Coffee Consumption Research Articles

Mapping the distribution of bioactive compounds and aroma/flavour precursors in green coffee beans with an integrated mass spectrometry-based approach

Abstract Coffee is one of the most enjoyed beverages worldwide and whilst a wide array of secondary metabolites has been qualitatively and quantitatively characterised within the coffee bean, little is known about their distribution in different bean tissues. In this work, complementary mass spectrometry (MS) based approaches were utilised to determine the spatial metabolomic content of coffee beans, focusing on highlighting those which presented a regiospecific distribution and distinguished the different endosperm regions and the embryo. Preliminary exploration of the spatial metabolome of Coffea arabica coffee beans highlighted tissue-specific molecular features through an unsupervised statistical analysis. Then, the complementary information derived from higher resolution MS approaches resulted in the annotation of 13 metabolites which showed a specific enrichment in at least one tissue, and most of these were noted to be bioactive compounds or aroma/flavour precursors. Knowledge of the tissue distribution of these compounds could shed light on their biological role in plant physiology and bean development, but could also have relevant implications for their positive impact on human health due to coffee consumption as well as their possible effect on aroma and flavour upon roasting of green coffee beans.

The Multidisciplinary Approach in the Management of Patients with Kidney Stone Disease-A State-of-the-Art Review.

Kidney stone disease has a multifactorial etiology, and evolving dietary habits necessitate continuous updates on the impact of dietary components on lithogenesis. The relationship between diseases influenced by lifestyle, such as obesity and diabetes, and kidney stone risk underscores the need for comprehensive lifestyle analysis. Effective management of kidney stones requires a multidisciplinary approach, involving collaboration among nutritionists, urologists, nephrologists, and other healthcare professionals to address the complex interactions between diet, lifestyle, and individual susceptibility. Personalized dietary therapy, based on each patient's unique biochemical and dietary profile, is essential and necessitates comprehensive nutritional assessments. Accurate dietary intake evaluation is best achieved through seven-day, real-time dietary records. Key factors influencing urinary risk include fluid intake, dietary protein, carbohydrates, oxalate, calcium, and sodium chloride. Personalized interventions, such as customized dietary changes based on gut microbiota, may improve stone prevention and recurrence. Current research suggests individualized guidance on alcohol intake and indicates that tea and coffee consumption might protect against urolithiasis. There is potential evidence linking tobacco use and secondhand smoke to increased kidney stone risk. The effects of vitamins and physical activity on kidney stone risk remain unresolved due to mixed evidence. For diseases influenced by lifestyle, conclusive evidence on targeted interventions for nephrolithiasis prevention is lacking, though preliminary research suggests potential benefits. Management strategies emphasize lifestyle modifications to reduce recurrence risks, support rapid recovery, and identify predisposing conditions, highlighting the importance of these changes despite inconclusive data.

Enhancing social enterprise coffee marketability through sensory packaging: consumer impressions, willingness to buy, and gender differences

PurposeThis study investigates how consumers perceive the packaging of Philippine coffee social enterprise products and how this impression affects their willingness to purchase based on sensory expectations, brand attitude, product quality perception, and price perception.Design/methodology/approachFollowing a positivist research philosophy, this study used empirical methods, surveying 263 coffee consumers. The coffee packaging prototypes varied across material and graphic designs. The data was analyzed statistically using the Friedman test and Spearman correlation.FindingsIt was found that packaging elements elicit an equal share of emotional responses. Graphics have a greater impact than materials. Females are more affected by visuals, while materials influence males more. Further, packaging design correlates positively and significantly with consumer impressions and willingness to buy.Research limitations/implicationsThe sampling methodology limits generalizability. Future studies can use integrated models to analyze the effects of additional packaging variables like color and shape.Practical implicationsCoffee enterprises should focus on graphic rather than material elements. Paper packs with patterned graphics are most attractive to consumers. Targeted gender-sensitive packaging designs are needed. Standardized packaging can help build the Philippine coffee social enterprise industry and support small-scale farmer livelihoods. Environmentally sustainable materials should be prioritized.Social implicationsThe findings contribute to the success and growth of small-scale farmers and social enterprises in the Philippines. These businesses can attract more consumers, increase their market share, and ultimately generate more significant social impact by implementing packaging design strategies that effectively communicate product quality, sustainability, and social value.Originality/valueThe study uniquely integrates diverse methods to provide holistic insights into jointly analyzing the effects of packaging materials and graphics. It proposes an expanded conceptual role of packaging in shaping product perceptions using the affective response framework and Kansei approach.

