Consolidation Status Research Articles

Powder wetting behavior and granule formation mechanism expansion in single-drop granulation

Single-drop granulation is performed under a variety of conditions to characterize the behavior that results from a liquid droplet impacting a powder bed. Drop impact velocity, liquid binder properties, powder bed consolidation status, and primary particle size are all demonstrated to have significant effects on the resulting granule formation mechanism. The process is broken down into a drop impact/drop deformation stage, a drop rebound stage, and a drop imbibition stage. These stages are often in competition with each other to determine the overall drop penetration behavior. Twelve granule formation mechanisms are identified and characterized in this study, in addition to two established granule formation mechanisms that were not observed in this work.

An energy-saving loading strategy: cyclic vacuum preloading treatment of soft ground

Vacuum preloading is a commonly adopted method for improving soft ground. During the preloading period, the applied vacuum pressure is constant or multistaged, implying that the vacuum pump must work continuously with constant or increasing operating power. To reduce the energy consumption of the vacuum pump, a new loading strategy of cyclic vacuum loading was proposed in this study, whereby the pump is periodically switched on and off, and hence the vacuum pressure ascends and descends accordingly. To guide the design of cyclic vacuum preloading, a large-strain radial consolidation theory incorporating the shifting of the consolidation status of ground soil from normally consolidated to overconsolidated (and vice versa) was established in the present study. Based on the established theory, the treatment effects of cyclic vacuum loading can be quantitatively determined, including the ground settlement and the degree of consolidation, while the energy consumption can be simply determined by multiplying the power by the operating time of the vacuum pump, which works only during the ascending stage of cyclic vacuum pressure. Two cases of the cyclic vacuum preloading strategy were evaluated herein, that is, the complete cyclic vacuum loading and combined cyclic/constant vacuum loading cases. Finally, experimental tests were conducted to demonstrate the energy-saving effect of cyclic vacuum preloading. Compared to the conventional vacuum preloading strategy (i.e., constant vacuum pressure), the energy consumption of the cyclic vacuum loading strategy can be drastically reduced (80% reduction), while the treatment effects remain basically unaffected.

Mapping the Evolution of Media Management and Industry Studies in Journalism & Mass Communication Quarterly: 100-Year Retrospective and Future Directions

To draw a picture of the evolution of media management research in the context of published scholarly work, this invited piece reviews works related to media management and industry studies published in JMCQ for the past 100 years. Initially, attention was paid to understanding the basics of newspaper as an economic entity. Since then, the status of chain ownership and consolidation, impacts of consolidation on newspaper content, intermedia competition, human resource management, business strategy, adoption/consumption, engagement, and recently, AI in the media industry were the major topics in the media management studies chronologically. Future directions for media management and industry studies were discussed.

Evaluation of the consolidation status of heavy oil sands through rock physics analysis: A case study from Fengcheng oilfield

Heavy oil is an important unconventional oil resource with huge availability worldwide, which also forms the primary oil source in Fengcheng oilfield, XinJiang, China. The elastic properties and consolidation status of heavy oil sands are of significant values as they can provide guidance for reservoir exploration and production. However, due to the lack of detailed rock physics investigation of the heavy oil sands in Fengcheng oilfield, the knowledge about their micro-scale elastic properties and consolidation status is still limited. Based on the well log data and laboratory measurements, we performed rock physics analysis of the heavy oil sands’ elastic properties. We first analyzed the well logs to determine the oil sands formations and then quantitatively delineated the relations between density, porosity, and velocity. Combining with laboratory measured data, we applied theoretical rock physics models to characterize the consolidation status of the heavy oil sands. Our results show that the oil sands in this area are poorly consolidated with a loose rock frame. Overall, this study highlights the micro-scale elastic properties of the heavy oil sands in Fengcheng oilfield and also reveals the consolidation status. It presents a method of integrating well log, laboratory data, and rock physics analysis to evaluate the consolidation status of heavy oil sands, which can facilitate the future detailed petrophysical analysis and provide important information for seismic characterization and drilling risk evaluation.

