Contact Points Research Articles

Temporal evolution of mechanical properties in PDMS: A comparative study of elastic modulus and relaxation time for storage in air and aqueous environment

Polydimethylsiloxane (PDMS) is a soft, biocompatible polymer extensively employed in biomedical research, notable for its tunable mechanical properties achieved through cross-linking. While many studies have assessed the mechanical properties of PDMS utilizing macroscopic and microscopic methods, these analyses are often limited to freshly prepared samples. However, the mechanical properties of PDMS can be expected to change during prolonged exposure to water or air, such as interface polymer chain loosening or surface hardening, which are critical considerations in applications like cell culture platforms or microfluidic devices. This paper presents a comprehensive 10-day investigation of the evolution of PDMS surface mechanical properties through AFM-based nano-indentation. We focused on the most commonly utilized crosslinker-to-base ratios of PDMS, 1:10 (r10) and 1:20 (r20), under conditions of air and deionized water storage. For r10 samples, a hardening process was detected, peaking at 2.12 ± 0.35 MPa within five days for those stored in air and 1.71 ± 0.16 MPa by the third day for those immersed in water. During indentation, the samples displayed multiple contact points, suggesting the formation of distinct regions with varying mechanical properties. In contrast, r20 samples exhibited better stability, with an observed elastic modulus averaging 0.62 ± 0.06 MPa for air-stored and 0.74 ± 0.06 MPa for water-stored samples. Relaxation experiments, interpreted via the General Maxwell Model featuring two distinct component responses, a relatively consistent fast response τ1 (on the order of 10−1 s), and a more variable, slower response τ2 (on the order of 10 s), throughout the study period. The identification of two distinct relaxation times suggests the involvement of two disparate material property regimes in the relaxation process, implying changes in the surface material composition at the interface with air/water. These variations in mechanical properties could significantly influence the long-term functionality of PDMS in various biomedical applications.

Lost in space and time: robust demography and enhanced resilience buffer adverse environmental effects in a highly isolated and sedentary pre-pleistocene landscape vertebrate

BackgroundFew animal populations have been studied under the framework of the OCBIL theory, which addresses the ecology and evolution of biodiversity on old climatically buffered infertile landscapes. Available genetic data challenge the low connectivity and high genetic differentiation predicted for isolated tepui-summit vertebrate communities, suggesting potential dispersal among summits. However, the OCBIL theory posits reduced dispersibility, enhanced resilience to habitat fragmentation and inbreeding due to small populations. We tested these hypotheses by conducting the first analytic evaluation of the spatial ecology and population biology of a tepui-summit vertebrate at multiple spatial scales.ResultsWe used harmonic radar tracking (100 individuals/448 points of contact) and capture-mark-recapture data (596 individuals captured/52 recaptured) to reveal the temporal niche, microhabitat use, population size, and dispersal abilities of the tepui-summit endemic toad Oreophrynella quelchii on Roraima-tepui. Abundance was determined using a closed population model incorporating sources of variation in capture probability. We tested the relative influence of biotic and abiotic variables on distances moved through model selection. Our data indicate that the population size of O. quelchii is remarkably large (ca. 12 million individuals), with strong seasonal demographic fluctuations. Ecology and observed limited spatial movements challenge the likelihood of active dispersal among tepui tops in this species. Our results are counter to those predicted by the available genetic data but support two hypotheses of the OCBIL theory: reduced dispersibility and enhanced resilience. However, they do not support the expectation of a small refugial population size.ConclusionWe postulate that the insular, hostile tepui-summit environment tends to produce robust demographic populations, likely to buffer stochastic adverse environmental effects, rather than diversity, as observed in much younger post-Pleistocene Neotropical landscapes. Our results draw attention to the value of faunal studies using an OCBIL framework to better understand the ecology and evolution of this unique biota worldwide.

Debate: Bridging the gap - role of nonspecialists in child and adolescent mental health care.

The first point of contact for patients and families seeking professional help for health problems is often in nonspecialist community healthcare settings that vary widely across the countries in funding sources, resources and support from specialist services. They typically involve general practitioners, family physicians, general and community paediatricians, and nonphysician health workers such as nurses, social workers and public health professionals. This article discusses the role of nonspecialists in addressing the challenges of limited resources in Child and Adolescent Mental Health (CAMH) care services as healthcare systems struggle to meet the high demand. Stakeholders and decision-makers need to reconsider traditional healthcare models and service delivery. Integrating nonspecialist community care can be a potential solution but is beset with ethical, geopolitical, practical and economic challenges. The urgency and complexity of the issue are highlighted, emphasising the need for global discussion around CAMH care.

