Continuous Wound Research Articles

A Virtual Solar Wind Monitor at Mars With Uncertainty Quantification Using Gaussian Processes

AbstractSingle spacecraft missions do not measure the pristine solar wind continuously because of the spacecrafts' orbital trajectory. The infrequent spatiotemporal cadence of measurement fundamentally limits conclusions about solar wind‐magnetosphere coupling throughout the solar system. At Mars, such single spacecraft missions result in limitations for assessing the solar wind's role in causing lower altitude observations, such as auroral dynamics or atmospheric loss. In this work, we detail the development of a virtual solar wind monitor from the Mars Atmosphere and Volatile Evolution (MAVEN) mission; a single spacecraft. This virtual solar wind monitor provides a continuous estimate of the solar wind upstream from Mars with uncertainties. We specifically employ Gaussian process regression to estimate the upstream solar wind and uncertainty estimations that scale with the data sparsity of our real observations. This proxy enables continuous solar wind estimation at Mars with representative uncertainties for the majority of the time since late 2014. We conclude by discussing suggested uses of this virtual solar wind monitor for statistical studies of the Mars space environment and heliosphere.

Machine Learning Method for Forecasting Wind Power Using Continuous Wind Speed Data

Among various nonconventional energy sources, wind energy is a noteworthy and suitable source with the ability to generate electricity continuously and sustainably. However, there are a number of drawbacks to wind energy, including high basic utilization costs, the static nature of wind farms, and the challenge of locating energy that is wind-efficient. regions. Using five machine learning methods, long-term wind power prediction was done in this study using daily wind speed data. We suggested an effective way to forecast wind power values using machine learning techniques. To demonstrate how machine learning algorithms, perform, we carried out a number of case studies. The outcomes demonstrated that long-term wind power values might be predicted using machine learning algorithms in relation to past wind speed data. Additionally, the consequences show that machine learning-based Models could be used in places other than those where they were taught. This study showed that, by employing a model of a base site, machine learning algorithms could be applied frequently prior to the development of wind plants in an undisclosed environmental region, provided that it makes sense.

Charge generation by passive plant leaf motion at low wind speeds: design and collective behavior of plant-hybrid energy harvesters

Energy harvesting techniques can exploit even subtle passive motion like that of plant leaves in wind as a consequence of contact electrification of the leaf surface. The effect is strongly enhanced by artificial materials installed as ‘artificial leaves’ on the natural leaves creating a recurring mechanical contact and separation. However, this requires a controlled mechanical interaction between the biological and the artificial component during the complex wind motion. Here, we build and test four artificial leaf designs with varying flexibility and degrees of freedom across the blade operating on Nerium oleander plants. We evaluate the apparent contact area (up to 10 cm2 per leaf), the leaves’ motion, together with the generated voltage, current and charge in low wind speeds of up to 3.3 m s−1 and less. Single artificial leaves produced over 75 V and 1 µA current peaks. Softer artificial leaves increase the contact area accessible for energy conversion, but a balance between softer and stiffer elements in the artificial blade is optimal to increase the frequency of contact-separation motion (here up to 10 Hz) for energy conversion also below 3.3 m s−1. Moreover, we tested how multiple leaves operating collectively during continuous wind energy harvesting over several days achieve a root mean square power of ∼6 µW and are capable to transfer ∼80 µC every 30–40 min to power a wireless temperature and humidity sensor autonomously and recurrently. The results experimentally reveal design strategies for energy harvesters providing autonomous micro power sources in plant ecosystems for example for sensing in precision agriculture and remote environmental monitoring.

Continuous negative-pressure wound therapy improves the survival rate of skin grafts and shortens the time required for skin graft survival.