Impact of Double Expression of MYC and BCL-2 on Outcomes in Primary CNS Lymphoma: A UK Multicentre Analysis

Introduction Primary central nervous system lymphoma (PCNSL) is a rare B cell lymphoma with an aggressive course. Relapses remain common even with intensive immuno-chemotherapy treatment options such as MATRix and consolidation with autologous stem cell transplant (ASCT), and prognostic tools are limited. Although, double expressor status (co-expression of both MYC and BCL-2) is well established in systemic de novo DLBCL, its prognostic impact in PCNSL has been understudied. Here we evaluated the prognostic value of BCL-2, BCL-6, and MYC expression in a retrospective cohort of treated PCNSL patients diagnosed at 7 academic centres in the UK. Methods We performed this retrospective analysis on histologically-confirmed PCNSL patients diagnosed consecutively between 1st May 2015 and 31st May 2020. Treatment with a high-dose methotrexate-based chemotherapy regimen was a mandatory inclusion criterion. BCL-2 and MYC immunohistochemistry (IHC) protein expression data were collated from local diagnostic histology reports and double expressor (DE) status was defined as per WHO criteria (MYC: surface expression > 40% of cells and BCL-2: >50% of cells). Outcomes included response rates, progression-free survival (PFS) and overall survival (OS). Where available, diagnostic fluorescence in situ hybridisation (FISH) data was collected for BCL-2, BCL-6 and MYC loci translocations. Cox-regression for PFS and OS were used to determine baseline predictors of response and survival and to construct multivariable models for factors associated with outcome. Results In total, 242 patients were analysed. Key baseline patient characteristics and IHC data are summarised in Table 1. Median age was 65 years (IQR 56-71), 60% were male and 64% of patients had an ECOG performance status (PS) of 0-1. One hundred and seventy-four (72%) patients received treatment with MATRix chemotherapy; these patients were younger (median age 62 vs. 73 years, p< 0.01), had better baseline PS (PS ≤ 1: 75% vs. 37%, p< 0.01) and higher rates of consolidation with BCNU-thiotepa ASCT (58% vs. 7%, p< 0.01). Double expressor (DE) status was assessable in 169/242 (69%) patients. Reasons for absent DE status were missing IHC expression data (BCL-2: n=28; MYC: n=44) or IHC expression data not reported in line with WHO recommended criteria (BCL-2: n=45; MYC: n=7). In the DE-assessable cohort (n = 169 patients), 40% of patients had DE PCNSL, higher than estimates of DE prevalence in systemic DLBCL (reported rates between 20 and 30%). As only 40 cases (17%) underwent FISH assessment for concurrent MYC and BCL-2 loci translocation (double hit status), correlation between double hit and DE status was not possible. DE status was not associated with patient age at diagnosis, baseline PS or treatment received. With a median follow up of 1.7 years, 34% of patients relapsed and 45% died. Although single MYC or BCL-2 expression alone had no significant association with OS or PFS in the entire cohort, DE status was associated with significantly poorer PFS, and earlier relapse (median 0.86 years vs. 2.77 years; HR 1.61 (1.07 - 2.41); p=0.021) (Fig. 1). In a subgroup analysis restricted to patients treated with MATRix chemotherapy (n = 116 patients), there was a trend towards inferior PFS and OS, although this did not reach significance in a univariable analysis. However, the adverse prognostic impact of DE status on PFS was maintained in a multivariable analysis modelling age, baseline PS, treatment received, ASCT consolidation status and DE status both for the entire cohort (HR 1.75 (1.15 - 2.66); p<0.01) and the MATRix treated subgroup (HR 1.91 (1.08 - 3.36); p=0.03). A trend towards an association between DE status and OS was noted but did not reach significance in either a univariable or multivariable analysis. We observed no significant difference in PFS or OS between DE-PCNSL and non-DE-PCNSL patients who received MATRix and consolidation with ASCT, perhaps indicating that the adverse impact of DE status is modified by this treatment strategy, although the sample size was small (n=66). Conclusions In a large, retrospective cohort of PCNSL patients treated at 7 UK academic treatment centres, double expression of MYC and BCL-2 by IHC was associated with inferior PFS even in patients treated with MATRix chemotherapy. Validation of this finding in independent cohorts is warranted. ___ JO, CPF and KC share senior authorship Figure 1View largeDownload PPTFigure 1View largeDownload PPT Close modal

THE FUNDAMENT OF CITIZENSHIP: CONTRACT OR STATUS?