Metabolic shifts during coffee consumption refresh the immune response: insight from comprehensive multiomics analysis.

Coffee, a widely consumed beverage, has shown benefits for human health but lacks sufficient basic and clinical evidence to fully understand its impacts and mechanisms. Here, we conducted a cross-sectional observational study of coffee consumption and a 1-month clinical trial in humans. We found that coffee consumption significantly reshaped the immune system and metabolism, including reduced levels of inflammatory factors and a reduced frequency of senescent T cells. The frequency of senescent T cells and the levels of the senescence-associated secretory phenotype were lower in both long-term coffee consumers and new coffee consumers than in coffee nondrinking subjects, suggesting that coffee has anti-immunosenescence effects. Moreover, coffee consumption downregulated the activities of the The Janus kinase/signal transduction and activator of transcription (JAK/STAT) and mitogen-activated protein kinases (MAPK) signaling pathways and reduced systemic proinflammatory cytokine levels. Mechanistically, coffee-associated metabolites, such as 1-methylxanthine, 3-methylxanthine, paraxanthine, and ceramide, reduced the frequency of senescent CD4+CD57+ T cells in vitro. Finally, in vivo, coffee intake alleviated inflammation and immunosenescence in imiquimod-induced psoriasis-like mice. Our results provide novel evidence of the anti-inflammatory and anti-immunosenescence effects of coffee, suggesting that coffee consumption could be considered a healthy habit.

An outline of the management and prevention of postoperative ileus: A review.

Postoperative ileus (POI) is a prevalent surgical complication, which results in prolonged hospitalization, patient distress, and substantial economic burden. The literature aims to present a brief outline of interventions for preventing and treating POI post-surgery. Data from 2014 to 2023 were gathered from reputable sources like PubMed, PubMed Central, Google Scholar, Research Gate, and Science Direct. Inclusion criteria focused on studies exploring innovative treatments and prevention strategies for POI, using keywords such as novel POI treatments, non-pharmacological prevention, POI incidence rates, POI management, and risk factors. The findings revealed that integration of preventive measures such as coffee consumption, chewing gum, probiotics, and use of dikenchuto within enhanced recovery programs has significantly reduced both the frequency and duration of POI, without any adverse effects, with minimally invasive surgical approaches showing promise as an additional preventive strategy. While treatment options such as alvimopan, NSAIDs, and acupuncture have demonstrated efficacy, the use of lidocaine has raised concerns due to associated adverse effects. The ongoing exploration of novel therapeutic strategies such as targeting the mast cells, vagal nerve stimulation and tight junction protein, and prokinetic-mediated instigation of the cholinergic anti-inflammatory trail not only holds promise for enhanced treatment but also deepens the understanding of intricate cellular and molecular pathways underlying POI. POI presents a complex challenge in various surgical specialties, necessitating a multifaceted management approach. The integration of preventive and treatment measures within enhanced recovery programs has significantly reduced POI frequency and duration.

Strategi Pengembangan UKM Kakaku Coffee dengan Metode Analisis SWOT

The coffee shop industry in Indonesia is experiencing rapid growth, driven by the cultural tradition of coffee consumption and the transformation of digital-based businesses. Kakaku Coffee, founded by Fitra Alhady in 2020 in East Jakarta, is a successful example of a coffee shop that combines high-quality coffee with an authentic Japanese cultural concept. Despite achieving initial success, Kakaku Coffee faces challenges such as long service times and limited parking space. This study aims to formulate a comprehensive development strategy for Kakaku Coffee using SWOT analysis. By identifying the internal and external factors affecting Kakaku Coffee's performance, this study provides practical and applicable recommendations. The method used is descriptive qualitative research with purposive and snowball sampling techniques. The analysis results show five strengths, five weaknesses, four opportunities, and three threats faced by Kakaku Coffee, along with applicable TOWS strategies. This research is expected to serve as a reference for other SMEs looking to adopt similar strategies in a competitive industry.

