of e-participation and its sub-concepts and investigated how these were applicable to participatory budgeting.Design/methodology/approachWe interviewed 34 leading managers in five City Halls in Poland regarding their views and experiences with moving public interactions related to participatory budgeting online during COVID-19.FindingsThe findings indicated that COVID-19 has accelerated the digitalization of the participatory budgeting processes and, to some extent, may have increased community participation in general. We observed increased e-participation in the forms of e-consultation, e-deliberation, e-lobbying and e-voting.Originality/valueMainly, this study contributed to the field by providing empirical evidence that COVID-19 increased various forms of e-participation as related to participatory budgeting. Moreover, we delineated various forms of e-participation and mapped them to activities in participatory budgeting.

A means of destroying sites of perennial root shoot weeds with pests and diseases in them

BACKGROUND: The subject of the study is the technological process of protective spraying of agricultural crops using a combined method against perennial weeds in sites in the field using two pneumohydraulic devices with slot atomizers as part of an improved small-sized boom sprayer. AIM: Development of a technical mean for exterminating sites of perennial root shoot weeds with pests and diseases in them. METHODS: The developed pneumohydraulic devices were used for an improved mounted boom sprayer of plants to treat sites of perennial weeds in the field. Chemical spraying with combined use of the traditional method and the developed pneumohydraulic devices with axial fans and 12 V electric motors, ensuring the distribution of droplet liquid on the treatment surface with two sprayers over 4 meters, is able to reduce the amount of the applied chemicals compared to the conventional technology and to reduce the pesticide load on crop plants by local destruction of sites of weeds, pests and diseases. Based on the developed methods, the results of spraying the surface with a drop liquid with a known dispersion using slot sprayers and controlled liquid pressures with a dial gauge during experiments were obtained. SCIENTIFIC NOVELTY: For the first time, a combined method and technical mean of achieving the research aim have been proposed for the destruction of sites of perennial weeds in the field and the diseases and pests of agricultural crops spread in them. RESULTS: When using a mounted sprayer with two containers for working fluids of combined herbicide solutions or for an insecticide solution in one of the containers and installation of the improved pneumohydraulic devices on the edges of the boom with a conventional arrangement of slot atomizers, it is possible to meet agrotechnical requirements for the use of herbicides, insecticides and fungicides. The simultaneous impact of large drops of herbicides on weeds and the penetration of small drops into plants will destroy sites of rhizome and root weeds with pests and diseases to ensure favorable conditions for the production of agricultural crops. CONCLUSION: A combined method and the technical mean of chemical treatment of perennial weeds with pests and diseases to create favorable conditions for the production of cultivated plants has been experimentally substantiated. Compliance with the conditions is ensured by equipping the mounted sprayer with two containers, pumps for supplying liquid through hoses to slot atomizers, and installing pneumohydraulic liquid nozzles at the edges of the boom. Working liquid sprayers ensure spraying width of more than 4 m, taking into account the size of a site, as well as spraying inaccessible areas using conventional technical means. The efficiency of the developed combined protective spraying of agricultural crops against perennial weeds and pests by the technical mean of its implementation lies in the savings of expensive herbicides and insecticides up to 70% in the later stages of their growing season (as they grow over the field area) compared to the forced continuous application of the herbicide over the entire field area.

Zanlock Bricks: One-Size-Fits-All Solution to Interlocking Bricks Shape and Form for Wall Construction in Nigeria

This project underscores the interest that the use of interlocking bricks, called mortarless construction, has generated in the last couple of decades in Nigeria in replacement of conventional means of wall construction. Although the focus of all interlocking bricks seems to be on elimination of mortar as a component of wall construction and hence reduction of cost and labour, as well as enhancement of speed of construction, the vastness of the number of shapes and forms in which interlocking bricks seem to be emerging, appears to give the impression of an anxiety to show which of the emerging forms has the most innovative design. Having observed the prospective value and sustainability of the mortarless construction idea, this study has sought to make its own foray into the field by taking the idea a notch higher. From the review of the plethora of forms and shapes of the existing interlocking systems, the study has developed a more unique interlocking brick system named Zanlock Bricks, designed to be a “one-sizefits-all” solution to the cornucopia of the available interlocking brick shapes. It creates a form whose interlocking combinations appear endless and depend only on the creative ingenuity of the builder. Taking advantage of these apparently endless combinations of the Zanlock Bricks, the study has further introduced a new concept called Design for Deconstruction (DfD) which permits disassembly and reconstruction of forms of the mortarless construction as many times as circumstances may demand and in as many different configurations and in as many locations as the ingenuity of the builder permits his creative exploration, in order to allow for flexibility of the houses that may be needed for the poor and the most vulnerable groups in Nigeria.