The effectiveness of negative-pressure wound therapy (NPWT) in skin graft fixation has been demonstrated in several clinical studies. However, in vitro and in vivo studies on skin graft fixation with NPWT have been scarce. In this in vivo study, we aimed to determine whether NPWT fixation enhances skin graft survival and how it contributes to improving skin graft survival biologically. We harvested skin from the bilateral abdominal wall of 88 mice after anesthetizing them. Full-thickness skin grafts (FTSGs) were performed on contralateral harvest sites, and grafts were fixed using NPWT (continuous and intermittent modes), conventional compression methods, and wrapping with polyurethane foam as a control group. On days 5 and 10 of grafting, the survival rates of the FTSGs were evaluated. Immunohistopathological analysis and measurement of the expression levels of vascular endothelial growth factor (VEGF), basic fibroblast growth factor (FGF-2), and epidermal growth factor (EGF) were performed. The survival rates of FTSG in the continuous NPWT group were significantly higher than those in the other groups. The number of capillaries in the dermis was significantly higher in the continuous NPWT group than in the other groups. In the wound bed, VEGF levels were significantly higher in both NPWT groups than in the other groups. Continuous NPWT increases the survival rate of FTSGs and shortens the duration of skin graft survival.

Single-instant spatial wave height forecast using machine learning: An image-to-image translation approach based on generative adversarial networks

An innovative single-instant approach for spatial significant wave height forecast based on a Generative Adversarial Networks (GANs) model is presented. The model's most distinctive feature is its ability to provide spatial wave height forecast with only a single snapshot of wind field input, eliminating the need for continuous wind field sequences while simultaneously maintaining high accuracy and enhanced efficiency. The proposed model architecture comprises an image-to-image translation generator and a patch-style discriminator, working in tandem to forecast high-quality wave height data. The model is trained using a 20-year ECMWF Reanalysis v5 (ERA5) wind and wave dataset. A vast sea area covering 15°-40°N, 105°-130°E in West Pacific is used for this study. The presented model is carefully tested against a 10-year period historical dataset and the results are discussed. The model exhibits outstanding overall performances with Mean Absolute Error (MAE) of 0.16 m, Root Mean Square Error (RMSE) of 0.24 m, and Mean Absolute Percentage Error (MAPE) of 13.4 %. The model proves particularly effective in forecasting extreme wave heights during tropical cyclones, capturing the structure of typhoon-driven waves and providing wave heights with favorable accuracy. It is also proficient at delivering satisfactory statistical wave height forecasts for long-term periods.

A calculation method of winding loss of high frequency transformer based on finite element method

In this paper, a winding loss calculation method used in the field of converter transformers is introduced into the realm of high-frequency transformers for the first time. In addition, the impact of winding structure on the calculation accuracy of the method is considered for the first time. Comparing the calculation results of this method with those of the formula method, based on the results of finite element simulation. The feasibility of using this method to calculate the winding loss of a high-frequency transformer is verified. First, the winding loss of rectangular wire commonly used in small-capacity high-frequency transformers is analyzed. Based on the finite element simulation results, the accuracy of the hybrid method is compared with the formula calculation method to demonstrate the feasibility of the hybrid method. Then, using the same method, the accuracy of the hybrid method in calculating the winding loss of the circular wire, which is also used in small-capacity high-frequency transformers, is compared with the formula method. The maximum number of continuous winding layers has been modified, and the outcomes for various layers are being computed. Finally, the cross-transposition winding structure is also calculated, demonstrating that the hybrid method is not only applicable to wires of various shapes but also compatible with different winding structures. The results show that the hybrid method has good calculation accuracy and applicability. It can provide more precise calculation results for the winding loss of high-frequency transformers with various winding shapes.