Ballistic Electron Source with Magnetically Controlled Valley Polarization in Bilayer Graphene.

The achievement of valley-polarized electron currents is a cornerstone for the realization of valleytronic devices. Here, we report on ballistic coherent transport experiments where two opposite quantum point contacts (QPCs) are defined by electrostatic gating in a bilayer graphene (BLG) channel. By steering the ballistic currents with an out-of-plane magnetic field we observe two current jets, a consequence of valley-dependent trigonal warping. Tuning the BLG carrier density and number of QPC modes (m) with a gate voltage we find that the two jets are present for m=1 and up to m=6, indicating the robustness of the effect. Semiclassical simulations confirm the origin of the signals by quantitatively reproducing the jet separations without fitting parameters. In addition, our model shows that the ballistic current jets have opposite valley polarization. As a consequence, by steering each jet toward the detector using a magnetic field, we achieve full control over the valley polarization of the collected currents, envisioning such devices as ballistic current sources with tunable valley polarization. We also show that collimation experiments are a sensitive probe to the trigonal warping of the Fermi surface.

Churning the tides of care: when nurse turnover makes waves in patient access to primary care

BackgroundTeam-based primary care (PC) enhances the quality of and access to health care. The Veterans Health Administration (VHA) implements team-based care through Patient Aligned Care Teams (PACTs), consisting of four core members: a primary care provider, registered nurse (RN) care manager, licensed vocational nurse, and scheduling clerk. RNs play a central role: they coordinate patient care, manage operational needs, and serve as a patient point of contact. Currently, it is not known how varying levels of RN staffing on primary care teams impact patient outcomes.ObjectiveThis study aims to empirically assess how the stability of RN staffing within team-based primary care affects patient access to care.MethodsA retrospective database review using clinical and administrative data from the VHA over 24 months. Participants included 5,897 PC PACTs across 152 VHA healthcare facilities in the United States and its territories. The stability of personnel in the RN role was categorized as: RN continuous churn, RN staffing instability and RN vacancy. All 3 categories were compared to teams with RN stability (i.e., same person in the role for the entire 24-month period). Access measures included: average third-next-available appointment, established patient average wait time in days, urgent care utilization, emergency room utilization, and total inbound-to-outbound PC secure messages ratio.ResultsRN continuous churn within PACTs had a significant impact on third-next-available appointment (b = 3.70, p < 0.01). However, RN staffing instability and vacancy had no significant relationship with any of the access measures. Several risk adjustment variables, including team full-time equivalency, team stability, relative team size, and average team size, were significantly associated with access to health care.ConclusionsTeams are impacted by churn on the team. Adequate staffing and team stability significantly predict patient access primary care services. Healthcare organizations should focus on personnel retention and strategies to mitigate the impact(s) of continuous RN turnover. Future research should examine the relative impact of turnover and stability of other roles (e.g., clerks) and how team members adapt to personnel changes.

Private provider practices and incentives for hypertension management in rural and peri-urban Telangana, India– a qualitative study

Hypertension poses a critical threat to health in India, being the predominant risk factor for mortality and disability. With over 70% of outpatient care being provided by the private sector, our study investigated the practices and incentives of private health providers in screening, diagnosing, treating, monitoring, and counseling hypertension patients in rural and peri-urban India. Conducted from April 2020 to February 2021, the qualitative study involved 46 participants, including various healthcare professionals and patients in three Telangana state districts. Analysis revealed a lack of recognition of hypertension’s gravity among private providers in these areas, leading to inconsistent screening practices and varied diagnostic thresholds, particularly among rural medical practitioners. Both formal and informal providers lacked standardized protocols and follow-up mechanisms, with limited technical knowledge about hypertension observed, especially among rural practitioners who were often the first point of contact. Drug effectiveness, and incentives from pharmaceutical sales representatives influenced prescribing practices. Diagnostic labs also offered financial incentives for patient referrals. Thus, aligning providers’ objectives with patient preferences and public health goals is crucial. To encourage evidence-based hypertension care, the government and NGOs could implement strategies such as tailored incentives, financial rewards, tax benefits, accreditation, and recognition for private healthcare providers. Professional bodies in the private sector should establish programs emphasizing quality assurance and certifications. Future research should focus on designing and testing new models for private sector hypertension service delivery, coupled with targeted interventions to enhance care in rural and peri-urban settings.

