Background and context: Continuous medical education (CME) is very important in improvement of knowledge in all field of pediatrics. CME in pediatric oncology could be aimed both for oncologists and pediatricians. Aim: We aimed to organize CME system in the field of pediatric oncology for oncologists and pediatricians. Strategy/Tactics: Continuous education for improvement of knowledge for all pediatric oncologists and pediatricians based on Russian CME system. This system was organized by the Ministry of Health and National Medical Chamber and based on continuous work of professional medical societies. Each society could propose their educational activities and receive accreditation (participants receiving educational credits). Specialist required receiving education in pediatric oncology participating this system, obtaining credits and getting new knowledge. Program/Policy process: The National Society of Pediatric Hematologists and Oncologists (NSPHO) organized a system of educational seminars in pediatric oncology with CME status and approved credits in different regions of the Russian Federation. NSPHO organizing one seminar per month, 12 seminars per year. Each seminar has three major components: organization (meetings with governments of regions), education (lectures and discussions) and workshops. These seminars are free of charge for all regions and organized with the help of resources of NSPHO. A special report with recommendations for improvement of pediatric cancer care prepared after each seminar and transferred to the Government and Ministry of Health. NSPHO organized also online CME courses with accreditation. To estimate the effectiveness of seminars we are doing surveys and estimation of quality of cancer treatment. Outcomes: All 86 centers and departments of pediatric hematology/oncology in Russia participating this system. All members of NSPHO (about 1200 participants) are studied within the single educational program including governmental certification and Russian CME educational meetings/seminars as well as online CME seminars. CME education in pediatric hematology/oncology and immunology for pediatricians allowed studying more than 1000 specialists during 2017. Estimation by surveys and quality control showed high effectiveness of seminars in early diagnostics and treatment. What was learned: CME platform for online and off-line education in Russia developing rapidly. Nowadays we involved all Russian regions to this work. Results showed high effectiveness of this approach.