Construct Of Impulsivity Research Articles

Compulsive buying disorder: Conceptualization based on addictive, impulsive, and obsessive-compulsive features and comorbidity

BackgroundThis study sought to examine the conceptualization of compulsive buying disorder in a sample of adults drawn from the community and its associated mental health correlates. MethodsAn online survey of “Personality, Mental Health, and Well-Being” was distributed to 300 adults aged 18–75 years. The survey measured a range of behaviors, such as buying behavior, alcohol and drug use, impulse control disorders, and dimensional constructs of impulsivity and obsessive-compulsiveness. ResultsA total of 294 participants (54.7% female) completed the survey and were included in the analysis. The overall frequency of probable compulsive buying disorder was 5.4% (n = 16). Compared to adults without compulsive buying disorder, those with probable compulsive buying disorder were significantly less likely to identify as heterosexual and were significantly more likely to endorse attention-deficit hyperactivity disorder, drug use problems, symptoms of borderline personality disorder, binge eating disorder, and had higher levels of compulsivity plus impulsivity. ConclusionCompulsive buying disorder appears to be fairly common in adults and appears to have symptom or diagnostic overlap with obsessive-compulsive problems, addictive disorders, and impulse control disorders. Findings highlight the need for careful clinical screening to identify often overlooked comorbidities and treat them on an individual patient basis, as well as the need to conduct high-quality clinical trials for compulsive buying disorder itself and to explore its presentation longitudinally at large scale.

The Androgen Dehydroepiandrosterone Sulfate Shows a Greater Relationship with Impulsivity than Testosterone in a Healthy Male Sample.

This study was designed to examine the relationships among the impulsivity construct as a personality trait, the dehydroepiandrosterone sulfate (DHEA-S), and testosterone in a sample of 120 healthy middle-aged males (Mage = 44.39; SD = 12.88). The sum of the three BIS-11 scales, the SR, and the five UPPS-P scales correlated with DHEA-S 0.23 (p < 0.006) and testosterone 0.19 (p < 0.04), controlling for age. Partial correlations showed that DHEA-S was significantly related to motor impulsivity (0.24; p < 0.008), Sensitivity to Reward (0.29; p < 0.002), Lack of Premeditation (0.26; p < 0.05), and, to a lesser extent, Sensation Seeking (0.19; p < 0.04) and Positive Urgency (0.19; p < 0.04). Testosterone correlated with attention impulsivity (0.18; p < 0.04), Sensation Seeking (0.18; p < 0.04), and Positive Urgency (0.22; p < 0.01). Sensitivity to Reward, Negative Urgency, and Positive Urgency were significant predictors of DHEA-S (R2 = 0.28), and Positive Urgency for testosterone (R2 = 0.09). Non-parametric LOESS graphical analyses for local regression allowed us to visualize the non-linear relationships between the impulsivity scales with the two androgens, including non-significant trends. We discuss the implications of these results for impulsive biological personality traits, the limitations of our analyses, and the possible development of future research.

Altered Impulsivity Across Drug-Naïve Parkinsonism, Isolated Rapid Eye Movement Sleep Behavior Disorder, and Their High-Risk Relatives.