A Non‐Iterative Wheel‐Rail Contact Geometry Determination Algorithm and Its Application

AbstractTo ensure a more accurate simulation of the wheel‐rail contact state in vehicle‐track interaction, a non‐iterative contact geometry determination algorithm is proposed. This algorithm decouples lateral movement and roll, independently calculates the minimum wheel‐rail gap on both sides, and overcomes the limitation of simultaneous wheel‐rail contact on both sides. It can be applied to single‐side and two‐side wheel‐rail separation problems. Additionally, by converting track irregularity and rail deformation into the reverse displacement of the wheel, it avoids real‐time calculation of the wheel‐rail spatial position, thereby improving calculation efficiency. The effectiveness of the algorithm is verified through Universal Mechanism software and field measurements. Subsequently, the influence of the measured wheel‐rail profile, rail cant, and rail gauge on the wheel‐rail contact characteristics is analyzed. Finally, vehicle shaking caused by track irregularity and wheel‐rail contact is examined from the perspective of wheel‐rail matching. The study demonstrates that the non‐iterative algorithm is suitable for online simulation by pre‐processing the contact geometry parameters. When the track gauge and rail cant increase, the distribution of wheel‐rail contact points becomes more concentrated. Furthermore, when the excitation frequency of wheel‐rail matching is close to the track irregularity excitation frequency, it causes vibration amplification, resulting in lateral vehicle shaking.

Aggregate migration and self-organisation properties of asphalt mixtures during compaction process

The objective of this investigation is to analyze the migration behaviours and self-organisation properties of aggregate-asphalt particle system. The three-dimensional discrete element dynamic compaction model was established, and the accuracy and reliability were validated by self-developed particle migration tracking test. The evaluation indices of aggregate particles was measured to investigate the migration behaviours of aggregates and its evolution law. The self-organisation behaviours of aggregate-asphalt particle system were explored combined with the contact behaviours. The results indicate that the migration process of aggregate particles can be delimited into three stages of compaction degree lower than 50%, from 50% to 70%, and above 70%. The larger the aggregate size, the more significant the rotation migration. Under the combined effect of migration and contact, the coarse aggregates migrate to find stable contact points to self-organize the skeleton structure. Asphalt mortar fills the voids eliminated to self-organize the dense structure.

Effect of Egg Washing and Hen Age on Cuticle Quality and Bacterial Adherence in Table Eggs

The cuticle covering the outer surface of an eggshell functions as both a physical and chemical barrier against invading microorganisms. Contamination of eggs by microbial pathogens progresses in four stages: bacterial attachment to the egg surface, penetration through the cuticle and eggshell, multiplication within the underlying membranes, and the final stage of contaminating the egg contents. Therefore, it is important to study bacterial count at the first point of contact, i.e., on the surface of the eggs. In this study, we have evaluated the impact of differences in cuticle quality (due to egg washing and hen age) on bacterial load. We compared bacterial adherence on the eggshell surface of white eggs which were either washed (graded) or unwashed (ungraded), collected from Lohmann laying hens of different ages: early (24–28 weeks), mid-lay (44–48 weeks), and late (66–70 weeks). We aimed to determine the impact of hen age and egg washing on differences in cuticle quality and bacterial adherence. Our results indicate that hen age (up to 70 weeks) and commercial egg washing do not significantly impact bacterial adherence on eggshell surfaces. We have developed a novel method using green fluorescent protein (GFP)-expressing Salmonella typhimurium to estimate adherence of bacteria to the eggshell surface, with independent measurement of autofluorescence to quantitate cuticle deposition. S. typhimurium were localized, adhering to cracks visible on the outer cuticle in ungraded eggs, indicating that egg-associated pathogens usually enter the egg interior either through respiratory pores in eggshells or through shell micro-cracks. The results of this study can be utilized to optimize innovative methods for predictive microbiology in order to achieve egg safety.

