To achieve sustainable development, ecosystem strategy has gradually become an inevitable trend of contemporary organizations in the digital era. Thus, ecosystem strategy has been an enduring research topic in recent years. Since ecosystem strategy advocates symbiosis with partners, this strategy highlights the importance of internal and external resource of focal enterprises. However, the prior literature has largely overlooked the utilization process of resources internally and externally in ecosystem strategy from a resource orchestration perspective, this study explores how a focal enterprise implement resource orchestration in the ecosystem strategy for sustainability in the digital era. Using a Chinese case study of TY, which successfully developed its own business ecosystem, this study unveils the important role of resource orchestration in ecosystem strategy, identifies two resource orchestration mechanisms: the bricolage of external resources and the activation of internal resources respectively This study also highlights the importance of interaction between the two mechanisms for sustaining continuous resource orchestration and enabling the organization to adapt to the dynamic ecosystem environment. This study also identifies the corresponding dynamic capabilities in the process of implementing resource orchestration. The enterprise needs to build the boundary-spanning capability while using resource bricolage mechanism to obtain external resources,meanwhile,the enterprise needed to build the reconfiguration capabilities while using the resource activation mechanism to maximize the utility of internal resources. These findings contributes to the ecosystem strategy and resource orchestration theory, and also providing significant actionable paradigm to implement ecosystem strategy for sustainability.