Analgesia for Donor Hepatectomy: Recent Perspectives

Background: Donor hepatectomy is a complex surgical procedure associated with significant postoperative pain, which can impact both short-term recovery and long-term outcomes. Adequate pain management plays a crucial role in ensuring the well-being of the living liver donor and optimising their overall experience. This review aims to provide a comprehensive overview of current practices and emerging strategies in analgesic management for donor hepatectomy. Methodology: To find relevant material, searches were conducted on PubMed and Google Scholar. The evaluation took into consideration review articles, clinical trials, retrospective studies, observational studies, and case-control studies. Results: The conventional approach to pain control involves a multimodal strategy combining opioids, non-steroidal anti-inflammatory drugs, and regional anaesthesia techniques. However, concerns regarding opioid-related side effects and potential complications have prompted a re-evaluation of analgesic protocols. Alternative methods such as thoracic epidural analgesia, transversus abdominis plane blocks and continuous wound infusion systems have gained attention for their potential to minimise opioid requirements and enhance recovery. Recent advancements in the field of pain management, including the utilisation of enhanced recovery, after surgery protocols, personalised analgesic regimens, and novel pharmaceutical agents, are explored in this review. Additionally, the impact of psychological factors and patient-centred care on postoperative pain experiences is discussed. Conclusion: The review concludes by emphasising the importance of tailoring analgesic strategies to individual patient needs and characteristics. It highlights the potential benefits of incorporating innovative approaches to enhance pain control, reduce opioid consumption and ultimately improve the overall outcome and satisfaction of living liver donors undergoing hepatectomy. Future directions in research and clinical practice are also suggested to further refine and optimise analgesic management in the context of donor hepatectomy.

Incidence and risk factors of postoperative delirium following hepatic resection: a retrospective national inpatient sample database study

BackgroundPostoperative delirium (POD) is a common complication after major surgery and can cause a variety of adverse effects. However, no large-scale national database was used to assess the occurrence and factors associated with postoperative delirium (POD) following hepatic resection.MethodsPatients who underwent hepatic resection from 2015 to 2019 were screened using the International Classification of Diseases (ICD) 10th edition clinical modification code from the National Inpatient Sample (NIS) Database. Peri-operative factors associated with delirium were screened and underwent statistical analysis to identify independent predictors for delirium following hepatic resection.ResultsA total of 80,070 patients underwent hepatic resection over a five-year period from 2015 to 2019. The overall occurrence of POD after hepatic resection was 1.46% (1039 cases), with a slight upward trend every year. The incidence of elective admission was 6.66% lower (88.60% vs. 81.94%) than that of patients without POD after hepatic resection and 2.34% (45.53% vs. 43.19%) higher than that of patients without POD in teaching hospitals (P < 0.001). In addition, POD patients were 6 years older (67 vs. 61 years) and comprised 9.27% (56.69% vs. 47.42%) more male patients (P < 0.001) compared to the unaffected population. In addition, the occurrence of POD was associated with longer hospitalization duration (13 vs. 5 days; P < 0.001), higher total cost ($1,481,89 vs. $683,90; P < 0.001), and higher in-hospital mortality (12.61% vs. 4.11%; P < 0.001). Multivariate logistic regression identified hepatic resection-independent risk factors for POD, including non-elective hospital admission, teaching hospital, older age, male sex, depression, fluid and electrolyte disorders, coagulopathy, other neurological disorders, psychoses, and weight loss. In addition, the POD after hepatic resection has been associated with sepsis, dementia, urinary retention, gastrointestinal complications, acute renal failure, pneumonia, continuous invasive mechanical ventilation, blood transfusion, respiratory failure, and wound dehiscence / non-healing.ConclusionAlthough the occurrence of POD after hepatic resection is relatively low, it is beneficial to investigate factors predisposing to POD to allow optimal care management and improve the outcomes of this patient population.

Assessing antibacterial efficacy of a polyhexanide hydrogel versus alginate-based wound dressing in burns.