To determine multidimensional impulsivity levels across different early stages of α-synucleinopathy. This cross-sectional study investigated motor and decisional impulsivity levels using a panel of computerized tasks among drug-naïve parkinsonism patients, isolated/idiopathic rapid eye movement sleep behavior disorder (iRBD) patients and their first-degree relatives (iRBD-FDRs), and control participants. Trait impulsivity and impulse control behaviors were assessed by self-reported questionnaires. A total of 27 drug-naïve parkinsonism patients, 157 iRBD patients, 66 iRBD-FDRs, and 82 control participants were recruited. Parkinsonism and iRBD patients had fewer numbers of extracted beads in beads task 1 and 2 (both p < 0.001), and a higher rate of irrational choice in task 1 (p = 0.046) before making decisions, and fewer numbers of pumps of unexploded blue balloons in the balloon analog risk task (p = 0.004) than control participants, indicating a higher level of reflection impulsivity and a lower level of risk taking, respectively. iRBD patients had more no-go errors in the go/no-go task than control participants (padjusted = 0.036), suggesting a higher level of motor impulsivity. iRBD-FDRs with dream-enactment behaviors had fewer numbers of extracted beads (p = 0.047) in beads task 2 than FDRs without dream-enactment behaviors, suggesting a possible higher level of reflection impulsivity. A complex construct of altered impulsivity with decreased risk taking, but increased reflection and motor impulsivity, has already occurred at the prodromal and early stages of α-synucleinopathy, which have implications for underlying pathophysiology and clinical management of α-synucleinopathy, especially for impulse control behaviors upon dopaminergic drug treatment. ANN NEUROL 2024;95:544-557.

Taking Another Look at the Pornography Problems Due to Moral Incongruence Model: Does Gender Play a Role?

The pornography problems due to moral incongruence (PPMI) model is a premier framework for understanding problematic pornography use (PPU). However, past studies have generally examined men or entered gender as a covariate in primary analyses. Such approaches mask between-gender differences. Additionally, dysregulation constructs are also thought to be relevant to PPU, yet it is unclear the degree to which they incrementally predict PPU beyond moral incongruence constructs in non-pathological populations. We addressed these gaps by gathering a large sample of college students (n = 295 men, n = 838 women). Analyses with pornography users (n = 251 men, n = 407 women) were consistent with the PPMI model, adjusted for pornography use frequency. Findings did not change when dysregulation constructs of impulsivity and emotional resilience were added to the model. No paths significantly differed between genders. Altogether, among college student pornography users, religiosity was strongly positively correlated with moral disapproval (β = .65 men, β = .62 women), moral disapproval was moderately positively correlated with PPU (β = .41 men, β = .29 women), religiosity was initially moderately positively correlated with PPU (r = .21 men, r = .22 women), but became non-significant in the full model (β = - .21 men, β = - .04 women), and indirect effects of religiosity to PPU through moral disapproval were significant (indirect β = .27 men, β = .18 women). None of the dysregulation constructs significantly predicted PPU. The full model accounted for 23-22% of the PPU variance in men and women, respectively. Implications, future directions, and limitations are discussed.

Mediating effects of impulsivity and alexithymia in the association between traumatic brain injury and aggression in incarcerated males.

Studies suggest both alexithymia and impulsivity (partially) explain aggressive behavior in traumatic brain injury (TBI) patients, but none of these studies use both questionnaire and performance-based measures as recommended, nor simultaneously investigate both impulsivity and alexithymia. The available studies therefore likely miss part of the constructs of alexithymia and impulsivity, and do not comprehensively assess the mediating effects of both constructs in the relationship between TBI and aggression. A sample of N = 281 incarcerated individuals were recruited from Dutch penitentiary institutions, and completed the Buss Perry Aggression Questionnaire (aggression), BIS-11 (impulsivity) and Toronto Alexithymia Scale-20 (alexithymia) questionnaires, as well as a stop-signal task and an emotion recognition paradigm. Several multiple mediation analyses were conducted using structural equation modelling, to assess the viability of a causal theoretical model of aggression. The final planned models were the original models with a good fit with the data (comparative fit index > 0.95, root mean square error of approximation and Standardized root mean square residual < 0.05), and results indicate that only questionnaire-based impulsivity mediated the relationship between TBI and aggression. TBI was unrelated to alexithymia, stop-signal or emotion recognition performance. Aggression was predicted by both alexithymia and impulsivity, but not by the performance measures. Post hoc analyses shows that alexithymia moderates the relationship between impulsivity and aggression. These results imply that aggressive incarcerated individuals showing impulsive behavior should be screened for TBI, since TBI is often overlooked or misdiagnosed, and indicate that both impulsivity and alexithymia are potential focus points for aggression reduction treatment in TBI patients.