Awareness and acceptability of assisted reproductive technology among non-medical tertiary students in a low-resource setting

BackgroundAssisted Reproductive Techniques (ART) have significantly advanced infertility treatment worldwide. However their availability and use in sub-Saharan Africa, remains limited although infertility is highly prevalent, with significant psycho-social challenges including stigma. This study assessed the awareness, attitudes, and perceptions of ART among non-medical tertiary students in Ghana.MethodA cross-sectional study was conducted among non-medical students in tertiary institutions in Ghana. Pre-tested questionnaires were administered to both post-graduate and undergraduate students after obtaining informed consent. Ethical approval was obtained from the Review Board at Community Health Department of the University of Ghana Medical School. The data collected was analyzed using SPSS (version-27) and the results presented using frequency tables, graphs, and charts. significance was P-value below 0.05 was considered statistically significant.ResultsOverall, 196 participants from the two largest universities and other tertiary institutions in Ghana took part in this study. Majority (63.5%) of respondents demonstrated awareness on ART services, but 60.3% showed poor knowledge of the types of ART. Males generally exhibited lower knowledge of ART services compared to females, and knowledge of ART services showed an inverse relationship with age. In-vitro fertilization (IVF) was the most widely recognized and recommended ART technique, known by 65.1% of respondents who were aware of the types of ART. Most participants expressed reluctance to accept or recommend gamete donation due to religious reasons, fear of complications, and a preference for conventional means of procreation.ConclusionThe majority of tertiary students in Ghana are aware of ART for infertility treatment however, many are hesitant toward donor-gamete treatment protocols. Fear of complications and related costs pose major barriers to considering ART among the respondents. Participants unanimously suggested government subsidies and the inclusion of ART under the national health insurance coverage package.

Tunable Ambipolar Transport in a 2D Kagome Semiconductor

AbstractThe interference of electronic wavefunctions within a Kagome lattice can result in a flat band structure, where low‐energy electrons exhibit highly correlated behavior, facilitating exploration of interactions among intriguing electronic states. However, the inherent high carrier density in most known Kagome materials often hampers the manipulation of these quantum phenomena through conventional means, such as gate voltage. In this work, a unique tunability in the electrical and optoelectronic properties of exfoliated Nb3I8, a 2D semiconductor featuring a “breathing” Kagome lattice is uncovered. Characterization via temperature‐dependent ARPES confirms its semiconducting nature with a flat band structure. Experimental results from bias and gate voltage dependent transport measurements on thin film Nb3I8 transistor devices demonstrate ambipolar conductance. Notably, these findings reveal a broadband photoresponse in the device, spanning from visible to near infrared wavelengths (532 −1100 nm), with the photocurrent showing gate‐dependent characteristics that mirror the dark current's ambipolar nature. This observation marks the first instance of ambipolar transport in a Kagome semiconductor, opening up exciting new avenues for electronic and optoelectronic device development.

The benefits and potential of pre-emptive weed biological control: Three case studies in Queensland, Australia

Invasive weed species can have significant impacts on agriculture, biodiversity and livelihoods. The cost and feasibility of managing these species using conventional means can be prohibitive depending on the size of the infestations or the habitats in which they invade. Under these conditions, biological control is seen as a viable, sustainable means to manage many weeds. However, biological control can take many years and at considerable cost to achieve the desired level of control, due to the numerous steps that are involved, including native range surveys and host-specificity testing of potential agents. Pre-emptive biological control targeting particularly high-risk species prior to their arrival in a country or emerging weeds can be cost-effective, especially if the respective biological control agents have been utilized in other countries. While pre-emptive biological control of arthropods has been investigated previously, there are few examples of pre-emptive biological control of weed species. The invasive weed species, Chromolaena odorata, Mikania micrantha and Coccinia grandis have all been or are currently targets of pre-emptive biological control in Australia. Research on the gall fly Cecidochares connexa was initiated prior to its host, C. odorata being detected in Australia. Cecidochares connexa was eventually released in Australia to control C. odorata, after initial research on the agent found it to be suitably host specific and effective against the target weed. Cecidochares connexa has also been released in numerous other countries in Africa, Asia and the Pacific, where it is providing very good control. Australia funded research on the rust Puccinia spegazzinii as part of a project involving Fiji and Papua New Guinea while the target weed, M. micrantha was a target for eradication in Queensland. The rust was later approved for release in Australia to control M. micrantha following additional host-specificity testing. However, research funded by Australia overseas suggests that the rust may not be able to suppress M. micrantha populations below current levels. Consequently, while P. spegazzinii has been released in numerous countries now, it has not yet been field released in Australia. Biological control research in Australia on C. grandis is relatively new as the weed is relatively minor and not yet declared a target for biological control. Consequently, no biological control agents have yet been released in the country. Pre-emptive biological control of C. odorata and M. micrantha has been particularly cost-effective, not just for Australia, but subsequently for numerous other countries where these weeds were well-established and problematic and the respective biological control agents were later released.