Analysis of the Impact of Coffee Consumption on Adolescent Cardiovascular Performance: An Observational Study in the Adolescent Community in Jakarta, Indonesia

Introduction: Coffee is a popular drink among adolescents. However, its effect on cardiovascular performance in this population remains unclear. This study aims to analyze the relationship between coffee consumption and cardiovascular performance in adolescents in Jakarta, Indonesia. Methods: Cross-sectional observational research was conducted on 350 adolescents aged 15-18 years in Jakarta. Coffee consumption data was collected through a structured questionnaire, while cardiovascular performance was assessed through measurements of blood pressure, heart rate and body mass index (BMI). Logistic regression analysis was used to identify the association between coffee consumption and cardiovascular performance, with adjustment for potential confounding factors. Results: The results of this study provide evidence that excessive coffee consumption (>2 cups/day) can increase blood pressure and resting heart rate in adolescents. However, moderate coffee consumption (1-2 cups/day) does not appear to have a significant negative impact on cardiovascular performance. Conclusion: Excessive coffee consumption (>2 cups/day) has a significant negative impact on adolescents' cardiovascular performance, namely increasing blood pressure and resting heart rate. However, further research is needed to understand the long-term effects and mechanisms underlying this relationship.

Modifiable factors associated with Huntington's disease progression in presymptomatic participants.

Huntington's disease (HD) is a neurodegenerative disorder characterized by progressive motor, cognitive, and psychiatric symptoms. Our aim here was to identify factors that can be modified to slow disease progression even before the first symptoms appear. We included 2636 presymptomatic individuals (comparison with family controls) drawn from the prospective observational cohort Enroll-HD, with more than 35 CAG repeats and at least two assessments of disease progression measured with the composite Huntington's disease rating Scale (cUHDRS). The association between sociodemographic factors, health behaviors, health history, and cUHDRS trajectory was assessed with a mixed-effects random forest using partial dependence plots and Shapley additive explanation method. Participants were followed by an average of 3.4 (SD = 1.97) years. We confirmed the negative impact of age and a high number of CAG repeats. We found that a high level of education, a body mass index (BMI) <23 kg/m2 before the age of 40 and >23 kg/m2 thereafter, alcohol consumption of <15 units per week, current coffee consumption and no smoking were linked to slow disease progression, as did no previous exposure to antidepressants or anxiolytic, no psychiatric history or comorbidities, and being female. Other comorbidities or marital status showed no major association with HD evolution. Reducing modifiable risk factors for HD is one way to support the presymptomatic population. A high level of education, low-to-moderate alcohol consumption, no smoking, and BMI control are likely to slow disease progression in this population.

Environmental and economic sustainability assessment of the production and consumption of different types of coffee in the UK

The need for more sustainable production and consumption of coffee has received global attention, as coffee is one of the most consumed beverages in the world. In an effort to help address this need, this study uses life cycle assessment, life cycle costing and multi-criteria decision analysis to evaluate its environmental and economic sustainability and identify the most sustainable coffee drink(s). Nine coffee drinks are evaluated: espresso, latte, cappuccino, Americano, drip-filter, coffee pod, spray- and freeze-dried instant, and instant coffee mix. To determine the sustainability of coffee from different consumption perspectives, three functional units are considered: one serving of coffee, 1 L of coffee, and 100 mg of caffeine. The system boundaries are from cradle to grave, comprising cultivation of green coffee beans, coffee production, transportation, consumption of coffee, and end-of-life waste management. The results show that the sustainability ranking of different coffee drinks changes depending on the functional unit considered. Instant coffee has the lowest environmental impacts and costs for the functional unit of one serving and 1 L of coffee, while coffee pods are the best option for the functional unit of 100 mg of caffeine. Espresso is the worst alternative for 1 L of coffee and latte is the least sustainable for the functional unit of one serving and 100 mg of caffeine. For all types of coffee and all functional units considered, cultivation of green coffee beans and milk production are the main hotspots for all impacts and costs, contributing 48–99.7 %. These findings will be of interest to the coffee industry, consumers, policy makers and other stakeholders interested in sustainable production and consumption of coffee.