0894 Impulsivity across early stages of synucleinopathy: from high-risk relatives, REM sleep behavior disorder to Parkinson’s disease

Abstract Introduction Increased impulsivity is a common neuropsychiatric feature in patients with Parkinson’s disease (PD), especially attributed to the use of dopaminergic medications. Interestingly, emerging evidence suggested that impulsivity had changed in drug-naïve PD patients. However, it remains unclear whether impulsivity has been altered in prodromal stage of PD, namely isolated rapid eye movement sleep behavior disorder (iRBD) and their high-risk relatives. Methods This was a cross-sectional study with four groups of subjects, including early drug-naive PD patients, patients with iRBD and their first-degree relatives (iRBD-FDRs, a high-risk group with potential prodromal RBD features), and controls. A panel of neuropsychological computerized tasks, including go/no-go task, four-choice serial reaction time task (4CSRTT), beads task, balloon analogue risk task (BART) and delay/effort discounting task, would measure various dimensions of motor and decisional impulsivity. Results A total of 331 subjects were recruited, including 27 early drug-naïve PD patients (mean age ± SD: 70.1 ± 5.8 years, 77.8% man), 152 iRBD patients (67.2 ± 6.6 years, 77.6% man), 68 iRBD-FDRs (63.2 ± 6.4 years, 51.5% man), and 84 controls (67.4 ± 8.1years, 61.9% man). Early drug-naïve PD and iRBD patients had fewer numbers of extracted beads in beads task 1 (P&amp;lt; 0.001) and task 2 (P&amp;lt; 0.001) in making decisions and fewer numbers of pumps of unexploded blue balloons in BART (P&amp;lt; 0.001) than controls and iRBD-FDRs, suggesting a higher level of reflection impulsivity and a lower level of risk taking, respectively. In addition, early drug-naïve PD and iRBD patients had more no-go errors in go/no-go task (P=0.023), suggesting a marginally lower level of response inhibition in PD and iRBD groups. Early drug-naïve PD and iRBD patients had more premature responses in 4CSRTT than iRBD-FDRs (P=0.008). The delay and effort discounting indexes were comparable among four groups. Conclusion While risk taking and response inhibition decreased, reflection impulsivity actually increased in iRBD and drug-naïve PD patients. These novel findings indicated that a complex construct of altered impulsivity has already occurred at the earlier stage (at iRBD) of α-synucleinopathy, which will have implications for pathophysiology and clinical management. Support (if any) This study has been supported by the General Research Fund (14116119).

Concurrent measures of impulsive action and choice are partially related and differentially modulated by dopamine D1- and D2-like receptors in a rat model of impulsivity

Impulsivity is a multidimensional construct, but the relationships between its constructs and their respective underlying dopaminergic underpinnings in the general population remain unclear. A cohort of Roman high- (RHA) and low- (RLA) avoidance rats were tested for impulsive action and risky decision-making in the rat gambling task, and then for delay discounting in the delay-discounting task to concurrently measure the relationships among the three constructs of impulsivity using a within-subject design. Then, we evaluated the effects of dopaminergic drugs on the three constructs of impulsivity, considering innate differences in impulsive behaviors at baseline. Risky decision-making and delay-discounting were positively correlated, indicating that both constructs of impulsive choice are related. Impulsive action positively correlated with risky decision-making but not with delay discounting, suggesting partial overlap between impulsive action and impulsive choice. RHAs showed a more impulsive phenotype in the three constructs of impulsivity compared to RLAs, demonstrating the comorbid nature of impulsivity in a population of rats. Amphetamine increased impulsive action and had no effect on risky decision-making regardless of baseline levels of impulsivity, but it decreased delay discounting only in high impulsive RHAs. In contrast, while D1R and D3R agonism as well as D2/3R partial agonism decreased impulsive action regardless of baseline levels of impulsivity, D2/3R agonism decreased impulsive action exclusively in high impulsive RHAs. Irrespective of baseline levels of impulsivity, risky decision-making was increased by D1R and D2/3R agonism but not by D3R agonism or D2/3R partial agonism. Finally, while D1R and D3R agonism, D2/3R partial agonism and D2R blockade increased delay discounting irrespective of baseline levels of impulsivity, D2/3R agonism decreased it in low impulsive RLAs only. These findings indicate that the acute effects of dopamine drugs were partially overlapping across dimensions of impulsivity, and that only D2/3R agonism showed baseline-dependent effects on impulsive action and impulsive choice.