Water Cultures, water knowledge, water conflicts: Rethinking water in the early modern period. Some notes from the Water Cultures Conference

This note will investigate different ways to understand water in the early modern and modern periods, by taking inspiration from the recent conference The Water Cultures of Europe and the Mediterranean, 1500-1900. Held in Venice on the 13th, 14th and 15th September 2023, the conference was organised by the ERC project The Water Cultures of Italy 1500-1900’s team, composed by Principal Investigator David Gentilcore, together with Gaia Bruno, Oscar Schiavone, Rachele Scuro, Salvatore Valenti, and myself. Given the multiplicity of research questions and methodological approaches mobilised by the conference participants, this paper is of course not an exhaustive review of how various strains of historiography have rethought key questions of the early modern period through the lens of water studies, but will rather offer a series of glimpses into macro areas, which have been divided into ‘Water knowledge’, ‘Water Cultures’, ‘Water conflicts’. These macro areas, which correspond to the various panels of the conference, are of course not separated from each other, instead presenting many points of contact, in terms of themes and methodology. Due to constraints in space and the expertise of author of the present note, not all sessions of the three-day conference have been given equal attention, despite being all included in the discussion.

The emerging role of a Stroke Clinical Nurse Specialist (CNS) in Early Supported Discharged: Developing a pathway for stroke nursing for secondary prevention in the community. A scoping review protocol.

Stroke represents a major source of mortality and morbidity globally. The role of a stroke Clinical Nurse Specialist (CNS) as an expert team member in early supported discharge (ESD) for stroke, is not well defined or described although it is well established in other models of after-hospital and out-reach specialist care in the community. A greater focus has been on patients receiving rehabilitation post-stroke, however there is a need for a more holistic approach to care which clinical nurse specialists can offer to patients as part of ESD. Nurses are often the cohesive point of contact for other after-hospital services, managing many aspects of secondary prevention. The aim of this scoping review is to explore the evidence in relation to the role of the stroke nurse providing secondary prevention interventions to stroke patients in a community setting. We will conduct a scoping review in accordance with the Arksey and O'Malley, 2005 1 scoping review framework and the PRISMA-ScR guidelines to map available literature on the role of the stroke nurse in post-stroke care of patients in the community. The Cochrane Central Register of Controlled Trials and Systematic literature searches including databases MEDLINE, EMBASE, CINAHL, google scholar and grey literature will be searched using keyword searches. Data will be charted and synthesised and a narrative synthesis will be conducted. This scoping review will be used to identify gaps in the current literature and identify areas for future research in the role of the stroke nurse in ESD in relation to secondary prevention for stroke patients and inform the development of a pathway for stroke nursing in ESD.

Potential of elites in consolidation of public opinion in eastern and western approaches

The authors proceed from the classical understanding of the elite as a social group endowed with power and capable of influencing public opinion. The paper represents the examination of the role of elites – political, economic and social – in the formation of public ideas, values and political attitudes. The problem is conditioned, on the one hand, by the intensification of geopolitical confrontation and the formation of polar ideological concepts on both sides of the ocean, on the other hand – by the dynamic change in characteristics of media environment, which lead to increased centrifugal processes and polarization of public opinion on current events, values and ideology. The authors take into account the widely accepted hypothesis of relative homogeneity of elites (Huntington, Sklair) in the sense that cultural differences and stereotypes influence decision-making in this environment the least. This assumption became the starting point in choosing the topic, predetermined the search for possible points of contact in building a public dialogue, and, in general, served as the basis for a conceptual assessment of the ability of elites to resolve insurmountable contradictions between different segments of the political media space. The authors identified similarities and differences in the understanding of the social and political role of elites in the East and West and proposed possible routes for the development of dialogue. The study is based on the works of the classics of the theory of elites, as well as on modern research in the field of social communication and media.

An Innovative, Collaborative, and Transformative Program to Enhance Off-Campus Clinical Faculty Engagement.

Off-campus (volunteer, community-based) clinical faculty, upon whom medical schools heavily depend, are an integral component of medical education. However, challenges hinder their involvement in medical school governance and other activities, including inadequate communication, lack of recognition, high clinical demands that may preclude teaching, and time-consuming non-clinical tasks. While faculty appointments offer benefits like free CME, access to library resources, and email communications, faculty often prioritize potential contributions to their teaching roles over these benefits. Our medical school launched a new initiative to tackle these issues head-on. We established an Office of Faculty Engagement (OFE) that leverages engagement strategies to enhance communication, broaden access to campus resources, and provide tailored rewards for clinicians. We rebranded volunteer clinical faculty as Off-Campus Faculty (OCF) to foster a more interactive relationship and innovative measures, including personalized welcome emails, a dedicated point of contact for OCF, a user-friendly website, regular orientations, faculty development programs, recognition and appreciation events, and exclusive awards. From August 2021 to December 2023, we contacted 587 OCF members; 85 faculty members experienced improved communication. This innovative approach streamlines and personalizes interactions with OCF, enhances their satisfaction, and represents a transformative opportunity to engage and involve OCF in medical education.

