This work focuses on the dynamic analysis of road bridges under large microsimulated traffic flows, contributing an efficient dynamic analysis framework for future fatigue, comfort or driving safety studies in which realistic interactions between vehicles are considered. Different strategies to define the loading vector in the governing dynamic equations are presented for bridges discretized with beam and shell elements. The proposed interpolation techniques for beam-like models include a recursive binary search and a novel vectorized strategy based on shape functions expanded to the entire length of the deck. These are applied to a short simply supported bridge and a very long cable-stayed bridge under traffic flows generated with a cellular automata microsimulation model. The strategies presented here reduce the computational time required in conventional load interpolation algorithms, particularly in long bridges subject to dense traffic flows. Finally, the binary search algorithm is applied to the study of bridge decks discretized with shell elements under microsimulated traffic, demonstrating that high vehicle densities increase the contribution of the transverse vibration of the slab and the potential discomfort of pedestrians.