Physicochemical and sensory analysis of mangrove seed coffee (Sonneratia ovata) compare with robusta coffee from Indonesian origin

Coffee is a global drink for millennials. Indonesia is one of the countries with the most significant coffee consumption in the world. The main problem with coffee consumption is the caffeine content, many researchers are looking for alternative coffee drinks that do not contain caffeine, one of which is mangrove fruit seeds. Caffeine can be removed during roasting, but over-roasting produces unwanted sensory impacts on coffee. This study aimed to determine mangrove coffee beans' sensory characteristics and caffeine content to compare with robusta coffee as commercial coffee. In addition, it is also necessary to monitor changes in the properties of the mixture of Robusta coffee beans and mangrove seeds during the roasting process in real-time. The method used was a randomized block design, using two factors, commercial coffee (C) and mangrove seed coffee (M), and 3 test levels, light (L) at 193°C to 199°C, medium (M) at 204°C and dark roast (D) at 213°C to 221°C. Analysis of data using Analysis of variance (ANOVA). Significantly different test results were then tested using Duncan's advanced test. Data processing was carried out using SPSS Version 28 software. The results showed that the sensory characteristics of commercial coffee (Robusta) were preferable to mangrove coffee, but the impact of caffeine could be eliminated by consuming mangrove coffee. The degree of roasting greatly affects coffee's sensory and chemical quality, with the best results obtained in commercial coffee roasted at a medium level (M) at 204°C. The comparison results showed that the characteristics of coffee between commercial coffee (Robusta) and mangrove coffee have phenol content, total acid, and proximate and sensory values close to commercial coffee. However, the caffeine content is not found in mangrove coffee, so coffee connoisseurs can use mangrove coffee because it can be used as an alternative to coffee drinks without giving the effect of caffeine addiction.

Insights into Gut Microbiome Composition in Hidradenitis Suppurativa: A Comprehensive Examination of Dietary Habits and Environmental Influences.

This study explores the relationship between dietary habits, environmental influences, and gut microbiome composition in individuals with hidradenitis suppurativa (HS), a chronic inflammatory skin condition. A cohort of 80 participants, equally divided into HS patients and healthy controls, was assessed through comprehensive questionnaires capturing demographics, dietary habits, and other health-related information. Fecal samples were collected and analyzed using next-generation sequencing to examine microbiome composition. Despite previous studies suggesting gut dysbiosis in HS, this research found no significant differences in alpha-diversity and Shannon diversity index between the groups. However, significant disparities in dietary habits were observed, with HS patients showing higher sugar and milk consumption. The study also identified a significant correlation between coffee consumption and the presence of certain bacterial genera. While the study did not reveal major differences in microbiome diversity, the findings on dietary habits and specific microbiome components suggest potential targets for therapeutic intervention. These results underscore the importance of further research into the gut-skin axis and its role in HS, aiming to enhance management strategies through dietary modifications and lifestyle interventions.

Comprehensive insights on treatment modalities with conventional and herbal drugs for the treatment of duodenal ulcers.

