Dermoid cyst (DC) is an uncommon developmental cystic malformation, lined by epidermislike epithelium containing dermal annexes in the cystic wall. A 76-year-old woman presented with a painless submucosal nodule in the ventral surface of the tongue, right side, measuring 1 × 1 cm, yellowish in color, with a soft consistency on palpation. A previous aspiration of the lesion revealed clear liquid contents. The patient, who has noticed the lesion in the past 15 days, reported no alcohol or smoking habits. DC, lipoma, and ranula were considered as possible clinical diagnoses. After biopsy, the microscopic examination revealed fragments of cystic capsule lined by a thin, stratified squamous epithelium. The cystic capsule was composed of dense fibrous connective tissue, and the cystic content exhibited an abundant amount of keratin. Minor salivary glands, nerve bundles, and muscular tissue completed the histopathologic diagnosis of a dermoid cyst. The patient remains under follow-up examination. Dermoid cyst (DC) is an uncommon developmental cystic malformation, lined by epidermislike epithelium containing dermal annexes in the cystic wall. A 76-year-old woman presented with a painless submucosal nodule in the ventral surface of the tongue, right side, measuring 1 × 1 cm, yellowish in color, with a soft consistency on palpation. A previous aspiration of the lesion revealed clear liquid contents. The patient, who has noticed the lesion in the past 15 days, reported no alcohol or smoking habits. DC, lipoma, and ranula were considered as possible clinical diagnoses. After biopsy, the microscopic examination revealed fragments of cystic capsule lined by a thin, stratified squamous epithelium. The cystic capsule was composed of dense fibrous connective tissue, and the cystic content exhibited an abundant amount of keratin. Minor salivary glands, nerve bundles, and muscular tissue completed the histopathologic diagnosis of a dermoid cyst. The patient remains under follow-up examination.