Live magnetic observation of parahydrogen hyperpolarization dynamics

Hyperpolarized nuclear spins in molecules exhibit high magnetization that is unachievable by classical polarization techniques, making them widely used as sensors in physics, chemistry, and medicine. The state of a hyperpolarized material, however, is typically only studied indirectly and with partial destruction of magnetization, due to the nature of conventional detection by resonant-pickup NMR spectroscopy or imaging. Here, we establish atomic magnetometers with sub-pT sensitivity as an alternative modality to detect in real time the complex dynamics of hyperpolarized materials without disturbing or interrupting the magnetogenesis process. As an example of dynamics that are impossible to detect in real time by conventional means, we examine parahydrogen-induced 1H and 13C magnetization during adiabatic eigenbasis transformations at [Formula: see text]T-field avoided crossings. Continuous but nondestructive magnetometry reveals previously unseen spin dynamics, fidelity limits, and magnetization backaction effects. As a second example, we apply magnetometry to observe the chemical-exchange-driven 13C hyperpolarization of [1-13C]-pyruvate-the most important spin tracer for clinical metabolic imaging. The approach can be readily combined with other high-sensitivity magnetometers and is applicable to a broader range of general observation scenarios involving production, transport, and systems interaction of hyperpolarized compounds.

The incremental value of Histogram Analysis in the differentiation between hyperdense cysts and solid renal masses on unenhanced CT images.

To investigate the utility of voxel histogram analysis (HA) for differentiating hyperdense renal cysts from small solid masses on unenhanced computed tomography (CT) scans. A retrospective analysis of 99 hyperdense cystic lesions and 28 solid malignant lesions was conducted using a radiological database (from 2015 to 2021) and a pathological database (from 2010 to 2020). The study investigated the distribution of voxel attenuation values using percentiles to establish reliable criteria for differentiation after drawing a region of interest (ROI) in the centre of the lesions. The standard of reference was a histopathological diagnosis for malignant masses and contrast-enhanced CT or magnetic resonance imaging (MRI) for cysts. HA provided higher diagnostic accuracy than the conventional mean attenuation value of 70 Hounsfield Units (HU). For the 75th and 90th percentiles ± 1 standard deviation, accuracies of 77.2% (95% confidence interval 68.9-84.2%) for the 75th and 68.5% (59.7-76.4%) for the 90th were found, versus 37.0% (28.6-46.0%) for the 70 HU threshold criterion. A Gaussian distribution of voxel attenuation values was observed in 88.9% of the lesions, suggesting that it is feasible to calculate these parameters from a single measurement. The study underscores the potential of HA as a valuable tool for characterizing hyperdense cysts on unenhanced CT by using the same ROI for measuring lesion attenuation. HA could offer additional value beyond the 70 HU criterion and possibly influence clinical decisions. Multi-institutional studies are necessary for external validation to confirm its generalizability and more extensive applicability.