Burn injuries pose a heightened risk of infection, which is primarily responsible for increased morbidity and mortality. Factors such as extensive skin damage and compromised immunity exacerbate this vulnerability. Pseudomonas aeruginosa and Staphylococcus aureus are frequently identified in burns, with Gram-negative Pseudomonas aeruginosa often resistant to antibacterial agents. While Flaminal, an alginate-based wound dressing (Flen Health, Belgium), aids wound healing, its antibacterial effects are limited compared with 1% silver sulfadiazine (1% SSD). In contrast, Prontosan Wound Gel X, a betaine and polyhexanide-based hydrogel (B. Braun Medical AG, Switzerland), has been shown to effectively combat various microbes and promotes wound healing. In this study, two research cohorts were retrospectively established (control group: patients receiving standard of care with the alginate-based wound dressing; intervention group: patients receiving the polyhexanide hydrogel wound dressing), comprising patients admitted to a burn centre between 2019 and 2022. Patients were eligible when continuous wound treatment with either of the two wound dressings was performed. Laser Doppler imaging (LDI) scans were conducted. Regions of interest (ROIs) were selected based on LDI scans and divided into healing time categories. Wound swabs were collected and the presence of Pseudomonas aeruginosa and Staphylococcus aureus was documented. Bacterial load was evaluated using a semiquantitative scale. Wound healing was recorded. The control group consisted of 31 patients with 93 ROIs, while the intervention group had 67 ROIs involving 29 patients. Both groups exhibited similar proportions of healing time categories (p>0.05). The polyhexanide hydrogel dressing outperformed the alginate-based dressing in antiseptic efficacy by significantly reducing the incidence of Pseudomonas aeruginosa- and Staphylococcus aureus-positive cultures in patients' wounds. Wound healing time for conservative treatment was comparable between groups. In this study, the polyhexanide hydrogel dressing minimised Pseudomonas aeruginosa and Staphylococcus aureus colonisation in burn wounds, demonstrating strong antibacterial properties, emphasising its potential to minimise infections in burn injuries.

Continuous flow local anesthetic wound infusion for post-operative analgesia following kidney transplantation.

Some patients with end stage renal disease are or will become narcotic-dependent. Chronic narcotic use is associated with increased graft loss and mortality following kidney transplantation. We aimed to compare the efficacy of continuous flow local anesthetic wound infusion pumps (CFLAP) with patient controlled analgesia pumps (PCA) in reducing inpatient narcotic consumption in patients undergoing kidney transplantation. In this single-center, retrospective analysis of patients undergoing kidney transplantation, we collected demographic and operative data, peri-operative outcomes, complications, and inpatient oral morphine milligram equivalent (OME) consumption. Four hundred and ninety-eight patients underwent kidney transplantation from 2020 to 2022. 296 (59%) historical control patients received a PCA for postoperative pain control and the next 202 (41%) patients received a CFLAP. Median age [53.5vs. 56.0 years, p=.08] and BMI [29.5vs. 28.9kg/m2, p=.17] were similar. Total OME requirement was lower in the CFLAP group [2.5vs. 34 mg, p<.001]. Wound-related complications were higher in the CFLAP group [5.9%vs. 2.7%, p=.03]. Two (.9%) patients in the CFLAP group experienced cardiac arrhythmia due to local anesthetic toxicity and required lipid infusion. Compared to PCA, CFLAP provided a 93% reduction in OME consumption with a small increase in the wound-related complication rate. The utility of local anesthetic pumps may also be applicable to patients undergoing any unilateral abdominal or pelvic incision.

Peripheral nerve blocks for analgesia following cesarean delivery A narrative review.

Spinal and epidural blocks are commonly employed for pain relief during and following cesarean section. Intrathecal morphine (ITM) has been the gold standard for the same for many years. In recent times, many peripheral nerve blocks (PNBs) have been tried for postoperative analgesia following cesarean delivery (PACD). This article has reviewed the common PNBs used for PACD. The role of PNBs along with ITM has been studied and the current best strategy for PACD has also been explored. Currently, Ilio-inguinal nerve and anterior transversus abdominis plane block in conjunction with intrathecal morphine have been found to be the most effective strategy, providing lower rest pain at 6 hours as compared to ITM alone. In patients not receiving intrathecal morphine, recommended PNBs are lateral transversus abdominis plane block, single shot local anesthetic wound infiltration, or continuous wound infiltration with catheter below rectus fascia. PNBs are recommended for PACD. They have an opioid-sparing effect and are devoid of adverse effects associated with central neuraxial blocks such as hypotension, bradycardia, and urine retention. However, caution must be observed with PNBs for possible local anesthetic toxicity due to the large volumes of drug required.