This article aims to analyze the fundament of citizenship in the field of social construction of the subjects and their relations about the critical-reflective for the formative status of the subjects, theories in the field of citizenship and their perceptions in favor of a structural contract or consolidated status to the subjects. The methodology applied to the theme permeates the bibliographic research of qualitative nature, justifying the discussion proposed for the formation process of the subjects for the collectivity.

Hematological and immunological responses to naturally occurring bovine respiratory disease in newly received beef calves in a commercial stocker farm.

The objective was to determine temporal changes in hematological and immune parameters in response to naturally occurring bovine respiratory disease (BRD) in commercially managed stocker calves. Forty newly weaned beef steers purchased from auction markets were housed at a commercial stocker operation in Crossville, TN. Blood samples, rectal temperature, and thoracic ultrasonography (TUS; 1: normal to 3: severe) were collected on days 0, 7, 14, and 21. Castration status (FC: freshly castrated; PC: previously castrated) was determined on arrival based on presence of a fresh castration site at the scrotum. Calves received antibiotics for BRD based on clinical severity scoring (CSS; 0: moribund, 4: moribund) and rectal temperature. Complete blood counts (CBC) were performed. Calves were categorized based on the number of treatments (NumTrt) received (0x, 1x, and 2x). Temporal variations in CBC and immune parameters were analyzed using mixed model repeated measure ANOVA (Proc GLIMMIX; SAS 9.4). Variation of CBCs and immune parameters based on TUS was determined using mixed model ANOVA. There was a NumTrt by day interaction effect on the responses of white blood cells (WBC) (P = 0.04) and haptoglobin (HPT) (P = 0.04). On day 21, WBC were greater in the 2x NumTrt group than other groups, but there were no differences in WBC between NumTrt levels on other days. Haptoglobin was greater in the 2x group on days 14 and 21 than 0x or 1x. Red blood cells (RBC) (P = 0.02) and WBC (P = 0.04) differed between FC and PC groups, and lower RBC and WBC were observed in the FC group. A castration status × day effect for mean corpuscular volume (MCV; P = 0.04) was observed where FC group had higher MCV at days 14 and 21 than the PC group. Tumor necrosis factor-α differed based on NumTrt (P = 0.03) and higher concentrations were found in 2x group. We observed a day effect for IL-1β (P = 0.009) and TNF-α (P = 0.001). Significant effect of TUS on HPT at day 14 (P = 0.0004) and day 21 (P = 0.002) was observed. Combining HPT and platelet explained 15% of the variability in treatment status on a given day, whereas HPT and hemoglobin explained 10% of the variability in lung consolidation status. Although hematological and immunological parameters varied largely in our study, the potential of combining HPT with hematological variables should be studied further. Results from this study would help in understanding temporal changes in CBC and immune parameters in newly received stocker cattle.

Direct Neural Evidence for the Contrastive Roles of the Complementary Learning Systems in Adult Acquisition of Native Vocabulary.

