This article examines the hereditary effect of microscopic dendritic segregation in the continuous-cast semifinished product on the structure (the presence of segregation-related striae and martensitic sections and their distribution over the cross section) of wire rod made of high-carbon steel. To improve the quality indices of wire rod, the casting technology should be stabilized by adding equipment for stopper-assisted pouring, fully protecting the stream with submersible refractory tubes, using modern mold-oscillation mechanisms (such as lever-type mechanisms), using parabolic molds that speed up crystallization of the CCS, and employing other measures. Maximum use should be made of heat treatment of the CCSs and rolled products, one of the goals here being to increase the degree of homogenization of the cast structure and rolled product and/or residues of that structure. This can often be achieved through longer heating of the CCS in walking-beam furnaces prior to the rolling operation.