An Onshore Deployment of Advanced Dual-Doppler Radar for Wind Energy Applications

Two advanced X-band radars have been developed and deployed by Texas Tech University to provide continuous wind measurements serving project AWAKEN, including the construction of near real-time dual-Doppler synthesized wind fields covering a large 35 km x 35 km analysis domain. This deployment represents the first overland long duration utilization of the technology, which was configured to document a wide range of wind energy relevant flows spanning turbine inflow/wake flow to regional wind flows and wind plant interactions. The overland environment coupled with technology innovation has led to very high data availability yielding a growing archive of measurements documenting diverse atmospheric phenomena including numerous instances of wind plant interaction. Through the first few project months, data availability greater than 90%, 80% and 70% has been assessed at the ranges of 8 km, 16 km, and 25 km, respectively. Robust data availability coupled with fast radar scan speeds and high along beam measurement resolution position advanced Doppler radar technology to broadly contribute to diverse wind energy measurement applications covering domains sizes that far exceed existing industry standard measurement systems.

Assessing the costs and benefits of dynamically positioned floating wind turbines to enable expanded deployment

In addition to technical and economic challenges, the offshore wind industry must also contend with environmental and socio-political concerns that constrain development. Here, the viability of dynamically positioned floating offshore wind platforms that could ameliorate these constraints is analyzed. Such a design can unlock deeper, less-contentious waters that are farther from shore and reduce environmental interactions in the ocean, thus expanding and improving deployment opportunities. While prior studies on this application only focused on energy performance, the resulting cost of energy and benefits have not yet been quantified. Although prior studies found that the energy-performance of this strategy does not show promise, it is possible that a full understanding of the costs and benefits will reveal a decision space where it makes sense. To address this gap in the literature, the cost penalty of this application compared to moored turbines is estimated here. A physical engineering model is used to compute the environmental loads on a floating offshore wind turbine to estimate the expected energy needed by the station-keeping thrusters and one potential environmental benefit—eliminated mooring chains. The models were validated using marine engineering simulation software. Dynamic positioning realizes a cost penalty of at least 30 U.S. dollars/megawatt-hour while eliminating up to 900 km of mooring chains for a 1-gigawatt array. Up to 3 megawatt-hours of stored energy are needed to station-keep during continuous low winds. Furthermore, dynamic positioning is more viable for turbines of intermediate size (8–10 MW) rather than larger turbines (15 MW). The results show that aerodynamic loads on the turbine fall sharply beyond the rated wind speed, operational and design improvements may further improve the viability of this application, and the energy performance of this application continually improves with added thrusters although the cost of energy does not.

Structural Deformation and Displacement of a Disc Winding Due to Standard Switching Impulse Voltage via Finite Element Method

Switching operations in a power system network can lead to transient overvoltage in the high voltage (HV) winding of distribution transformers that causes high-stress build-up. This paper presents the relationship between electromagnetic force due to a standard switching impulse (SSI) and mechanical deformation/displacement behaviours for a disc-type transformer. The analysis was carried out based on a three-dimensional (3D) modelling of a continuous HV disc winding configuration whereby it is subjected to the switching transient voltage and force excitations through the finite element method (FEM). The electric transient solver analysed the static and dynamic aspects of the electromagnetic forces associated with the variation of forces versus time. The transient structural solver evaluated the structural behaviours of the disc winding related to the axial height and radial width of the winding under electromagnetic forces. It is found that the positively dominant axial force generated in the winding with a magnitude of 8.7 N causes the top and bottom layers of disc winding to tilt and displace. In addition, the positive average radial force of 1.4 N causes the circumference of the winding to experience hoop tension and outwardly stretch.