The Complementary Learning Systems (CLS) theory provides a powerful framework for considering the acquisition, consolidation, and generalization of new knowledge. We tested this proposed neural division of labor in adults through an investigation of the consolidation and long-term retention of newly learned native vocabulary with post-learning functional neuroimaging. Newly learned items were compared with two conditions: 1) previously known items to highlight the similarities and differences with established vocabulary and 2) unknown/untrained items to provide a control for non-specific perceptual and motor speech output. Consistent with the CLS, retrieval of newly learned items was supported by a combination of regions associated with episodic memory (including left hippocampus) and the language-semantic areas that support established vocabulary (left inferior frontal gyrus and left anterior temporal lobe). Furthermore, there was a shifting division of labor across these two networks in line with the items’ consolidation status; faster naming was associated with more activation of language-semantic areas and lesser activation of episodic memory regions. Hippocampal activity during naming predicted more than half the variation in naming retention 6 months later.

Stability of the foundation trench of the immersed tunnel subjected to combined wave and current loading

The determination of stability for the submarine artificial slope is important in the construction of offshore structures such as immersed tunnels and embedded pipelines. Aimed at this issue, a two-dimensional (2D) integrated model is proposed to investigate the slope stability of the foundation trench for the immersed tunnel under the combined wave and current loading, as in the real marine environment. The Reynolds-Averaged Navier-Stokes (RANS) equations are solved to simulate the wave field, meanwhile the current is realized by setting boundary inlet and outlet velocity at both sides. The interface between water and air is tracked by conservative Level Set Method (LSM). The wave-current induced pore pressure in seabed is calculated by Darcy's law, and the shear strength reduction method is adopted to judge the damage of the elastic-plastic seabed slope which is described through Mohr-Coulomb constitutive model. The wave-current model is validated through comparing with experimental data and analytical solution. The consolidation status of foundation trench after excavation is obtained and set as the initial condition for analysis. The factor of stability (FOS) for the slope is demonstrated to depend on the relative distance between wave crest and slope. The minimum of FOS corresponding to the most dangerous situation is regarded as the stability index for the slope with specific slope ratio in the whole process of dynamic wave-current loading. Through the parametric analysis based on this new evaluation method, the effects of soil strength parameters, slope ratio and current direction on the slope stability are discussed in detail.

Finite Element Study on Calculation of Nonlinear Soil Consolidation Using Compression and Recompression Indexes

The coefficient of consolidation is traditionally considered as a constant value in soil consolidation calculations. This paper uses compression and recompression indexes to calculate the solution-dependent nonlinear compressibility, thus overconsolidation and normal consolidation are separated during the calculations. Moreover, the complex nonlinear consolidation can be described using the nonlinear compressibility and a nonlinear permeability. Then, the finite element discrete equation with consideration of the time-dependent load is derived, and a corresponding program is developed. Subsequently, a case history is conducted for verifying the proposed method and the program. The results show that the method is sufficiently accurate, indicating the necessity of considering nonlinearity for consolidation calculations. Finally, three cases are compared to reveal the importance of separating the overconsolidation and normal consolidation. Overall, this study concluded that it is inadequate to consider just one consolidation status in calculations, and that the proposed method is more reasonable for guiding construction.

Monitoring urban land surface deformation (2004–2010) from InSAR, groundwater and levelling data: A case study of Changzhou city, China

Land deformation caused by the overexploitation of groundwater has become a potential geological hazard in Changzhou, China. To reduce the potential damage from deformation disasters, it is quite necessary to monitor them. In this study, C-band ENVISAT ASAR synthetic aperture radar (SAR) datasets acquired from 2004 to 2010 were processed with the small baseline subset (SBAS) interferometric SAR (InSAR) method to investigate the spatial–temporal distribution of land deformation. Levelling survey data were used to assess the deformation accuracy measured by the InSAR method, and groundwater level data were used to analyse the incentives for deformation. The SBAS InSAR results found several subsidence regions in the Wujin district and the central part of the Zhonglou district. The annual deformation rate calculated from the C-band interferograms ranged from −65 to +35 mm/yr in the line of sight (LOS) direction, and the cumulative subsidence ranged from −0.35 to 0.13 m in the vertical direction. The levelling survey data show that the two measurements are generally consistent. Correlation analysis between the groundwater table and InSAR measurements at six groundwater well stations shows that groundwater recharges can cause land rebound within the Changzhou urban region. However, subsidence was also observed simultaneously with a rising water table, which might have been caused by the status of consolidation of the strata. Our study provides scientific evidence on the management of groundwater extraction and the assessment of land-subsidence hazard.

