The degradation of water supplies is linked with poor anthropogenic activities. This study determines that contamination of water supply occurs because of destabilization of pipe material and deposits in the water distribution system due to physiochemical and microbiological processes that have developed over decades and cause health issues (Hepatitis C, and GIT disorders) which result in the death rate of 3.4 million people over the globe. This study was conducted in Gujrat, Pakistan and the primary source of data collection was a survey questionnaire while secondary sources involved a comprehensive literature review. ANOVA test, Correlation, and reliability analysis were applied to test the variables. The results of this study revealed that contaminated water supplies, oxyhydroxide products of corrosion, the mixture of sewage, and industrial effluents were significantly associated with the contamination of water supplies. The findings of this study also explore the contamination of household store water (HSW), contaminated water supplies, and the mixture of sewage, and industrial effluents that were responsible for water contamination, whereas; the condition of underground water supply pipelines was very worse. The use of upgraded water supply systems and water purification technologies is a common global practice that would be useful to reduce water supply contamination. The findings of this study will contribute to the literature on water supply contamination, the framework of water quality parameters, and low-cost adaptable water treatment techniques.