Shoelace and honey technique: An innovative and inexpensive method of wound healing

Wound closure and wound infection have been a great enemy to orthopaedic surgeons since the beginning of time. Many wound closure technique have been described and controversy exists as a optimal method. Healing by secondary intension used to be commonly employed technique but less popular nowadays. Most wound closure require split skin thickness grafting which increases morbidity and scarring and additional wound at donor site .gradual mechanical dermal apposition technique that is shoelace technique have gained popularity and have shown to be effective in closure of wounds .Shoelace technique for wound closure is widely used in other medico-surgical specialties, this technique is unusual in orthopedics surgery, but the simplicity of the procedure, demanded us to follow to our cases.Honey is most ancient wound dressing biomaterial .Honey is known for its anti-oxidant, anti-bacterial and anti-inflammatory properties which were used for better and faster wound healing. Both the methods combined together make it a magic formula for the wound healing.We have 21 patients presenting to VDGMC, LATUR from a period from May 2020 to December 2023, with difficult primary wound closure were included in the study. The patients underwent the surgical fracture fixation (if any), followed by application of shoelace technique and honey dressing for the patient. An infant feeding tube and skin staples were used for the technique. Patients were followed till the complete wound healing occurred. The average time required for the wound healing using this technique was 3.2 weeks. Once the skin was approximated by dermatotraction, delayed primary suturing was done and regular dressing protocol was followed.Our study showed an excellent wound healing in 20 cases with duration of wound healing less den 3 weeks, which also waived of the need for an extra procedure of skin grafting. 1wound had continuous wound discharge which needed an extra debridement procedure longer duration for closure.The successful out-come observed in these cases, and at a very low cost, allows for its consideration as indicated for situations similar to that presented in this study, especially in patients with poor economic background.

Continuous Wound Irrigation and Intraoperative Methadone Decreases Opioid Use and Shortens Length of Stay After CRS/HIPEC.

Epidural analgesia is resource and laborintense and may limit postoperative management options and delay discharge. This study compared postoperative outcomes after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) with epidural analgesia versus continuous wound infusion system (CWIS) with/without intraoperative methadone. A single-institution, retrospective chart review was performed including all patients undergoing open CRS/HIPEC from 2018 to 2021. Patient demographics, surgical characteristics, length of stay, and in-hospital analgesic use were reviewed. In-hospital opioid exposure in morphine milligram equivalents (MME) was calculated. Multivariate analysis (MVA) for mean total and daily opioid exposure was conducted. A total of 157 patients were included. Fifty-three (34%) had epidural analgesia, 96 (61%) had CWIS, and 79 (50%) received methadone. Length of stay was significantly shorter with CWIS + methadone versus epidural (7 vs. 8 days, p < 0.01). MVA showed significantly lower mean total and daily opioid exposure with CWIS+methadone versus epidural (total: 252.8 ± 17.7 MME vs. 486.8 ± 86.6 MME; odds ratio [OR] 0.72, 95% confidence interval [CI] 0.52-0.98, p = 0.04; Daily: 32.8 ± 2.0 MME vs. 51.9 ± 5.7 MME, OR 0.72, 95% CI 0.52-0.99, p ≤ 0.05). The CWIS-only group (n = 17) had a significantly lower median oral opioid exposure versus epidural (135 MME vs. 7.5 MME, p < 0.001) and longer length of stay versus CWIS + methadone (9 vs. 7 days, p = 0.04), There were no CWIS or methadone-associated complications and one epidural abscess. CWIS + methadone safely offers better pain control with less in-hospital opioid use, shorter length of stay, and decreased resource utilization compared with epidural analgesia in patients undergoing CRS-HIPEC.

An 8-model ensemble of CMIP6-derived ocean surface wave climate

We present a global wind wave climate model ensemble composed of eight spectral wave model simulations forced by 3-hourly surface wind speed and daily sea ice concentration from eight different CMIP6 GCMs. The spectral wave model uses ST6 physics parametrizations and a global three-grid structure for efficient Arctic and Antarctic wave modeling. The ensemble performance is evaluated against a reference global multi-mission satellite altimeter database and the recent ECMWF IFS Cy46r1 ERA5 wave hindcast, ERA5H. For each ensemble member three 30-year slices, one historical, and two future emission scenarios (SSP1-2.6 and SSP5-8.5) are available, and cover two distinct periods: 1985–2014 and 2071–2100. Two models extend to 140 years (1961–2100) of continuous wind wave climate simulations. The present ensemble outperforms a previous CMIP5-forced wind wave climate ensemble, showing improved performance across all ocean regions. This dataset is a valuable resource for future wind wave climate research and can find practical applications in offshore and coastal engineering projects, providing crucial insights into the uncertainties connected to wind wave climate future projections.

