Abstract BACKGROUND: Tuberculosis (TB) is a highly contagious infectious disease that is still considered one of the main causes of mortality associated with infectious diseases. To effectively prevent, treat, and diagnose TB, it is essential to analyze and interpret the funds allocated by health agencies and countries to treat, prevent, and diagnose TB. METHODS: In this study, the World Health Organization and research databases were used to analyze the financial status of TB prevention, diagnosis, and treatment over the past 20 years. RESULTS: Based on the results of this study between 2006 and 2021, Europe (22,469.488), Asia (18,708.125), and Africa (14,373.899) received the most funding (US $ million). Oceania (202.655) and America (3117.571) were allocated the lowest budgets (US $ million). The highest and lowest TB eradication budgets were in Asia and Oceania, respectively. As far as funding for drug-resistant TB is concerned, Europe and Oceania had the highest and lowest levels of funding between 2006 and 2021. CONCLUSIONS: Funding allocations for TB programs have generally been found to be the highest, potentially reducing the number of treatment-resistant TB cases and the devastating costs associated with this disease.