Areas of the body accessible to gastric secretions, such as the stomach and duodenum, are most commonly damaged by circumscribed lesions of the upper gastrointestinal tract mucosa. Peptic ulcer disease is the term for this illness (PUD). About 80% of peptic ulcers are duodenal ulcers, with stomach ulcers accounting for the remaining 20%. Duodenal ulcers are linked to the two primary results about Helicobacter pylori infection and COX inhibitor users. Additional causes might include drinking, smoking, stress, and coffee consumption. The indications and symptoms of a duodenal ulcer depend on the patient's age and the lesion's location. For duodenal ulcers, proton pump inhibitors (PPIs) are the usual course of treatment. This comprehensive study included an in-depth literature search in the literature and methods section using electronic databases such as PubMed, ScienceDirect, and Google Scholar. The search method included publications published from the inception of the relevant database to the present. Inclusion criteria included studies investigating different treatment options for duodenal ulcer disease, including traditional pharmacotherapy and naturopathic treatments. Data mining includes information on treatment techniques, treatment outcomes, and possible synergies between conventional and herbal treatments. In addition, this review critically examines the available information on the effectiveness, safety, and possible side effects of different treatments. The inclusion of conventional and herbal treatments is intended to provide a comprehensive overview of the many treatment options available for duodenal ulcer disease. A more comprehensive and personalized treatment plan can be achieved by incorporating dietary changes, lifestyle modifications, and, if necessary, herbal therapies to complement other treatments normally.

Role of Environmental Risk Factors in the Etiology of Inflammatory Bowel Diseases: A Multicenter Study.

The increasing global incidence and prevalence of inflammatory bowel disease (IBD) necessitates an investigation into the potential influence of environmental risk factors on its origin. This multicenter case-control study aimed to investigate potential environmental risk factors contributing to IBD development in Turkey. The study included 156 Crohn's disease (CD), 277 ulcerative colitis (UC) patients, and 468 controls (matched for age and gender) from six hospitals' gastroenterology departments. Data collection relied on the International Organization of IBD's questionnaire on environmental factors. Each environmental factor was initially analyzed using univariate and subsequently multivariate logistic regression models. In the multivariate model, regular coffee consumption was associated with decreased odds for both CD (OR 0.28; 95% CI 0.14-0.55) and UC (OR 0.25; 95% CI 0.15-0.42). Stress was associated with UC (OR 3.27; 95% CI 1.76-6.10) and CD (OR 4.40; 95% CI 2.12-9.10) development. A history of childhood infectious diseases (gastroenteritis, upper respiratory tract infections, etc.) raised the odds for both CD (OR 9.45; 95% CI 2.51-35.6) and UC (OR 7.56; 95% CI 1.57-36.4). Conversely, consuming well/spring water (OR 0.22; 95% CI 0.10-0.50) and childhood antibiotic use (OR 0.41; 95% CI 0.18-0.93) showed a positive association against UC. Increased consumption of refined sugar and industrial food products emerged as risk factors for IBD. Smoking increased the risk for CD (OR 2.38; 95% CI 1.16-4.91), while ex-smoking increased the risk for UC (OR 3.16; 95% CI 1.19-8.37). This study represents the first multicenter case-control study in Turkey examining the effects of environmental factors on IBD. It revealed that coffee consumption is positively associated, while stress and childhood infection-related diseases are risk factors. These findings, which are not supported by other studies, provide insight into the relationships between these factors and IBD.

Perceptions and motivational factors of Chinese coffee consumers towards robot baristas: a Technology Acceptance Model 2 perspective

PurposeThis study aims to explore the attitudes and perceptions of Chinese coffee consumers towards robot baristas, considering the proliferation of automated entities within China's coffee sector.Design/methodology/approachEmploying the extended Technology Acceptance Model 2 as its theoretical framework, this research conducts in-depth interviews with 30 Chinese coffee consumers. The laddering technique is utilized, supplemented by video simulation. Thematic analysis is subsequently employed to scrutinize the data.FindingsThe findings delineate six pivotal themes encapsulating Chinese coffee consumers' perceptions of robot baristas – Perceived Introvert Friendliness, Perceived Novelty, Perceived Intellectual Discrepancies, Perceived Efficiency and Reliability, Perceived Emotional Disconnection, and Perceived Labour Market Disruption. Moreover, six motivational themes are identified - Social Status Boosting, Openness to Experience, Ease of Use, Tech-Driven Affordability, Reliable and Uncompromising Quality, and Resistance to Overbearing Service.Research limitations/implicationsThe study is limited by its focus on a specific cultural context. Future research could explore cross-cultural perspectives.Practical implicationsThe findings of this study offer guidance on how to market and position robotic barista services to appeal to consumer preferences and drive adoption.Social implicationsUnderstanding consumer perceptions of robotic baristas has broader social implications, particularly in terms of labour market disruption and the potential impact on traditional coffee professions. Businesses can navigate the social implications of automation more effectively and foster greater acceptance of technological innovations within society.Originality/valueThis study offers insights into the inclinations of Chinese coffee consumers, thereby facilitating informed decision-making and the formulation of effective strategies to expedite the adoption of robotic service.