Functional and pharmacological role of the dopamine D4 receptor and its polymorphic variants.

The functional and pharmacological significance of the dopamine D4 receptor (D4R) has remained the least well understood of all the dopamine receptor subtypes. Even more enigmatic has been the role of the very prevalent human DRD4 gene polymorphisms in the region that encodes the third intracellular loop of the receptor. The most common polymorphisms encode a D4R with 4 or 7 repeats of a proline-rich sequence of 16 amino acids (D4.4R and D4.7R). DRD4 polymorphisms have been associated with individual differences linked to impulse control-related neuropsychiatric disorders, with the most consistent associations established between the gene encoding D4.7R and attention-deficit hyperactivity disorder (ADHD) and substance use disorders. The function of D4R and its polymorphic variants is being revealed by addressing the role of receptor heteromerization and the relatively avidity of norepinephrine for D4R. We review the evidence conveying a significant and differential role of D4.4R and D4.7R in the dopaminergic and noradrenergic modulation of the frontal cortico-striatal pyramidal neuron, with implications for the moderation of constructs of impulsivity as personality traits. This differential role depends on their ability to confer different properties to adrenergic α2A receptor (α2AR)-D4R heteromers and dopamine D2 receptor (D2R)-D4R heteromers, preferentially localized in the perisomatic region of the frontal cortical pyramidal neuron and its striatal terminals, respectively. We also review the evidence to support the D4R as a therapeutic target for ADHD and other impulse-control disorders, as well as for restless legs syndrome.

The impulsive behavior short scale-8 (I-8): A comprehensive validation of the English-language adaptation.

The Impulsive Behavior Short Scale–8 (I-8) measures the psychological construct of impulsivity with four subscales comprising two items each (completion time < 1 min). The aim of the present study was threefold: (1) to assess the psychometric properties (objectivity, reliability, and validity) of the English-language I-8; (2) to compare these psychometric properties with those of the original German-language source version of the scale; and (3) to test the cross-national comparability of the scale via measurement invariance tests. For this purpose, we used heterogeneous quota samples from the UK and Germany. Our results indicate that I-8 is a reliable and valid short scale with highly comparable psychometric properties across both language versions. In addition, I-8 showed a highly similar correlational pattern with various extraneous variables across the two nations. Furthermore, partial scalar invariance and full invariance of residual variances held, allowing the comparison of latent means and observed (co)variances across nations. I-8 lends itself as a measure of impulsive behavior especially in surveys in which assessment time is limited, such as in large-scale cross-national surveys.

The Effect of Impulsivity on Addition and Addictive Tendencies: A Meta-analysis

Background: Immature behaviors, including impulsivity and lack of control lead to personal and social pathologies, such as addiction. Methods: This meta-analysis study aimed to evaluate the effect of impulsivity on addition and addictive tendencies. This comprehensive interdisciplinary quantitative meta-analysis integrated the research findings regarding the effect of impulsivity on addiction and addictive tendencies based on secondary data. A checklist was developed for collecting data based on the article title, author specifications, publication year, setting, research type, hypothesis, data collection instrument, statistical population, sample size, significance level, and probability value to avoid bias in the study selection protocol. Results: The results of studies were divided into nine databases to calculate the effect size, and finally, 11 studies were analyzed. The descriptive data analysis and effect size calculation were performed in the Comprehensive Meta-Analysis Software (CMA) version 2.0. Based on the fixed-effects model, 0.153 of the studies contributed significantly to the actual fixed effect sizes. The difference in effect sizes was due to sampling error. The random-effects model (0.202) suggested the independence of the studies (P &lt; 0.001) with moderate robustness. Conclusions: According to the results, the behavioral construct of impulsivity significantly and positively affected addictive behaviors and tendencies. Therefore, the mediating effect of impulsivity, promote resilience, and train protective strategies for individuals prone to addiction should be controlled to improve mental health quality and develop social, communication, and life skills.