Innovative simplified approach and numerical investigation for flow and heat transfer in internally threaded tubes

Internally threaded tubes exhibit exceptional heat transfer capabilities, holding paramount significance in enhancing energy efficiency, reducing energy consumption, and tackling thermal challenges across aerospace, automotive, and environmental domains. Nonetheless, their intricate structural features, software modelling intricacies, extensive grid requirements, and challenges in maintaining grid quality render numerical simulation investigations a demanding endeavor. This study elucidates the influence mechanisms of thread spacing on the distribution of single-phase and two-phase flows. It delves into the condensation heat transfer of the R32 refrigerant and the single-phase heat transfer of water within internally threaded tubes. At the same Reynolds number, the heat transfer rate can be improved by approximately 19.61% with the optimized internally threaded parameters. When the Reynolds number varies from 18,626 to 51,222, the heat transfer rate per unit length for Tube-5 remains around 2,478.9 W/m, with a variation of less than 5.19%. Furthermore, it presents a simplified numerical simulation approach tailored for internally threaded pipes. This method manipulates wall roughness and regulates wall rotation speed to mimic fluid dynamics phenomena akin to conventional numerical simulation techniques. The findings reveal that the proposed simplified numerical simulation approach yields heat transfer and pressure drop predictions with less than 3% discrepancies compared to traditional numerical simulation predictions. Simultaneously, compared to directly simulating threaded pipes through conventional means, this approach significantly mitigates grid generation complexities, slashing computational time costs by at least 85% and facilitating efficient thermal design and structural optimization processes.

Design and structural optimization of an assembled re-entrant auxetic structure

Abstract Auxetics represent a class of metamaterials that possess the unique quality of exhibiting a negative Poisson ratio. Considering the fact that the cross-section is reduced during compressive loadings, this class of materials and structures exhibit superior energy absorption capabilities in impact loadings, as the density of the material increases near the contact region. In this study, a novel approach in obtaining re-entrant auxetic structures is presented, consisting of the assembly and joining of components with simple geometries, that can be manufactured through conventional means (as opposed to additive manufacturing). The dimensions and aspect ratios of the structural members was evaluated numerically in order to obtain the optimal stiffness and strength values for a given mass. The design aspect also included special features that allows the assembly through shape, which facilitates the subsequent joining operation (welding or brazing).

Examining traditional methods of handling domestic violence in a Southeastern Nigerian state: the imperative for social workers’ involvement

ABSTRACT This study investigates the conventional methods used to combat domestic violence within cultural contexts in a local council in Nigeria’s Southeastern state. The study aims first to promote the use of traditional methods of resolving domestic violence that aim at ensuring family unity and second, the need for social workers’ engagement in conventional means of resolving domestic violence. A qualitative study methodology was employed, using in-depth interviews to elicit data from twelve adult Nigerians residing in a local council of a southeastern state. Thematic analysis was adopted to analyze the data. The study discovered significant factors, including poverty, anger, and patriarchal structures, as predictors of domestic violence with substantial repercussions on family cohesion and the mental health of those affected. The findings revealed that people in the study area are well-versed in traditional methods for handling domestic violence, with family elders and traditional and religious leaders playing a crucial role. The study reveals that people are unaware of social work professionals’ involvement in domestic violence management, mainly due to the relatively new and emerging nature of formal social work practice. We suggest the inclusion of social workers for effective and efficient use of traditional approaches in handling domestic violence. Their engagement becomes essential in propagating awareness about better system trust to encourage the use of conventional methods to ensure family protection, preservation, and reunification, unlike the formal legal system. The study, however, indicated that effective collaboration among social workers, policymakers, and community stakeholders is essential to develop comprehensive policies that effectively tackle the issue of domestic violence. Overall, the study recommends a collaborative effort by social workers and community stakeholders to develop strategies and identify adequate linkages to prevent possible social injustice resulting from patriarchal norms within the cultural context that may affect their intervention.

A new adaptive approach for bridging the gap in insurance premium estimation

This paper proposes a new adaptive approach called adaptive mean (ADM) that combines the strengths of trimming and winsorization to minimize the mean square error (MSE). ADM will contribute significantly to insurers by enabling them to mitigate risk exposure caused by inaccurate premium estimation and establish more precise premiums for their clients. Furthermore, the proposed mean offers several pros compared to the conventional mean. It facilitates the natural and intuitive calculation of risk loading, identifies and measures the impact of large claims, and analyzes premium susceptibility to skewed risk by capturing the tails of the relevant loss models. In addition, this paper reviews two established, robust credibility methods (trimming and winsorization). It compares them with our proposed method, resulting in a more reliable and robustly accurate method for credibility premium estimation. We presented and analyzed two real data sets from engineering insurance companies and the Wisconsin Office of the Insurance Commissioner to highlight the advances of ADM in minimizing the MSE and building more robust credibility models that are less vulnerable to outlier events and model uncertainty.