THE RELATIONSHIP BETWEEN COFFEE CONSUMPTION AND SLEEP QUALITY WITH THE INCIDENCE OF ACNE VULGARIS

Acne vulgaris, or acne, was a common skin problem that occurred in adolescents and young adults, and had a significant psychological impact, especially on individual self-confidence. The high prevalence of this issue, along with factors such as dietary patterns, sleep habits, and coffee consumption, led to a need for deeper understanding of its relationship with skin conditions. This study aimed to evaluate the association between coffee consumption and sleep quality with the occurrence of acne vulgaris. The research method used a quantitative approach with a survey design and descriptive correlational method in a cross-sectional research approach. The instruments included a coffee consumption questionnaire with a Cronbach’s alpha value of 0.707 and a PSQI (Pittsburgh Sleep Quality Index) questionnaire with a Cronbach’s alpha value of 0.888. The study sample consisted of students from Universitas Pendidikan Indonesia Kampus Sumedang who experienced acne problems, frequently consumed coffee, and had insufficient sleep hours. Data collection was conducted through questionnaires that covered information about coffee consumption patterns and types of coffee consumed, as well as sleep patterns. The research results indicated that there was no significant relationship between coffee consumption and the occurrence of acne vulgaris, with a p-value of 0.106 (&gt;0.05). However, there was a significant association between sleep quality and the occurrence of acne vulgaris, with a p-value less than 0.001. The conclusion from this study was that coffee did not directly impact the growth of acne, but poor sleep quality could directly affect acne occurrence. Further research is expected to explore other factors that may cause acne vulgaris.

Migraine incidence and coffee consumption among child-bearing age women: the Korea Nurses’ Health Study

This longitudinal study aimed to identify factors that influence migraines in Korean women nurses using data from the Korea Nurses’ Health Study. Among those who participated in Survey 1 (2013–2014) and the follow-up survey (2015–2019), we selected 2605 participants for Cox proportional hazard regression analysis, 521 participants who were newly diagnosed with migraine and 2084 controls using a 1:4 incidence density sampling approach. Consuming coffee (≥ 3 cups: RR = 1.666; 95% CI = 1.175–2.362, < 3 cups: RR = 1.439; 95% CI = 1.053–1.966), being obese (BMI ≥ 25: RR = 1.341, 95% CI = 1.003–1.793), and engaging in vigorous physical activity (RR = 1.010; 95% CI = 1.000–1.019) increased the risk of developing a migraine. Nurses with an annual salary greater than $3500 were less likely to develop migraines (RR = 0.786, 95% CI = 0.631–0.979). The results imply that lifestyle factors, such as the amount of coffee consumption, BMI level, and degree of physical activity could be considered when formulating treatment plans for women who have newly developed migraines.