0260 Does multi-dimensional impulsivity mediate the relationship between poor sleep health and depressive symptoms in late adolescents?

Abstract Introduction Abundant evidence links poor sleep health to problems with mental health, including depression. Poor sleep is also associated with deficits in impulse control, which have been linked in turn to depressive symptoms, perhaps most notably suicidality. However, whether impulsivity may partly account for the relationship between poor sleep health and depressive symptoms remains understudied. Here, we examined whether multi-dimensional impulsivity mediated the relationship between sleep health and depressive severity in a sample of late adolescent drinkers. Methods The sample consisted of 96 late adolescents (58.3% female; mean age 17.6 years) reporting regular alcohol use. Daily sleep duration, timing (sleep midpoint), and continuity (efficiency) were assessed using wrist actigraphy. Five facets of impulsivity (namely, negative urgency, lack of perseverance, positive urgency, lack of premeditation, and sensation seeking) were assessed via the UPPS-P Impulsive Behavior scale. Depressive symptoms were assessed via the Inventory of Depressive Symptomatology (IDS-SR-30). Results Mediation analyses showed that the associations between sleep health and depression severity were not mediated through impulsivity. However, results indicated that negative urgency and lack of perseverance were associated with increased severity in depression (B = .75, 95% CI, .27, 1.23 for negative urgency; B = .55, 95% CI, .12, .97 for lack of perseverance), whereas lack of premeditation was inversely associated with depression severity (B = -.72, 95% CI, -1.15, -.29). Conclusion Our findings suggest that sleep duration, timing and continuity were not related to any of the multi-dimensional impulsivity components used. However, findings show that negative urgency and lack of perseverance were related to heightened depressive severity but lack of premeditation was known to decrease depression severity. Further analysis may be needed to examine the mediational paths in the associations between sleep health and depressive symptoms, for example, by using latent constructs of sleep health and impulsivity, thus taking measurement errors into account. Support (If Any) This research was funded by R01 AA026249 (Hasler) by the National Institute of Alcohol Abuse and Alcoholism; and Sleep Research Society Mentor Mentee Award (Kwon).

Validity and Reliability of a Revised S-UPPS-P Impulsive Behavior Scale: The Interplay between Impulsivity and Working Memory

Impulsivity is a multidimensional construct. The UPPS-P model of impulsivity differentiates five distinct dimensions: negative urgency, positive urgency, lack of premeditation, lack of perseverance, and sensation seeking. The present study, reports the first translation and validation of the recently revised short form of the UPPS-P scale (S-UPPS-P) on a Persian-speaking sample, examining the relationship between impulsivity and working memory. who also completed the Positive and Negative Affect Scale (PANAS), the Buss and Perry Aggression Questionnaire, the Behavioral Inhibition and Activation Scales (BIS/BAS), and the Wechsler Digit Span Task (WDST). A series of confirmatory factor analyses, and Cronbach’s alpha results supported the factor structure of the scale. The findings supported the S-UPPS-P model’s hypothesized correlations with PANAS, aggressiveness, and the construct validity of the model. The results of hierarchical regression analysis showed that backward and forward digit span scores of the WDST predicted the S-UPPS-P impulsivity scores over the portion explained by BIS/BAS, PANAS, and aggression scores. To conclude, the revised S-UPPS-P Impulsive Behavior Scale was well supported even in a very different population than usually sampled, adding to growing evidence that it assesses distinct but interrelated aspects of the impulsivity construct. Our findings also suggest that attentional capacities and working memory play important roles in the prediction of impulsivity.

