This article addresses the event-triggered consensus problem of multiagent systems (MASs) with packet losses. The packet losses are not restricted to be identical, and a hybrid systems framework is proposed to handle the considered problem with or without leader in a unified framework. Distributed control law is constructed based on an estimator, whose dynamics are related to whether packet losses occur. A novel hybrid event-triggering mechanism (ETM) is proposed, and a lower bound of the interevent times is enforced to guarantee Zeno-freeness. For stability analysis, a unified hybrid model is constructed to describe the dynamics of MAS with or without leader. In accordance to this model, how to design the hybrid ETM and consensus analysis are formally developed, and the maximum allowable successive packet losses can be explicitly computed. Moreover, even if there exist nonlinearities and disturbances in system dynamics, and the leader has nonzero input, the proposed method can still be applied. Finally, examples are provided to illustrate the superiority of the proposed method.