Taking interaction seriously: Asymmetrical roles and the behavioral foundations of status

Status has once again become a prominent topic in international relations. However, vague, incomplete, and incompatible definitions continue to stifle the development of a cohesive research program. Even the most sophisticated conceptualizations proposed fail to comprehend the full range of status conflicts and ambitions. Current research centers on collective beliefs about the traits that are valued in individual actors, so it especially fails to properly account for status differentiations that emerge through bilateral interactions and for defiant acts that upend local status hierarchies. It also neglects the most intense status infringements: acts and relationships that are humiliating. To remedy this conceptual weakness, this article will first review conceptual work in International Relations and beyond. It will then present an integrated model of two distinct status hierarchies — prestige and role status — and their causal linkages. In so doing, the article will attempt to clarify how “status” relates to similar concepts, such as “authority,” “prestige,” “honor,” and “glory.” The explanatory value of this consolidated status framework will be demonstrated through a more nuanced and consistent discussion of Russia’s seemingly erratic status disputes with “the West.”

Two-dimensional model of wave-induced response of seabed around permeable submerged breakwater

This article focuses on a two-dimensional numerical model established to determine the seabed dynamic response in the region of a permeable submerged breakwater. The wave motion in this article is governed by the volume-averaged Reynolds-averaged Navier–Stokes equation, whereas Biot’s poro-elastic equation determines the seabed foundation. The water surface is recorded using the volume of fluid technique. In this study, the results for the two-dimensional seabed dynamic response for both the consolidation status and the dynamic wave-induced response status for the seabed foundation coupled with submerged breakwater are illustrated. The numerical results examined from the dynamic pore pressure, the effective stresses, the shear stress, and the seabed soil displacements revealed that the impact of dynamic response at the offshore zone/seaward on the seabed foundation is more developed than at the onshore zone/harbor side. Parametric results analysis as regards the effect of the wave, the seabed, and the submerged breakwater structure variation significantly affected the seabed foundation response coupled with the breakwater structure. The numerical outcome on the liquefaction potential shows that the seabed foundation is more seemingly to liquefy and happen approximately at the toe of the submerged breakwater under the wave loading.

Mosquitoes (Diptera: Culicidae) of Singapore: Updated Checklist and New Records.

Prior to 1965, Singapore was part of the Malaya (now Malaysia) and was usually not mentioned when mosquito records were reported for Malaya. Consequently, many species that occurred in Singapore were not listed in the world mosquito catalog, and the available checklist for Singapore since 1986 is incomplete, with some imprecise species information. In updating this checklist, we examined and verified mosquito specimens collected from Singapore in various depositories, including a thorough review of past taxonomic literature. Here, we report a checklist of 182 mosquito species, 33 new distribution records, and a consolidated status list of vectors for Singapore. As Singapore is a travel hub and hosts one of the busiest container ports in the world, there is a risk of introducing mosquito species and their associated pathogens of human disease to the country. Hence, the distribution records are important to increase our knowledge on mosquito ecology as well as to understand the risk of newly introduced vectors and their associated pathogens.

Do donors respond to discretionary accounting information consolidation?

PurposeThe purpose of this paper is to investigate donor responses to discretionary accounting information consolidation. Nonprofit (NP) financial statement consolidation discretion significantly impacts program ratio reporting, the primary NP performance measure. Stakeholders are misled to allocate limited resources inefficiently. While some NPs file group Internal Revenue Service (IRS) Form 990 returns with their affiliates, effectively providing consolidated statements, others choose to file independently of their affiliates.Design/methodology/approachThe authors use OLS regression analysis and panel data for 5,697 NP-year observations for the period 2009-2011 retrieved from the National Center for Charitable Statistics Form 990 database.FindingsThe authors find evidence that consolidation discretion substantially impacts donor decisions. NP managers have incentive to utilize consolidation discretion to influence charitable giving.Practical implicationsThe authors urge the IRS and the Financial Accounting Standards Board to reconsider the consolidation guidance for NP organizations, to develop performance measures beyond the widely used program ratio, and to require program ratio segment reporting to allow for better comparability among NPs irrespective of consolidation status. Further, the authors caution stakeholders to consider supporting organization transactions in their resource allocation decisions.Originality/valueThe authors are the first to use NP supporting organization information to investigate consolidation discretion and its impact on donor responses.