Family Conflict and the Use of Conventional and Electronic Cigarettes in Adolescence: the Role of Impulsivity Traits

Adolescents’ use of tobacco is a worldwide problem due to the negative consequences on their physical and psychosocial development. One contextual variable related to tobacco use is family conflict. Previous research has suggested that the relationship between family conflict and tobacco use could be mediated by personality traits. The aim of this study is to examine the direct and indirect effects of family conflict on tobacco use (conventional and electronic cigarettes) through specific impulsivity constructs. The sample comprised 879 adolescents (56.4% male; M(SD)age = 14.25 (1.88) years). Multiple mediational analysis showed that there was no significant direct effect between family conflict and tobacco use; however, an indirect effect was found between family conflict and conventional cigarette use through sensation seeking and premeditation. With electronic cigarettes, a significant indirect effect was found via sensation seeking. These findings have implications in terms of prevention and treatment of tobacco use during adolescence.

Impulsivity and Metacognition in a Psychiatric Population.

ObjectiveThe main purpose of this study was to examine a possible relationship among the three constructs of impulsivity, according to Barratt’s theory and metacognition subdimensions, as described in Wells and Cartwright–Hatton’s theory, in various psychiatric disorders, in order to explore the potential predictive role of impulsivity on metacognition.MethodThe Barratt Impulsiveness Scale-11 (BIS-11) and the Metacognitions Questionnaire (MCQ-30) were administered to a sample of 100 patients affected by psychiatric disorders. Linear regression was used first to study the relationship between impulsivity as an independent variable and metacognition as a dependent variable and then to evaluate the relationship between the three construct of impulsivity and the five subdimensions of metacognition.ResultsBIS-11 total score was a valid predictor of Total MCQ-30 (p <.0001), whereas Attentive Impulsiveness was a good predictor of the factors “Negative Beliefs” (p <.0001), “Cognitive Confidence” (p =.004) and “Need to control thoughts” (p =.002).Conclusionssince “Attentive Impulsiveness”, “Negative believes”, “Cognitive Confidence” and “Need to Control Thought” are psychological constructs, psychotherapy is the more effective tool to intervene on their imbalance. In particular, literature demonstrates the effectiveness of Cognitive-Behavioural Therapy and Mindfulness therapies in rebalancing impulsivity and enhancing metacognitive skills.

Associations between impulsivity and self-care adherence in individuals diagnosed with Type 2 or prediabetes.

Diabetes is a chronic disease requiring extensive self-care. Different impulsivity constructs, including choice-based and self-report personality measures are associated with decreasing diabetes self-care adherence. However, both choice-based and self-report impulsivity have never been measured for individuals diagnosed with either Type 2 or prediabetes in the same study. The current study examined the relationship between impulsivity and diabetes self-care in 101 adults diagnosed with either Type 2 or prediabetes. Results indicated that increasing self-reported impulsiveness was significantly correlated with decreasing Type 2 diabetic self-care, whereas the choice-based measure was not associated with any self-care measure. No association between impulsivity and self-care was significant for individuals diagnosed with prediabetes. Path analyses showed that self-reported impulsiveness directly and positively predicted problems controlling blood sugar levels in individuals diagnosed with either prediabetes or Type 2 diabetes. However, self-reported impulsiveness only indirectly and negatively predicted exercise and diet adherence via diabetes management self-efficacy for individuals diagnosed with Type 2 diabetes. These results show what specific impulsivity constructs and diabetes management self-efficacy may be incorporated into interventions for increasing specific self-care behaviors.

