At present, most sewage treatment plants in China generally have low sewage treatment automation and low operating efficiency. In order to solve this problem, this article takes a sewage treatment plant in Hangzhou as an example to analyze the functions and control requirements of each process in detail. Adopting three-level sewage treatment process and multiple disinfection technology at the same time, a set of sewage treatment field bus automatic monitoring system for SBR comprehensive process is designed, and the overall structure of the control system, control system hardware, control program and host computer monitoring system are given. The system adopts siemens S7-300 as the main control station, and uses industrial ethernet to complete the data exchange between the bus control and the control station on the network configuration. With various testing equipment, the inverter and MCC serve as the slave stations form a profibus control network, and complete functions such as automatic control of sewage treatment equipment and dynamic process monitoring through Wincc7.4 and Step7 V5.5. At the same time, automatic online monitoring and sampling are adopted, and video monitoring replaces manual inspection. Practice shows that the system The operation is in good condition, the effluent indicators, reliability, safety, etc. have reached the design requirements, and good economic and social benefits have been achieved. It is an integrated control system with strong practicability and high degree of automation, which is useful for further improving the automation of sewage treatment. The degree has important reference value. At the same time, the technical achievements of automatic sewage control and comprehensive treatment can fully support the sewage treatment needs during the new coronavirus epidemic, and have a wide range of application prospects.