Concentration of entrepreneurs on the pharmaceutical market: selected issues

Aim:The article has been selected due to the need to determine the legal basis for the consolidation of entrepreneurs on the pharmaceutical market and to identify the difference from the common pattern established by the regulations set forth in the Competition and Consumer Protection Act dated 16 February 2007. The selection of an enactment (the Competition and Consumer Protection Act or the Pharmaceutical Law Act) as the appropriate basis for ruling shapes the legal status of an entrepreneur on the pharmaceutical market, in particular with respect to selecting specific remedies. Design / Research methods:The text of enactments was analyzed using mainly the linguistic method. The aim of the analyzed regulations and the system of values protected by law were also investigated. Conclusions / findings:The regulations concerning anti-competition consolidation on the pharmaceutical market set forth in the Pharmaceutical Law Acta are lex specialis with respect to solutions adopted in the Competition and Consumer Protection Act (this applies only to issuing a permit for running a retail pharmacy and a limited service pharmacy). These regulations are related with respect to content but, simultaneously, they differ with respect to the adopted consolidation criteria (qualitative criterion: the Competition and Consumer Protection Act, and quantitative criterion: the Pharmaceutical Law Act). The regulations set forth in the Competition and Consumer Protection Act apply also to consolidation on the pharmaceutical market since the obligation to report a consolidation intent is not specific to the industry in which the consolidation takes place. It means that President of the Office of Competition and Consumer Protection is competent to study the consolidation status and issue decisions related to consolidation on the pharmaceutical market, and entrepreneurs can appeal from the President’s decisions to the Regional Court in Warsaw. Originality / value of the article:The approach presented is not present in the current literature which is the main value of the article. The subject matter of the article can be interesting for entrepreneurs present on the pharmaceutical market and law practitioners.

Electrochemistry of single molecules and biomolecules, molecular scale nanostructures, and low-dimensional systems

Electrochemistry at ultra-small scales, where even the single molecule or biomolecule can be characterized and manipulated, is on the way to a consolidated status. At the same time, molecular electrochemistry is expanding into other areas of sophisticated nano- and molecular-scale systems including molecular scale metal and semiconductor nanoparticles (NPs) and other nanostructures, e.g. nanotubes, “nanoflowers” etc. The new structures offer both new electronic properties and highly confined novel charge transfer environments.

中山間地域の水稲作経営における農地集積の実態と展望

The purpose of this study was to clarify the current and future status of farmland consolidation for rice paddy field farms, using the case of “canyon-type hilly and mountainous areas.” In the study area, small-sized paddy fields expand across long and narrow areas along mountain streams and straddle many water systems, given the expanded scale of farming. Because of the farmers’ increasing burdens for water management and weeding on the ridges between paddy fields, there is a limit to the scale expansion by debt. On the other hand, if the farmers specialize in the consignment of machine operation, an operation on a scale of 20–30 ha is possible, and high income can be expected. It is desired to organize residents who can weed on the ridge and manage water by utilizing subsidies so that core farmers can specialize in machine operation.