A Developmental Perspective on Facets of Impulsivity and Brain Activity Correlates From Adolescence to Adulthood

BackgroundOn a theoretical level, impulsivity represents a multidimensional construct associated with acting without foresight, inefficient inhibitory response control, and alterations in reward processing. On an empirical level, relationships and changes in associations between different measures of impulsivity from adolescence into young adulthood and their relation to neural activity during inhibitory control and reward anticipation have not been fully understood. MethodsWe used data from IMAGEN, a longitudinal multicenter, population-based cohort study in which 2034 healthy adolescents were investigated at age 14, and 1383 were reassessed as young adults at age 19. We measured the construct of trait impulsivity using self-report questionnaires and neurocognitive indices of decisional impulsivity. With functional magnetic resonance imaging, we assessed brain activity during inhibition error processing using the stop signal task and during reward anticipation in the monetary incentive delay task. Correlations were analyzed, and mixed-effect models were fitted to explore developmental and predictive effects. ResultsAll self-report and neurocognitive measures of impulsivity proved to be correlated during adolescence and young adulthood. Further, pre-supplementary motor area and inferior frontal gyrus activity during inhibition error processing was associated with trait impulsivity in adolescence, whereas in young adulthood, a trend-level association with reward anticipation activity in the ventral striatum was found. For adult delay discounting, a trend-level predictive effect of adolescent neural activity during inhibition error processing emerged. ConclusionsOur findings help to inform theories of impulsivity about the development of its multidimensional nature and associated brain activity patterns and highlight the need for taking functional brain development into account when evaluating neuromarker candidates.

A impulsividade afeta a tomada de decisão em compras on-line?

Impulsivity can be defined as a comprehensive construct that encompasses characteristics such as action without prior conscious judgment, action with less prudence, risk taking and quick decision. It is a complex phenomenon and can be characterized as a set of cognitive and behavioral patterns that lead to short, medium and long-term losses and can be presented in four distinct constructs, namely: urgency; lack of forethought; lack of persistence and sensation-seeking. With the advancement of technology and access to virtual environments, companies are developing tools to engage consumers and create behavioral strategies that influence decision-making at the time of purchase. The research focuses on understanding how impulsiveness is related to decision making regarding consumption. The objective is to analyze the correlations between individuals with the highest impulsivity score and the number of online purchases according to the four impulsivity constructs, to verify how the low or high price of goods affects the volume of online purchases and whether gender and socioeconomic characteristics interfere in the consumption/impulsivity relationship. The research is cross-sectional, exploratory, consisting of the investigation and analysis of data collected with a sample of 500 participants, neurotypical in the age group of 18-59 years. It will be carried out via an online platform, the following instruments will be used: Impulsive Behavior Scale (UPPS-P), Social Desirability Scale; Socioeconomic Questionnaire; Self-Report Inventory for Adults - 18/59 years old (ASR - 18/59 years old); and the Consumption Questionnaire that will be prepared for this research and then submitted to 6 expert judges with a degree of agreement of ≥80%, to verify: accuracy, sensitivity and specificity in measuring the behavior of compulsive consumption compared to questions of impulsivity and the relationships between sex and income characteristics in impulsive consumption behaviors.

Exposure to Violence Variety as a Risk Factor for Cigarette Smoking: Relevance of Sensation-Seeking and Impulsivity as Mediators

Background Prior research has indicated that exposure to violence is a risk factor associated with cigarette smoking. However, the relevance of variety of exposure for predicting this outcome has remained underexplored. This is problematic, as increased variety of exposure may represent a measure of severity of trauma exposure with less recall bias than other measures. Further, related constructs of sensation-seeking and impulsivity have yet to be investigated as mediators of this relationship. It is predicted that increased variety of exposure to violence results in dysfunctional variation in these constructs, leading to increased daily cigarette use. Methods The present study utilizes data from the first three waves of the Pathways to Desistance study to examine these relationships. Generalized structural equation modeling is used to identify direct and indirect effects of interest. A bootstrap resampling process was used to compute normalized standard errors so that indirect effects were not biased. Results Results indicated that lifetime exposure to violence variety prior to baseline predicted increased daily cigarette use at follow-up. Neither sensation-seeking nor impulsivity were significant mediators when both constructs were included in the model, but impulsivity emerged as a significant mediator when separate mediation models were estimated for each construct. Conclusions The findings indicate the potential utility of screening for variety of exposure to violence to determine adolescents who may be at-risk for high frequency cigarette smoking. Programming focused on impulsivity may play a role in addressing cigarette smoking issues stemming from exposure to violence.