Does Perceived Value Moderate the Influence of Brand Image and Hedonic Lifestyle on Purchasing Decisions? Case: Starbucks Brand Coffee Consumer

Does Perceived Value Moderate the Influence of Brand Image and Hedonic Lifestyle on Purchasing Decisions? Case: Starbucks Brand Coffee Consumer

Excessive caffeine use and its consequence on mental illness: a cross-sectional study in Indonesia

Abstract Coffee is one of the most popular beverages globally. People often drink coffee for its caffeine content and its stimulating effects. However, excessive coffee consumption, like any other dietary or behavioral excess, can negatively affect physical and mental health. This study investigates the association between excessive coffee use and mental problems. A cross-sectional study was conducted among 392 respondents in Aceh, Indonesia. Excessive coffee use was measured using a questionnaire, while mental illness was screened using DASS-21. Other sociodemographic variables were also examined and treated as possible predictors. The prevalence of excessive coffee use (&gt;400 mg per day) was 15.6%. The prevalence of depression was 23.2%, anxiety was 40.8%, and stress was 12.8%. The amount of caffeine consumption was correlated with depression (rs = 0.11, p = 0.01), anxiety (rs = 0.13, p = 0.001), and stress (rs = 0.14, p = 0.001), indicating that as the amount of coffee consumption increased, the score of mental problem also increased. The study established a noteworthy correlation between caffeine intake and mental health, suggesting that as coffee consumption increased, so did the scores for depression, anxiety, and stress. These findings underscore the importance of considering coffee consumption habits and their potential impact on mental well-being in clinical and public health contexts.

The Effect of Shift Work on Sleep Patterns of Paramedics in Saudi Arabia.

Shift work poses significant sleep health challenges for paramedics, affecting their ability to respond effectively in emergencies. This study aimed to evaluate the impact of shift work on sleep parameters among paramedics in Saudi Arabia, identifying key factors influencing insomnia. A cross-sectional, online survey was conducted, gathering data on sociodemographic characteristics, work-related factors, sleep duration, and insomnia among paramedics in Saudi Arabia. The Athens Insomnia Scale was used to define insomnia. The association between shift work and sleep parameters was examined. Predictors of insomnia were identified through logistic regression models by inspecting the adjusted odds ratio (aOR). 1076 Saudi paramedics were included, most of whom were 26-35 years old, males, married, had a Bachelor's degree, worked in hospital-based settings for private agencies in rural areas, and had 6-10 years of experience. Occupational stress was reported by 52.96% of paramedics. All shift work characteristics (working hours, number of shifts, work schedule, and off-work days) were significantly associated with insomnia (p=0.0001). The multivariate regression revealed that work setting (aOR=18.71, p=0.02), coffee consumption (aOR=36.83, p=0.01), work schedule (aOR=21.93, p=0.01), and time to bed (aOR=0.01, p=0.01), sleep duration (aOR=0.03, p=0.03), and occupation stress (aOR=9.31, p=0.001) were predictors for insomnia. Our findings underscores the need for targeted interventions to mitigate the adverse effects of shift work on sleep health among paramedics.

Optimization of coffee vinegar production from cherry Pulp as by product of arabica coffee processing

Abstract The current high consumption of coffee globally has an impact on the abundance of by-products of coffee processing in the form of cherry pulp which are considered waste and cause environmental problems. The waste from arabica coffee is potential economic value products such as fermented vinegar because of its rich nutrients. The aim of this research was to determine the optimal conditions for acetic acid fermentation and the influence of yeast concentration and nitrogen sources fermented for 60 days. The research was carried out in two stages of fermentation using the Orleans method. Anaerobic alcohol fermentation (20 days) followed by aerobic acetic acid fermentation (40 days). A Randomized Block Factorial Design was used with 2 factors, namely yeast concentration (S15% and S210%) and NPK (N10g, N25g, and N310g), repeated 3 times. Observations on alcoholic fermentation were carried out every 5 days for 20 days regarding ethanol levels. Meanwhile, in acetic acid fermentation, 2.5% vinegar starter was added for each treatment and observations were made every 10 days for 40 days regarding the yield, acetic acid content, pH value and total dissolved solids. The results showed that the highest formation of acetic acid was obtained on day 30 of fermentation. The highest acetic acid content was obtained in the treatment S210%: N25g of 5.27%, pH value of 3.46, TSS value of 0.49 °Bx with a total yield of 42.93%. This is in line with the ethanol content previously formed on day 20 of 11.04% in the same treatment. This value meets the quality standards for fermented vinegar according to SNI 01-4371-1996 by at least 4%.