De la bruja “pecadora” a la bruja “demente”

The case of what happened with witchcraft and sorcery between the 14th and 18th centuries is paradigmatic when it comes to understanding the evolution of the consideration of crime as a mental illness between the 19th and 20th centuries. Witchcraft went from being considered as an exceptional crime very difficult to prove by conventional means, requiring a special procedure for its clarification, to becoming a medical problem centered in the search for diabolical stigmata, and even encouraged by possible situations of drugs consumption. From there to the falsely humanitarian consideration of witches as crazy persons, with the great sociopolitical and religious advantages that derived from this, there was only one step. The logical consequence of this perspective was the consideration of crime and social exclusion as public health problems and, therefore, transform them in matters of medical, psychiatric and hygienic issues. A history that should not be lost sight at present times. The new accusatory and stigmatizing public policies in relation to the treatment of those who do not fit into the general social picture can, as well, be considered like a new chapter of this issue of deep historical significance.

Global regulatory policies for animal biotechnology: overview, opportunities and challenges.

Genome editing (GnEd) has the potential to provide many benefits to animal agriculture, offering a means for achieving rapid growth, disease resistance, and novel phenotypes. The technology has the potential to be useful for rapidly incorporating traits into existing selectively bred animals without the need for crossbreeding and backcrossing. Yet only four products from animals created via biotechnology, all growth-enhanced fishes, have reached commercialization and only on a limited scale. The past failure of genetically engineered (or GM) products to reach conventional producers can largely be attributed to the high cost of meeting GMO regulatory requirements. We review the history of GMO regulations internationally, noting the influence of Codex Alimentarius on the development of many existing regulatory frameworks. We highlight new regulatory approaches for GnEd organisms, first developed by Argentina, and the adoption of similar approaches by other countries. Such new regulatory approaches allow GnEd organisms that could have been developed by conventional means to be regulated under the same rules as conventional organisms and in the future is likely to enhance the opportunity for biotech animals to enter production. Treating certain GnEd products as conventional has had a large impact on the variety of biotechnological innovations successfully navigating regulatory processes. We suggest that for the full potential of GnEd technologies to be realized, enabling public policies are needed to facilitate use of GnEd as a breeding tool to incorporate new traits within existing animal breeding programs, rather than only a tool to create distinct new products.

War shock and the economy

AbstractThe main features of war shock are substantially different from those of the preceding COVID-19 shock. The EU economy is showing important elements of resilience. The existing structural forces and adaptive capacity of the EU economy are clear indications that it is capable of transformation and avoiding recession.The dynamics of the war is also crucial in terms of economic impacts. There are still many uncertainties about the future course of the war and its ramifications. The fundamental question is whether the war is heading in the direction of escalation or de-escalation. Unless the war spreads beyond Ukraine and the conventional means of warfare, its global economic consequences may be limited after the initial shock. New adjustment processes in the field of green and digital transition can be set in motion in parallel with the suffering and turmoil of war shock. New market players could emerge in the energy markets.The prolonged war continues to challenge the Ukrainian economy, but it can remain viable with massive external support. The Russian economy could suffer serious erosion, with its comparative advantage being wasted.There is a real threat of deglobalisation and the emergence of a fragmented world economy, but the counteracting factors appear to be much stronger. However, the prolonged war continues to pose major and unpredictable threats to the countries affected directly and indirectly, to Europe and to the world economy.

Beyond Academia: A case for reviews of gray literature for science-policy processes and applied research

Gray literature is increasingly considered to complement evidence and knowledge from peer-reviewed literature for science-policy processes and applied research. On the one hand, science-policy assessments need to consider a diversity of worldviews, knowledge types and values from a variety of sectors and actor groups, and synthesize policy-relevant findings that are salient, legitimate and credible. On the other hand, practitioners and scholars conducting applied research are affected by the time lag and biases of academic publication processes. Gray literature holds diverse perspectives informative for science-policy processes as well as practical evidence unfiltered by commercial publication processes. However, its heterogeneity has made it challenging to access through conventional means for a literature review. This paper details one endeavor within the Values Assessment of the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) to review gray literature using Google’s Programmable Search Engine. In the absence of a standardized approach, we build on the limited experiential knowledge base for reviewing gray literature and report on the potential applicability of our strategy for future reviews. Gray literature review results contrast findings of our parallel review of academic literature, underlining the importance of mobilizing different knowledge bases in science-policy assessments, evidence-based practices, and applied research.