Retrospective observational study of efficacy and patient outcomes with spinal analgesia and continuous local wound infusion compared to thoracic epidural analgesia after open pancreaticoduodenectomy

Retrospective observational study of efficacy and patient outcomes with spinal analgesia and continuous local wound infusion compared to thoracic epidural analgesia after open pancreaticoduodenectomy

Hybrid ANFIS‐PI‐Based Robust Control of Wind Turbine Power Generation System

This paper introduces a novel hybrid controller designed for a wind turbine power generation system (WTPGS) that utilizes a permanent magnet synchronous generator (PMSG). This hybrid controller combines the adaptability of an adaptive neuro‐fuzzy inference system (ANFIS) with the simplicity of a proportional‐integral (PI) controller. The PI controllers are traditionally used for stability and noise handling. ANFIS adds adaptability, making it more suitable to cope with the variable nature of wind energy. The primary objective of this hybrid strategy is to augment the overall control performance and reliability of PMSG‐based WTPGS when encountered with continuous variable wind conditions. However, implementing the PI controller alone with the WTPGS often suffers from high overshoot and sluggish response in nonlinear systems like WTPGS. In contrast, ANFIS controllers offer superior performance to PI and other artificial intelligence controllers but are still susceptible to noise issues. In this paper, the proposed WTPGS system is designed in MATLAB/Simulink software where a hybrid controller (ANFIS‐PI) is implemented in the machine‐side converter (MSC) and grid‐side converter (GSC) of a variable speed PMSG‐based wind turbine to enhance its performance subjected to wind variations. The hybrid controller is implemented in such a way that the ANFIS controller is implemented in the outer layers while the PI controller is applied in the inner layers of both MSC and GSC. The simulation results for this hybrid controller in the MSC outperform those of the conventional PI controller. They demonstrate minimal overshooting and settling time, maintaining consistent stability even when subjected to various test signals at different intervals. Similarly, the GSC also surpasses conventional PI controllers, achieving a significant 6.4% reduction in maximum overshoot and a decrease of 4.36 seconds in settling time. This highlights its strong suitability for wind turbine applications.

Continuous Intra-Incisional Bupivacaine for Postoperative Analgesia after Hip Nailing Surgery: A Randomized Clinical Trial.

The effectiveness of continuous wound infiltration (CWI) as a postoperative pain-control technique has been shown in many surgical procedures. This study investigates the effect of CWI of local anesthetic on postoperative pain control in intertrochanteric fracture patients undergoing hip nailing surgery. In this randomized clinical trial, 48 patients who were scheduled for hip nailing surgery were randomly assigned to receive (n = 24) or not receive (n = 24) bupivacaine infusion through a catheter inside the surgical wound, postoperatively. Pain intensity (NRS), required dose of morphine, and drug-related complications within 24 hours of the intervention were assessed and compared. Pain intensity was significantly lower in the bupivacaine group both during the recovery room stay and in the ward in the first 24 hours after the procedure (P < 0.001). In the recovery room, the control group patients had a higher morphine consumption compared to the bupivacaine group (P < 0.001) and requested it earlier than the bupivacaine group (60 (45-60) vs. 360 (195-480) minutes) (P < 0.001). In the ward, all control group patients used the PCA morphine pump, while only 54% of the bupivacaine group self-administered morphine through the pump, with a significantly lower total morphine consumption (1 (0-2) vs. 10 (5-14) mg, P < 0.001). None of the patients in the bupivacaine group required additional morphine, while 37.5% of the control requested additional morphine (P=0.002). Altogether, the control group had a higher total morphine consumption compared to the bupivacaine group in the first 24 hours (10.5 (6-15.5) vs. 1 (0-2) mg, P < 0.001). CWI of bupivacaine helps better pain reduction during the early postoperative hours while it reduces opioid consumption, minimizes nausea and vomiting, and improves patient satisfaction.