English

BACKGROUND Alcohol use disorder is one of the dangerous public health burden. The construct of impulsivity and its various dimensions in relation with aggression are relevant for understanding alcohol dependence and relapse. The goal of the study is to describe the role of impulsivity and aggression in the context of alcohol dependence. The purpose and implications of this study was to understand the human factors contributing to aggression and impulsivity and in providing advanced treatment programs. METHODS This cross-sectional study was discussed in detail and approved by the ethical committee of the Madras Medical College. The cases were selected consecutively from all the patients attending the outpatients as well as inpatient for the same after fulfilling the inclusion and exclusion criteria, within seven days of last intake of alcohol. The diagnosis was made according to International Classification of Diseases (ICD-10) criteria after ruling out psychotic disorder and other comorbid medical illnesses. Informed consent was obtained from all the patients and caregivers. Descriptive statistics used meticulously to measure the magnitude. RESULTS This study found significant positive correlation (P &lt; 0.001) between impulsivity, aggression subtypes with alcohol dependence. Various subsets in Barrett impulsivity scale (BIS) and subsets of Buss Perry aggression scales (BPAS) had positive correlations. We found that as severity of dependence increases, impulsivity and aggression scores increases and vice versa. The comparison of means of illness variables within groups showed that there was no significant difference between groups in terms of age of onset of illness, last alcohol intake, number of hospital admissions, duration of abstinence and frequency of relapse. CONCLUSIONS This study describes the important role of behavioural model and disease model of alcoholism, 1,2 greatly stresses the inability to control the quantity and frequency of the drinking behaviour. There is higher level of connectivity between alcohol dependence with biological and behavioural indicators of impulsivity and aggression. 3 It supports that relapse is an acquired behaviour in which the individual is able to control his substance taking pattern through adequate cognitive behavioural techniques in addition to pharmacological treatment and also suggest more research needed in future to focus on causality and intervention. KEY WORDS Impulsivity, Aggression, Alcohol dependence, Relapse

Compulsivity and impulsivity in opioid dependence

ObjectiveChronic exposure to illicit opioid drugs can cause serious health and social problems. However, less is known about the differential effect of various opioid treatments, such as methadone and buprenorphine, on neurocognitive domains such as compulsivity and impulsivity, despite their relevance to the treatment of opioid dependence. MethodsA total of 186 participants were recruited with a cross-sectional design: i) illicit heroin users (n = 27), ii) former heroin users stabilized on methadone MMT (n = 48), iii) a buprenorphine maintenance treatment (BMT) group (n = 18), iv) an abstinent (ABS) group with a history of opioid dependence who were previously stabilized on MMT or BMT (n = 29) and v) healthy controls (HC) (n = 64). We used the Intra-Extra Dimensional Shift (IED) and Cambridge Gambling Task (CGT) paradigms for measuring compulsivity and impulsivity constructs respectively. ResultsHeightened compulsivity persisted in the heroin, buprenorphine and abstinent groups. Heroin, methadone and buprenorphine groups exhibited impaired behavioral responses to feedback, consisting of increased deliberation time and poorer risk adjustment. Higher compulsivity measures were negatively associated with opioid dose which may reflect sedation effects. ConclusionsOur results suggest that compulsivity and impulsivity are core neurocognitive dimensions for opioid dependence which differ in their presentation according to the stage of treatment. Participants taking higher morphine equivalent doses performed better in compulsivity measures. These findings have implications for the treatment of opioid dependence and longitudinal studies are warranted.