Effects Of Iron Deficiency Research Articles

Recent article of nutritional interest to pediatricians

Intestinal Bleeding, Iron Deficiency, and Introduction of Cow’s Milk Bleeding from the intestinal tract in infants fed whole cow’s milk was confirmed in a randomized study of infants at approximately 6 months of age.’ Frank iron deficiency developed in 1 of 52 infants. The serious consequences of iron deficiency warrant care in introducing cow’s milk to the infant diet before other sufficient iron-containing foods are consumed. Milk Allergy For treatment of milk allergy, the consensus has been to use a hydrolyzed protein as the basis of a formula. Recently, at least four cases of anaphylaxis in infants fed protein hydrolysates have been recorded. At first, attention was drawn to children who reacted with distress to partially hydrolyzed formulas. The latest reports, however, are of severe reactions to more extensively hydrolyzed protein sources.* For these children, only complete removal from the implicated protein source seems effective, and in one child with sensitivity to milk, ingestion of beef also resulted in an allergic reaction, though milder. Colic Nonetheless, in a study of colic, changing from a cow’s milk formula to a hydrolyzed casein formula, -about 10% to 15% of infants appeared to cry less when fed the hydrolyzed casein formula. However, marked day-to-day irritability occurred with either formula. It was emphasized that this type of study should not be confused with demonstration of milk allergy.3 Acute Diarrhea A number of studies evaluated the follow-up treatment of infants and children recovering from acute diarrhea.4, 5 More than 50 years ago, Holt and Chung recommended feeding through diarrhea1 episodes.’ Nonetheless, many suggested regimens to “put the bowel at rest” and withheld food. In the past several years, widespread adoption of the practice of oral rehydration with modifications of the World Health Organization (WHO) oral rehydration solution markedly decreased hospital admissions due to dehydration. In the past year, Margolis and coworkers showed no difference in recovery in those .children with mild diarrhea who were fed during the diarrhea1 episode, compared with those who were not fed.4 Further, Haffejee found no difference in rate of recovery in those infants fed lactose-containing food versus those fed lactose-free food if the stools contained no sugar.5 These studies support the recommendations of the WHO over a decade ago when high-caloric-density food was recommended for infants with diarrhea and

The Liabilities of Iron Deficiency

Abstract Iron has been recognized as a potent hematinic since the inception of hematology as a clinical discipline. Even ancient civilizations believed in the beneficial effects of medicinal iron. Nevertheless, the precise functional liabilities of iron lack remain the subject of continuing debate. The consequences of iron deficiency, particularly from a socioeconomic standpoint, are especially important in light of its high global prevalence. A recent review of the literature indicates that approximately 30% of the estimated world population of nearly 4.5 billion are anemic, and at least half of these, 500 to 600 million people, are believed to have iron deficiency anemia.

The liabilities of iron deficiency

Iron has been recognized as a potent hematinic since the inception of hematology as a clinical discipline. Even ancient civilizations believed in the beneficial effects of medicinal iron. Nevertheless, the precise functional liabilities of iron lack remain the subject of continuing debate. The consequences of iron deficiency, particularly from a socioeconomic standpoint, are especially important in light of its high global prevalence. A recent review of the literature indicates that approximately 30% of the estimated world population of nearly 4.5 billion are anemic, and at least half of these, 500 to 600 million people, are believed to have iron deficiency anemia.

Consequences of iron deficiency on photosynthetic and respiratory electron transport in blue-green algae

Growth of Aphanocapsa in low iron media resulted in a decrease of the endogenous iron pool. Below a critical concentration photosynthetic electron transfer was specifically depressed. This was caused by a strong inhibition of the synthesis of cytochromes b-559 of PSII, cytochromes b-563, f-557, and the 'Rieske' Fe-S center of the cytochrome complex and especially the Fe-S centers of PSI. The influence of iron limitation on respiration and chlorphyll formation was negligible.