Neither Maximum Tumor Size nor Solid Component Size Is Prognostic in Part-Solid Lung Cancer: Impact of Tumor Size Should Be Applied Exclusively to Solid Lung Cancer

We aimed to investigate the prognostic impact of tumor size based on the consolidation status by thin-section computed tomography. We evaluated 1,181 surgically resected clinical N0 M0 non-small cell lung carcinomas. Consolidation tumor ratio (CTR) was evaluated for all, and tumors were classified into three groups, namely pure ground-glass opacity (CTR= 0; n= 168), part-solid (0 < CTR < 1.0; n= 448), and solid (CTR= 1.0; n= 565). The impact of tumor size was assessed based on CTR using Cox proportional hazards model. Tumor size significantly differentiated the 5-year overall survival (≤20 mm; n= 638: 93.4%; 21-30 mm; n= 284: 84.2%; 31-50 mm; n= 193: 69.3%; ≥51 mm; n= 66: 43.5%; p < 0.0001). When we evaluated the impact of tumor size based on CTR, the 5-year overall survival differed significantly in patients with radiologic solid lung cancer (≤20 mm: 83.0%; 21-30 mm: 75.4%; 31-50 mm: 56.2%; ≥51 mm: 45.3%; p < 0.0001). In contrast, it did not affect the 5-year overall survival in patients with radiologic pure ground-glass opacity (100% regardless of the tumor sizes) and part-solid lung cancer (≤20 mm: 97.7%; 21-30 mm: 94.6%; 31-50 mm: 93.4%; p= 0.1028; 0 < CTR ≤ 0.5: 98.4%; 0.5 < CTR < 1.0: 95.0%; p= 0.1247). Furthermore, maximum tumor size (p= 0.6370), solid component size (p= 0.2340), and CTR (p= 0.1395) were not associated with poor overall survival in radiologic part-solid lung cancer. The impact of maximum tumor size should be applied only to radiologic solid lung cancer without the ground-glass opacity component on thin-section computed tomography. On the other hand, we recommend that pure ground-glass opacity and part-solid lung cancers be described, respectively, as clinical-Tis and clinical-T1a, which are independent of maximum tumor size and solid component size on thin-section computed tomography.

Oncological Characteristics of Radiological Invasive Adenocarcinoma with Additional Ground-Glass Nodules on Initial Thin-Section Computed Tomography: Comparison with Solitary Invasive Adenocarcinoma

IntroductionWe aimed to evaluate the oncological outcomes of radiological invasive adenocarcinoma with additional ground-glass nodules (AGGNs) on initial thin-section computed tomography (CT). MethodsWe examined 473 patients with surgically resected clinical stage IA lung adenocarcinoma showing a radiological invasive appearance on thin-section CT. Radiological invasiveness was defined as a solid tumor with a consolidation tumor ratio of at least 0.5 but no greater than 1.0 on thin-section CT. ResultsNinety patients (19%) had dominant invasive adenocarcinoma (DA) with AGGNs, whereas 383 (81%) had solitary invasive adenocarcinoma (SA). DA showed a significantly lower maximum standardized uptake value of 18F-fluorodeoxyglucose on positron emission tomography (p = 0.0086), higher frequency of radiological part solid tumor (p = 0.0232) and histological lepidic predominant tumor (p = 0.0015), and lesser presence of nodal involvement (p = 0.0350) and lymphovascular invasion (p = 0.0001) than with SA. Surgically resected AGGNs were shown to be pathologically atypical adenomatous hyperplasia in 17% of patients, adenocarcinoma in situ in 53%, and minimally invasive adenocarcinoma in 21%. Furthermore, the 5-year overall survival of DA with AGGNs was better than that of SA, and the difference was significant (92.2% versus 79.9%, p = 0.0323). On the basis of a multivariate analysis, tumor size, maximum standardized uptake value, and consolidation status of DA/SA were significant prognostic factors of survival for all patients (p = 0.0039, 0.0236, and 0.0385, respectively), whereas the presence of AGGNs was not associated with poor overall survival (p = 0.4809). ConclusionDA accompanied by AGGNs showed an oncologically less invasive nature compared with SA. Presence of AGGNs is not related to poor prognosis, and is neither indicative of an advanced stage nor a contraindication to surgical resection in patients with clinical stage IA radiological invasive adenocarcinoma.