Access to primary healthcare services among adults with disabilities in Brazil.

To investigate perspectives of people with disabilities in Brazil regarding the access to primary healthcare. In-depth interviews were conducted with 44 individuals with disabilities in Pernambuco, Distrito Federal, and São Paulo between March 2020 and November 2021. These interviews were transcribed, coded, and analysed thematically, using the Levesque framework to identify healthcare access barriers. Participants expressed a solid understanding of their healthcare needs and existing obstacles. However, individuals with hearing and visual impairments experience challenges because of communication barriers. In Pernambuco, the Community Health Agent was often the initial point of contact for primary care services. Public transportation lacked accessibility, from buses to driver attitudes, posing difficulties for people with disabilities. More accessible transportation and improved urban infrastructure could enhance service access. High medication costs were reported due to limited healthcare unit availability. Communication accessibility issues, inadequate audio-visual resources and equipment were also identified as barriers. Attitudinal barriers among healthcare professionals and subpar home visit services further hinder access. To address these challenges and improve the well-being of individuals with disabilities in Brazil, comprehensive action is essential. This includes leadership, governance, and resource allocation reforms to meet healthcare needs. Initiatives like disability-focused training for service providers, enhanced transportation options, improved information accessibility, and increased support from community healthcare workers can collectively enhance the lives of people with disabilities.

Experimental analysis of wheel and bogie frame transfer functions for on-board measurements of rail roughness

Acceleration measurements on in-service rail vehicles give many valuable insights into track condition. These measurements are favourable in terms of measurement frequency, no need for additional track possession for measurements, operator safety, etc. The collected acceleration data however needs to be further processed to extract more detailed information on rail surface defects. To derive rail roughness from bogie frame acceleration, a complex signal processing approach is required, as well as determining the dynamic parameters of the track, vehicle, and operational conditions. In this paper, a method to evaluate the influence of resilient wheel and bogie frame on the acceleration data received from bogie frame-mounted accelerometers is described. The method is based on a standstill measurement of frequency response functions on wheel and bogie frame positions using an impact hammer and accelerometers. Following the preliminary results of bogie acceleration measurements, in-situ wheel receptance measurements were carried out on the same tramway vehicle in a standstill position, to determine the transfer function between the wheel-rail contact point and the position of the accelerometer mounted on the wheel frame. After the experimental study, a discussion of their potential application in the method for deriving rail roughness from vibration data is presented.

Effect of uncorrelated sources assumption on railway vibration modelling

In classical railway vibrations studies, wheel-rail contact points are considered as point sources uncorrelated from each other. This approach gives a more reliable source for vibration impact assessment studies along railways which can be based on in situ experimental measurements or on numerical models. This is also related to the fact that the combined wheel-rail roughness that cannot be perfectly known. This postulation allows using a line spectral force density combined with a line transfer mobility. However, all sources are generated by the same system (train, railway and ground) and are in reality correlated in some way. This paper investigates the effect of sources decorrelation on ground vibration estimation. Numerical models in time and frequency domain are used allowing comparisons for several identical configurations. Results are discussed in detail to understand the effect of sources uncorrelation approach.

A Fast Grasp Planning Algorithm for Humanoid Robot Hands.

Grasp planning is crucial for robots to perform precision grasping tasks, where determining the grasp points significantly impacts the performance of the robotic hand. Currently, the majority of grasp planning methods based on analytic approaches solve the problem by transforming it into a nonlinear constrained planning problem. This method often requires performing convex hull computations, which tend to have high computational complexity. This paper proposes a new algorithm for calculating multi-finger force-closure grasps of three-dimensional objects based on humanoid multi-fingered hands. Firstly, sufficient conditions for the multi-finger force-closure grasps of three-dimensional objects are derived from a point contact model with friction. These three-dimensional force-closure conditions are then transformed into two-dimensional plane conditions, leading to a simple algorithm for multi-finger force-closure determination. This method is purely based on geometric analysis, resulting in low computational demands and enabling the rapid assessment of force-closure grasps, which are beneficial for real-time applications. Finally, the algorithm is validated through two case studies, demonstrating its feasibility and effectiveness.

