Objective. To determine a list of psychological characteristics associated with the prognosis of prostate cancer outcome and rehabilitation potential in patients with cancer. Materials and methods. The study of psychological characteristics (subjective and personal characteristics of study participants (n = 148)) associated with rehabilitation potential was carried out using the following psychological methods: Methodology of Subjective Control Level (E.F. Bazhin, E.A. Golynkina, L.M. Etkind), Questionnaire of ways to cope (adapted by T.L. Kryukova, E.V. Kuftyak, M.S. Zamyshlyaeva), Questionnaire SF-36 “Assessment of the quality of life”, Test of vitality (adapted by D.A. Leontiev, E.I. Rasskazova), Basic Beliefs Scale (adapted by M.A. Padun, A.V. Kotelnikova). Results. A favorable prognosis for the outcome of prostate cancer is associated with the patient`s involvement in the events of his life and active participation in them, understanding of the significance of the problem, partial independence from others, slight limitation of role functioning due to the emotional state, optimal social functioning in combination with beliefs about the benevolence of the world around him and ability to control events. Conclusions. A list of psychological characteristics associated with the course of the disease in patients with prostate cancer was obtained. These psychological characteristics can define the rehabilitation potential, being associated with the possibilities of recovery after antitumor treatment.