This study introduces a decision support framework that integrates aircraft trajectory optimization and arrival scheduling to facilitate efficient management of descent operations for arriving aircraft within terminal maneuvering areas. The framework comprises three modules designed to tackle specific challenges in the descent process. The first module formulates and solves a trajectory optimization problem, generating a range of candidate descent trajectories for each arriving aircraft. The options for descent operations include step-down descent operation, Continuous Descent Operation (CDO), and CDO with a lateral path stretching strategy. The second module addresses the assignment of conflict-free trajectories to aircraft, determining precise arrival times at each waypoint. This is achieved by solving an aircraft arrival scheduling problem. To overcome computational complexities, a novel variable neighborhood search algorithm is proposed as the solution approach. This algorithm utilizes three neighborhood structures within an extended relaxing and solving framework, and incorporates a tabu search algorithm to enhance the efficiency of the search process in the solution space. The third module focuses on comparing the total cost incurred from flight delays and fuel consumption across the three descent operations, enabling the selection of the most suitable operation for the descent process. The decision support framework is evaluated using real air traffic data from Guangzhou Baiyun International Airport. Experimental results demonstrate that the framework effectively supports air traffic controllers by scheduling more cost-efficient descent operations for arrival aircraft.