Tackling hospital service burden of alcohol dependence in England: a service evaluation of alcohol care teams (ACTs) and care pathways for integrated care

Background Chronic alcohol disorder hospital admissions are increasing in England and present a huge cost to England’s health and social care costs. Hospital-based alcohol care teams (ACTs) aim to better meet these patients’ complex needs through assessment and targeted referral. This has the potential to work effectively within England’s newly established integrated care system. Methods The aim of this project was to identify in what ways ACTs can be effective in improving care pathways for complex care in a whole-system health and social care setting. We conducted semi-structured, tailored interviews with practitioners, managers and commissioners, across three hospital and community settings in one large urban region in England, comparing ACT working with non-ACT working. Results Effective pathways were enabled by the presence of an ACT, multi-agency community initiatives, assertive alcohol outreach and frequent-attender team meetings. Identified barriers were lack of systemic funding and commissioning, poor communication between agencies, lack of information-sharing and insufficient staff training. Conclusion Community outreach and in-reach between hospitals and community services enable effective care pathways when ACTs provide the point of contact. A well-resourced ACT with clear operational remit can create links between diverse agencies and enables improved wraparound care for alcohol dependent patients.

Effects of COVID-19 on Irish general practice activity from 2019 to 2021: a retrospective analysis of 500,000 consultations using electronic medical record data.

General practice (GP) is crucial to primary care delivery in the Republic of Ireland and is almost fully computerised. General practice teams were the first point of contact for much COVID-19-related care and there were concerns routine healthcare activities could be disrupted due to COVID-19 and related restrictions. The study aimed to assess effects of the pandemic on GP activity through analysis of electronic medical record data from general practice clinics in the Irish Midwest. A retrospective, descriptive study of electronic medical record data relating to patient record updates, appointments and medications prescribed across 10 GP clinics over the period 2019-2021 inclusive. Data relating to 1.18 million record transactions for 32k patients were analysed. Over 500k appointments were examined, and demographic trends presented. Overall appointment and prescribing activity increased over the study period, while a dip was observed immediately after the pandemic's arrival in March 2020. Delivery of non-childhood immunisations increased sixfold as a result of COVID-19, childhood immunisation activity was maintained,while cervical smears decreased in 2020 as the screening programme was halted. A quarter of consultations in 2020 and 2021 were teleconsultations, and these were more commonplace for younger patients. General practice responded robustly to the pandemic by taking on additional activities while maintaining routine services where possible. The shift to teleconsulting was a significant change in workflow. Analysing routinely collected electronic medical record data can provide valuable insights for service planning, and access to these insights would be beneficial for future pandemic responses.

Preoperative tibiofemoral contact point on standing lateral radiograph predicts anteroposterior knee kinematics in total knee arthroplasty

AbstractPurposeThis study investigated the tibiofemoral contact point (CP) on standing lateral radiographs in knee osteoarthritis and assessed the relationship between CP and pre‐ and postoperative knee kinematics in total knee arthroplasty (TKA).MethodsThe intraoperative knee status of 46 knees with varus deformity that underwent bicruciate stabilized TKA using a navigation system was investigated. The intraoperative anteroposterior (AP) position of the femur relative to the tibia at maximum extension, 15°, 30°, 45°, 60° and 90° was evaluated by the navigation system before and after TKA. The CP, defined as the CP between the femur and tibia, was assessed on standing lateral radiographs at the maximum extension of the knee before and 1 year after TKA. CP was expressed as the ratio of tibial plateau distance on a scale of 0–1, with 0 indicating the most anterior position of the femur relative to the tibia.ResultsThe mean CP on standing lateral radiographs was 0.54 ± 0.12 and 0.46 ± 0.08 before and after TKA, respectively. The postoperative CP was significantly more anterior than the preoperative CP (p = 0.0002). The mean AP position of the femur relative to the tibia moved anteriorly during early knee flexion both before and after TKA, representing nonanatomical AP movement. The preoperative posterior CP group (CP &gt; 0.54) showed more nonanatomical AP movement from 15° to 60° before and after TKA compared with the preoperative anterior CP group (CP &lt; 0.54).ConclusionPreoperative posterior deviation of the femur relative to the tibia in the standing position was a predictive factor for nonanatomical AP knee kinematics. Biomechanical analysis of postoperative knees will be necessary; however, surgeons should focus on preoperative tibiofemoral CP on standing lateral radiographs to predict knee kinematics.Level of EvidenceLevel Ⅲ.