Some problems such as nitrogen desorption and pores always occur in the weld metal during welding of high nitrogen steel. In order to study the nitrogen content and porosity of the weld metal of high nitrogen steel 1Cr22Mn16N, the steel was welded by CO2 laser welding, and the influence of the shielding gas composition and heat input on the nitrogen content and porosity of the weld metal was investigated. The experimental results indicate that the weld nitrogen content increases slightly with the increase of the nitrogen content in shielding gas under the same laser welding conditions. The nitrogen content of the weld metal decreases with the increase of the heat input when pure argon is used as the shielding gas, whereas that of the weld metal is improved with the increase of the heat input when some nitrogen is added to the shielding gas. The higher the heat input, the less the porosity in the weld metal, and the more nitrogen in the shielding gas, the less the porosity becomes.